Compile Data Set for Download or QSAR
Report error Found 30 Enz. Inhib. hit(s) with all data for entry = 50027603
TargetCyclin-dependent kinase 2(Human)
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50246406BDBM50246406(2-fluoro-4-(5-fluoro-4-(1-isopropyl-2-methyl-1H-im...)
Affinity DataIC50: 1nMAssay Description:Inhibition of CDK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCyclin-dependent kinase 2(Human)
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50245910BDBM50245910((4-(5-fluoro-4-(1-isopropyl-2-methyl-1H-imidazol-5...)
Affinity DataIC50: 2nMAssay Description:Inhibition of CDK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCyclin-dependent kinase 1(Human)
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50246408BDBM50246408((4-(5-fluoro-4-(1-isopropyl-2-methyl-1H-imidazol-5...)
Affinity DataIC50: 2nMAssay Description:Inhibition of CDK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCyclin-dependent kinase 2(Human)
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50246408BDBM50246408((4-(5-fluoro-4-(1-isopropyl-2-methyl-1H-imidazol-5...)
Affinity DataIC50: 2nMAssay Description:Inhibition of CDK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCyclin-dependent kinase 2(Human)
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50245913BDBM50245913((4-(4-(1-isopropyl-2-methyl-1H-imidazol-5-yl)pyrim...)
Affinity DataIC50: 2nMAssay Description:Inhibition of CDK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCyclin-dependent kinase 2(Human)
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50245865BDBM50245865(N-(4-{[(3S)-3-(dimethylamino)pyrrolidin-1-yl]carbo...)
Affinity DataIC50: 2nMAssay Description:Inhibition of CDK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCyclin-dependent kinase 2(Human)
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50245864BDBM50245864(N-(2-(dimethylamino)ethyl)-2-fluoro-4-(5-fluoro-4-...)
Affinity DataIC50: 2nMAssay Description:Inhibition of CDK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCyclin-dependent kinase 2(Human)
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50246407BDBM50246407(N-(2-(dimethylamino)ethyl)-2-fluoro-4-(4-(1-isopro...)
Affinity DataIC50: 3nMAssay Description:Inhibition of CDK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCyclin-dependent kinase 2(Human)
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50245911BDBM50245911((4-(4-(1-isopropyl-2-methyl-1H-imidazol-5-yl)pyrim...)
Affinity DataIC50: 4nMAssay Description:Inhibition of CDK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCyclin-dependent kinase 1(Human)
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50245910BDBM50245910((4-(5-fluoro-4-(1-isopropyl-2-methyl-1H-imidazol-5...)
Affinity DataIC50: 5nMAssay Description:Inhibition of CDK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCyclin-dependent kinase 2(Human)
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50245866BDBM50245866(((R)-3-(dimethylamino)pyrrolidin-1-yl)(4-(5-fluoro...)
Affinity DataIC50: 6nMAssay Description:Inhibition of CDK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCyclin-dependent kinase 2(Human)
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50246253BDBM50246253(AZD-5438 | 4-(1-isopropyl-2-methyl-1H-imidazol-5-y...)
Affinity DataIC50: 6nMAssay Description:Inhibition of CDK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCyclin-dependent kinase 1(Human)
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50245913BDBM50245913((4-(4-(1-isopropyl-2-methyl-1H-imidazol-5-yl)pyrim...)
Affinity DataIC50: 9nMAssay Description:Inhibition of CDK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCyclin-dependent kinase 2(Human)
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50246357BDBM50246357((4-(4-(1-isopropyl-2-methyl-1H-imidazol-5-yl)pyrim...)
Affinity DataIC50: 9nMAssay Description:Inhibition of CDK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCyclin-dependent kinase 1(Human)
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50245866BDBM50245866(((R)-3-(dimethylamino)pyrrolidin-1-yl)(4-(5-fluoro...)
Affinity DataIC50: 11nMAssay Description:Inhibition of CDK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCyclin-dependent kinase 2(Human)
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50246405BDBM50246405(2-fluoro-4-(4-(1-isopropyl-2-methyl-1H-imidazol-5-...)
Affinity DataIC50: 11nMAssay Description:Inhibition of CDK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCyclin-dependent kinase 1(Human)
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50245865BDBM50245865(N-(4-{[(3S)-3-(dimethylamino)pyrrolidin-1-yl]carbo...)
Affinity DataIC50: 11nMAssay Description:Inhibition of CDK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCyclin-dependent kinase 1(Human)
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50246406BDBM50246406(2-fluoro-4-(5-fluoro-4-(1-isopropyl-2-methyl-1H-im...)
Affinity DataIC50: 12nMAssay Description:Inhibition of CDK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCyclin-dependent kinase 2(Human)
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50246358BDBM50246358((4-(5-fluoro-4-(1-isopropyl-2-methyl-1H-imidazol-5...)
Affinity DataIC50: 18nMAssay Description:Inhibition of CDK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCyclin-dependent kinase 1(Human)
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50246407BDBM50246407(N-(2-(dimethylamino)ethyl)-2-fluoro-4-(4-(1-isopro...)
Affinity DataIC50: 29nMAssay Description:Inhibition of CDK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCyclin-dependent kinase 2(Human)
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50246404BDBM50246404(4-(5-fluoro-4-(1-isopropyl-2-methyl-1H-imidazol-5-...)
Affinity DataIC50: 36nMAssay Description:Inhibition of CDK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCyclin-dependent kinase 2(Human)
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50246359BDBM50246359(4-(4-(1-isopropyl-2-methyl-1H-imidazol-5-yl)pyrimi...)
Affinity DataIC50: 37nMAssay Description:Inhibition of CDK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCyclin-dependent kinase 1(Human)
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50246404BDBM50246404(4-(5-fluoro-4-(1-isopropyl-2-methyl-1H-imidazol-5-...)
Affinity DataIC50: 50nMAssay Description:Inhibition of CDK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCyclin-dependent kinase 1(Human)
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50246253BDBM50246253(AZD-5438 | 4-(1-isopropyl-2-methyl-1H-imidazol-5-y...)
Affinity DataIC50: 62nMAssay Description:Inhibition of CDK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCyclin-dependent kinase 1(Human)
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50246357BDBM50246357((4-(4-(1-isopropyl-2-methyl-1H-imidazol-5-yl)pyrim...)
Affinity DataIC50: 71nMAssay Description:Inhibition of CDK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCyclin-dependent kinase 1(Human)
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50245912BDBM50245912(((S)-3-(cyclopropylamino)pyrrolidin-1-yl)(4-(4-(1-...)
Affinity DataIC50: 100nMAssay Description:Inhibition of CDK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCyclin-dependent kinase 1(Human)
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50245911BDBM50245911((4-(4-(1-isopropyl-2-methyl-1H-imidazol-5-yl)pyrim...)
Affinity DataIC50: 120nMAssay Description:Inhibition of CDK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCyclin-dependent kinase 1(Human)
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50246358BDBM50246358((4-(5-fluoro-4-(1-isopropyl-2-methyl-1H-imidazol-5...)
Affinity DataIC50: 130nMAssay Description:Inhibition of CDK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCyclin-dependent kinase 1(Human)
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50246405BDBM50246405(2-fluoro-4-(4-(1-isopropyl-2-methyl-1H-imidazol-5-...)
Affinity DataIC50: 150nMAssay Description:Inhibition of CDK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCyclin-dependent kinase 1(Human)
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50246359BDBM50246359(4-(4-(1-isopropyl-2-methyl-1H-imidazol-5-yl)pyrimi...)
Affinity DataIC50: 180nMAssay Description:Inhibition of CDK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed