Compile Data Set for Download or QSAR
Report error Found 37 Enz. Inhib. hit(s) with all data for entry = 2967
TargetUDP-N-acetylmuramoylalanine--D-glutamate ligase(Escherichia coli (strain K12))
Lek Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 26455BDBM26455(MurD inhibitor (compound 40) | (2R)-2-({6-[(4-cyan...)
Affinity DataIC50: 8.50E+4nMpH: 8.6 T: 2°CAssay Description:The compounds were tested for their ability to inhibit the addition of D-[14C]Glu to UMA. The radioactive substrate and product were separated by re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2009
Entry Details Article
PubMed
TargetUDP-N-acetylmuramoylalanine--D-glutamate ligase(Escherichia coli (strain K12))
Lek Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 26454BDBM26454((2R)-2-({6-[(4-cyano-2-methoxyphenyl)methoxy]napht...)
Affinity DataIC50: 1.00E+5nMpH: 8.6 T: 2°CAssay Description:The compounds were tested for their ability to inhibit the addition of D-[14C]Glu to UMA. The radioactive substrate and product were separated by re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2009
Entry Details Article
PubMed
TargetUDP-N-acetylmuramoylalanine--D-glutamate ligase(Escherichia coli (strain K12))
Lek Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 26453BDBM26453((2R)-2-({6-[(4-cyanophenyl)methoxy]naphthalene-2-}...)
Affinity DataIC50: 1.05E+5nMpH: 8.6 T: 2°CAssay Description:The compounds were tested for their ability to inhibit the addition of D-[14C]Glu to UMA. The radioactive substrate and product were separated by re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2009
Entry Details Article
PubMed
TargetUDP-N-acetylmuramoylalanine--D-glutamate ligase(Escherichia coli (strain K12))
Lek Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 26456BDBM26456((2R)-2-({7-[(4-cyanophenyl)methoxy]naphthalene-2-}...)
Affinity DataIC50: 1.22E+5nMpH: 8.6 T: 2°CAssay Description:The compounds were tested for their ability to inhibit the addition of D-[14C]Glu to UMA. The radioactive substrate and product were separated by re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetUDP-N-acetylmuramoylalanine--D-glutamate ligase(Escherichia coli (strain K12))
Lek Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 26452BDBM26452((2R)-2-{[6-(3-phenylpropoxy)naphthalene-2-]sulfona...)
Affinity DataIC50: 1.32E+5nMpH: 8.6 T: 2°CAssay Description:The compounds were tested for their ability to inhibit the addition of D-[14C]Glu to UMA. The radioactive substrate and product were separated by re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2009
Entry Details Article
PubMed
TargetUDP-N-acetylmuramoylalanine--D-glutamate ligase(Escherichia coli (strain K12))
Lek Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 26445BDBM26445((2R)-2-{[6-(pentyloxy)naphthalene-2-]sulfonamido}p...)
Affinity DataIC50: 1.70E+5nMpH: 8.6 T: 2°CAssay Description:The compounds were tested for their ability to inhibit the addition of D-[14C]Glu to UMA. The radioactive substrate and product were separated by re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2009
Entry Details Article
PubMed
TargetUDP-N-acetylmuramoylalanine--D-glutamate ligase(Escherichia coli (strain K12))
Lek Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 26446BDBM26446((2R)-2-{[6-(hexyloxy)naphthalene-2-]sulfonamido}pe...)
Affinity DataIC50: 1.76E+5nMpH: 8.6 T: 2°CAssay Description:The compounds were tested for their ability to inhibit the addition of D-[14C]Glu to UMA. The radioactive substrate and product were separated by re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2009
Entry Details Article
PubMed
TargetUDP-N-acetylmuramoylalanine--D-glutamate ligase(Escherichia coli (strain K12))
Lek Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 26464BDBM26464((2R)-2-[(7-butoxynaphthalene-2-)sulfonamido]pentan...)
Affinity DataIC50: 1.80E+5nMAssay Description:The compounds were tested for their ability to inhibit the addition of D-[14C]Glu to UMA. The radioactive substrate and product were separated by re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2009
Entry Details Article
PubMed
TargetUDP-N-acetylmuramoylalanine--D-glutamate ligase(Escherichia coli (strain K12))
Lek Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 26447BDBM26447((2R)-2-{[6-(2-ethoxy-2-oxoethoxy)naphthalene-2-]su...)
Affinity DataIC50: 1.92E+5nMpH: 8.6 T: 2°CAssay Description:The compounds were tested for their ability to inhibit the addition of D-[14C]Glu to UMA. The radioactive substrate and product were separated by re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2009
Entry Details Article
PubMed
TargetUDP-N-acetylmuramoylalanine--D-glutamate ligase(Escherichia coli (strain K12))
Lek Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 26451BDBM26451((2R)-2-{[6-(benzyloxy)naphthalene-2-]sulfonamido}p...)
Affinity DataIC50: 2.39E+5nMpH: 8.6 T: 2°CAssay Description:The compounds were tested for their ability to inhibit the addition of D-[14C]Glu to UMA. The radioactive substrate and product were separated by re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2009
Entry Details Article
PubMed
TargetUDP-N-acetylmuramoylalanine--D-glutamate ligase(Escherichia coli (strain K12))
Lek Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 26444BDBM26444((2R)-2-[(6-butoxynaphthalene-2-)sulfonamido]pentan...)
Affinity DataIC50: 2.80E+5nMpH: 8.6 T: 2°CAssay Description:The compounds were tested for their ability to inhibit the addition of D-[14C]Glu to UMA. The radioactive substrate and product were separated by re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetUDP-N-acetylmuramoylalanine--D-glutamate ligase(Escherichia coli (strain K12))
Lek Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 26443BDBM26443((2R)-2-[(6-propoxynaphthalene-2-)sulfonamido]penta...)
Affinity DataIC50: 3.05E+5nMpH: 8.6 T: 2°CAssay Description:The compounds were tested for their ability to inhibit the addition of D-[14C]Glu to UMA. The radioactive substrate and product were separated by re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2009
Entry Details Article
PubMed
TargetUDP-N-acetylmuramoylalanine--D-glutamate ligase(Escherichia coli (strain K12))
Lek Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 26450BDBM26450((2R)-2-{[6-(cyclopentyloxy)naphthalene-2-]sulfonam...)
Affinity DataIC50: 4.00E+5nMpH: 8.6 T: 2°CAssay Description:The compounds were tested for their ability to inhibit the addition of D-[14C]Glu to UMA. The radioactive substrate and product were separated by re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2009
Entry Details Article
PubMed
TargetUDP-N-acetylmuramoylalanine--D-glutamate ligase(Escherichia coli (strain K12))
Lek Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 26442BDBM26442((2R)-2-[(6-methoxynaphthalene-2-)sulfonamido]penta...)
Affinity DataIC50: 5.90E+5nMpH: 8.6 T: 2°CAssay Description:The compounds were tested for their ability to inhibit the addition of D-[14C]Glu to UMA. The radioactive substrate and product were separated by re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2009
Entry Details Article
PubMed
TargetUDP-N-acetylmuramoylalanine--D-glutamate ligase(Escherichia coli (strain K12))
Lek Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 26448BDBM26448((2R)-2-{[6-(carboxymethoxy)naphthalene-2-]sulfonam...)
Affinity DataIC50: 6.30E+5nMpH: 8.6 T: 2°CAssay Description:The compounds were tested for their ability to inhibit the addition of D-[14C]Glu to UMA. The radioactive substrate and product were separated by re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2009
Entry Details Article
PubMed
TargetUDP-N-acetylmuramoylalanine--D-glutamate ligase(Escherichia coli (strain K12))
Lek Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 26460BDBM26460(MurD inhibitor (compound 39) | (2S)-2-[(6-butoxyna...)
Affinity DataIC50: 7.10E+5nMAssay Description:The compounds were tested for their ability to inhibit the addition of D-[14C]Glu to UMA. The radioactive substrate and product were separated by re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2009
Entry Details Article
PubMed
TargetUDP-N-acetylmuramoylalanine--D-glutamate ligase(Escherichia coli (strain K12))
Lek Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 26440BDBM26440((2R)-2-(naphthalene-2-sulfonamido)pentanedioic aci...)
Affinity DataIC50: 8.10E+5nMpH: 8.6 T: 2°CAssay Description:The compounds were tested for their ability to inhibit the addition of D-[14C]Glu to UMA. The radioactive substrate and product were separated by re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2009
Entry Details Article
PubMed
TargetUDP-N-acetylmuramoylalanine--D-glutamate ligase(Escherichia coli (strain K12))
Lek Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 26449BDBM26449((2R)-2-{[6-(3-carboxypropoxy)naphthalene-2-]sulfon...)
Affinity DataIC50: 1.00E+6nMpH: 8.6 T: 2°CAssay Description:The compounds were tested for their ability to inhibit the addition of D-[14C]Glu to UMA. The radioactive substrate and product were separated by re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2009
Entry Details Article
PubMed
TargetUDP-N-acetylmuramoylalanine--D-glutamate ligase(Escherichia coli (strain K12))
Lek Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 26465BDBM26465((2R)-2-[(5-butoxynaphthalene-1-)sulfonamido]pentan...)
Affinity DataIC50: 1.00E+6nMAssay Description:The compounds were tested for their ability to inhibit the addition of D-[14C]Glu to UMA. The radioactive substrate and product were separated by re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2009
Entry Details Article
PubMed
TargetUDP-N-acetylmuramoylalanine--D-glutamate ligase(Escherichia coli (strain K12))
Lek Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 26466BDBM26466((2R)-2-[(4-butoxynaphthalene-1-)sulfonamido]pentan...)
Affinity DataIC50: 1.00E+6nMAssay Description:The compounds were tested for their ability to inhibit the addition of D-[14C]Glu to UMA. The radioactive substrate and product were separated by re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2009
Entry Details Article
PubMed
TargetUDP-N-acetylmuramoylalanine--D-glutamate ligase(Escherichia coli (strain K12))
Lek Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 26461BDBM26461((2R)-2-[(6-butoxynaphthalen-2-yl)formamido]pentane...)
Affinity DataIC50: 1.00E+6nMAssay Description:The compounds were tested for their ability to inhibit the addition of D-[14C]Glu to UMA. The radioactive substrate and product were separated by re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2009
Entry Details Article
PubMed
TargetUDP-N-acetylmuramoylalanine--D-glutamate ligase(Escherichia coli (strain K12))
Lek Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 26462BDBM26462((2R)-2-{[(6-butoxynaphthalen-2-yl)methyl]amino}pen...)
Affinity DataIC50: 1.00E+6nMAssay Description:The compounds were tested for their ability to inhibit the addition of D-[14C]Glu to UMA. The radioactive substrate and product were separated by re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2009
Entry Details Article
PubMed
TargetUDP-N-acetylmuramoylalanine--D-glutamate ligase(Escherichia coli (strain K12))
Lek Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 26463BDBM26463((2R)-2-[(6-butoxynaphthalene-2-)(methyl)sulfonamid...)
Affinity DataIC50: 1.00E+6nMAssay Description:The compounds were tested for their ability to inhibit the addition of D-[14C]Glu to UMA. The radioactive substrate and product were separated by re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2009
Entry Details Article
PubMed
TargetUDP-N-acetylmuramoylalanine--D-glutamate ligase(Escherichia coli (strain K12))
Lek Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 24035BDBM24035(JMC517486 Compound 11c | (2R)-2-[(4-phenylbenzene)...)
Affinity DataIC50: 1.72E+6nMpH: 8.6 T: 2°CAssay Description:The compounds were tested for their ability to inhibit the addition of D-[14C]Glu to UMA. The radioactive substrate and product were separated by re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2009
Entry Details Article
PubMed
TargetUDP-N-acetylmuramoylalanine--D-glutamate ligase(Escherichia coli (strain K12))
Lek Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 26441BDBM26441((2R)-2-{[(2S)-2-(naphthalene-2-sulfonamido)propane...)
Affinity DataIC50: 2.00E+6nMpH: 8.6 T: 2°CAssay Description:The compounds were tested for their ability to inhibit the addition of D-[14C]Glu to UMA. The radioactive substrate and product were separated by re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2009
Entry Details Article
PubMed
TargetUDP-N-acetylmuramoylalanine--D-glutamate ligase(Escherichia coli (strain K12))
Lek Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 26457BDBM26457(4-[(6-butoxynaphthalene-2-)sulfonamido]butanoic ac...)
Affinity DataIC50: 2.00E+6nMAssay Description:The compounds were tested for their ability to inhibit the addition of D-[14C]Glu to UMA. The radioactive substrate and product were separated by re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2009
Entry Details Article
PubMed
TargetUDP-N-acetylmuramoylalanine--D-glutamate ligase(Escherichia coli (strain K12))
Lek Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 26458BDBM26458(2-[(6-butoxynaphthalene-2-)sulfonamido]acetic acid...)
Affinity DataIC50: 2.00E+6nMAssay Description:The compounds were tested for their ability to inhibit the addition of D-[14C]Glu to UMA. The radioactive substrate and product were separated by re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2009
Entry Details Article
PubMed
TargetUDP-N-acetylmuramoylalanine--D-glutamate ligase(Escherichia coli (strain K12))
Lek Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 26459BDBM26459(1,5-dimethyl (2R)-2-[(6-butoxynaphthalene-2-)sulfo...)
Affinity DataIC50: 2.00E+6nMAssay Description:The compounds were tested for their ability to inhibit the addition of D-[14C]Glu to UMA. The radioactive substrate and product were separated by re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2009
Entry Details Article
PubMed
TargetUDP-N-acetylmuramoylalanine--D-glutamate ligase(Escherichia coli (strain K12))
Lek Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 26434BDBM26434((2R)-2-[3-(3-hydroxyphenyl)propanamido]pentanedioi...)
Affinity DatapH: 8.6 T: 2°CAssay Description:The compounds were tested for their ability to inhibit the addition of D-[14C]Glu to UMA. The radioactive substrate and product were separated by re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2009
Entry Details Article
PubMed
TargetUDP-N-acetylmuramoylalanine--D-glutamate ligase(Escherichia coli (strain K12))
Lek Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 26435BDBM26435((2R)-2-[1-(1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl)...)
Affinity DatapH: 8.6 T: 2°CAssay Description:The compounds were tested for their ability to inhibit the addition of D-[14C]Glu to UMA. The radioactive substrate and product were separated by re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2009
Entry Details Article
PubMed
TargetUDP-N-acetylmuramoylalanine--D-glutamate ligase(Escherichia coli (strain K12))
Lek Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 26436BDBM26436((2R)-2-{[(2-chloro-4-fluorophenyl)methane]sulfonam...)
Affinity DatapH: 8.6 T: 2°CAssay Description:The compounds were tested for their ability to inhibit the addition of D-[14C]Glu to UMA. The radioactive substrate and product were separated by re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2009
Entry Details Article
PubMed
TargetUDP-N-acetylmuramoylalanine--D-glutamate ligase(Escherichia coli (strain K12))
Lek Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 26437BDBM26437((2R)-2-(phenylmethane)sulfonamidopentanedioic acid...)
Affinity DatapH: 8.6 T: 2°CAssay Description:The compounds were tested for their ability to inhibit the addition of D-[14C]Glu to UMA. The radioactive substrate and product were separated by re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2009
Entry Details Article
PubMed
TargetUDP-N-acetylmuramoylalanine--D-glutamate ligase(Escherichia coli (strain K12))
Lek Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 26438BDBM26438((2R)-2-[(4-acetamidobenzene)sulfonamido]pentanedio...)
Affinity DatapH: 8.6 T: 2°CAssay Description:The compounds were tested for their ability to inhibit the addition of D-[14C]Glu to UMA. The radioactive substrate and product were separated by re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2009
Entry Details Article
PubMed
TargetUDP-N-acetylmuramoylalanine--D-glutamate ligase(Escherichia coli (strain K12))
Lek Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 26439BDBM26439((2R)-2-[(4-methylbenzene)sulfonamido]pentanedioic ...)
Affinity DatapH: 8.6 T: 2°CAssay Description:The compounds were tested for their ability to inhibit the addition of D-[14C]Glu to UMA. The radioactive substrate and product were separated by re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2009
Entry Details Article
PubMed
TargetUDP-N-acetylmuramoylalanine--D-glutamate ligase(Escherichia coli (strain K12))
Lek Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 26430BDBM26430((2R)-2-[(2E)-3-phenylprop-2-enamido]pentanedioic a...)
Affinity DatapH: 8.6 T: 2°CAssay Description:The compounds were tested for their ability to inhibit the addition of D-[14C]Glu to UMA. The radioactive substrate and product were separated by re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2009
Entry Details Article
PubMed
TargetUDP-N-acetylmuramoylalanine--D-glutamate ligase(Escherichia coli (strain K12))
Lek Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 26432BDBM26432((2R)-2-[(3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl)...)
Affinity DatapH: 8.6 T: 2°CAssay Description:The compounds were tested for their ability to inhibit the addition of D-[14C]Glu to UMA. The radioactive substrate and product were separated by re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2009
Entry Details Article
PubMed
TargetUDP-N-acetylmuramoylalanine--D-glutamate ligase(Escherichia coli (strain K12))
Lek Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 26433BDBM26433((2R)-2-[2-(naphthalen-2-yloxy)acetamido]pentanedio...)
Affinity DatapH: 8.6 T: 2°CAssay Description:The compounds were tested for their ability to inhibit the addition of D-[14C]Glu to UMA. The radioactive substrate and product were separated by re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2009
Entry Details Article
PubMed