Compile Data Set for Download or QSAR
Report error Found 39 Enz. Inhib. hit(s) with all data for entry = 50027803
TargetEphrin type-B receptor 4(Human)
Institute of General Genetics

Curated by ChEMBL
LigandPNGBDBM50246774(3-(1,3-Dioxo-1,3-dihydro-2H-indolo[1',7':4,5,6]pyr...)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of human EPHB4More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Institute of General Genetics

Curated by ChEMBL
LigandPNGBDBM50246815(3-(1,3-Dioxo-1,3,9b,10-tetrahydro-2H-indolo[1',7':...)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of human IGF1RMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetInsulin receptor(Human)
Institute of General Genetics

Curated by ChEMBL
LigandPNGBDBM50246774(3-(1,3-Dioxo-1,3-dihydro-2H-indolo[1',7':4,5,6]pyr...)
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of human INSRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCyclin-dependent kinase 4(Human)
Institute of General Genetics

Curated by ChEMBL
LigandPNGBDBM50246774(3-(1,3-Dioxo-1,3-dihydro-2H-indolo[1',7':4,5,6]pyr...)
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of human CDK4/CycD1More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Institute of General Genetics

Curated by ChEMBL
LigandPNGBDBM50246774(3-(1,3-Dioxo-1,3-dihydro-2H-indolo[1',7':4,5,6]pyr...)
Affinity DataIC50: 3.30E+3nMAssay Description:Inhibition of human METMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCyclin-dependent kinase 2(Human)
Institute of General Genetics

Curated by ChEMBL
LigandPNGBDBM50246774(3-(1,3-Dioxo-1,3-dihydro-2H-indolo[1',7':4,5,6]pyr...)
Affinity DataIC50: 3.60E+3nMAssay Description:Inhibition of human CDK2/Cyc2More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Institute of General Genetics

Curated by ChEMBL
LigandPNGBDBM50246774(3-(1,3-Dioxo-1,3-dihydro-2H-indolo[1',7':4,5,6]pyr...)
Affinity DataIC50: 3.80E+3nMAssay Description:Inhibition of human SRCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetEphrin type-B receptor 4(Human)
Institute of General Genetics

Curated by ChEMBL
LigandPNGBDBM50246776(3-(1,3-Dioxo-1,3-dihydro-2H-indolo[1',7':4,5,6]pyr...)
Affinity DataIC50: 3.90E+3nMAssay Description:Inhibition of human EPHB4More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Institute of General Genetics

Curated by ChEMBL
LigandPNGBDBM50246774(3-(1,3-Dioxo-1,3-dihydro-2H-indolo[1',7':4,5,6]pyr...)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of human IGF1RMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Institute of General Genetics

Curated by ChEMBL
LigandPNGBDBM50246774(3-(1,3-Dioxo-1,3-dihydro-2H-indolo[1',7':4,5,6]pyr...)
Affinity DataIC50: 4.10E+3nMAssay Description:Inhibition of human VEGFR2More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
Institute of General Genetics

Curated by ChEMBL
LigandPNGBDBM50246774(3-(1,3-Dioxo-1,3-dihydro-2H-indolo[1',7':4,5,6]pyr...)
Affinity DataIC50: 4.20E+3nMAssay Description:Inhibition of human PDGFRbetaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCyclin-dependent kinase 2(Human)
Institute of General Genetics

Curated by ChEMBL
LigandPNGBDBM50246730(3-(1,3-Dioxo-1,3,9b,10-tetrahydro-2H-indolo[1',7':...)
Affinity DataIC50: 4.30E+3nMAssay Description:Inhibition of human CDK2/Cyc2More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Institute of General Genetics

Curated by ChEMBL
LigandPNGBDBM50246815(3-(1,3-Dioxo-1,3,9b,10-tetrahydro-2H-indolo[1',7':...)
Affinity DataIC50: 4.30E+3nMAssay Description:Inhibition of human VEGFR2More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase receptor UFO(Human)
Institute of General Genetics

Curated by ChEMBL
LigandPNGBDBM50246774(3-(1,3-Dioxo-1,3-dihydro-2H-indolo[1',7':4,5,6]pyr...)
Affinity DataIC50: 4.40E+3nMAssay Description:Inhibition of human AXLMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetFocal adhesion kinase 1(Human)
Institute of General Genetics

Curated by ChEMBL
LigandPNGBDBM50246774(3-(1,3-Dioxo-1,3-dihydro-2H-indolo[1',7':4,5,6]pyr...)
Affinity DataIC50: 4.40E+3nMAssay Description:Inhibition of human FAKMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Institute of General Genetics

Curated by ChEMBL
LigandPNGBDBM50246774(3-(1,3-Dioxo-1,3-dihydro-2H-indolo[1',7':4,5,6]pyr...)
Affinity DataIC50: 4.60E+3nMAssay Description:Inhibition of human EGFRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 3(Human)
Institute of General Genetics

Curated by ChEMBL
LigandPNGBDBM50246774(3-(1,3-Dioxo-1,3-dihydro-2H-indolo[1',7':4,5,6]pyr...)
Affinity DataIC50: 4.70E+3nMAssay Description:Inhibition of human VEGFR3More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetInsulin receptor(Human)
Institute of General Genetics

Curated by ChEMBL
LigandPNGBDBM50246732(3-(1,3-Dioxo-1,3,9b,10-tetrahydro-2H-indolo[1',7':...)
Affinity DataIC50: 5.10E+3nMAssay Description:Inhibition of human INSRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCyclin-dependent kinase 2(Human)
Institute of General Genetics

Curated by ChEMBL
LigandPNGBDBM50246815(3-(1,3-Dioxo-1,3,9b,10-tetrahydro-2H-indolo[1',7':...)
Affinity DataIC50: 5.10E+3nMAssay Description:Inhibition of human CDK2/Cyc2More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCyclin-dependent kinase 2(Human)
Institute of General Genetics

Curated by ChEMBL
LigandPNGBDBM50246732(3-(1,3-Dioxo-1,3,9b,10-tetrahydro-2H-indolo[1',7':...)
Affinity DataIC50: 5.30E+3nMAssay Description:Inhibition of human CDK2/Cyc2More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCyclin-dependent kinase 4(Human)
Institute of General Genetics

Curated by ChEMBL
LigandPNGBDBM50246732(3-(1,3-Dioxo-1,3,9b,10-tetrahydro-2H-indolo[1',7':...)
Affinity DataIC50: 5.70E+3nMAssay Description:Inhibition of human CDK4/CycD1More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCyclin-dependent kinase 4(Human)
Institute of General Genetics

Curated by ChEMBL
LigandPNGBDBM50246776(3-(1,3-Dioxo-1,3-dihydro-2H-indolo[1',7':4,5,6]pyr...)
Affinity DataIC50: 6.20E+3nMAssay Description:Inhibition of human CDK4/CycD1More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCyclin-dependent kinase 2(Human)
Institute of General Genetics

Curated by ChEMBL
LigandPNGBDBM50246776(3-(1,3-Dioxo-1,3-dihydro-2H-indolo[1',7':4,5,6]pyr...)
Affinity DataIC50: 6.30E+3nMAssay Description:Inhibition of human CDK2/Cyc2More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetInsulin receptor(Human)
Institute of General Genetics

Curated by ChEMBL
LigandPNGBDBM50246776(3-(1,3-Dioxo-1,3-dihydro-2H-indolo[1',7':4,5,6]pyr...)
Affinity DataIC50: 6.30E+3nMAssay Description:Inhibition of human INSRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
Institute of General Genetics

Curated by ChEMBL
LigandPNGBDBM50246776(3-(1,3-Dioxo-1,3-dihydro-2H-indolo[1',7':4,5,6]pyr...)
Affinity DataIC50: 6.70E+3nMAssay Description:Inhibition of human PDGFRbetaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Institute of General Genetics

Curated by ChEMBL
LigandPNGBDBM50246732(3-(1,3-Dioxo-1,3,9b,10-tetrahydro-2H-indolo[1',7':...)
Affinity DataIC50: 6.70E+3nMAssay Description:Inhibition of human METMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCyclin-dependent kinase 2(Human)
Institute of General Genetics

Curated by ChEMBL
LigandPNGBDBM50246731(3-(1,3-Dioxo-1,3,9b,10-tetrahydro-2H-indolo[1',7':...)
Affinity DataIC50: 6.80E+3nMAssay Description:Inhibition of human CDK2/Cyc2More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCyclin-dependent kinase 4(Human)
Institute of General Genetics

Curated by ChEMBL
LigandPNGBDBM50246773(3-(1,3-Dioxo-1,3,9b,10-tetrahydro-2H-indolo[1',7':...)
Affinity DataIC50: 6.90E+3nMAssay Description:Inhibition of human CDK4/CycD1More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Institute of General Genetics

Curated by ChEMBL
LigandPNGBDBM50246776(3-(1,3-Dioxo-1,3-dihydro-2H-indolo[1',7':4,5,6]pyr...)
Affinity DataIC50: 7.40E+3nMAssay Description:Inhibition of human METMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Institute of General Genetics

Curated by ChEMBL
LigandPNGBDBM50246774(3-(1,3-Dioxo-1,3-dihydro-2H-indolo[1',7':4,5,6]pyr...)
Affinity DataIC50: 7.70E+3nMAssay Description:Inhibition of human ERBB2More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCyclin-dependent kinase 2(Human)
Institute of General Genetics

Curated by ChEMBL
LigandPNGBDBM50246775(2-[3-(4,5-Dihydro-1H-imidazol-2-ylsulfanyl)propyl]...)
Affinity DataIC50: 7.70E+3nMAssay Description:Inhibition of human CDK2/Cyc2More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCyclin-dependent kinase 4(Human)
Institute of General Genetics

Curated by ChEMBL
LigandPNGBDBM50246815(3-(1,3-Dioxo-1,3,9b,10-tetrahydro-2H-indolo[1',7':...)
Affinity DataIC50: 7.90E+3nMAssay Description:Inhibition of human CDK4/CycD1More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetAngiopoietin-1 receptor(Human)
Institute of General Genetics

Curated by ChEMBL
LigandPNGBDBM50246815(3-(1,3-Dioxo-1,3,9b,10-tetrahydro-2H-indolo[1',7':...)
Affinity DataIC50: 8.90E+3nMAssay Description:Inhibition of human TIE2More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
Institute of General Genetics

Curated by ChEMBL
LigandPNGBDBM50246774(3-(1,3-Dioxo-1,3-dihydro-2H-indolo[1',7':4,5,6]pyr...)
Affinity DataIC50: 9.00E+3nMAssay Description:Inhibition of human AKT1More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Institute of General Genetics

Curated by ChEMBL
LigandPNGBDBM50246815(3-(1,3-Dioxo-1,3,9b,10-tetrahydro-2H-indolo[1',7':...)
Affinity DataIC50: 9.50E+3nMAssay Description:Inhibition of human EGFRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 3(Human)
Institute of General Genetics

Curated by ChEMBL
LigandPNGBDBM50246815(3-(1,3-Dioxo-1,3,9b,10-tetrahydro-2H-indolo[1',7':...)
Affinity DataIC50: 9.60E+3nMAssay Description:Inhibition of human VEGFR3More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNUAK family SNF1-like kinase 1(Human)
Institute of General Genetics

Curated by ChEMBL
LigandPNGBDBM50246776(3-(1,3-Dioxo-1,3-dihydro-2H-indolo[1',7':4,5,6]pyr...)
Affinity DataIC50: 9.70E+3nMAssay Description:Inhibition of human ARK5More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PLK1(Human)
Institute of General Genetics

Curated by ChEMBL
LigandPNGBDBM50246774(3-(1,3-Dioxo-1,3-dihydro-2H-indolo[1',7':4,5,6]pyr...)
Affinity DataIC50: 9.90E+3nMAssay Description:Inhibition of human PLK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Institute of General Genetics

Curated by ChEMBL
LigandPNGBDBM50246776(3-(1,3-Dioxo-1,3-dihydro-2H-indolo[1',7':4,5,6]pyr...)
Affinity DataIC50: 9.90E+3nMAssay Description:Inhibition of human EGFRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed