Compile Data Set for Download or QSAR
Report error Found 72 Enz. Inhib. hit(s) with all data for entry = 3083
LigandChemical structure of BindingDB Monomer ID 27793BDBM27793(2-{[2-({5-[2-(dimethylamino)acetamido]-2-methoxy-4...)
Affinity DataIC50: 0.5nMpH: 7.5 T: 2°CAssay Description:Assays are performed in 384-well microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified activated GST-IGF-1R in th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 27799BDBM27799(2-{[2-({1-[2-(dimethylamino)acetyl]-5-methoxy-2,3-...)
Affinity DataIC50: 1nMpH: 7.5 T: 2°CAssay Description:Assays are performed in 384-well microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified activated GST-IGF-1R in th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 27803BDBM27803(2-fluoro-6-{[2-({5-methoxy-1-[2-(pyrrolidin-1-yl)a...)
Affinity DataIC50: 1nMpH: 7.5 T: 2°CAssay Description:Assays are performed in 384-well microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified activated GST-IGF-1R in th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 27814BDBM27814(2-{[2-({1-[2-(dimethylamino)acetyl]-6-methoxy-1,2,...)
Affinity DataIC50: 1nMAssay Description:Assays are performed in 384-well microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified activated GST-IGF-1R in th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 27804BDBM27804(2-{[2-({1-[2-(azetidin-1-yl)acetyl]-5-methoxy-2,3-...)
Affinity DataIC50: 1nMpH: 7.5 T: 2°CAssay Description:Assays are performed in 384-well microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified activated GST-IGF-1R in th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 27815BDBM27815(2-fluoro-6-{[2-({6-methoxy-1-[2-(piperidin-1-yl)ac...)
Affinity DataIC50: 1nMAssay Description:Assays are performed in 384-well microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified activated GST-IGF-1R in th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 27792BDBM27792(2-{[2-({5-[2-(dimethylamino)acetamido]-2-methoxyph...)
Affinity DataIC50: 1nMpH: 7.5 T: 2°CAssay Description:Assays are performed in 384-well microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified activated GST-IGF-1R in th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 27798BDBM27798(2-fluoro-6-{[2-({5-methoxy-1-[2-(methylamino)acety...)
Affinity DataIC50: 2nMpH: 7.5 T: 2°CAssay Description:Assays are performed in 384-well microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified activated GST-IGF-1R in th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 27783BDBM27783(CHEMBL507625 | BMCL19469 Compound 13 | 2-fluoro-6-...)
Affinity DataIC50: 2nMpH: 7.5 T: 2°CAssay Description:Assays are performed in 384-well microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified activated GST-IGF-1R in th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 27802BDBM27802(2-{[2-({1-[2-(diethylamino)acetyl]-5-methoxy-2,3-d...)
Affinity DataIC50: 2nMpH: 7.5 T: 2°CAssay Description:Assays are performed in 384-well microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified activated GST-IGF-1R in th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 27817BDBM27817(2-{[2-({1-[2-(dimethylamino)acetyl]-5-methoxy-2,3-...)
Affinity DataIC50: 2nMAssay Description:Assays are performed in 384-well microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified activated GST-IGF-1R in th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 27800BDBM27800(2-({2-[(1-{2-[ethyl(methyl)amino]acetyl}-5-methoxy...)
Affinity DataIC50: 3nMpH: 7.5 T: 2°CAssay Description:Assays are performed in 384-well microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified activated GST-IGF-1R in th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 27784BDBM27784(2-fluoro-6-{[2-({2-methoxy-5-[4-(propan-2-yl)piper...)
Affinity DataIC50: 4nMpH: 7.5 T: 2°CAssay Description:Assays are performed in 384-well microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified activated GST-IGF-1R in th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 27811BDBM27811(2-fluoro-6-({2-[(5-methoxy-1-{3-[4-(propan-2-yl)pi...)
Affinity DataIC50: 4nMAssay Description:Assays are performed in 384-well microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified activated GST-IGF-1R in th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 27797BDBM27797(2-[(2-{[1-(2-aminoacetyl)-5-methoxy-2,3-dihydro-1H...)
Affinity DataIC50: 4nMpH: 7.5 T: 2°CAssay Description:Assays are performed in 384-well microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified activated GST-IGF-1R in th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 27810BDBM27810(2-fluoro-6-{[2-({5-methoxy-1-[3-(morpholin-4-yl)pr...)
Affinity DataIC50: 6nMAssay Description:Assays are performed in 384-well microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified activated GST-IGF-1R in th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 27790BDBM27790(2-fluoro-6-{[2-({2-methoxy-5-[(1-propylpiperidin-4...)
Affinity DataIC50: 6nMpH: 7.5 T: 2°CAssay Description:Assays are performed in 384-well microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified activated GST-IGF-1R in th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 27796BDBM27796(2-({2-[(1-acetyl-5-methoxy-2,3-dihydro-1H-indol-6-...)
Affinity DataIC50: 6nMpH: 7.5 T: 2°CAssay Description:Assays are performed in 384-well microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified activated GST-IGF-1R in th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 27809BDBM27809(2-{[2-({1-[3-(dimethylamino)propanoyl]-5-methoxy-2...)
Affinity DataIC50: 8nMAssay Description:Assays are performed in 384-well microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified activated GST-IGF-1R in th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 27786BDBM27786(2-{[2-({5-[3-(dimethylamino)propoxy]-2-methoxyphen...)
Affinity DataIC50: 8nMpH: 7.5 T: 2°CAssay Description:Assays are performed in 384-well microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified activated GST-IGF-1R in th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 27816BDBM27816(2-{[2-({1-[3-(dimethylamino)propanoyl]-6-methoxy-1...)
Affinity DataIC50: 10nMAssay Description:Assays are performed in 384-well microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified activated GST-IGF-1R in th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 27787BDBM27787(2-{[2-({4-chloro-5-[3-(dimethylamino)propoxy]-2-me...)
Affinity DataIC50: 13nMpH: 7.5 T: 2°CAssay Description:Assays are performed in 384-well microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified activated GST-IGF-1R in th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 27788BDBM27788(2-{[2-({5-[3-(dimethylamino)propyl]-2-methoxypheny...)
Affinity DataIC50: 13nMpH: 7.5 T: 2°CAssay Description:Assays are performed in 384-well microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified activated GST-IGF-1R in th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 27789BDBM27789(2-{[2-({5-[3-(dimethylamino)propyl]-2-methoxy-4-me...)
Affinity DataIC50: 13nMpH: 7.5 T: 2°CAssay Description:Assays are performed in 384-well microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified activated GST-IGF-1R in th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 27806BDBM27806(2-fluoro-6-{[2-({5-methoxy-1-[2-(morpholin-4-yl)ac...)
Affinity DataIC50: 13nMpH: 7.5 T: 2°CAssay Description:Assays are performed in 384-well microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified activated GST-IGF-1R in th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 27783BDBM27783(CHEMBL507625 | BMCL19469 Compound 13 | 2-fluoro-6-...)
Affinity DataIC50: 13nMpH: 7.4 T: 2°CAssay Description:Assays are performed in 384-well microtiter plates in reaction buffer containing substrate GST-biotin-C-JUN, ATP, and purified activated JNK1alpha1 i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 27785BDBM27785(2-fluoro-6-{[2-({2-methoxy-4-methyl-5-[4-(propan-2...)
Affinity DataIC50: 20nMpH: 7.5 T: 2°CAssay Description:Assays are performed in 384-well microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified activated GST-IGF-1R in th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 27813BDBM27813(2-({2-[(1-acetyl-6-methoxy-1,2,3,4-tetrahydroquino...)
Affinity DataIC50: 25nMAssay Description:Assays are performed in 384-well microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified activated GST-IGF-1R in th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 27791BDBM27791(2-{[2-({4-chloro-2-methoxy-5-[(1-propylpiperidin-4...)
Affinity DataIC50: 25nMpH: 7.5 T: 2°CAssay Description:Assays are performed in 384-well microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified activated GST-IGF-1R in th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 27805BDBM27805(2-fluoro-6-{[2-({1-[2-(1H-imidazol-1-yl)acetyl]-5-...)
Affinity DataIC50: 32nMpH: 7.5 T: 2°CAssay Description:Assays are performed in 384-well microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified activated GST-IGF-1R in th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 27808BDBM27808(2-fluoro-6-({2-[(5-methoxy-1-{2-[4-(propan-2-yl)pi...)
Affinity DataIC50: 32nMAssay Description:Assays are performed in 384-well microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified activated GST-IGF-1R in th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 27812BDBM27812(2-{[2-({1-[2-(dimethylamino)ethyl]-5-methoxy-2,3-d...)
Affinity DataIC50: 40nMAssay Description:Assays are performed in 384-well microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified activated GST-IGF-1R in th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 27801BDBM27801(2-fluoro-6-({2-[(5-methoxy-1-{2-[methoxy(methyl)am...)
Affinity DataIC50: 50nMpH: 7.5 T: 2°CAssay Description:Assays are performed in 384-well microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified activated GST-IGF-1R in th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 27794BDBM27794(2-{[2-({5-[2-(dimethylamino)-N-methylacetamido]-2-...)
Affinity DataIC50: 50nMpH: 7.5 T: 2°CAssay Description:Assays are performed in 384-well microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified activated GST-IGF-1R in th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 27795BDBM27795(2-{[2-({5-[2-(dimethylamino)-N-methylacetamido]-2-...)
Affinity DataIC50: 63nMpH: 7.5 T: 2°CAssay Description:Assays are performed in 384-well microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified activated GST-IGF-1R in th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 27783BDBM27783(CHEMBL507625 | BMCL19469 Compound 13 | 2-fluoro-6-...)
Affinity DataIC50: 100nMpH: 7.5 T: 2°CAssay Description:Inhibitor binding to JNK3 was assessed by a fluorescence anisotropy competitive binding assay. The reaction mixture (JNK3 and fluorescently labelled ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 27812BDBM27812(2-{[2-({1-[2-(dimethylamino)ethyl]-5-methoxy-2,3-d...)
Affinity DataIC50: 100nMAssay Description:Assays are performed in 384-well microtiter plates in reaction buffer containing substrate GST-biotin-C-JUN, ATP, and purified activated JNK1alpha1 i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 27806BDBM27806(2-fluoro-6-{[2-({5-methoxy-1-[2-(morpholin-4-yl)ac...)
Affinity DataIC50: 126nMAssay Description:Assays are performed in 384-well microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified activated GST-IGF-1R in th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 27796BDBM27796(2-({2-[(1-acetyl-5-methoxy-2,3-dihydro-1H-indol-6-...)
Affinity DataIC50: 126nMAssay Description:Assays are performed in 384-well microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified activated GST-IGF-1R in th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 27810BDBM27810(2-fluoro-6-{[2-({5-methoxy-1-[3-(morpholin-4-yl)pr...)
Affinity DataIC50: 251nMAssay Description:Assays are performed in 384-well microtiter plates in reaction buffer containing substrate GST-biotin-C-JUN, ATP, and purified activated JNK1alpha1 i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 27789BDBM27789(2-{[2-({5-[3-(dimethylamino)propyl]-2-methoxy-4-me...)
Affinity DataIC50: 501nMAssay Description:Assays are performed in 384-well microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified activated GST-IGF-1R in th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 27786BDBM27786(2-{[2-({5-[3-(dimethylamino)propoxy]-2-methoxyphen...)
Affinity DataIC50: 631nMAssay Description:Assays are performed in 384-well microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified activated GST-IGF-1R in th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 27805BDBM27805(2-fluoro-6-{[2-({1-[2-(1H-imidazol-1-yl)acetyl]-5-...)
Affinity DataIC50: 631nMAssay Description:Assays are performed in 384-well microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified activated GST-IGF-1R in th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 27801BDBM27801(2-fluoro-6-({2-[(5-methoxy-1-{2-[methoxy(methyl)am...)
Affinity DataIC50: 794nMAssay Description:Assays are performed in 384-well microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified activated GST-IGF-1R in th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 27809BDBM27809(2-{[2-({1-[3-(dimethylamino)propanoyl]-5-methoxy-2...)
Affinity DataIC50: 794nMAssay Description:Assays are performed in 384-well microtiter plates in reaction buffer containing substrate GST-biotin-C-JUN, ATP, and purified activated JNK1alpha1 i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 27802BDBM27802(2-{[2-({1-[2-(diethylamino)acetyl]-5-methoxy-2,3-d...)
Affinity DataIC50: 1.00E+3nMAssay Description:Assays are performed in 384-well microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified activated GST-IGF-1R in th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 27797BDBM27797(2-[(2-{[1-(2-aminoacetyl)-5-methoxy-2,3-dihydro-1H...)
Affinity DataIC50: 1.00E+3nMAssay Description:Assays are performed in 384-well microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified activated GST-IGF-1R in th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 27787BDBM27787(2-{[2-({4-chloro-5-[3-(dimethylamino)propoxy]-2-me...)
Affinity DataIC50: 1.26E+3nMAssay Description:Assays are performed in 384-well microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified activated GST-IGF-1R in th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 27790BDBM27790(2-fluoro-6-{[2-({2-methoxy-5-[(1-propylpiperidin-4...)
Affinity DataIC50: 1.26E+3nMAssay Description:Assays are performed in 384-well microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified activated GST-IGF-1R in th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 27803BDBM27803(2-fluoro-6-{[2-({5-methoxy-1-[2-(pyrrolidin-1-yl)a...)
Affinity DataIC50: 1.26E+3nMAssay Description:Assays are performed in 384-well microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified activated GST-IGF-1R in th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2009
Entry Details Article
PubMed
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