Compile Data Set for Download or QSAR
maximum 50k data
Found 62 Enz. Inhib. hit(s) with all data for entry = 50027878
TargetSecreted frizzled-related protein 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50265547(CHEMBL455476 | N-{1-[1-(3,3-Dimethylbutanoyl)-L-pr...)
Affinity DataIC50:  20nMAssay Description:Binding affinity to human purified SARP2 by fluorescent polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSecreted frizzled-related protein 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50265555((2S)-N-Phenyl-2-{[4-({[5-(phenylsulfonyl)-2-(trifl...)
Affinity DataIC50:  20nMAssay Description:Binding affinity to human purified SARP2 by fluorescent polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSecreted frizzled-related protein 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50265554((2S)-N-(tert-Butyl)-2-{[4-({[5-(phenylsulfonyl)-2-...)
Affinity DataIC50:  20nMAssay Description:Binding affinity to human purified SARP2 by fluorescent polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSecreted frizzled-related protein 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50265553((2S)-N-Ethyl-2-{[4-({[5-(phenylsulfonyl)-2-(triflu...)
Affinity DataIC50:  30nMAssay Description:Binding affinity to human purified SARP2 by fluorescent polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSecreted frizzled-related protein 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50265499(CHEMBL495534 | N-[1-(1H-Imidazol-1-ylacetyl)piperi...)
Affinity DataIC50:  30nMAssay Description:Binding affinity to human purified SARP2 by fluorescent polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSecreted frizzled-related protein 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50265583(CHEMBL451431 | N-{1-[1-(3,3-Dimethylbutyl)-L-proly...)
Affinity DataIC50:  30nMAssay Description:Binding affinity to human purified SARP2 by fluorescent polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSecreted frizzled-related protein 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50265580((2S)-N,N-Dimethyl-2-{[4-({[5-(phenylsulfonyl)-2-(t...)
Affinity DataIC50:  30nMAssay Description:Binding affinity to human purified SARP2 by fluorescent polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSecreted frizzled-related protein 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50265581(CHEMBL505036 | N-{1-[1-(Morpholin-4-ylcarbonyl)-L-...)
Affinity DataIC50:  40nMAssay Description:Binding affinity to human purified SARP2 by fluorescent polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSecreted frizzled-related protein 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50265584(CHEMBL503281 | N-{1-[1-(Cyclohexylmethyl)-L-prolyl...)
Affinity DataIC50:  40nMAssay Description:Binding affinity to human purified SARP2 by fluorescent polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSecreted frizzled-related protein 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50265545(CHEMBL500903 | N-[1-(1-Isobutyryl-L-prolyl)piperid...)
Affinity DataIC50:  40nMAssay Description:Binding affinity to human purified SARP2 by fluorescent polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSecreted frizzled-related protein 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50265546(CHEMBL447079 | N-{1-[1-(2,2-Dimethylpropanoyl)-L-p...)
Affinity DataIC50:  40nMAssay Description:Binding affinity to human purified SARP2 by fluorescent polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSecreted frizzled-related protein 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50265549(CHEMBL507695 | N-{1-[1-(Cyclohexylcarbonyl)-L-prol...)
Affinity DataIC50:  50nMAssay Description:Binding affinity to human purified SARP2 by fluorescent polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSecreted frizzled-related protein 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50265500((S)-tert-butyl 2-(4-(5-(phenylsulfonyl)-2-(trifluo...)
Affinity DataIC50:  60nMAssay Description:Binding affinity to human purified SARP2 by fluorescent polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSecreted frizzled-related protein 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50265550(CHEMBL510748 | N-[1-(1-Benzoyl-L-prolyl)piperidin-...)
Affinity DataIC50:  70nMAssay Description:Binding affinity to human purified SARP2 by fluorescent polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSecreted frizzled-related protein 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50265552(CHEMBL454478 | N-[1-(1-Isonicotinoyl-L-prolyl)pipe...)
Affinity DataIC50:  70nMAssay Description:Binding affinity to human purified SARP2 by fluorescent polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSecreted frizzled-related protein 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50265548(CHEMBL501332 | N-[1-(N,N-Dimethylglycyl-L-prolyl)p...)
Affinity DataIC50:  90nMAssay Description:Binding affinity to human purified SARP2 by fluorescent polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSecreted frizzled-related protein 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50265505(CHEMBL525899 | N-[1-(5-oxo-L-Prolyl)piperidin-4-yl...)
Affinity DataIC50:  90nMAssay Description:Binding affinity to human purified SARP2 by fluorescent polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSecreted frizzled-related protein 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50265480(CHEMBL523726 | N-[1-(Morpholin-4-ylacetyl)piperidi...)
Affinity DataIC50:  100nMAssay Description:Binding affinity to human purified SARP2 by fluorescent polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSecreted frizzled-related protein 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50265551(CHEMBL462363 | N-(1-{1-[4-(Dimethylamino)benzoyl]-...)
Affinity DataIC50:  110nMAssay Description:Binding affinity to human purified SARP2 by fluorescent polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSecreted frizzled-related protein 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50265479(5-(Phenylsulfonyl)-N-[1-(pyrrolidin-1-ylacetyl)pip...)
Affinity DataIC50:  110nMAssay Description:Binding affinity to human purified SARP2 by fluorescent polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSecreted frizzled-related protein 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50265503((S)-5-(phenylsulfonyl)-N-(1-(pyrrolidine-2-carbony...)
Affinity DataIC50:  110nMAssay Description:Binding affinity to human purified SARP2 by fluorescent polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSecreted frizzled-related protein 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50265501((R)-tert-butyl 2-(4-(5-(phenylsulfonyl)-2-(trifluo...)
Affinity DataIC50:  120nMAssay Description:Binding affinity to human purified SARP2 by fluorescent polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSecreted frizzled-related protein 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50265582(CHEMBL496581 | N-[1-(1-Methyl-L-prolyl)piperidin-4...)
Affinity DataIC50:  120nMAssay Description:Binding affinity to human purified SARP2 by fluorescent polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSecreted frizzled-related protein 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50265502(CHEMBL504979 | tert-Butyl(5S)-2-oxo-5-{[4-({[5-(Ph...)
Affinity DataIC50:  130nMAssay Description:Binding affinity to human purified SARP2 by fluorescent polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSecreted frizzled-related protein 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50265481(5-(Phenylsulfonyl)-N-[1-(piperazin-1-ylacetyl)pipe...)
Affinity DataIC50:  140nMAssay Description:Binding affinity to human purified SARP2 by fluorescent polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSecreted frizzled-related protein 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50265544(CHEMBL525970 | N-[1-(1-Acetyl-L-prolyl)piperidin-4...)
Affinity DataIC50:  160nMAssay Description:Binding affinity to human purified SARP2 by fluorescent polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSecreted frizzled-related protein 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50265504((R)-5-(phenylsulfonyl)-N-(1-(pyrrolidine-2-carbony...)
Affinity DataIC50:  200nMAssay Description:Binding affinity to human purified SARP2 by fluorescent polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSecreted frizzled-related protein 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50265468(CHEMBL497177 | N-[1-(N-Methylglycyl)piperidin-4-yl...)
Affinity DataIC50:  200nMAssay Description:Binding affinity to human purified SARP2 by fluorescent polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSecreted frizzled-related protein 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50265469(CHEMBL497383 | N-[1-(N,N-Dimethylglycyl)piperidin-...)
Affinity DataIC50:  300nMAssay Description:Binding affinity to human purified SARP2 by fluorescent polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSecreted frizzled-related protein 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50265467(5-(Phenylsulfonyl)-N-piperidin-4-yl-2-(trifluorome...)
Affinity DataIC50:  500nMAssay Description:Binding affinity to human purified SARP2 by fluorescent polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSecreted frizzled-related protein 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50265585(CHEMBL511077 | N-[1-(1-Benzyl-L-prolyl)piperidin-4...)
Affinity DataIC50:  1.40E+3nMAssay Description:Binding affinity to human purified SARP2 by fluorescent polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene Wnt-3(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50265479(5-(Phenylsulfonyl)-N-[1-(pyrrolidin-1-ylacetyl)pip...)
Affinity DataEC50:  190nMAssay Description:Antagonist activity at human WNT3 expressed in human U2OS cells assessed as Wnt signaling after 16 to 18 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene Wnt-3(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50265469(CHEMBL497383 | N-[1-(N,N-Dimethylglycyl)piperidin-...)
Affinity DataEC50:  280nMAssay Description:Antagonist activity at human WNT3 expressed in human U2OS cells assessed as Wnt signaling after 16 to 18 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene Wnt-3(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50265468(CHEMBL497177 | N-[1-(N-Methylglycyl)piperidin-4-yl...)
Affinity DataEC50:  620nMAssay Description:Antagonist activity at human WNT3 expressed in human U2OS cells assessed as Wnt signaling after 16 to 18 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene Wnt-3(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50265467(5-(Phenylsulfonyl)-N-piperidin-4-yl-2-(trifluorome...)
Affinity DataEC50:  650nMAssay Description:Antagonist activity at human WNT3 expressed in human U2OS cells assessed as Wnt signaling after 16 to 18 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene Wnt-3(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50265585(CHEMBL511077 | N-[1-(1-Benzyl-L-prolyl)piperidin-4...)
Affinity DataEC50:  720nMAssay Description:Antagonist activity at human WNT3 expressed in human U2OS cells assessed as Wnt signaling after 16 to 18 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene Wnt-3(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50265584(CHEMBL503281 | N-{1-[1-(Cyclohexylmethyl)-L-prolyl...)
Affinity DataEC50:  320nMAssay Description:Antagonist activity at human WNT3 expressed in human U2OS cells assessed as Wnt signaling after 16 to 18 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene Wnt-3(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50265583(CHEMBL451431 | N-{1-[1-(3,3-Dimethylbutyl)-L-proly...)
Affinity DataEC50:  450nMAssay Description:Antagonist activity at human WNT3 expressed in human U2OS cells assessed as Wnt signaling after 16 to 18 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene Wnt-3(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50265582(CHEMBL496581 | N-[1-(1-Methyl-L-prolyl)piperidin-4...)
Affinity DataEC50:  230nMAssay Description:Antagonist activity at human WNT3 expressed in human U2OS cells assessed as Wnt signaling after 16 to 18 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene Wnt-3(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50265581(CHEMBL505036 | N-{1-[1-(Morpholin-4-ylcarbonyl)-L-...)
Affinity DataEC50:  280nMAssay Description:Antagonist activity at human WNT3 expressed in human U2OS cells assessed as Wnt signaling after 16 to 18 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene Wnt-3(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50265580((2S)-N,N-Dimethyl-2-{[4-({[5-(phenylsulfonyl)-2-(t...)
Affinity DataEC50:  160nMAssay Description:Antagonist activity at human WNT3 expressed in human U2OS cells assessed as Wnt signaling after 16 to 18 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene Wnt-3(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50265555((2S)-N-Phenyl-2-{[4-({[5-(phenylsulfonyl)-2-(trifl...)
Affinity DataEC50:  310nMAssay Description:Antagonist activity at human WNT3 expressed in human U2OS cells assessed as Wnt signaling after 16 to 18 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene Wnt-3(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50265554((2S)-N-(tert-Butyl)-2-{[4-({[5-(phenylsulfonyl)-2-...)
Affinity DataEC50:  30nMAssay Description:Antagonist activity at human WNT3 expressed in human U2OS cells assessed as Wnt signaling after 16 to 18 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene Wnt-3(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50265553((2S)-N-Ethyl-2-{[4-({[5-(phenylsulfonyl)-2-(triflu...)
Affinity DataEC50:  90nMAssay Description:Antagonist activity at human WNT3 expressed in human U2OS cells assessed as Wnt signaling after 16 to 18 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene Wnt-3(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50265552(CHEMBL454478 | N-[1-(1-Isonicotinoyl-L-prolyl)pipe...)
Affinity DataEC50:  350nMAssay Description:Antagonist activity at human WNT3 expressed in human U2OS cells assessed as Wnt signaling after 16 to 18 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene Wnt-3(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50265551(CHEMBL462363 | N-(1-{1-[4-(Dimethylamino)benzoyl]-...)
Affinity DataEC50:  830nMAssay Description:Antagonist activity at human WNT3 expressed in human U2OS cells assessed as Wnt signaling after 16 to 18 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene Wnt-3(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50265550(CHEMBL510748 | N-[1-(1-Benzoyl-L-prolyl)piperidin-...)
Affinity DataEC50:  380nMAssay Description:Antagonist activity at human WNT3 expressed in human U2OS cells assessed as Wnt signaling after 16 to 18 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene Wnt-3(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50265549(CHEMBL507695 | N-{1-[1-(Cyclohexylcarbonyl)-L-prol...)
Affinity DataEC50:  460nMAssay Description:Antagonist activity at human WNT3 expressed in human U2OS cells assessed as Wnt signaling after 16 to 18 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene Wnt-3(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50265548(CHEMBL501332 | N-[1-(N,N-Dimethylglycyl-L-prolyl)p...)
Affinity DataEC50:  310nMAssay Description:Antagonist activity at human WNT3 expressed in human U2OS cells assessed as Wnt signaling after 16 to 18 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene Wnt-3(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50265547(CHEMBL455476 | N-{1-[1-(3,3-Dimethylbutanoyl)-L-pr...)
Affinity DataEC50:  120nMAssay Description:Antagonist activity at human WNT3 expressed in human U2OS cells assessed as Wnt signaling after 16 to 18 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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