Compile Data Set for Download or QSAR
Report error Found 14 Enz. Inhib. hit(s) with all data for entry = 3136
TargetBile acid receptor(Human)
Exelixis

LigandChemical structure of BindingDB Monomer ID 28542BDBM28542(propan-2-yl 3-[(3,4-difluorophenyl)carbonyl]-1,1-d...)
Affinity DataEC50:  4nMpH: 7.0 T: 2°CAssay Description:The assays were performed using CV-1 African Green Monkey Kidney cells transfected with the vectors harboring human FXR, RXR, and luciferase reporter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2009
Entry Details Article
PubMed
TargetBile acid receptor(Human)
Exelixis

LigandChemical structure of BindingDB Monomer ID 28541BDBM28541(propan-2-yl 3-[(4-fluorophenyl)carbonyl]-1,1-dimet...)
Affinity DataEC50:  8nMpH: 7.0 T: 2°CAssay Description:The assays were performed using CV-1 African Green Monkey Kidney cells transfected with the vectors harboring human FXR, RXR, and luciferase reporter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2009
Entry Details Article
PubMed
TargetBile acid receptor(Human)
Exelixis

LigandChemical structure of BindingDB Monomer ID 28538BDBM28538(ethyl 3-[(3,4-difluorophenyl)carbonyl]-1,1-dimethy...)
Affinity DataEC50:  12nMpH: 7.0 T: 2°CAssay Description:The assays were performed using CV-1 African Green Monkey Kidney cells transfected with the vectors harboring human FXR, RXR, and luciferase reporter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2009
Entry Details Article
PubMed
TargetBile acid receptor(Human)
Exelixis

LigandChemical structure of BindingDB Monomer ID 28537BDBM28537(ethyl 3-[(4-fluorophenyl)carbonyl]-1,1-dimethyl-1H...)
Affinity DataEC50:  22nMpH: 7.0 T: 2°CAssay Description:The assays were performed using CV-1 African Green Monkey Kidney cells transfected with the vectors harboring human FXR, RXR, and luciferase reporter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2009
Entry Details Article
PubMed
TargetBile acid receptor(Human)
Exelixis

LigandChemical structure of BindingDB Monomer ID 28539BDBM28539(ethyl 3-[(4-chlorophenyl)carbonyl]-1,1-dimethyl-1H...)
Affinity DataEC50:  25nMpH: 7.0 T: 2°CAssay Description:The assays were performed using CV-1 African Green Monkey Kidney cells transfected with the vectors harboring human FXR, RXR, and luciferase reporter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2009
Entry Details Article
PubMed
TargetBile acid receptor(Human)
Exelixis

LigandChemical structure of BindingDB Monomer ID 28540BDBM28540(ethyl 3-[(4-methoxyphenyl)carbonyl]-1,1-dimethyl-1...)
Affinity DataEC50:  29nMpH: 7.0 T: 2°CAssay Description:The assays were performed using CV-1 African Green Monkey Kidney cells transfected with the vectors harboring human FXR, RXR, and luciferase reporter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2009
Entry Details Article
PubMed
TargetBile acid receptor(Human)
Exelixis

LigandChemical structure of BindingDB Monomer ID 28536BDBM28536(ethyl 3-[(3,4-difluorophenyl)carbonyl]-1-methyl-1H...)
Affinity DataEC50:  32nMpH: 7.0 T: 2°CAssay Description:The assays were performed using CV-1 African Green Monkey Kidney cells transfected with the vectors harboring human FXR, RXR, and luciferase reporter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2009
Entry Details Article
PubMed
TargetBile acid receptor(Human)
Exelixis

LigandChemical structure of BindingDB Monomer ID 28533BDBM28533(ethyl 3-[(4-fluorophenyl)carbonyl]-1-methyl-1H,2H,...)
Affinity DataEC50:  57nMpH: 7.0 T: 2°CAssay Description:The assays were performed using CV-1 African Green Monkey Kidney cells transfected with the vectors harboring human FXR, RXR, and luciferase reporter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2009
Entry Details Article
PubMed
TargetBile acid receptor(Human)
Exelixis

LigandChemical structure of BindingDB Monomer ID 28535BDBM28535(ethyl 3-[(4-methoxyphenyl)carbonyl]-1-methyl-1H,2H...)
Affinity DataEC50:  60nMpH: 7.0 T: 2°CAssay Description:The assays were performed using CV-1 African Green Monkey Kidney cells transfected with the vectors harboring human FXR, RXR, and luciferase reporter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2009
Entry Details Article
PubMed
TargetBile acid receptor(Human)
Exelixis

LigandChemical structure of BindingDB Monomer ID 28534BDBM28534(ethyl 3-[(4-chlorophenyl)carbonyl]-1-methyl-1H,2H,...)
Affinity DataEC50:  73nMpH: 7.0 T: 2°CAssay Description:The assays were performed using CV-1 African Green Monkey Kidney cells transfected with the vectors harboring human FXR, RXR, and luciferase reporter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2009
Entry Details Article
PubMed
TargetBile acid receptor(Human)
Exelixis

LigandChemical structure of BindingDB Monomer ID 28530BDBM28530(propan-2-yl 3-[(4-fluorophenyl)carbonyl]-1H,2H,3H,...)
Affinity DataEC50:  500nMpH: 7.0 T: 2°CAssay Description:The assays were performed using CV-1 African Green Monkey Kidney cells transfected with the vectors harboring human FXR, RXR, and luciferase reporter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2009
Entry Details Article
PubMed
TargetBile acid receptor(Human)
Exelixis

LigandChemical structure of BindingDB Monomer ID 28531BDBM28531(propyl 3-[(4-fluorophenyl)carbonyl]-1H,2H,3H,6H-az...)
Affinity DataEC50:  500nMpH: 7.0 T: 2°CAssay Description:The assays were performed using CV-1 African Green Monkey Kidney cells transfected with the vectors harboring human FXR, RXR, and luciferase reporter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2009
Entry Details Article
PubMed
TargetBile acid receptor(Human)
Exelixis

LigandChemical structure of BindingDB Monomer ID 28529BDBM28529(ethyl 3-[(4-fluorophenyl)carbonyl]-1H,2H,3H,6H-aze...)
Affinity DataEC50:  600nMpH: 7.0 T: 2°CAssay Description:The assays were performed using CV-1 African Green Monkey Kidney cells transfected with the vectors harboring human FXR, RXR, and luciferase reporter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2009
Entry Details Article
PubMed
TargetBile acid receptor(Human)
Exelixis

LigandChemical structure of BindingDB Monomer ID 28532BDBM28532(butyl 3-[(4-fluorophenyl)carbonyl]-1H,2H,3H,6H-aze...)
Affinity DataEC50:  1.10E+3nMpH: 7.0 T: 2°CAssay Description:The assays were performed using CV-1 African Green Monkey Kidney cells transfected with the vectors harboring human FXR, RXR, and luciferase reporter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2009
Entry Details Article
PubMed