BindingDB PrimarySearch

Found 6 Enz. Inhib. hit(s) with all data for entry = 50030234

Sodium-dependent noradrenaline transporter(Homo sapiens (Human))
Sirtris Pharmaceuticals

Curated by ChEMBL

BDBM50228363(CHEMBL257991 | N-(2-(3-(piperazin-1-ylmethyl)imida...)

IC50: 2.47E+3nMAssay Description:Inhibition of norepinephrine transporterMore data for this Ligand-Target Pair

Alpha-2A adrenergic receptor(Homo sapiens (Human))
Sirtris Pharmaceuticals

Curated by ChEMBL

BDBM50228363(CHEMBL257991 | N-(2-(3-(piperazin-1-ylmethyl)imida...)

IC50: 2.83E+3nMAssay Description:Inhibition of adrenergic alpha2A receptorMore data for this Ligand-Target Pair

Muscarinic acetylcholine receptor M2(Homo sapiens (Human))
Sirtris Pharmaceuticals

Curated by ChEMBL

BDBM50228363(CHEMBL257991 | N-(2-(3-(piperazin-1-ylmethyl)imida...)

IC50: 6.28E+3nMAssay Description:Inhibition of muscarinic M2 receptorMore data for this Ligand-Target Pair

Muscarinic acetylcholine receptor M1(Homo sapiens (Human))
Sirtris Pharmaceuticals

Curated by ChEMBL

BDBM50228363(CHEMBL257991 | N-(2-(3-(piperazin-1-ylmethyl)imida...)

IC50: 8.02E+3nMAssay Description:Inhibition of muscarinic M1 receptorMore data for this Ligand-Target Pair

Potassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Sirtris Pharmaceuticals

Curated by ChEMBL

BDBM50228363(CHEMBL257991 | N-(2-(3-(piperazin-1-ylmethyl)imida...)

IC50: >1.00E+4nMAssay Description:Inhibition of human ERG by patch clamp methodMore data for this Ligand-Target Pair

NAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
Sirtris Pharmaceuticals

Curated by ChEMBL

BDBM50228364(3,4,5-trimethoxy-N-(2-(3-(piperazin-1-ylmethyl)imi...)

Kd: 1.62E+4nMAssay Description:Binding affinity to SIRT1More data for this Ligand-Target Pair