Compile Data Set for Download or QSAR
maximum 50k data
Found 44 Enz. Inhib. hit(s) with all data for entry = 3132
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Gsk

LigandPNGBDBM28490((3R,5S)-5-[2-(4-{[3-chloro-4-(pyridin-2-ylmethoxy)...)
Affinity DataIC50:  30nMAssay Description:Assays were performed in 96-well polystyrene round-bottomed plates in reaction buffer containing biotinylated substrate and purified kinase in the pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Gsk

LigandPNGBDBM28502((3R,5S)-5-{2-[4-({1-[(3-fluorophenyl)methyl]-1H-in...)
Affinity DataIC50:  30nMpH: 7.5 T: 2°CAssay Description:Assays were performed in 96-well polystyrene round-bottomed plates in reaction buffer containing biotinylated substrate and purified kinase in the pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Gsk

LigandPNGBDBM28502((3R,5S)-5-{2-[4-({1-[(3-fluorophenyl)methyl]-1H-in...)
Affinity DataIC50:  30nMAssay Description:Assays were performed in 96-well polystyrene round-bottomed plates in reaction buffer containing biotinylated substrate and purified kinase in the pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Gsk

LigandPNGBDBM28503((3R,5S)-5-{2-[4-({1-[(2,5-difluorophenyl)methyl]-1...)
Affinity DataIC50:  33nMpH: 7.5 T: 2°CAssay Description:Assays were performed in 96-well polystyrene round-bottomed plates in reaction buffer containing biotinylated substrate and purified kinase in the pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Gsk

LigandPNGBDBM28503((3R,5S)-5-{2-[4-({1-[(2,5-difluorophenyl)methyl]-1...)
Affinity DataIC50:  35nMAssay Description:Assays were performed in 96-well polystyrene round-bottomed plates in reaction buffer containing biotinylated substrate and purified kinase in the pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Gsk

LigandPNGBDBM28490((3R,5S)-5-[2-(4-{[3-chloro-4-(pyridin-2-ylmethoxy)...)
Affinity DataIC50:  50nMpH: 7.5 T: 2°CAssay Description:Assays were performed in 96-well polystyrene round-bottomed plates in reaction buffer containing biotinylated substrate and purified kinase in the pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Gsk

LigandPNGBDBM28501((3R,5S)-5-(2-{4-[(1-benzyl-1H-indazol-5-yl)amino]t...)
Affinity DataIC50:  50nMAssay Description:Assays were performed in 96-well polystyrene round-bottomed plates in reaction buffer containing biotinylated substrate and purified kinase in the pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Gsk

LigandPNGBDBM28494((3R,5S)-5-[2-(4-{[3-chloro-4-(pyridin-2-yloxy)phen...)
Affinity DataIC50:  60nMAssay Description:Assays were performed in 96-well polystyrene round-bottomed plates in reaction buffer containing biotinylated substrate and purified kinase in the pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Gsk

LigandPNGBDBM28498((3R,5S)-5-(2-{4-[(4-benzylphenyl)amino]thieno[3,2-...)
Affinity DataIC50:  60nMAssay Description:Assays were performed in 96-well polystyrene round-bottomed plates in reaction buffer containing biotinylated substrate and purified kinase in the pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Gsk

LigandPNGBDBM28507((3R,5S)-5-(2-{4-[(1-benzyl-1H-indol-5-yl)amino]thi...)
Affinity DataIC50:  60nMAssay Description:Assays were performed in 96-well polystyrene round-bottomed plates in reaction buffer containing biotinylated substrate and purified kinase in the pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Gsk

LigandPNGBDBM28491((3R,5S)-5-[2-(4-{[3-chloro-4-(1,3-thiazol-4-ylmeth...)
Affinity DataIC50:  60nMAssay Description:Assays were performed in 96-well polystyrene round-bottomed plates in reaction buffer containing biotinylated substrate and purified kinase in the pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Gsk

LigandPNGBDBM28489((3R,5S)-5-{2-[4-({3-chloro-4-[(3-fluorophenyl)meth...)
Affinity DataIC50:  80nMpH: 7.5 T: 2°CAssay Description:Assays were performed in 96-well polystyrene round-bottomed plates in reaction buffer containing biotinylated substrate and purified kinase in the pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Gsk

LigandPNGBDBM28489((3R,5S)-5-{2-[4-({3-chloro-4-[(3-fluorophenyl)meth...)
Affinity DataIC50:  80nMAssay Description:Assays were performed in 96-well polystyrene round-bottomed plates in reaction buffer containing biotinylated substrate and purified kinase in the pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Gsk

LigandPNGBDBM28501((3R,5S)-5-(2-{4-[(1-benzyl-1H-indazol-5-yl)amino]t...)
Affinity DataIC50:  80nMpH: 7.5 T: 2°CAssay Description:Assays were performed in 96-well polystyrene round-bottomed plates in reaction buffer containing biotinylated substrate and purified kinase in the pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Gsk

LigandPNGBDBM28505((3R,5S)-5-{2-[4-({1-[(3-fluorobenzene)sulfonyl]-1H...)
Affinity DataIC50:  85nMAssay Description:Assays were performed in 96-well polystyrene round-bottomed plates in reaction buffer containing biotinylated substrate and purified kinase in the pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Gsk

LigandPNGBDBM28497((3R,5S)-5-[2-(4-{[(3-phenoxyphenyl)methyl]amino}th...)
Affinity DataIC50:  87nMAssay Description:Assays were performed in 96-well polystyrene round-bottomed plates in reaction buffer containing biotinylated substrate and purified kinase in the pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Gsk

LigandPNGBDBM28507((3R,5S)-5-(2-{4-[(1-benzyl-1H-indol-5-yl)amino]thi...)
Affinity DataIC50:  90nMpH: 7.5 T: 2°CAssay Description:Assays were performed in 96-well polystyrene round-bottomed plates in reaction buffer containing biotinylated substrate and purified kinase in the pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Gsk

LigandPNGBDBM28504((3R,5S)-5-{2-[4-({1-[1-(3-fluorophenyl)ethyl]-1H-i...)
Affinity DataIC50:  120nMpH: 7.5 T: 2°CAssay Description:Assays were performed in 96-well polystyrene round-bottomed plates in reaction buffer containing biotinylated substrate and purified kinase in the pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Gsk

LigandPNGBDBM28491((3R,5S)-5-[2-(4-{[3-chloro-4-(1,3-thiazol-4-ylmeth...)
Affinity DataIC50:  120nMpH: 7.5 T: 2°CAssay Description:Assays were performed in 96-well polystyrene round-bottomed plates in reaction buffer containing biotinylated substrate and purified kinase in the pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Gsk

LigandPNGBDBM28506((3R,5S)-5-[2-(4-{[1-(thiophene-2-sulfonyl)-1H-indo...)
Affinity DataIC50:  120nMAssay Description:Assays were performed in 96-well polystyrene round-bottomed plates in reaction buffer containing biotinylated substrate and purified kinase in the pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Gsk

LigandPNGBDBM28504((3R,5S)-5-{2-[4-({1-[1-(3-fluorophenyl)ethyl]-1H-i...)
Affinity DataIC50:  130nMAssay Description:Assays were performed in 96-well polystyrene round-bottomed plates in reaction buffer containing biotinylated substrate and purified kinase in the pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Gsk

LigandPNGBDBM28506((3R,5S)-5-[2-(4-{[1-(thiophene-2-sulfonyl)-1H-indo...)
Affinity DataIC50:  150nMpH: 7.5 T: 2°CAssay Description:Assays were performed in 96-well polystyrene round-bottomed plates in reaction buffer containing biotinylated substrate and purified kinase in the pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Gsk

LigandPNGBDBM28497((3R,5S)-5-[2-(4-{[(3-phenoxyphenyl)methyl]amino}th...)
Affinity DataIC50:  180nMpH: 7.5 T: 2°CAssay Description:Assays were performed in 96-well polystyrene round-bottomed plates in reaction buffer containing biotinylated substrate and purified kinase in the pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Gsk

LigandPNGBDBM28509((3R,5S)-5-[2-(4-{[1-(1,3-thiazol-4-ylmethyl)-1H-in...)
Affinity DataIC50:  180nMAssay Description:Assays were performed in 96-well polystyrene round-bottomed plates in reaction buffer containing biotinylated substrate and purified kinase in the pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Gsk

LigandPNGBDBM28496((3R,5S)-5-{2-[4-({3-chloro-4-[(6-fluoroquinolin-4-...)
Affinity DataIC50:  180nMAssay Description:Assays were performed in 96-well polystyrene round-bottomed plates in reaction buffer containing biotinylated substrate and purified kinase in the pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Gsk

LigandPNGBDBM28494((3R,5S)-5-[2-(4-{[3-chloro-4-(pyridin-2-yloxy)phen...)
Affinity DataIC50:  190nMpH: 7.5 T: 2°CAssay Description:Assays were performed in 96-well polystyrene round-bottomed plates in reaction buffer containing biotinylated substrate and purified kinase in the pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Gsk

LigandPNGBDBM28510((3R,5S)-5-(2-{4-[(1-benzyl-3-fluoro-1H-indol-5-yl)...)
Affinity DataIC50:  210nMAssay Description:Assays were performed in 96-well polystyrene round-bottomed plates in reaction buffer containing biotinylated substrate and purified kinase in the pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Gsk

LigandPNGBDBM28499((3R,5S)-5-[2-(4-{[4-(pyridin-2-ylsulfanyl)phenyl]a...)
Affinity DataIC50:  220nMAssay Description:Assays were performed in 96-well polystyrene round-bottomed plates in reaction buffer containing biotinylated substrate and purified kinase in the pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Gsk

LigandPNGBDBM28505((3R,5S)-5-{2-[4-({1-[(3-fluorobenzene)sulfonyl]-1H...)
Affinity DataIC50:  230nMpH: 7.5 T: 2°CAssay Description:Assays were performed in 96-well polystyrene round-bottomed plates in reaction buffer containing biotinylated substrate and purified kinase in the pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Gsk

LigandPNGBDBM28510((3R,5S)-5-(2-{4-[(1-benzyl-3-fluoro-1H-indol-5-yl)...)
Affinity DataIC50:  240nMpH: 7.5 T: 2°CAssay Description:Assays were performed in 96-well polystyrene round-bottomed plates in reaction buffer containing biotinylated substrate and purified kinase in the pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Gsk

LigandPNGBDBM28498((3R,5S)-5-(2-{4-[(4-benzylphenyl)amino]thieno[3,2-...)
Affinity DataIC50:  240nMpH: 7.5 T: 2°CAssay Description:Assays were performed in 96-well polystyrene round-bottomed plates in reaction buffer containing biotinylated substrate and purified kinase in the pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Gsk

LigandPNGBDBM28493((3R,5S)-5-[2-(4-{[5-(pyridin-2-yloxy)naphthalen-2-...)
Affinity DataIC50:  260nMAssay Description:Assays were performed in 96-well polystyrene round-bottomed plates in reaction buffer containing biotinylated substrate and purified kinase in the pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Gsk

LigandPNGBDBM28496((3R,5S)-5-{2-[4-({3-chloro-4-[(6-fluoroquinolin-4-...)
Affinity DataIC50:  280nMpH: 7.5 T: 2°CAssay Description:Assays were performed in 96-well polystyrene round-bottomed plates in reaction buffer containing biotinylated substrate and purified kinase in the pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Gsk

LigandPNGBDBM28495((3R,5S)-5-{2-[4-({3-chloro-4-[(5-methyl-1,2-oxazol...)
Affinity DataIC50:  370nMAssay Description:Assays were performed in 96-well polystyrene round-bottomed plates in reaction buffer containing biotinylated substrate and purified kinase in the pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Gsk

LigandPNGBDBM28495((3R,5S)-5-{2-[4-({3-chloro-4-[(5-methyl-1,2-oxazol...)
Affinity DataIC50:  400nMpH: 7.5 T: 2°CAssay Description:Assays were performed in 96-well polystyrene round-bottomed plates in reaction buffer containing biotinylated substrate and purified kinase in the pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Gsk

LigandPNGBDBM28492((3R,5S)-5-{2-[4-({6-[(3-fluorophenyl)methoxy]pyrid...)
Affinity DataIC50:  450nMAssay Description:Assays were performed in 96-well polystyrene round-bottomed plates in reaction buffer containing biotinylated substrate and purified kinase in the pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Gsk

LigandPNGBDBM28500((3R,5S)-5-{2-[4-({3-chloro-4-[(3-fluorophenyl)sulf...)
Affinity DataIC50:  630nMpH: 7.5 T: 2°CAssay Description:Assays were performed in 96-well polystyrene round-bottomed plates in reaction buffer containing biotinylated substrate and purified kinase in the pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Gsk

LigandPNGBDBM28509((3R,5S)-5-[2-(4-{[1-(1,3-thiazol-4-ylmethyl)-1H-in...)
Affinity DataIC50:  680nMpH: 7.5 T: 2°CAssay Description:Assays were performed in 96-well polystyrene round-bottomed plates in reaction buffer containing biotinylated substrate and purified kinase in the pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Gsk

LigandPNGBDBM28500((3R,5S)-5-{2-[4-({3-chloro-4-[(3-fluorophenyl)sulf...)
Affinity DataIC50:  800nMAssay Description:Assays were performed in 96-well polystyrene round-bottomed plates in reaction buffer containing biotinylated substrate and purified kinase in the pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Gsk

LigandPNGBDBM28493((3R,5S)-5-[2-(4-{[5-(pyridin-2-yloxy)naphthalen-2-...)
Affinity DataIC50:  1.05E+3nMpH: 7.5 T: 2°CAssay Description:Assays were performed in 96-well polystyrene round-bottomed plates in reaction buffer containing biotinylated substrate and purified kinase in the pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Gsk

LigandPNGBDBM28499((3R,5S)-5-[2-(4-{[4-(pyridin-2-ylsulfanyl)phenyl]a...)
Affinity DataIC50:  1.65E+3nMpH: 7.5 T: 2°CAssay Description:Assays were performed in 96-well polystyrene round-bottomed plates in reaction buffer containing biotinylated substrate and purified kinase in the pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Gsk

LigandPNGBDBM28492((3R,5S)-5-{2-[4-({6-[(3-fluorophenyl)methoxy]pyrid...)
Affinity DataIC50:  2.60E+3nMpH: 7.5 T: 2°CAssay Description:Assays were performed in 96-well polystyrene round-bottomed plates in reaction buffer containing biotinylated substrate and purified kinase in the pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Gsk

LigandPNGBDBM28508((3R,5S)-5-[2-(4-{[1-(2-phenylethyl)-1H-indol-5-yl]...)
Affinity DataIC50:  2.66E+3nMAssay Description:Assays were performed in 96-well polystyrene round-bottomed plates in reaction buffer containing biotinylated substrate and purified kinase in the pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Gsk

LigandPNGBDBM28508((3R,5S)-5-[2-(4-{[1-(2-phenylethyl)-1H-indol-5-yl]...)
Affinity DataIC50:  3.16E+3nMpH: 7.5 T: 2°CAssay Description:Assays were performed in 96-well polystyrene round-bottomed plates in reaction buffer containing biotinylated substrate and purified kinase in the pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed