Compile Data Set for Download or QSAR
maximum 50k data
Found 81 Enz. Inhib. hit(s) with all data for entry = 50028392
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50257624(7-(phenylsulfonyl)-2,3,4,5-tetrahydro-1H-benzo[d]a...)
Affinity DataKi:  6nMAssay Description:Displacement of [3H]mesulergine form human recombinant 5HT2C receptor expressed in mouse Swiss 3T3 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50257613(CHEMBL493951 | N-(cyclopropylmethyl)-N-methyl-2,3,...)
Affinity DataKi:  7nMAssay Description:Displacement of [3H]mesulergine form human recombinant 5HT2C receptor expressed in mouse Swiss 3T3 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50257615(7-(piperidin-1-ylsulfonyl)-2,3,4,5-tetrahydro-1H-b...)
Affinity DataKi:  9nMAssay Description:Displacement of [3H]mesulergine form human recombinant 5HT2C receptor expressed in mouse Swiss 3T3 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50257612(CHEMBL493950 | N-benzyl-N-methyl-2,3,4,5-tetrahydr...)
Affinity DataKi:  10nMAssay Description:Displacement of [3H]mesulergine form human recombinant 5HT2C receptor expressed in mouse Swiss 3T3 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50257621(7-(4-(2-chlorophenoxy)piperidin-1-ylsulfonyl)-2,3,...)
Affinity DataKi:  13nMAssay Description:Displacement of [3H]mesulergine form human recombinant 5HT2C receptor expressed in mouse Swiss 3T3 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50257620(7-(4-(2-fluorophenoxy)piperidin-1-ylsulfonyl)-2,3,...)
Affinity DataKi:  15nMAssay Description:Displacement of [3H]mesulergine form human recombinant 5HT2C receptor expressed in mouse Swiss 3T3 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50257563(CHEMBL492349 | N-(2-chlorobenzyl)-2,3,4,5-tetrahyd...)
Affinity DataKi:  30nMAssay Description:Displacement of [3H]mesulergine form human recombinant 5HT2C receptor expressed in mouse Swiss 3T3 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50257614(7-(pyrrolidin-1-ylsulfonyl)-2,3,4,5-tetrahydro-1H-...)
Affinity DataKi:  51nMAssay Description:Displacement of [3H]mesulergine form human recombinant 5HT2C receptor expressed in mouse Swiss 3T3 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50257617(CHEMBL492556 | N-((2,3-dihydrobenzofuran-3-yl)meth...)
Affinity DataKi:  58nMAssay Description:Displacement of [3H]mesulergine form human recombinant 5HT2C receptor expressed in mouse Swiss 3T3 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50257565(CHEMBL492949 | N,N-dimethyl-2,3,4,5-tetrahydro-1H-...)
Affinity DataKi:  87nMAssay Description:Displacement of [3H]mesulergine form human recombinant 5HT2C receptor expressed in mouse Swiss 3T3 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50257611(CHEMBL522349 | N-(2-fluorophenyl)-2,3,4,5-tetrahyd...)
Affinity DataKi:  133nMAssay Description:Displacement of [3H]mesulergine form human recombinant 5HT2C receptor expressed in mouse Swiss 3T3 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50257562(CHEMBL492348 | N-(2-chlorophenyl)-2,3,4,5-tetrahyd...)
Affinity DataKi:  156nMAssay Description:Displacement of [3H]mesulergine form human recombinant 5HT2C receptor expressed in mouse Swiss 3T3 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50257616(4-(2,3,4,5-tetrahydro-1H-benzo[d]azepin-7-ylsulfon...)
Affinity DataKi:  196nMAssay Description:Displacement of [3H]mesulergine form human recombinant 5HT2C receptor expressed in mouse Swiss 3T3 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50257564(CHEMBL511044 | N-(cyclopropylmethyl)-2,3,4,5-tetra...)
Affinity DataKi:  235nMAssay Description:Displacement of [3H]mesulergine form human recombinant 5HT2C receptor expressed in mouse Swiss 3T3 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50257610(CHEMBL493152 | N-phenyl-2,3,4,5-tetrahydro-1H-benz...)
Affinity DataKi:  382nMAssay Description:Displacement of [3H]mesulergine form human recombinant 5HT2C receptor expressed in mouse Swiss 3T3 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50257609(CHEMBL493151 | N-propyl-2,3,4,5-tetrahydro-1H-benz...)
Affinity DataKi:  531nMAssay Description:Displacement of [3H]mesulergine form human recombinant 5HT2C receptor expressed in mouse Swiss 3T3 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50257566(CHEMBL492950 | N-methyl-N-phenyl-2,3,4,5-tetrahydr...)
Affinity DataKi:  1.20E+3nMAssay Description:Displacement of [3H]mesulergine form human recombinant 5HT2C receptor expressed in mouse Swiss 3T3 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50257570(7-(3-(4-chlorophenoxy)azetidin-1-ylsulfonyl)-2,3,4...)
Affinity DataKi:  2.09E+3nMAssay Description:Binding affinity to human ERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50257621(7-(4-(2-chlorophenoxy)piperidin-1-ylsulfonyl)-2,3,...)
Affinity DataKi:  2.90E+3nMAssay Description:Binding affinity to human ERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50257617(CHEMBL492556 | N-((2,3-dihydrobenzofuran-3-yl)meth...)
Affinity DataKi:  2.99E+3nMAssay Description:Binding affinity to human ERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50257568(7-(3-(2-chlorophenoxy)azetidin-1-ylsulfonyl)-2,3,4...)
Affinity DataKi:  3.41E+3nMAssay Description:Binding affinity to human ERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50257571((R)-7-(3-(2-chlorophenoxy)pyrrolidin-1-ylsulfonyl)...)
Affinity DataKi:  3.43E+3nMAssay Description:Binding affinity to human ERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50257569(7-(3-(3-chlorophenoxy)azetidin-1-ylsulfonyl)-2,3,4...)
Affinity DataKi:  3.69E+3nMAssay Description:Binding affinity to human ERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50257618((S)-7-(3-(2-chlorophenoxy)pyrrolidin-1-ylsulfonyl)...)
Affinity DataKi:  5.24E+3nMAssay Description:Binding affinity to human ERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50257624(7-(phenylsulfonyl)-2,3,4,5-tetrahydro-1H-benzo[d]a...)
Affinity DataKi: >7.20E+3nMAssay Description:Binding affinity to human ERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50257621(7-(4-(2-chlorophenoxy)piperidin-1-ylsulfonyl)-2,3,...)
Affinity DataEC50:  32nMAssay Description:Agonist activity at human 5HT2A receptor expressed in mouse Swiss 3T3 cells by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50257625(7-(2-fluorophenylsulfonyl)-2,3,4,5-tetrahydro-1H-b...)
Affinity DataEC50:  7nMAssay Description:Agonist activity at human recombinant 5HT2C receptor expressed in CHOK1 cells assessed as calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50257624(7-(phenylsulfonyl)-2,3,4,5-tetrahydro-1H-benzo[d]a...)
Affinity DataEC50:  9nMAssay Description:Agonist activity at human recombinant 5HT2C receptor expressed in CHOK1 cells assessed as calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50257626(7-(3-fluorophenylsulfonyl)-2,3,4,5-tetrahydro-1H-b...)
Affinity DataEC50:  9nMAssay Description:Agonist activity at human recombinant 5HT2C receptor expressed in CHOK1 cells assessed as calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50257569(7-(3-(3-chlorophenoxy)azetidin-1-ylsulfonyl)-2,3,4...)
Affinity DataEC50:  12nMAssay Description:Agonist activity at human recombinant 5HT2C receptor expressed in CHOK1 cells assessed as calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50257571((R)-7-(3-(2-chlorophenoxy)pyrrolidin-1-ylsulfonyl)...)
Affinity DataEC50:  14nMAssay Description:Agonist activity at human recombinant 5HT2C receptor expressed in CHOK1 cells assessed as calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50257627(7-(4-fluorophenylsulfonyl)-2,3,4,5-tetrahydro-1H-b...)
Affinity DataEC50:  15nMAssay Description:Agonist activity at human recombinant 5HT2B receptor by cell-based systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50257613(CHEMBL493951 | N-(cyclopropylmethyl)-N-methyl-2,3,...)
Affinity DataEC50:  17nMAssay Description:Agonist activity at human recombinant 5HT2B receptor by cell-based systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50257624(7-(phenylsulfonyl)-2,3,4,5-tetrahydro-1H-benzo[d]a...)
Affinity DataEC50:  18nMAssay Description:Agonist activity at human recombinant 5HT2B receptor by cell-based systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50257625(7-(2-fluorophenylsulfonyl)-2,3,4,5-tetrahydro-1H-b...)
Affinity DataEC50:  18nMAssay Description:Agonist activity at human recombinant 5HT2B receptor by cell-based systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50257570(7-(3-(4-chlorophenoxy)azetidin-1-ylsulfonyl)-2,3,4...)
Affinity DataEC50:  28nMAssay Description:Agonist activity at human recombinant 5HT2C receptor expressed in CHOK1 cells assessed as calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50257568(7-(3-(2-chlorophenoxy)azetidin-1-ylsulfonyl)-2,3,4...)
Affinity DataEC50:  31nMAssay Description:Agonist activity at human recombinant 5HT2C receptor expressed in CHOK1 cells assessed as calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50257618((S)-7-(3-(2-chlorophenoxy)pyrrolidin-1-ylsulfonyl)...)
Affinity DataEC50:  31nMAssay Description:Agonist activity at human recombinant 5HT2C receptor expressed in CHOK1 cells assessed as calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50257621(7-(4-(2-chlorophenoxy)piperidin-1-ylsulfonyl)-2,3,...)
Affinity DataEC50:  31nMAssay Description:Agonist activity at human recombinant 5HT2C receptor expressed in CHOK1 cells assessed as calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50257626(7-(3-fluorophenylsulfonyl)-2,3,4,5-tetrahydro-1H-b...)
Affinity DataEC50:  33nMAssay Description:Agonist activity at human recombinant 5HT2B receptor by cell-based systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50257615(7-(piperidin-1-ylsulfonyl)-2,3,4,5-tetrahydro-1H-b...)
Affinity DataEC50:  34nMAssay Description:Agonist activity at human recombinant 5HT2B receptor by cell-based systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50257617(CHEMBL492556 | N-((2,3-dihydrobenzofuran-3-yl)meth...)
Affinity DataEC50:  41nMAssay Description:Agonist activity at human recombinant 5HT2C receptor expressed in CHOK1 cells assessed as calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50257563(CHEMBL492349 | N-(2-chlorobenzyl)-2,3,4,5-tetrahyd...)
Affinity DataEC50:  46nMAssay Description:Agonist activity at human recombinant 5HT2C receptor expressed in CHOK1 cells assessed as calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50257565(CHEMBL492949 | N,N-dimethyl-2,3,4,5-tetrahydro-1H-...)
Affinity DataEC50:  47nMAssay Description:Agonist activity at human recombinant 5HT2C receptor expressed in CHOK1 cells assessed as calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50257614(7-(pyrrolidin-1-ylsulfonyl)-2,3,4,5-tetrahydro-1H-...)
Affinity DataEC50:  50nMAssay Description:Agonist activity at human recombinant 5HT2C receptor expressed in CHOK1 cells assessed as calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50257610(CHEMBL493152 | N-phenyl-2,3,4,5-tetrahydro-1H-benz...)
Affinity DataEC50:  69nMAssay Description:Agonist activity at human recombinant 5HT2B receptor by cell-based systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50257613(CHEMBL493951 | N-(cyclopropylmethyl)-N-methyl-2,3,...)
Affinity DataEC50:  71nMAssay Description:Agonist activity at human recombinant 5HT2C receptor expressed in CHOK1 cells assessed as calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50257611(CHEMBL522349 | N-(2-fluorophenyl)-2,3,4,5-tetrahyd...)
Affinity DataEC50:  75nMAssay Description:Agonist activity at human recombinant 5HT2B receptor by cell-based systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50257627(7-(4-fluorophenylsulfonyl)-2,3,4,5-tetrahydro-1H-b...)
Affinity DataEC50:  80nMAssay Description:Agonist activity at human recombinant 5HT2C receptor expressed in CHOK1 cells assessed as calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50257615(7-(piperidin-1-ylsulfonyl)-2,3,4,5-tetrahydro-1H-b...)
Affinity DataEC50:  84nMAssay Description:Agonist activity at human recombinant 5HT2C receptor expressed in CHOK1 cells assessed as calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Displayed 1 to 50 (of 81 total ) | Next | Last >>
Jump to: