Compile Data Set for Download or QSAR
Report error Found 104 Enz. Inhib. hit(s) with all data for entry = 3226
TargetCaspase-3(Human)
Washington University

LigandPNGBDBM10246((4S)-4-{[(1S)-1-{[(2S)-1-carboxy-3-oxopropan-2-yl]...)
Affinity DataIC50: 2.20nMAssay Description:The caspase enzymatic activity was determined by measuring the accumulation of a fluorogenic product. All assays were prepared in 96-well format. Rec...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2009
Entry Details Article
PubMed
TargetCaspase-7(Human)
Washington University

LigandPNGBDBM10246((4S)-4-{[(1S)-1-{[(2S)-1-carboxy-3-oxopropan-2-yl]...)
Affinity DataIC50: 2.95nMAssay Description:The caspase enzymatic activity was determined by measuring the accumulation of a fluorogenic product. All assays were prepared in 96-well format. Rec...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2009
Entry Details Article
PubMed
TargetCaspase-8(Human)
Washington University

LigandPNGBDBM10357((4S)-4-{[(1S)-1-{[(2S)-1-carboxy-3-oxopropan-2-yl]...)
Affinity DataIC50: 4.20nMAssay Description:The caspase enzymatic activity was determined by measuring the accumulation of a fluorogenic product. All assays were prepared in 96-well format. Rec...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2009
Entry Details Article
PubMed
TargetCaspase-6(Human)
Washington University

LigandPNGBDBM10356((4S)-4-{[(1S)-1-{[(2S)-1-carboxy-3-oxopropan-2-yl]...)
Affinity DataIC50: 8nMAssay Description:The caspase enzymatic activity was determined by measuring the accumulation of a fluorogenic product. All assays were prepared in 96-well format. Rec...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2009
Entry Details Article
PubMed
TargetCaspase-1(Human)
Washington University

LigandPNGBDBM10355(CHEMBL37630 | (3S)-3-[(2S)-2-[(2S)-2-[(2S)-2-aceta...)
Affinity DataIC50: 8.40nMpH: 7.4 T: 2°CAssay Description:The caspase enzymatic activity was determined by measuring the accumulation of a fluorogenic product. All assays were prepared in 96-well format. Rec...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2009
Entry Details Article
PubMed
TargetCaspase-3(Human)
Washington University

LigandPNGBDBM10323(JMC522188 Compound 2 | IST-3 | CHEMBL439753 | 1-be...)
Affinity DataIC50: 14.5nMAssay Description:The caspase enzymatic activity was determined by measuring the accumulation of a fluorogenic product. All assays were prepared in 96-well format. Rec...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2009
Entry Details Article
PubMed
TargetCaspase-3(Human)
Washington University

LigandPNGBDBM29588(CHEMBL226779 | isatin Michael acceptor (IMA) analo...)
Affinity DataIC50: 27.8nMAssay Description:The caspase enzymatic activity was determined by measuring the accumulation of a fluorogenic product. All assays were prepared in 96-well format. Rec...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2009
Entry Details Article
PubMed
TargetCaspase-3(Human)
Washington University

LigandPNGBDBM29581(isatin sulfonamide, 16a)
Affinity DataIC50: 114nMAssay Description:The caspase enzymatic activity was determined by measuring the accumulation of a fluorogenic product. All assays were prepared in 96-well format. Rec...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2009
Entry Details Article
PubMed
TargetCaspase-7(Human)
Washington University

LigandPNGBDBM29581(isatin sulfonamide, 16a)
Affinity DataIC50: 132nMAssay Description:The caspase enzymatic activity was determined by measuring the accumulation of a fluorogenic product. All assays were prepared in 96-well format. Rec...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2009
Entry Details Article
PubMed
TargetCaspase-6(Human)
Washington University

LigandPNGBDBM29578(isatin Michael acceptor (IMA) analogue, 13a)
Affinity DataIC50: 151nMAssay Description:The caspase enzymatic activity was determined by measuring the accumulation of a fluorogenic product. All assays were prepared in 96-well format. Rec...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2009
Entry Details Article
PubMed
TargetCaspase-6(Human)
Washington University

LigandPNGBDBM29582(isatin Michael acceptor (IMA) analogue, 18a)
Affinity DataIC50: 156nMAssay Description:The caspase enzymatic activity was determined by measuring the accumulation of a fluorogenic product. All assays were prepared in 96-well format. Rec...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2009
Entry Details Article
PubMed
TargetCaspase-6(Human)
Washington University

LigandPNGBDBM29579(isatin Michael acceptor (IMA) analogue, 13b)
Affinity DataIC50: 188nMAssay Description:The caspase enzymatic activity was determined by measuring the accumulation of a fluorogenic product. All assays were prepared in 96-well format. Rec...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2009
Entry Details Article
PubMed
TargetCaspase-6(Human)
Washington University

LigandPNGBDBM29583(isatin Michael acceptor (IMA) analogue, 18b)
Affinity DataIC50: 197nMAssay Description:The caspase enzymatic activity was determined by measuring the accumulation of a fluorogenic product. All assays were prepared in 96-well format. Rec...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2009
Entry Details Article
PubMed
TargetCaspase-6(Human)
Washington University

LigandPNGBDBM29580(isatin Michael acceptor (IMA) analogue, 13c)
Affinity DataIC50: 230nMAssay Description:The caspase enzymatic activity was determined by measuring the accumulation of a fluorogenic product. All assays were prepared in 96-well format. Rec...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2009
Entry Details Article
PubMed
TargetCaspase-6(Human)
Washington University

LigandPNGBDBM29585(isatin Michael acceptor (IMA) analogue, 19a)
Affinity DataIC50: 241nMAssay Description:The caspase enzymatic activity was determined by measuring the accumulation of a fluorogenic product. All assays were prepared in 96-well format. Rec...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2009
Entry Details Article
PubMed
TargetCaspase-7(Human)
Washington University

LigandPNGBDBM29582(isatin Michael acceptor (IMA) analogue, 18a)
Affinity DataIC50: 248nMAssay Description:The caspase enzymatic activity was determined by measuring the accumulation of a fluorogenic product. All assays were prepared in 96-well format. Rec...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2009
Entry Details Article
PubMed
TargetCaspase-6(Human)
Washington University

LigandPNGBDBM29584(isatin Michael acceptor (IMA) analogue, 18c)
Affinity DataIC50: 280nMAssay Description:The caspase enzymatic activity was determined by measuring the accumulation of a fluorogenic product. All assays were prepared in 96-well format. Rec...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2009
Entry Details Article
PubMed
TargetCaspase-3(Human)
Washington University

LigandPNGBDBM29582(isatin Michael acceptor (IMA) analogue, 18a)
Affinity DataIC50: 323nMAssay Description:The caspase enzymatic activity was determined by measuring the accumulation of a fluorogenic product. All assays were prepared in 96-well format. Rec...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2009
Entry Details Article
PubMed
TargetCaspase-6(Human)
Washington University

LigandPNGBDBM29572(isatin Michael acceptor (IMA) analogue, 11a)
Affinity DataIC50: 325nMAssay Description:The caspase enzymatic activity was determined by measuring the accumulation of a fluorogenic product. All assays were prepared in 96-well format. Rec...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2009
Entry Details Article
PubMed
TargetCaspase-7(Human)
Washington University

LigandPNGBDBM29584(isatin Michael acceptor (IMA) analogue, 18c)
Affinity DataIC50: 340nMAssay Description:The caspase enzymatic activity was determined by measuring the accumulation of a fluorogenic product. All assays were prepared in 96-well format. Rec...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2009
Entry Details Article
PubMed
TargetCaspase-6(Human)
Washington University

LigandPNGBDBM29586(isatin Michael acceptor (IMA) analogue, 19b)
Affinity DataIC50: 358nMAssay Description:The caspase enzymatic activity was determined by measuring the accumulation of a fluorogenic product. All assays were prepared in 96-well format. Rec...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2009
Entry Details Article
PubMed
TargetCaspase-3(Human)
Washington University

LigandPNGBDBM29584(isatin Michael acceptor (IMA) analogue, 18c)
Affinity DataIC50: 365nMAssay Description:The caspase enzymatic activity was determined by measuring the accumulation of a fluorogenic product. All assays were prepared in 96-well format. Rec...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2009
Entry Details Article
PubMed
TargetCaspase-6(Human)
Washington University

LigandPNGBDBM29575(isatin Michael acceptor (IMA) analogue, 12a)
Affinity DataIC50: 425nMAssay Description:The caspase enzymatic activity was determined by measuring the accumulation of a fluorogenic product. All assays were prepared in 96-well format. Rec...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2009
Entry Details Article
PubMed
TargetCaspase-7(Human)
Washington University

LigandPNGBDBM29586(isatin Michael acceptor (IMA) analogue, 19b)
Affinity DataIC50: 443nMAssay Description:The caspase enzymatic activity was determined by measuring the accumulation of a fluorogenic product. All assays were prepared in 96-well format. Rec...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2009
Entry Details Article
PubMed
TargetCaspase-6(Human)
Washington University

LigandPNGBDBM29576(isatin Michael acceptor (IMA) analogue, 12b)
Affinity DataIC50: 453nMAssay Description:The caspase enzymatic activity was determined by measuring the accumulation of a fluorogenic product. All assays were prepared in 96-well format. Rec...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2009
Entry Details Article
PubMed
TargetCaspase-6(Human)
Washington University

LigandPNGBDBM29587(isatin Michael acceptor (IMA) analogue, 19c)
Affinity DataIC50: 468nMAssay Description:The caspase enzymatic activity was determined by measuring the accumulation of a fluorogenic product. All assays were prepared in 96-well format. Rec...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2009
Entry Details Article
PubMed
TargetCaspase-7(Human)
Washington University

LigandPNGBDBM29583(isatin Michael acceptor (IMA) analogue, 18b)
Affinity DataIC50: 471nMAssay Description:The caspase enzymatic activity was determined by measuring the accumulation of a fluorogenic product. All assays were prepared in 96-well format. Rec...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2009
Entry Details Article
PubMed
TargetCaspase-7(Human)
Washington University

LigandPNGBDBM29587(isatin Michael acceptor (IMA) analogue, 19c)
Affinity DataIC50: 471nMAssay Description:The caspase enzymatic activity was determined by measuring the accumulation of a fluorogenic product. All assays were prepared in 96-well format. Rec...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2009
Entry Details Article
PubMed
TargetCaspase-3(Human)
Washington University

LigandPNGBDBM29574(isatin Michael acceptor (IMA) analogue, 11c)
Affinity DataIC50: 529nMAssay Description:The caspase enzymatic activity was determined by measuring the accumulation of a fluorogenic product. All assays were prepared in 96-well format. Rec...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2009
Entry Details Article
PubMed
TargetCaspase-6(Human)
Washington University

LigandPNGBDBM29573(isatin Michael acceptor (IMA) analogue, 11b)
Affinity DataIC50: 545nMAssay Description:The caspase enzymatic activity was determined by measuring the accumulation of a fluorogenic product. All assays were prepared in 96-well format. Rec...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2009
Entry Details Article
PubMed
TargetCaspase-6(Human)
Washington University

LigandPNGBDBM29574(isatin Michael acceptor (IMA) analogue, 11c)
Affinity DataIC50: 568nMAssay Description:The caspase enzymatic activity was determined by measuring the accumulation of a fluorogenic product. All assays were prepared in 96-well format. Rec...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2009
Entry Details Article
PubMed
TargetCaspase-3(Human)
Washington University

LigandPNGBDBM29572(isatin Michael acceptor (IMA) analogue, 11a)
Affinity DataIC50: 583nMAssay Description:The caspase enzymatic activity was determined by measuring the accumulation of a fluorogenic product. All assays were prepared in 96-well format. Rec...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2009
Entry Details Article
PubMed
TargetCaspase-7(Human)
Washington University

LigandPNGBDBM29585(isatin Michael acceptor (IMA) analogue, 19a)
Affinity DataIC50: 587nMAssay Description:The caspase enzymatic activity was determined by measuring the accumulation of a fluorogenic product. All assays were prepared in 96-well format. Rec...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2009
Entry Details Article
PubMed
TargetCaspase-6(Human)
Washington University

LigandPNGBDBM29577(isatin Michael acceptor (IMA) analogue, 12c)
Affinity DataIC50: 592nMAssay Description:The caspase enzymatic activity was determined by measuring the accumulation of a fluorogenic product. All assays were prepared in 96-well format. Rec...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2009
Entry Details Article
PubMed
TargetCaspase-3(Human)
Washington University

LigandPNGBDBM29585(isatin Michael acceptor (IMA) analogue, 19a)
Affinity DataIC50: 671nMAssay Description:The caspase enzymatic activity was determined by measuring the accumulation of a fluorogenic product. All assays were prepared in 96-well format. Rec...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2009
Entry Details Article
PubMed
TargetCaspase-3(Human)
Washington University

LigandPNGBDBM29586(isatin Michael acceptor (IMA) analogue, 19b)
Affinity DataIC50: 673nMAssay Description:The caspase enzymatic activity was determined by measuring the accumulation of a fluorogenic product. All assays were prepared in 96-well format. Rec...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2009
Entry Details Article
PubMed
TargetCaspase-3(Human)
Washington University

LigandPNGBDBM29583(isatin Michael acceptor (IMA) analogue, 18b)
Affinity DataIC50: 718nMAssay Description:The caspase enzymatic activity was determined by measuring the accumulation of a fluorogenic product. All assays were prepared in 96-well format. Rec...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2009
Entry Details Article
PubMed
TargetCaspase-3(Human)
Washington University

LigandPNGBDBM29587(isatin Michael acceptor (IMA) analogue, 19c)
Affinity DataIC50: 724nMAssay Description:The caspase enzymatic activity was determined by measuring the accumulation of a fluorogenic product. All assays were prepared in 96-well format. Rec...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2009
Entry Details Article
PubMed
TargetCaspase-7(Human)
Washington University

LigandPNGBDBM29572(isatin Michael acceptor (IMA) analogue, 11a)
Affinity DataIC50: 878nMAssay Description:The caspase enzymatic activity was determined by measuring the accumulation of a fluorogenic product. All assays were prepared in 96-well format. Rec...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2009
Entry Details Article
PubMed
TargetCaspase-6(Human)
Washington University

LigandPNGBDBM29588(CHEMBL226779 | isatin Michael acceptor (IMA) analo...)
Affinity DataIC50: 918nMAssay Description:The caspase enzymatic activity was determined by measuring the accumulation of a fluorogenic product. All assays were prepared in 96-well format. Rec...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2009
Entry Details Article
PubMed
TargetCaspase-3(Human)
Washington University

LigandPNGBDBM29571(isatin sulfonamide, 10a)
Affinity DataIC50: 1.03E+3nMAssay Description:The caspase enzymatic activity was determined by measuring the accumulation of a fluorogenic product. All assays were prepared in 96-well format. Rec...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2009
Entry Details Article
PubMed
TargetCaspase-7(Human)
Washington University

LigandPNGBDBM29573(isatin Michael acceptor (IMA) analogue, 11b)
Affinity DataIC50: 1.15E+3nMAssay Description:The caspase enzymatic activity was determined by measuring the accumulation of a fluorogenic product. All assays were prepared in 96-well format. Rec...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2009
Entry Details Article
PubMed
TargetCaspase-3(Human)
Washington University

LigandPNGBDBM29573(isatin Michael acceptor (IMA) analogue, 11b)
Affinity DataIC50: 1.41E+3nMAssay Description:The caspase enzymatic activity was determined by measuring the accumulation of a fluorogenic product. All assays were prepared in 96-well format. Rec...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2009
Entry Details Article
PubMed
TargetCaspase-3(Human)
Washington University

LigandPNGBDBM29570(isatin sulfonamide, 9c)
Affinity DataIC50: 1.43E+3nMAssay Description:The caspase enzymatic activity was determined by measuring the accumulation of a fluorogenic product. All assays were prepared in 96-well format. Rec...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2009
Entry Details Article
PubMed
TargetCaspase-3(Human)
Washington University

LigandPNGBDBM29578(isatin Michael acceptor (IMA) analogue, 13a)
Affinity DataIC50: 1.45E+3nMAssay Description:The caspase enzymatic activity was determined by measuring the accumulation of a fluorogenic product. All assays were prepared in 96-well format. Rec...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2009
Entry Details Article
PubMed
TargetCaspase-7(Human)
Washington University

LigandPNGBDBM29571(isatin sulfonamide, 10a)
Affinity DataIC50: 1.48E+3nMAssay Description:The caspase enzymatic activity was determined by measuring the accumulation of a fluorogenic product. All assays were prepared in 96-well format. Rec...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2009
Entry Details Article
PubMed
TargetCaspase-3(Human)
Washington University

LigandPNGBDBM29577(isatin Michael acceptor (IMA) analogue, 12c)
Affinity DataIC50: 1.55E+3nMAssay Description:The caspase enzymatic activity was determined by measuring the accumulation of a fluorogenic product. All assays were prepared in 96-well format. Rec...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2009
Entry Details Article
PubMed
TargetCaspase-7(Human)
Washington University

LigandPNGBDBM29578(isatin Michael acceptor (IMA) analogue, 13a)
Affinity DataIC50: 1.63E+3nMAssay Description:The caspase enzymatic activity was determined by measuring the accumulation of a fluorogenic product. All assays were prepared in 96-well format. Rec...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2009
Entry Details Article
PubMed
TargetCaspase-3(Human)
Washington University

LigandPNGBDBM29579(isatin Michael acceptor (IMA) analogue, 13b)
Affinity DataIC50: 1.67E+3nMAssay Description:The caspase enzymatic activity was determined by measuring the accumulation of a fluorogenic product. All assays were prepared in 96-well format. Rec...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2009
Entry Details Article
PubMed
TargetCaspase-7(Human)
Washington University

LigandPNGBDBM29579(isatin Michael acceptor (IMA) analogue, 13b)
Affinity DataIC50: 1.89E+3nMAssay Description:The caspase enzymatic activity was determined by measuring the accumulation of a fluorogenic product. All assays were prepared in 96-well format. Rec...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2009
Entry Details Article
PubMed
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