Compile Data Set for Download or QSAR
Report error Found 25 Enz. Inhib. hit(s) with all data for entry = 50030335
TargetProkineticin receptor 1(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50294596(1-(2-(5-(4-chlorobenzyl)-1-(4-methoxybenzyl)-4,6-d...)
Affinity DataIC50: 19nMAssay Description:Antagonist activity at human PKR1 expressed in HEK293 cells assessed as inhibition of PK1-induced calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetProkineticin receptor 1(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50294589(1-(2-(1,5-bis(4-methoxybenzyl)-4,6-dioxo-1,4,5,6-t...)
Affinity DataIC50: 21nMAssay Description:Antagonist activity at human PKR1 expressed in HEK293 cells assessed as inhibition of PK1-induced calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetProkineticin receptor 1(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50294586(1-(2-(5-(3,4-dichlorobenzyl)-1-(4-methoxybenzyl)-4...)
Affinity DataIC50: 22nMAssay Description:Antagonist activity at human PKR1 expressed in HEK293 cells assessed as inhibition of PK1-induced calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetProkineticin receptor 1(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50294601(1-(2-(1-(4-hydroxybenzyl)-5-(4-methoxybenzyl)-4,6-...)
Affinity DataIC50: 27nMAssay Description:Antagonist activity at human PKR1 expressed in HEK293 cells assessed as inhibition of PK1-induced calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetProkineticin receptor 1(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50294585(1-(2-(5-(4-fluorobenzyl)-1-(4-methoxybenzyl)-4,6-d...)
Affinity DataIC50: 33nMAssay Description:Antagonist activity at human PKR1 expressed in HEK293 cells assessed as inhibition of PK1-induced calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetProkineticin receptor 1(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50294604(1-(2-(5-(3,4-dichlorobenzyl)-1-(4-(difluoromethoxy...)
Affinity DataIC50: 47nMAssay Description:Antagonist activity at human PKR1 expressed in HEK293 cells assessed as inhibition of PK1-induced calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetProkineticin receptor 1(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50294603(1-(2-(5-(4-methoxybenzyl)-1-((6-methoxypyridin-3-y...)
Affinity DataIC50: 51nMAssay Description:Antagonist activity at human PKR1 expressed in HEK293 cells assessed as inhibition of PK1-induced calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetProkineticin receptor 1(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50294592(1-(2-(5-(4-cyanobenzyl)-1-(4-methoxybenzyl)-4,6-di...)
Affinity DataIC50: 318nMAssay Description:Antagonist activity at human PKR1 expressed in HEK293 cells assessed as inhibition of PK1-induced calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetProkineticin receptor 1(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50294606(1-(2-(5-benzyl-1-(4-methoxybenzyl)-4,6-dioxo-1,4,5...)
Affinity DataIC50: 336nMAssay Description:Antagonist activity at human PKR1 expressed in HEK293 cells assessed as inhibition of PK1-induced calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetProkineticin receptor 1(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50294591(1-(2-(1-(4-methoxybenzyl)-5-(4-methoxyphenethyl)-4...)
Affinity DataIC50: 461nMAssay Description:Antagonist activity at human PKR1 expressed in HEK293 cells assessed as inhibition of PK1-induced calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetProkineticin receptor 1(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50294598(1-(2-(5-(3,4-dichlorobenzyl)-4,6-dioxo-1-(4-propox...)
Affinity DataIC50: 515nMAssay Description:Antagonist activity at human PKR1 expressed in HEK293 cells assessed as inhibition of PK1-induced calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetProkineticin receptor 1(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50294590(1-(2-(5-(4-hydroxybenzyl)-1-(4-methoxybenzyl)-4,6-...)
Affinity DataIC50: 1.16E+3nMAssay Description:Antagonist activity at human PKR1 expressed in HEK293 cells assessed as inhibition of PK1-induced calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetProkineticin receptor 1(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50294593(1-(3-(5-(3,4-dichlorobenzyl)-1-(4-methoxybenzyl)-4...)
Affinity DataIC50: 1.21E+3nMAssay Description:Antagonist activity at human PKR1 expressed in HEK293 cells assessed as inhibition of PK1-induced calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetProkineticin receptor 1(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50294602(1-(2-(5-(4-chlorobenzyl)-1-(furan-3-yl)-4,6-dioxo-...)
Affinity DataIC50: 1.87E+3nMAssay Description:Antagonist activity at human PKR1 expressed in HEK293 cells assessed as inhibition of PK1-induced calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetProkineticin receptor 1(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50294583(1-(2-(5-butyl-1-(4-methoxybenzyl)-4,6-dioxo-1,4,5,...)
Affinity DataIC50: 2.18E+3nMAssay Description:Antagonist activity at human PKR1 expressed in HEK293 cells assessed as inhibition of PK1-induced calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetProkineticin receptor 1(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50294607(1-(2-(1-(4-methoxybenzyl)-4,6-dioxo-5-phenethyl-1,...)
Affinity DataIC50: 2.50E+3nMAssay Description:Antagonist activity at human PKR1 expressed in HEK293 cells assessed as inhibition of PK1-induced calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetProkineticin receptor 1(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50294584(1-(2-(5-(furan-2-yl)-1-(4-methoxybenzyl)-4,6-dioxo...)
Affinity DataIC50: 2.59E+3nMAssay Description:Antagonist activity at human PKR1 expressed in HEK293 cells assessed as inhibition of PK1-induced calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetProkineticin receptor 1(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50294594(1-(2-(5-(4-fluorobenzyl)-1-(4-methoxyphenethyl)-4,...)
Affinity DataIC50: 2.86E+3nMAssay Description:Antagonist activity at human PKR1 expressed in HEK293 cells assessed as inhibition of PK1-induced calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetProkineticin receptor 1(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50294600(1-(2-(5-(4-methoxybenzyl)-1-((4-methoxycyclohexyl)...)
Affinity DataIC50: 3.26E+3nMAssay Description:Antagonist activity at human PKR1 expressed in HEK293 cells assessed as inhibition of PK1-induced calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetProkineticin receptor 1(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50294587(1-(2-(5-(3-methoxybenzyl)-1-(4-methoxybenzyl)-4,6-...)
Affinity DataIC50: 3.69E+3nMAssay Description:Antagonist activity at human PKR1 expressed in HEK293 cells assessed as inhibition of PK1-induced calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetProkineticin receptor 1(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50294595(1-(2-(1-benzyl-5-(4-chloro-2-methoxybenzyl)-4,6-di...)
Affinity DataIC50: 4.78E+3nMAssay Description:Antagonist activity at human PKR1 expressed in HEK293 cells assessed as inhibition of PK1-induced calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetProkineticin receptor 1(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50294599(1-(2-(5-(3,4-dichlorobenzyl)-1-hexyl-4,6-dioxo-1,4...)
Affinity DataIC50: 6.51E+3nMAssay Description:Antagonist activity at human PKR1 expressed in HEK293 cells assessed as inhibition of PK1-induced calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetProkineticin receptor 1(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50294588(1-(2-(5-(2-methoxybenzyl)-1-(4-methoxybenzyl)-4,6-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at human PKR1 expressed in HEK293 cells assessed as inhibition of PK1-induced calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetProkineticin receptor 1(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50294605(1-(2-(5-benzyl-1-(4-fluorobenzyl)-4,6-dioxo-1,4,5,...)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at human PKR1 expressed in HEK293 cells assessed as inhibition of PK1-induced calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetProkineticin receptor 1(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50294597(1-(2-(5-(4-fluorobenzyl)-1-(4-nitrobenzyl)-4,6-dio...)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at human PKR1 expressed in HEK293 cells assessed as inhibition of PK1-induced calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed