Compile Data Set for Download or QSAR
Report error Found 29 Enz. Inhib. hit(s) with all data for entry = 50030411
TargetHeat shock factor protein 1(Human)
Cytrx

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50295793BDBM50295793(N-(2-hydroxy-3-(piperidin-1-yl)propoxy)naphtho[1,2...)
Affinity DataEC50:  1.21E+4nMAssay Description:Transcriptional activation of HSF1 in heat shock stress-induced human HeLa cells assessed as granule formation treated 1 hr before heat shock challen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetHeat shock factor protein 1(Human)
Cytrx

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50295804BDBM50295804(N-(3-((cyclopropylmethyl)(isopropyl)amino)-2-hydro...)
Affinity DataEC50:  1.24E+4nMAssay Description:Transcriptional activation of HSF1 in heat shock stress-induced human HeLa cells assessed as granule formation treated 1 hr before heat shock challen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetHeat shock factor protein 1(Human)
Cytrx

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50295781BDBM50295781(N-(3-(tert-butyl(isopropyl)amino)-2-hydroxypropoxy...)
Affinity DataEC50:  1.66E+4nMAssay Description:Transcriptional activation of HSF1 in heat shock stress-induced human HeLa cells assessed as granule formation treated 1 hr before heat shock challen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetHeat shock factor protein 1(Human)
Cytrx

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50295788BDBM50295788(N-(3-(3,5-dimethylpiperidin-1-yl)-2-hydroxypropoxy...)
Affinity DataEC50:  1.74E+4nMAssay Description:Transcriptional activation of HSF1 in heat shock stress-induced human HeLa cells assessed as granule formation treated 1 hr before heat shock challen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetHeat shock factor protein 1(Human)
Cytrx

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50295800BDBM50295800(7-fluoro-N-(2-hydroxy-3-(piperidin-1-yl)propoxy)be...)
Affinity DataEC50:  1.85E+4nMAssay Description:Transcriptional activation of HSF1 in heat shock stress-induced human HeLa cells assessed as granule formation treated 1 hr before heat shock challen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetHeat shock factor protein 1(Human)
Cytrx

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50295801BDBM50295801(4-fluoro-N-(2-hydroxy-3-(piperidin-1-yl)propoxy)be...)
Affinity DataEC50:  2.02E+4nMAssay Description:Transcriptional activation of HSF1 in heat shock stress-induced human HeLa cells assessed as granule formation treated 1 hr before heat shock challen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetHeat shock factor protein 1(Human)
Cytrx

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50295797BDBM50295797(5-chloro-N-(2-hydroxy-3-(piperidin-1-yl)propoxy)be...)
Affinity DataEC50:  2.09E+4nMAssay Description:Transcriptional activation of HSF1 in heat shock stress-induced human HeLa cells assessed as granule formation treated 1 hr before heat shock challen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetHeat shock factor protein 1(Human)
Cytrx

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50295784BDBM50295784(N-(3-(dibutylamino)-2-hydroxypropoxy)benzo[d]oxazo...)
Affinity DataEC50:  2.09E+4nMAssay Description:Transcriptional activation of HSF1 in heat shock stress-induced human HeLa cells assessed as granule formation treated 1 hr before heat shock challen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetHeat shock factor protein 1(Human)
Cytrx

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50295805BDBM50295805(N-(3-((3-fluoropropyl)(isopropyl)amino)-2-hydroxyp...)
Affinity DataEC50:  2.28E+4nMAssay Description:Transcriptional activation of HSF1 in heat shock stress-induced human HeLa cells assessed as granule formation treated 1 hr before heat shock challen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetHeat shock factor protein 1(Human)
Cytrx

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50295796BDBM50295796(6-chloro-N-(2-hydroxy-3-(piperidin-1-yl)propoxy)be...)
Affinity DataEC50:  2.29E+4nMAssay Description:Transcriptional activation of HSF1 in heat shock stress-induced human HeLa cells assessed as granule formation treated 1 hr before heat shock challen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetHeat shock factor protein 1(Human)
Cytrx

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50295783BDBM50295783(N-(3-(ethyl(propyl)amino)-2-hydroxypropoxy)benzo[d...)
Affinity DataEC50:  2.30E+4nMAssay Description:Transcriptional activation of HSF1 in heat shock stress-induced human HeLa cells assessed as granule formation treated 1 hr before heat shock challen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetHeat shock factor protein 1(Human)
Cytrx

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50295785BDBM50295785(N-(3-(dipropylamino)-2-hydroxypropoxy)benzo[d]oxaz...)
Affinity DataEC50:  2.39E+4nMAssay Description:Transcriptional activation of HSF1 in heat shock stress-induced human HeLa cells assessed as granule formation treated 1 hr before heat shock challen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetHeat shock factor protein 1(Human)
Cytrx

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50295807BDBM50295807((S)-N-(2-hydroxy-3-(isopropyl(propyl)amino)propoxy...)
Affinity DataEC50:  2.41E+4nMAssay Description:Transcriptional activation of HSF1 in heat shock stress-induced human HeLa cells assessed as granule formation treated 1 hr before heat shock challen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetHeat shock factor protein 1(Human)
Cytrx

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50295782BDBM50295782(N-(3-(diisopropylamino)-2-hydroxypropoxy)benzo[d]o...)
Affinity DataEC50:  2.55E+4nMAssay Description:Transcriptional activation of HSF1 in heat shock stress-induced human HeLa cells assessed as granule formation treated 1 hr before heat shock challen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetHeat shock factor protein 1(Human)
Cytrx

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50295786BDBM50295786(N-(3-(diethylamino)-2-hydroxypropoxy)benzo[d]oxazo...)
Affinity DataEC50:  2.71E+4nMAssay Description:Transcriptional activation of HSF1 in heat shock stress-induced human HeLa cells assessed as granule formation treated 1 hr before heat shock challen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetHeat shock factor protein 1(Human)
Cytrx

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50414476BDBM50414476(CHEMBL2021569)
Affinity DataEC50:  2.86E+4nMAssay Description:Transcriptional activation of HSF1 in heat shock stress-induced human HeLa cells assessed as granule formation treated 1 hr before heat shock challen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetHeat shock factor protein 1(Human)
Cytrx

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50295806BDBM50295806(N-(2-hydroxy-3-((2-hydroxyethyl)(isopropyl)amino)p...)
Affinity DataEC50:  2.87E+4nMAssay Description:Transcriptional activation of HSF1 in heat shock stress-induced human HeLa cells assessed as granule formation treated 1 hr before heat shock challen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetHeat shock factor protein 1(Human)
Cytrx

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50295802BDBM50295802(6-fluoro-N-(2-hydroxy-3-(piperidin-1-yl)propoxy)be...)
Affinity DataEC50:  2.94E+4nMAssay Description:Transcriptional activation of HSF1 in heat shock stress-induced human HeLa cells assessed as granule formation treated 1 hr before heat shock challen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetHeat shock factor protein 1(Human)
Cytrx

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50295798BDBM50295798(N-(2-hydroxy-3-(piperidin-1-yl)propoxy)-6-methylbe...)
Affinity DataEC50:  3.10E+4nMAssay Description:Transcriptional activation of HSF1 in heat shock stress-induced human HeLa cells assessed as granule formation treated 1 hr before heat shock challen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetHeat shock factor protein 1(Human)
Cytrx

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50414475BDBM50414475(CHEMBL2021570)
Affinity DataEC50:  3.19E+4nMAssay Description:Transcriptional activation of HSF1 in heat shock stress-induced human HeLa cells assessed as granule formation treated 1 hr before heat shock challen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetHeat shock factor protein 1(Human)
Cytrx

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50295787BDBM50295787(N-(3-(2,6-dimethylpiperidin-1-yl)-2-hydroxypropoxy...)
Affinity DataEC50:  3.24E+4nMAssay Description:Transcriptional activation of HSF1 in heat shock stress-induced human HeLa cells assessed as granule formation treated 1 hr before heat shock challen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetHeat shock factor protein 1(Human)
Cytrx

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50295799BDBM50295799(N-(2-hydroxy-3-(piperidin-1-yl)propoxy)-5-methylbe...)
Affinity DataEC50:  4.16E+4nMAssay Description:Transcriptional activation of HSF1 in heat shock stress-induced human HeLa cells assessed as granule formation treated 1 hr before heat shock challen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetHeat shock factor protein 1(Human)
Cytrx

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50295794BDBM50295794(6-(N,N-dimethylsulfamoyl)-N-(2-hydroxy-3-(piperidi...)
Affinity DataEC50:  4.16E+4nMAssay Description:Transcriptional activation of HSF1 in heat shock stress-induced human HeLa cells assessed as granule formation treated 1 hr before heat shock challen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetHeat shock factor protein 1(Human)
Cytrx

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50295792BDBM50295792(N-(2-hydroxy-3-(piperidin-1-yl)propoxy)benzo[d]oxa...)
Affinity DataEC50:  4.17E+4nMAssay Description:Transcriptional activation of HSF1 in heat shock stress-induced human HeLa cells assessed as granule formation treated 1 hr before heat shock challen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetHeat shock factor protein 1(Human)
Cytrx

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50295795BDBM50295795(5-(ethylsulfonyl)-N-(2-hydroxy-3-(piperidin-1-yl)p...)
Affinity DataEC50:  4.29E+4nMAssay Description:Transcriptional activation of HSF1 in heat shock stress-induced human HeLa cells assessed as granule formation treated 1 hr before heat shock challen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetHeat shock factor protein 1(Human)
Cytrx

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50295803BDBM50295803(5-fluoro-N-(2-hydroxy-3-(piperidin-1-yl)propoxy)be...)
Affinity DataEC50:  5.13E+4nMAssay Description:Transcriptional activation of HSF1 in heat shock stress-induced human HeLa cells assessed as granule formation treated 1 hr before heat shock challen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetHeat shock factor protein 1(Human)
Cytrx

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50295791BDBM50295791(N-(2-hydroxy-3-(piperidin-1-yl)propoxy)benzo[d]thi...)
Affinity DataEC50:  5.26E+4nMAssay Description:Transcriptional activation of HSF1 in heat shock stress-induced human HeLa cells assessed as granule formation treated 1 hr before heat shock challen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetHeat shock factor protein 1(Human)
Cytrx

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50295789BDBM50295789(N-(3-(3-fluoropiperidin-1-yl)-2-hydroxypropoxy)ben...)
Affinity DataEC50:  5.26E+4nMAssay Description:Transcriptional activation of HSF1 in heat shock stress-induced human HeLa cells assessed as granule formation treated 1 hr before heat shock challen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetHeat shock factor protein 1(Human)
Cytrx

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50295790BDBM50295790(N-(2-hydroxy-3-(pyrrolidin-1-yl)propoxy)benzo[d]th...)
Affinity DataEC50:  6.28E+4nMAssay Description:Transcriptional activation of HSF1 in heat shock stress-induced human HeLa cells assessed as granule formation treated 1 hr before heat shock challen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed