Compile Data Set for Download or QSAR
Report error Found 21 Enz. Inhib. hit(s) with all data for entry = 50030429
TargetSerine/threonine-protein kinase Sgk1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50296010BDBM50296010(2-isobutyl-4-(5-phenyl-1H-pyrrolo[2,3-b]pyridin-3-...)
Affinity DataIC50: 5nMAssay Description:Inhibition of SGK1 by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Sgk1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50296011BDBM50296011(2-cyclopentyl-4-(5-phenyl-1H-pyrrolo[2,3-b]pyridin...)
Affinity DataIC50: 13nMAssay Description:Inhibition of SGK1 by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Sgk1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50296009BDBM50296009(2-ethyl-4-(5-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl)...)
Affinity DataIC50: 20nMAssay Description:Inhibition of SGK1 by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Sgk1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50296015BDBM50296015(2-(4-(5-(3-cyanophenyl)-1H-pyrrolo[2,3-b]pyridin-3...)
Affinity DataIC50: 40nMAssay Description:Inhibition of SGK1 by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Sgk1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50296003BDBM50296003(4-(5-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl)benzoic ...)
Affinity DataIC50: 40nMAssay Description:Inhibition of SGK1 by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Sgk1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50296014BDBM50296014(2-methyl-2-(4-(5-phenyl-1H-pyrrolo[2,3-b]pyridin-3...)
Affinity DataIC50: 50nMAssay Description:Inhibition of SGK1 by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Sgk1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50296013BDBM50296013(2-methyl-2-(4-(5-(naphthalen-2-yl)-1H-pyrrolo[2,3-...)
Affinity DataIC50: 63nMAssay Description:Inhibition of SGK1 by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Sgk1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50296004BDBM50296004([4-(5-naphthalen-2-yl-1H-pyrrolo[2,3-b]pyridin-3-y...)
Affinity DataIC50: 63nMAssay Description:Inhibition of SGK1 by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Sgk1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50296012BDBM50296012(2-(4-(5-(naphthalen-2-yl)-1H-pyrrolo[2,3-b]pyridin...)
Affinity DataIC50: 125nMAssay Description:Inhibition of SGK1 by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Sgk1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50296008BDBM50296008(3-(4-(1H-tetrazol-5-yl)phenyl)-5-phenyl-1H-pyrrolo...)
Affinity DataIC50: 160nMAssay Description:Inhibition of SGK1 by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Sgk1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50296007BDBM50296007((4-(5-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl)phenyl)...)
Affinity DataIC50: 400nMAssay Description:Inhibition of SGK1 by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Sgk1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50296010BDBM50296010(2-isobutyl-4-(5-phenyl-1H-pyrrolo[2,3-b]pyridin-3-...)
Affinity DataIC50: 580nMAssay Description:Inhibition of SGK1-mediated epithelial sodium channel activity in human M-1 cells assessed as short circuit current by whole cell electrophysiologica...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Sgk1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50296011BDBM50296011(2-cyclopentyl-4-(5-phenyl-1H-pyrrolo[2,3-b]pyridin...)
Affinity DataIC50: 580nMAssay Description:Inhibition of SGK1-mediated epithelial sodium channel activity in human M-1 cells assessed as short circuit current by whole cell electrophysiologica...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Sgk1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50296009BDBM50296009(2-ethyl-4-(5-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl)...)
Affinity DataIC50: 710nMAssay Description:Inhibition of SGK1-mediated epithelial sodium channel activity in human M-1 cells assessed as short circuit current by whole cell electrophysiologica...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Sgk1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50296013BDBM50296013(2-methyl-2-(4-(5-(naphthalen-2-yl)-1H-pyrrolo[2,3-...)
Affinity DataIC50: 870nMAssay Description:Inhibition of SGK1-mediated epithelial sodium channel activity in human M-1 cells assessed as short circuit current by whole cell electrophysiologica...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Sgk1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50296004BDBM50296004([4-(5-naphthalen-2-yl-1H-pyrrolo[2,3-b]pyridin-3-y...)
Affinity DataIC50: 880nMAssay Description:Inhibition of SGK1-mediated epithelial sodium channel activity in human M-1 cells assessed as short circuit current by whole cell electrophysiologica...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Sgk1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50296003BDBM50296003(4-(5-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl)benzoic ...)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of SGK1-mediated epithelial sodium channel activity in human M-1 cells assessed as short circuit current by whole cell electrophysiologica...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Sgk1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50296014BDBM50296014(2-methyl-2-(4-(5-phenyl-1H-pyrrolo[2,3-b]pyridin-3...)
Affinity DataIC50: 1.46E+3nMAssay Description:Inhibition of SGK1-mediated epithelial sodium channel activity in human M-1 cells assessed as short circuit current by whole cell electrophysiologica...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Sgk1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50296015BDBM50296015(2-(4-(5-(3-cyanophenyl)-1H-pyrrolo[2,3-b]pyridin-3...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of SGK1-mediated epithelial sodium channel activity in human M-1 cells assessed as short circuit current by whole cell electrophysiologica...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Sgk1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50296005BDBM50296005(methyl 4-(5-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl)b...)
Affinity DataIC50: 3.16E+3nMAssay Description:Inhibition of SGK1 by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Sgk1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50296006BDBM50296006(1-(4-(5-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl)pheny...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of SGK1 by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed