Compile Data Set for Download or QSAR
maximum 50k data
Found 93 Enz. Inhib. hit(s) with all data for entry = 50030535
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Astrazeneca R & D M£Lndal

Curated by ChEMBL
LigandPNGBDBM50297624(1-phenyl-N-(1-((1-(4-(trifluoromethyl)phenyl)-1H-p...)
Affinity DataIC50:  10nMAssay Description:Displacement of [125I]MCH from human MCH1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Astrazeneca R & D M£Lndal

Curated by ChEMBL
LigandPNGBDBM50297625(1-(2-(3,5-dimethyl-1H-pyrazol-1-yl)-1-phenylethyl)...)
Affinity DataIC50:  11nMAssay Description:Displacement of [125I]MCH from human MCH1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Astrazeneca R & D M£Lndal

Curated by ChEMBL
LigandPNGBDBM50297626(2-(4-fluorophenyl)-N-(1-((1-(4-(trifluoromethyl)ph...)
Affinity DataIC50:  13nMAssay Description:Displacement of [125I]MCH from human MCH1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Astrazeneca R & D M£Lndal

Curated by ChEMBL
LigandPNGBDBM50297627(1-(1-phenyl-2-(pyrazin-2-yl)ethyl)-3-(1-((1-(4-(tr...)
Affinity DataIC50:  17nMAssay Description:Displacement of [125I]MCH from human MCH1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Astrazeneca R & D M£Lndal

Curated by ChEMBL
LigandPNGBDBM50297628(1-(1-phenyl-2-(1H-pyrazol-1-yl)ethyl)-3-(1-((1-(4-...)
Affinity DataIC50:  19nMAssay Description:Displacement of [125I]MCH from human MCH1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Astrazeneca R & D M£Lndal

Curated by ChEMBL
LigandPNGBDBM50297629(2-(pyridin-3-yl)-N-(1-((1-(4-(trifluoromethyl)phen...)
Affinity DataIC50:  21nMAssay Description:Displacement of [125I]MCH from human MCH1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Astrazeneca R & D M£Lndal

Curated by ChEMBL
LigandPNGBDBM50297630(3-(hydroxymethyl)-N-(1-((1-(4-(trifluoromethyl)phe...)
Affinity DataIC50:  23nMAssay Description:Displacement of [125I]MCH from human MCH1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Astrazeneca R & D M£Lndal

Curated by ChEMBL
LigandPNGBDBM50297621(1-(2-(1H-imidazol-1-yl)-1-phenylethyl)-3-(1-((1-(4...)
Affinity DataIC50:  25nMAssay Description:Displacement of [125I]MCH from human MCH1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Astrazeneca R & D M£Lndal

Curated by ChEMBL
LigandPNGBDBM50297631(2-(pyridin-3-ylmethyl)-N-(1-((1-(4-(trifluoromethy...)
Affinity DataIC50:  26nMAssay Description:Displacement of [125I]MCH from human MCH1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Astrazeneca R & D M£Lndal

Curated by ChEMBL
LigandPNGBDBM50297632(1-((1H-imidazol-2-yl)(phenyl)methyl)-3-(1-((1-(4-(...)
Affinity DataIC50:  27nMAssay Description:Displacement of [125I]MCH from human MCH1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Astrazeneca R & D M£Lndal

Curated by ChEMBL
LigandPNGBDBM50297633(4-methyl-2-phenyl-N-(1-((1-(4-(trifluoromethyl)phe...)
Affinity DataIC50:  28nMAssay Description:Displacement of [125I]MCH from human MCH1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Astrazeneca R & D M£Lndal

Curated by ChEMBL
LigandPNGBDBM50245454(2-(3-chlorophenoxy)-N-(1-((1-(4-(trifluoromethyl)p...)
Affinity DataIC50:  29nMAssay Description:Displacement of [125I]MCH from human MCH1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Astrazeneca R & D M£Lndal

Curated by ChEMBL
LigandPNGBDBM50297634((S)-1-(2-hydroxy-1-phenylethyl)-3-(1-((1-(4-(trifl...)
Affinity DataIC50:  35nMAssay Description:Displacement of [125I]MCH from human MCH1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Astrazeneca R & D M£Lndal

Curated by ChEMBL
LigandPNGBDBM50297635(4-(2-hydroxyphenyl)-N-(1-((1-(4-(trifluoromethyl)p...)
Affinity DataIC50:  36nMAssay Description:Displacement of [125I]MCH from human MCH1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Astrazeneca R & D M£Lndal

Curated by ChEMBL
LigandPNGBDBM50297620(1-(1-phenyl-2-(1H-1,2,4-triazol-1-yl)ethyl)-3-(1-(...)
Affinity DataIC50:  38nMAssay Description:Displacement of [125I]MCH from human MCH1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Astrazeneca R & D M£Lndal

Curated by ChEMBL
LigandPNGBDBM50297636(1-(3-fluorobenzyl)-3-(1-((1-(4-(trifluoromethyl)ph...)
Affinity DataIC50:  39nMAssay Description:Displacement of [125I]MCH from human MCH1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Astrazeneca R & D M£Lndal

Curated by ChEMBL
LigandPNGBDBM50297637(2-(2-hydroxyethyl)-N-(1-((1-(4-(trifluoromethyl)ph...)
Affinity DataIC50:  39nMAssay Description:Displacement of [125I]MCH from human MCH1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Astrazeneca R & D M£Lndal

Curated by ChEMBL
LigandPNGBDBM50297638(3-(pyrrolidine-1-carbonyl)-N-(1-((1-(4-(trifluorom...)
Affinity DataIC50:  40nMAssay Description:Displacement of [125I]MCH from human MCH1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Astrazeneca R & D M£Lndal

Curated by ChEMBL
LigandPNGBDBM50297621(1-(2-(1H-imidazol-1-yl)-1-phenylethyl)-3-(1-((1-(4...)
Affinity DataIC50:  40nMAssay Description:Inhibition of human recombinant CYP3A4 after 45 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Astrazeneca R & D M£Lndal

Curated by ChEMBL
LigandPNGBDBM50297617(1-((1-hydroxycyclohexyl)methyl)-3-(1-((1-(4-(trifl...)
Affinity DataIC50:  44nMAssay Description:Displacement of [125I]MCH from human MCH1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Astrazeneca R & D M£Lndal

Curated by ChEMBL
LigandPNGBDBM50297646(1-(((1S,2R)-2-hydroxycyclohexyl)methyl)-3-(1-((1-(...)
Affinity DataIC50:  46nMAssay Description:Displacement of [125I]MCH from human MCH1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Astrazeneca R & D M£Lndal

Curated by ChEMBL
LigandPNGBDBM50297639(3-(4-methoxyphenoxy)-N-(1-((1-(4-(trifluoromethyl)...)
Affinity DataIC50:  49nMAssay Description:Displacement of [125I]MCH from human MCH1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Astrazeneca R & D M£Lndal

Curated by ChEMBL
LigandPNGBDBM50297640(1-((1-hydroxycyclohexyl)methyl)-1-methyl-3-(1-((1-...)
Affinity DataIC50:  57nMAssay Description:Displacement of [125I]MCH from human MCH1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Astrazeneca R & D M£Lndal

Curated by ChEMBL
LigandPNGBDBM50297647(4-benzyl-4-hydroxy-N-(1-((1-(4-(trifluoromethyl)ph...)
Affinity DataIC50:  63nMAssay Description:Displacement of [125I]MCH from human MCH1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Astrazeneca R & D M£Lndal

Curated by ChEMBL
LigandPNGBDBM50297644(1-(((1R,2R)-2-hydroxycyclohexyl)methyl)-3-(1-((1-(...)
Affinity DataIC50:  63nMAssay Description:Displacement of [125I]MCH from human MCH1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Astrazeneca R & D M£Lndal

Curated by ChEMBL
LigandPNGBDBM50297645(1-(2-morpholino-1-phenylethyl)-3-(1-((1-(4-(triflu...)
Affinity DataIC50:  66nMAssay Description:Displacement of [125I]MCH from human MCH1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Astrazeneca R & D M£Lndal

Curated by ChEMBL
LigandPNGBDBM50297619(1-(2-(2-methyl-1H-imidazol-1-yl)-1-phenylethyl)-3-...)
Affinity DataIC50:  74nMAssay Description:Displacement of [125I]MCH from human MCH1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Astrazeneca R & D M£Lndal

Curated by ChEMBL
LigandPNGBDBM50297643(CHEMBL550535 | N-(1-((1-(4-(trifluoromethyl)phenyl...)
Affinity DataIC50:  81.8nMAssay Description:Displacement of [125I]MCH from human MCH1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Astrazeneca R & D M£Lndal

Curated by ChEMBL
LigandPNGBDBM50297618(1-(3-Hydroxy-adamantan-1-yl)-3-{1-[1-(4-trifluorom...)
Affinity DataIC50:  82nMAssay Description:Displacement of [125I]MCH from human MCH1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Astrazeneca R & D M£Lndal

Curated by ChEMBL
LigandPNGBDBM50297648(1-((1H-benzo[d]imidazol-2-yl)methyl)-3-(1-((1-(4-(...)
Affinity DataIC50:  90nMAssay Description:Displacement of [125I]MCH from human MCH1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Astrazeneca R & D M£Lndal

Curated by ChEMBL
LigandPNGBDBM50297653(3-(1,1-Dioxo-1lambda6-thiomorpholin-4-yl)-azetidin...)
Affinity DataIC50:  99nMAssay Description:Displacement of [125I]MCH from human MCH1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Astrazeneca R & D M£Lndal

Curated by ChEMBL
LigandPNGBDBM50297642(1-(4-chloro-2-(hydroxymethyl)phenyl)-3-(1-((1-(4-(...)
Affinity DataIC50:  111nMAssay Description:Displacement of [125I]MCH from human MCH1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Astrazeneca R & D M£Lndal

Curated by ChEMBL
LigandPNGBDBM50297650(1-(1-(1H-imidazol-1-yl)-3-methylbutan-2-yl)-3-(1-(...)
Affinity DataIC50:  112nMAssay Description:Displacement of [125I]MCH from human MCH1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Astrazeneca R & D M£Lndal

Curated by ChEMBL
LigandPNGBDBM50297654(3-acetamido-N-(1-((1-(4-(trifluoromethyl)phenyl)-1...)
Affinity DataIC50:  120nMAssay Description:Displacement of [125I]MCH from human MCH1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Astrazeneca R & D M£Lndal

Curated by ChEMBL
LigandPNGBDBM50297616((S)-3-hydroxy-N-(1-((1-(4-(trifluoromethyl)phenyl)...)
Affinity DataIC50:  125nMAssay Description:Displacement of [125I]MCH from human MCH1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Astrazeneca R & D M£Lndal

Curated by ChEMBL
LigandPNGBDBM50297615((R)-3-hydroxy-N-(1-((1-(4-(trifluoromethyl)phenyl)...)
Affinity DataIC50:  138nMAssay Description:Displacement of [125I]MCH from human MCH1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Astrazeneca R & D M£Lndal

Curated by ChEMBL
LigandPNGBDBM50297651((R)-1-(2-hydroxy-1-phenylethyl)-3-(1-((1-(4-(trifl...)
Affinity DataIC50:  152nMAssay Description:Displacement of [125I]MCH from human MCH1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Astrazeneca R & D M£Lndal

Curated by ChEMBL
LigandPNGBDBM50297649(5-chloro-6-oxo-N-(1-((1-(4-(trifluoromethyl)phenyl...)
Affinity DataIC50:  196nMAssay Description:Displacement of [125I]MCH from human MCH1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Astrazeneca R & D M£Lndal

Curated by ChEMBL
LigandPNGBDBM50297641(3-(1,4-oxazepan-4-yl)-N-(1-((1-(4-(trifluoromethyl...)
Affinity DataIC50:  236nMAssay Description:Displacement of [125I]MCH from human MCH1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Astrazeneca R & D M£Lndal

Curated by ChEMBL
LigandPNGBDBM50297622(1-(1-(1H-imidazol-1-yl)propan-2-yl)-3-(1-((1-(4-(t...)
Affinity DataIC50:  308nMAssay Description:Displacement of [125I]MCH from human MCH1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Astrazeneca R & D M£Lndal

Curated by ChEMBL
LigandPNGBDBM50297622(1-(1-(1H-imidazol-1-yl)propan-2-yl)-3-(1-((1-(4-(t...)
Affinity DataIC50:  320nMAssay Description:Inhibition of human recombinant CYP3A4 after 45 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Astrazeneca R & D M£Lndal

Curated by ChEMBL
LigandPNGBDBM50297623(3-phenyl-3-(3-(1-((1-(4-(trifluoromethyl)phenyl)-1...)
Affinity DataIC50:  412nMAssay Description:Displacement of [125I]MCH from human MCH1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Astrazeneca R & D M£Lndal

Curated by ChEMBL
LigandPNGBDBM50245454(2-(3-chlorophenoxy)-N-(1-((1-(4-(trifluoromethyl)p...)
Affinity DataIC50:  560nMAssay Description:Inhibition of human ERG expressed in CHO cells by patch-clamp assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Astrazeneca R & D M£Lndal

Curated by ChEMBL
LigandPNGBDBM50297620(1-(1-phenyl-2-(1H-1,2,4-triazol-1-yl)ethyl)-3-(1-(...)
Affinity DataIC50:  570nMAssay Description:Inhibition of human recombinant CYP3A4 after 45 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Astrazeneca R & D M£Lndal

Curated by ChEMBL
LigandPNGBDBM50297652(4-fluoro-N-(1-((1-(4-(trifluoromethyl)phenyl)-1H-p...)
Affinity DataIC50:  617nMAssay Description:Displacement of [125I]MCH from human MCH1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Astrazeneca R & D M£Lndal

Curated by ChEMBL
LigandPNGBDBM50297625(1-(2-(3,5-dimethyl-1H-pyrazol-1-yl)-1-phenylethyl)...)
Affinity DataIC50:  790nMAssay Description:Inhibition of human recombinant CYP3A4 after 45 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Astrazeneca R & D M£Lndal

Curated by ChEMBL
LigandPNGBDBM50297636(1-(3-fluorobenzyl)-3-(1-((1-(4-(trifluoromethyl)ph...)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of human ERG expressed in CHO cells by patch-clamp assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Astrazeneca R & D M£Lndal

Curated by ChEMBL
LigandPNGBDBM50297624(1-phenyl-N-(1-((1-(4-(trifluoromethyl)phenyl)-1H-p...)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of human ERG expressed in CHO cells by patch-clamp assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Astrazeneca R & D M£Lndal

Curated by ChEMBL
LigandPNGBDBM50297631(2-(pyridin-3-ylmethyl)-N-(1-((1-(4-(trifluoromethy...)
Affinity DataIC50:  1.73E+3nMAssay Description:Inhibition of human ERG expressed in CHO cells by patch-clamp assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Astrazeneca R & D M£Lndal

Curated by ChEMBL
LigandPNGBDBM50297626(2-(4-fluorophenyl)-N-(1-((1-(4-(trifluoromethyl)ph...)
Affinity DataIC50:  1.81E+3nMAssay Description:Inhibition of human ERG expressed in CHO cells by patch-clamp assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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