Compile Data Set for Download or QSAR
maximum 50k data
Found 49 Enz. Inhib. hit(s) with all data for entry = 50030557
TargetProgesterone receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50298032((S)-2-chloro-4-((2-chlorobenzyl)(1-(cyanomethyl)py...)
Affinity DataIC50:  8nMAssay Description:Binding affinity to PR by fluorescence polarization based competition binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50298033((S)-ethyl 2-(3-((3-chloro-4-cyanophenyl)(2-chlorob...)
Affinity DataIC50:  8nMAssay Description:Binding affinity to PR by fluorescence polarization based competition binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50298030((S)-2-chloro-4-((2-chlorobenzyl)(1-(3,3,3-trifluor...)
Affinity DataIC50:  13nMAssay Description:Binding affinity to PR by fluorescence polarization based competition binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50298028((S)-2-chloro-4-((1-methylpyrrolidin-3-yl)(2-(trifl...)
Affinity DataIC50:  16nMAssay Description:Binding affinity to PR by fluorescence polarization based competition binding assayMore data for this Ligand-Target Pair
TargetProgesterone receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50298035((S)-2-chloro-4-((2-chlorobenzyl)(1-(pyridin-2-ylme...)
Affinity DataIC50:  20nMAssay Description:Binding affinity to PR by fluorescence polarization based competition binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50298043((S)-2-chloro-4-((2-chlorobenzyl)(1-methylpyrrolidi...)
Affinity DataIC50:  20nMAssay Description:Binding affinity to PR by fluorescence polarization based competition binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50298029((S)-2-chloro-4-((2-chlorobenzyl)(1-isopropylpyrrol...)
Affinity DataIC50:  20nMAssay Description:Binding affinity to PR by fluorescence polarization based competition binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50298031((S)-2-chloro-4-((2-chlorobenzyl)(1-(2-methoxyethyl...)
Affinity DataIC50:  25nMAssay Description:Binding affinity to PR by fluorescence polarization based competition binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50298041((S)-4-(benzyl(1-methylpyrrolidin-3-yl)amino)-2-chl...)
Affinity DataIC50:  40nMAssay Description:Binding affinity to PR by fluorescence polarization based competition binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50298046((S)-2-chloro-4-((2,6-dichlorobenzyl)(1-methylpyrro...)
Affinity DataIC50:  40nMAssay Description:Binding affinity to PR by fluorescence polarization based competition binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50298047((S)-2-chloro-4-((2-methylbenzyl)(1-methylpyrrolidi...)
Affinity DataIC50:  50nMAssay Description:Binding affinity to PR by fluorescence polarization based competition binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50298034((S)-2-(3-((3-chloro-4-cyanophenyl)(2-chlorobenzyl)...)
Affinity DataIC50:  63nMAssay Description:Binding affinity to PR by fluorescence polarization based competition binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50298040((S)-2-chloro-4-((cyclohexylmethyl)(1-methylpyrroli...)
Affinity DataIC50:  79nMAssay Description:Binding affinity to PR by fluorescence polarization based competition binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50298036(CHEMBL549725 | rac 2-((4-cyano-3-(trifluoromethyl)...)
Affinity DataIC50:  125nMAssay Description:Binding affinity to PR by fluorescence polarization based competition binding assayMore data for this Ligand-Target Pair
TargetProgesterone receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50298044((S)-2-chloro-4-((3-chlorobenzyl)(1-methylpyrrolidi...)
Affinity DataIC50:  160nMAssay Description:Binding affinity to PR by fluorescence polarization based competition binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50298028((S)-2-chloro-4-((1-methylpyrrolidin-3-yl)(2-(trifl...)
Affinity DataIC50:  250nMAssay Description:Binding affinity to AR by fluorescence polarization based competition binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50298039((S)-4-(butyl(1-methylpyrrolidin-3-yl)amino)-2-chlo...)
Affinity DataIC50:  250nMAssay Description:Binding affinity to PR by fluorescence polarization based competition binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50298045((S)-2-chloro-4-((4-chlorobenzyl)(1-methylpyrrolidi...)
Affinity DataIC50:  400nMAssay Description:Binding affinity to PR by fluorescence polarization based competition binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50298038((S)-2-chloro-4-((1-methylpyrrolidin-3-yl)(propyl)a...)
Affinity DataIC50:  400nMAssay Description:Binding affinity to PR by fluorescence polarization based competition binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50298037((S)-2-chloro-4-(ethyl(1-methylpyrrolidin-3-yl)amin...)
Affinity DataIC50:  1.30E+3nMAssay Description:Binding affinity to PR by fluorescence polarization based competition binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50298036(CHEMBL549725 | rac 2-((4-cyano-3-(trifluoromethyl)...)
Affinity DataIC50:  1.60E+3nMAssay Description:Binding affinity to AR by fluorescence polarization based competition binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50298042((S)-2-chloro-4-((1-methylpyrrolidin-3-yl)(pyridin-...)
Affinity DataIC50:  3.00E+3nMAssay Description:Binding affinity to PR by fluorescence polarization based competition binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50298028((S)-2-chloro-4-((1-methylpyrrolidin-3-yl)(2-(trifl...)
Affinity DataIC50: >1.00E+4nMAssay Description:Binding affinity to ERbeta by fluorescence polarization based competition binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50298036(CHEMBL549725 | rac 2-((4-cyano-3-(trifluoromethyl)...)
Affinity DataIC50: >1.00E+4nMAssay Description:Binding affinity to ERbeta by fluorescence polarization based competition binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50298036(CHEMBL549725 | rac 2-((4-cyano-3-(trifluoromethyl)...)
Affinity DataIC50: >1.00E+4nMAssay Description:Binding affinity to GR by fluorescence polarization based competition binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMineralocorticoid receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50298036(CHEMBL549725 | rac 2-((4-cyano-3-(trifluoromethyl)...)
Affinity DataIC50: >1.00E+4nMAssay Description:Binding affinity to MR by fluorescence polarization based competition binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50298028((S)-2-chloro-4-((1-methylpyrrolidin-3-yl)(2-(trifl...)
Affinity DataEC50:  7.90E+3nMAssay Description:Antagonist activity at GR expressed in human A549 cell lineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMineralocorticoid receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50298028((S)-2-chloro-4-((1-methylpyrrolidin-3-yl)(2-(trifl...)
Affinity DataEC50:  5.00E+3nMAssay Description:Agonist activity at MR expressed in african green monkey CV-1 cells by luciferase reporter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50298047((S)-2-chloro-4-((2-methylbenzyl)(1-methylpyrrolidi...)
Affinity DataEC50:  200nMAssay Description:Agonist activity at PR expressed in african green monkey CV-1 cells by luciferase reporter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50298046((S)-2-chloro-4-((2,6-dichlorobenzyl)(1-methylpyrro...)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at PR expressed in african green monkey CV-1 cells by luciferase reporter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50298045((S)-2-chloro-4-((4-chlorobenzyl)(1-methylpyrrolidi...)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at PR expressed in african green monkey CV-1 cells by luciferase reporter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50298044((S)-2-chloro-4-((3-chlorobenzyl)(1-methylpyrrolidi...)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at PR expressed in african green monkey CV-1 cells by luciferase reporter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50298043((S)-2-chloro-4-((2-chlorobenzyl)(1-methylpyrrolidi...)
Affinity DataEC50:  1.60nMAssay Description:Agonist activity at PR expressed in african green monkey CV-1 cells by luciferase reporter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50298042((S)-2-chloro-4-((1-methylpyrrolidin-3-yl)(pyridin-...)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at PR expressed in african green monkey CV-1 cells by luciferase reporter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50298041((S)-4-(benzyl(1-methylpyrrolidin-3-yl)amino)-2-chl...)
Affinity DataEC50:  1.30E+3nMAssay Description:Agonist activity at PR expressed in african green monkey CV-1 cells by luciferase reporter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50298040((S)-2-chloro-4-((cyclohexylmethyl)(1-methylpyrroli...)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at PR expressed in african green monkey CV-1 cells by luciferase reporter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50298039((S)-4-(butyl(1-methylpyrrolidin-3-yl)amino)-2-chlo...)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at PR expressed in african green monkey CV-1 cells by luciferase reporter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50298038((S)-2-chloro-4-((1-methylpyrrolidin-3-yl)(propyl)a...)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at PR expressed in african green monkey CV-1 cells by luciferase reporter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50298037((S)-2-chloro-4-(ethyl(1-methylpyrrolidin-3-yl)amin...)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at PR expressed in african green monkey CV-1 cells by luciferase reporter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50298036(CHEMBL549725 | rac 2-((4-cyano-3-(trifluoromethyl)...)
Affinity DataEC50:  1.30E+3nMAssay Description:Agonist activity at PR expressed in african green monkey CV-1 cells by luciferase reporter assayMore data for this Ligand-Target Pair
TargetProgesterone receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50298028((S)-2-chloro-4-((1-methylpyrrolidin-3-yl)(2-(trifl...)
Affinity DataEC50:  9nMAssay Description:Agonist activity at PR expressed in human T47D cellsMore data for this Ligand-Target Pair
TargetProgesterone receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50298035((S)-2-chloro-4-((2-chlorobenzyl)(1-(pyridin-2-ylme...)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at PR expressed in african green monkey CV-1 cells by luciferase reporter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50298034((S)-2-(3-((3-chloro-4-cyanophenyl)(2-chlorobenzyl)...)
Affinity DataEC50:  200nMAssay Description:Agonist activity at PR expressed in african green monkey CV-1 cells by luciferase reporter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50298033((S)-ethyl 2-(3-((3-chloro-4-cyanophenyl)(2-chlorob...)
Affinity DataEC50:  10nMAssay Description:Agonist activity at PR expressed in african green monkey CV-1 cells by luciferase reporter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50298032((S)-2-chloro-4-((2-chlorobenzyl)(1-(cyanomethyl)py...)
Affinity DataEC50:  0.5nMAssay Description:Agonist activity at PR expressed in african green monkey CV-1 cells by luciferase reporter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50298031((S)-2-chloro-4-((2-chlorobenzyl)(1-(2-methoxyethyl...)
Affinity DataEC50:  50nMAssay Description:Agonist activity at PR expressed in african green monkey CV-1 cells by luciferase reporter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50298030((S)-2-chloro-4-((2-chlorobenzyl)(1-(3,3,3-trifluor...)
Affinity DataEC50:  200nMAssay Description:Agonist activity at PR expressed in african green monkey CV-1 cells by luciferase reporter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50298029((S)-2-chloro-4-((2-chlorobenzyl)(1-isopropylpyrrol...)
Affinity DataEC50:  200nMAssay Description:Agonist activity at PR expressed in african green monkey CV-1 cells by luciferase reporter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50298028((S)-2-chloro-4-((1-methylpyrrolidin-3-yl)(2-(trifl...)
Affinity DataEC50:  3nMAssay Description:Agonist activity at PR expressed in african green monkey CV-1 cells by luciferase reporter assayMore data for this Ligand-Target Pair