Compile Data Set for Download or QSAR
Report error Found 29 Enz. Inhib. hit(s) with all data for entry = 50030761
TargetSodium-dependent noradrenaline transporter(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM35229(Desmethylimipramine | 3-(10,11-dihydro-5H-dibenzo[...)
Affinity DataIC50: 3.40nMAssay Description:Inhibition of norepinephrine reuptake at human NET expressed in MDCK-Net6 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSodium-dependent serotonin transporter(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM30130(Prozac | cid_62857 | Fluoxetin | CHEMBL41 | CHEMBL...)
Affinity DataIC50: 9.40nMAssay Description:Inhibition of serotonin uptake at human SERT expressed in JAR cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50301004((+/-)-Erythro--1-(5-chloro-1H-indol-1-yl)-3-(methy...)
Affinity DataIC50: 10nMAssay Description:Inhibition of serotonin uptake at human SERT expressed in JAR cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50297365((1S,2R)-1-(1H-indol-1-yl)-3-(methylamino)-1-phenyl...)
Affinity DataIC50: 23nMAssay Description:Displacement of [3H]Nisoxetine from human recombinant NET expressed in MDCK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50301003((+/-)-Erythro--1-(5-methoxy-1H-indol-1-yl)-3-(meth...)
Affinity DataIC50: 31nMAssay Description:Inhibition of serotonin uptake at human SERT expressed in JAR cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50300998((+/-)-Erythro--1-(3-methyl-1H-indol-1-yl)-3-(methy...)
Affinity DataIC50: 42nMAssay Description:Inhibition of norepinephrine reuptake at human NET expressed in MDCK-Net6 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50301004((+/-)-Erythro--1-(5-chloro-1H-indol-1-yl)-3-(methy...)
Affinity DataIC50: 49nMAssay Description:Inhibition of norepinephrine reuptake at human NET expressed in MDCK-Net6 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50301006((+/-)-Erythro--3-amino-1-(1H-indol-1-yl)-1-phenylp...)
Affinity DataIC50: 50nMAssay Description:Inhibition of serotonin uptake at human SERT expressed in JAR cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50300995(CHEMBL565309 | CHEMBL567041 | (2S,3R)-1-(1H-indol-...)
Affinity DataIC50: 74nMAssay Description:Inhibition of serotonin uptake at human SERT expressed in JAR cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50300995(CHEMBL565309 | CHEMBL567041 | (2S,3R)-1-(1H-indol-...)
Affinity DataIC50: 79nMAssay Description:Inhibition of norepinephrine reuptake at human NET expressed in MDCK-Net6 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50301000((+/-)-Erythro--1-(5-fluoro-1H-indol-1-yl)-3-(methy...)
Affinity DataIC50: 95nMAssay Description:Inhibition of serotonin uptake at human SERT expressed in JAR cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50300995(CHEMBL565309 | CHEMBL567041 | (2S,3R)-1-(1H-indol-...)
Affinity DataIC50: 104nMAssay Description:Inhibition of norepinephrine reuptake at human NET expressed in MDCK-Net6 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50301000((+/-)-Erythro--1-(5-fluoro-1H-indol-1-yl)-3-(methy...)
Affinity DataIC50: 118nMAssay Description:Inhibition of norepinephrine reuptake at human NET expressed in MDCK-Net6 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50297365((1S,2R)-1-(1H-indol-1-yl)-3-(methylamino)-1-phenyl...)
Affinity DataIC50: 126nMAssay Description:Inhibition of serotonin uptake at human SERT expressed in JAR cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50297365((1S,2R)-1-(1H-indol-1-yl)-3-(methylamino)-1-phenyl...)
Affinity DataIC50: 137nMAssay Description:Inhibition of norepinephrine reuptake at human NET expressed in MDCK-Net6 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50300995(CHEMBL565309 | CHEMBL567041 | (2S,3R)-1-(1H-indol-...)
Affinity DataIC50: 144nMAssay Description:Inhibition of serotonin uptake at human SERT expressed in JAR cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50301002((1R,2R)-1-(1H-indol-1-yl)-3-(methylamino)-1-phenyl...)
Affinity DataIC50: 150nMAssay Description:Inhibition of norepinephrine reuptake at human NET expressed in MDCK-Net6 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50301002((1R,2R)-1-(1H-indol-1-yl)-3-(methylamino)-1-phenyl...)
Affinity DataIC50: 161nMAssay Description:Inhibition of serotonin uptake at human SERT expressed in JAR cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50301003((+/-)-Erythro--1-(5-methoxy-1H-indol-1-yl)-3-(meth...)
Affinity DataIC50: 230nMAssay Description:Inhibition of norepinephrine reuptake at human NET expressed in MDCK-Net6 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50300998((+/-)-Erythro--1-(3-methyl-1H-indol-1-yl)-3-(methy...)
Affinity DataIC50: 251nMAssay Description:Inhibition of serotonin uptake at human SERT expressed in JAR cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50300996((+/-)-Erythro--3-(ethylamino)-1-(1H-indol-1-yl)-1-...)
Affinity DataIC50: 298nMAssay Description:Inhibition of serotonin uptake at human SERT expressed in JAR cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50300999((+/-)-Erythro--3-amino-1-(3-methyl-1H-indol-1-yl)-...)
Affinity DataIC50: 299nMAssay Description:Inhibition of serotonin uptake at human SERT expressed in JAR cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50300999((+/-)-Erythro--3-amino-1-(3-methyl-1H-indol-1-yl)-...)
Affinity DataIC50: 321nMAssay Description:Inhibition of norepinephrine reuptake at human NET expressed in MDCK-Net6 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50300994((+/-)-Erythro-1-(1H-indol-1-yl)-3-(methylamino)-1-...)
Affinity DataIC50: 415nMAssay Description:Inhibition of norepinephrine reuptake at human NET expressed in MDCK-Net6 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50300994((+/-)-Erythro-1-(1H-indol-1-yl)-3-(methylamino)-1-...)
Affinity DataIC50: 918nMAssay Description:Inhibition of serotonin uptake at human SERT expressed in JAR cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50300997((+/-)-Erythro--3-(ethylamino)-1-(3-methyl-1H-indol...)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of norepinephrine reuptake at human NET expressed in MDCK-Net6 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50300996((+/-)-Erythro--3-(ethylamino)-1-(1H-indol-1-yl)-1-...)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of norepinephrine reuptake at human NET expressed in MDCK-Net6 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50300997((+/-)-Erythro--3-(ethylamino)-1-(3-methyl-1H-indol...)
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of serotonin uptake at human SERT expressed in JAR cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50301005((+/-)-Erythro--3-(cyclohexylmethylamino)-1-(1H-ind...)
Affinity DataIC50: 2.83E+3nMAssay Description:Inhibition of serotonin uptake at human SERT expressed in JAR cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed