Compile Data Set for Download or QSAR
Report error Found 31 Enz. Inhib. hit(s) with all data for entry = 50031301
TargetC-C chemokine receptor type 5(Human)
Roche Palo Alto

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50310731BDBM50310731(4-butyl-3-(cyclohexylmethyl)-8-(1-(4,6-dimethylpyr...)
Affinity DataIC50: 7nMAssay Description:Displacement of [125I]RANTES from human CCR5 receptor co-transfected with Galphai6 in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Roche Palo Alto

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50310747BDBM50310747((5S)-5-butyl-9-(1-(2,4-dimethylnicotinoyl)-4-methy...)
Affinity DataIC50: 10nMAssay Description:Displacement of [125I]RANTES from human CCR5 receptor co-transfected with Galphai6 in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Roche Palo Alto

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50310730BDBM50310730(4-butyl-3-(cyclohexylmethyl)-8-(1-(2,6-dimethylben...)
Affinity DataIC50: 10nMAssay Description:Displacement of [125I]RANTES from human CCR5 receptor co-transfected with Galphai6 in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Roche Palo Alto

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50310744BDBM50310744((S)-5-butyl-9-(1-(4,6-dimethyl-2-oxo-2H-pyran-5-ca...)
Affinity DataIC50: 12nMAssay Description:Displacement of [125I]RANTES from human CCR5 receptor co-transfected with Galphai6 in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Roche Palo Alto

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50310726BDBM50310726(4-butyl-3-(cyclopentylmethyl)-8-(1-(2,6-dimethylbe...)
Affinity DataIC50: 18nMAssay Description:Displacement of [125I]RANTES from human CCR5 receptor co-transfected with Galphai6 in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Roche Palo Alto

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50310743BDBM50310743((S)-5-(4-(5-butyl-3-methyl-2-oxo-1-oxa-3,9-diazasp...)
Affinity DataIC50: 22nMAssay Description:Displacement of [125I]RANTES from human CCR5 receptor co-transfected with Galphai6 in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Roche Palo Alto

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50310727BDBM50310727(4-butyl-8-(1-(2,6-dimethylbenzoyl)piperidin-4-yl)-...)
Affinity DataIC50: 24nMAssay Description:Displacement of [125I]RANTES from human CCR5 receptor co-transfected with Galphai6 in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Roche Palo Alto

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50310742BDBM50310742((+/-)-5-(4-(5-butyl-2-oxo-3-((tetrahydro-2H-pyran-...)
Affinity DataIC50: 24nMAssay Description:Displacement of [125I]RANTES from human CCR5 receptor co-transfected with Galphai6 in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Roche Palo Alto

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50310737BDBM50310737(5-butyl-9-(1-(4,6-dimethylpyrimidine-5-carbonyl)-4...)
Affinity DataIC50: 25nMAssay Description:Displacement of [125I]RANTES from human CCR5 receptor co-transfected with Galphai6 in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Roche Palo Alto

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50310739BDBM50310739((S)-5-butyl-9-(1-(4,6-dimethylpyrimidine-5-carbony...)
Affinity DataIC50: 25nMAssay Description:Displacement of [125I]RANTES from human CCR5 receptor co-transfected with Galphai6 in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Roche Palo Alto

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50310746BDBM50310746((5S)-5-butyl-3-((4,4-difluorocyclohexyl)methyl)-9-...)
Affinity DataIC50: 27nMAssay Description:Displacement of [125I]RANTES from human CCR5 receptor co-transfected with Galphai6 in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Roche Palo Alto

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50310733BDBM50310733(5-butyl-3-(cyclohexylmethyl)-9-(1-(2,6-dimethylben...)
Affinity DataIC50: 30nMAssay Description:Displacement of [125I]RANTES from human CCR5 receptor co-transfected with Galphai6 in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Roche Palo Alto

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50310724BDBM50310724(4-butyl-3-(cyclohexylmethyl)-8-(1-(2,6-dimethylben...)
Affinity DataIC50: 51nMAssay Description:Displacement of [125I]RANTES from human CCR5 receptor co-transfected with Galphai6 in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Roche Palo Alto

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50310732BDBM50310732(4-butyl-8-(1-(4,6-dimethylpyrimidine-5-carbonyl)-4...)
Affinity DataIC50: 58nMAssay Description:Displacement of [125I]RANTES from human CCR5 receptor co-transfected with Galphai6 in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Roche Palo Alto

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50310740BDBM50310740((S)-5-butyl-9-(1-(2,4-dimethylnicotinoyl)-4-methyl...)
Affinity DataIC50: 61nMAssay Description:Displacement of [125I]RANTES from human CCR5 receptor co-transfected with Galphai6 in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Roche Palo Alto

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50310734BDBM50310734(5-butyl-3-(cyclohexylmethyl)-9-(1-(4,6-dimethylpyr...)
Affinity DataIC50: 68nMAssay Description:Displacement of [125I]RANTES from human CCR5 receptor co-transfected with Galphai6 in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Roche Palo Alto

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50310736BDBM50310736(5-butyl-9-(1-(4,6-dimethylpyrimidine-5-carbonyl)pi...)
Affinity DataIC50: 76nMAssay Description:Displacement of [125I]RANTES from human CCR5 receptor co-transfected with Galphai6 in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Roche Palo Alto

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50310741BDBM50310741((S)-3-(4-(5-butyl-2-oxo-3-((tetrahydro-2H-pyran-4-...)
Affinity DataIC50: 80nMAssay Description:Displacement of [125I]RANTES from human CCR5 receptor co-transfected with Galphai6 in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Roche Palo Alto

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50310735BDBM50310735(5-butyl-9-(1-(2,6-dimethylbenzoyl)piperidin-4-yl)-...)
Affinity DataIC50: 89nMAssay Description:Displacement of [125I]RANTES from human CCR5 receptor co-transfected with Galphai6 in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Roche Palo Alto

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50310745BDBM50310745((S)-5-butyl-9-(1-(4,6-dimethyl-2-(trifluoromethyl)...)
Affinity DataIC50: 97nMAssay Description:Displacement of [125I]RANTES from human CCR5 receptor co-transfected with Galphai6 in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Roche Palo Alto

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50310725BDBM50310725(4-butyl-3-(cyclohexylmethyl)-8-(1-(2-methylbenzoyl...)
Affinity DataIC50: 100nMAssay Description:Displacement of [125I]RANTES from human CCR5 receptor co-transfected with Galphai6 in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Roche Palo Alto

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50310738BDBM50310738((R)-5-butyl-9-(1-(4,6-dimethylpyrimidine-5-carbony...)
Affinity DataIC50: 100nMAssay Description:Displacement of [125I]RANTES from human CCR5 receptor co-transfected with Galphai6 in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Roche Palo Alto

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50310728BDBM50310728(3-benzyl-4-butyl-8-(1-(2,6-dimethylbenzoyl)piperid...)
Affinity DataIC50: 144nMAssay Description:Displacement of [125I]RANTES from human CCR5 receptor co-transfected with Galphai6 in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Roche Palo Alto

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50310729BDBM50310729(3-(cyclohexylmethyl)-8-(1-(2,6-dimethylbenzoyl)pip...)
Affinity DataIC50: 300nMAssay Description:Displacement of [125I]RANTES from human CCR5 receptor co-transfected with Galphai6 in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Roche Palo Alto

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50310739BDBM50310739((S)-5-butyl-9-(1-(4,6-dimethylpyrimidine-5-carbony...)
Affinity DataIC50: 1.19E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Roche Palo Alto

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50310739BDBM50310739((S)-5-butyl-9-(1-(4,6-dimethylpyrimidine-5-carbony...)
Affinity DataIC50: 5.00E+4nMAssay Description:Binding affinity to human CCR2b receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 1(Human)
Roche Palo Alto

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50310739BDBM50310739((S)-5-butyl-9-(1-(4,6-dimethylpyrimidine-5-carbony...)
Affinity DataIC50: 5.00E+4nMAssay Description:Binding affinity to human CCR1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 4(Human)
Roche Palo Alto

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50310739BDBM50310739((S)-5-butyl-9-(1-(4,6-dimethylpyrimidine-5-carbony...)
Affinity DataIC50: 5.00E+4nMAssay Description:Binding affinity to human CXCR4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 6(Human)
Roche Palo Alto

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50310739BDBM50310739((S)-5-butyl-9-(1-(4,6-dimethylpyrimidine-5-carbony...)
Affinity DataIC50: 5.00E+4nMAssay Description:Binding affinity to human CCR6 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 4(Human)
Roche Palo Alto

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50310739BDBM50310739((S)-5-butyl-9-(1-(4,6-dimethylpyrimidine-5-carbony...)
Affinity DataIC50: 5.00E+4nMAssay Description:Binding affinity to human CCR4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 3(Human)
Roche Palo Alto

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50310739BDBM50310739((S)-5-butyl-9-(1-(4,6-dimethylpyrimidine-5-carbony...)
Affinity DataIC50: 5.00E+4nMAssay Description:Binding affinity to human CCR3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed