Compile Data Set for Download or QSAR
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Found 6 Enz. Inhib. hit(s) with all data for entry = 50030721
TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
Nagoya City University

Curated by ChEMBL
LigandPNGBDBM50300464((S)-benzyl 6-ethanethioamido-1-oxo-1-(phenylamino)...)
Affinity DataIC50:  2.70E+3nMAssay Description:Inhibition of human recombinant SIRT1 after 60 mins by fluorimetric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
Nagoya City University

Curated by ChEMBL
LigandPNGBDBM27507(3-Pyridinecarboxamide | CHEMBL1140 | NAM | niacina...)
Affinity DataIC50:  1.10E+4nMAssay Description:Inhibition of human recombinant SIRT2 after 60 mins by fluorimetric analysisMore data for this Ligand-Target Pair
TargetNAD-dependent protein deacetylase sirtuin-3, mitochondrial(Homo sapiens (Human))
Nagoya City University

Curated by ChEMBL
LigandPNGBDBM27507(3-Pyridinecarboxamide | CHEMBL1140 | NAM | niacina...)
Affinity DataIC50:  1.40E+4nMAssay Description:Inhibition of human recombinant SIRT3 after 60 mins by fluorimetric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
Nagoya City University

Curated by ChEMBL
LigandPNGBDBM50300464((S)-benzyl 6-ethanethioamido-1-oxo-1-(phenylamino)...)
Affinity DataIC50:  2.30E+4nMAssay Description:Inhibition of human recombinant SIRT2 after 60 mins by fluorimetric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
Nagoya City University

Curated by ChEMBL
LigandPNGBDBM27507(3-Pyridinecarboxamide | CHEMBL1140 | NAM | niacina...)
Affinity DataIC50:  1.00E+5nMAssay Description:Inhibition of human recombinant SIRT1 after 60 mins by fluorimetric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-3, mitochondrial(Homo sapiens (Human))
Nagoya City University

Curated by ChEMBL
LigandPNGBDBM50300464((S)-benzyl 6-ethanethioamido-1-oxo-1-(phenylamino)...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human recombinant SIRT3 after 60 mins by fluorimetric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed