Compile Data Set for Download or QSAR
Report error Found 45 Enz. Inhib. hit(s) with all data for entry = 50030824
Target5-hydroxytryptamine receptor 2C(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50302140BDBM50302140(2-(2-chlorophenethoxy)-6-(piperazin-1-yl)pyrazine ...)
Affinity DataEC50:  10nMAssay Description:Agonist activity at human recombinant 5HT2C receptor expressed in CHOK1 cells assessed as induction of calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50301772BDBM50301772((R)-6-(2-methylpiperazin-1-yl)-2-(2-(2-(trifluorom...)
Affinity DataEC50:  11nMAssay Description:Agonist activity at human recombinant 5HT2C receptor expressed in CHOK1 cells assessed as induction of calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50302145BDBM50302145((R)-2-(2-(2-chlorophenoxy)ethyl)-6-(2-methylpipera...)
Affinity DataEC50:  25nMAssay Description:Agonist activity at human recombinant 5HT2C receptor expressed in CHOK1 cells assessed as induction of calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50302151BDBM50302151((S)-2-(1-(2-chlorophenoxy)propan-2-yl)-6-(piperazi...)
Affinity DataEC50:  25nMAssay Description:Agonist activity at human recombinant 5HT2C receptor expressed in CHOK1 cells assessed as induction of calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50301772BDBM50301772((R)-6-(2-methylpiperazin-1-yl)-2-(2-(2-(trifluorom...)
Affinity DataEC50:  41nMAssay Description:Agonist activity at human recombinant 5HT2A receptor expressed in Swiss mouse 3T3 cells assessed as induction of calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50302160BDBM50302160(6-(piperazin-1-yl)-2-(2-(2-(trifluoromethyl)phenox...)
Affinity DataEC50:  47nMAssay Description:Agonist activity at human recombinant 5HT2C receptor expressed in CHOK1 cells assessed as induction of calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50302151BDBM50302151((S)-2-(1-(2-chlorophenoxy)propan-2-yl)-6-(piperazi...)
Affinity DataEC50:  65nMAssay Description:Agonist activity at human recombinant 5HT2A receptor expressed in Swiss mouse 3T3 cells assessed as induction of calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50301772BDBM50301772((R)-6-(2-methylpiperazin-1-yl)-2-(2-(2-(trifluorom...)
Affinity DataKi:  89nMAssay Description:Displacement of [3H]meselurgine from human recombinant 5HT2C receptor expressed in Swiss mouse 3T3 cells by SPAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50302162BDBM50302162(2-(2-(2-bromophenoxy)ethyl)-6-(piperazin-1-yl)pyri...)
Affinity DataEC50:  101nMAssay Description:Agonist activity at human recombinant 5HT2C receptor expressed in CHOK1 cells assessed as induction of calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50302145BDBM50302145((R)-2-(2-(2-chlorophenoxy)ethyl)-6-(2-methylpipera...)
Affinity DataEC50:  114nMAssay Description:Agonist activity at human recombinant 5HT2A receptor expressed in Swiss mouse 3T3 cells assessed as induction of calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50302158BDBM50302158(2-(2-(6-oxo-3-(piperazin-1-yl)pyridazin-1(6H)-yl)e...)
Affinity DataEC50:  114nMAssay Description:Agonist activity at human recombinant 5HT2C receptor expressed in CHOK1 cells assessed as induction of calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50001915BDBM50001915(mCPP | 1-(3-chlorophenyl)piperazine | CHEMBL478 | ...)
Affinity DataEC50:  125nMAssay Description:Agonist activity at human recombinant 5HT2B receptor expressed in Swiss mouse 3T3 cells assessed as induction of calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50302141BDBM50302141(2-(2-(2-chlorophenoxy)ethyl)-6-(piperazin-1-yl)pyr...)
Affinity DataEC50:  164nMAssay Description:Agonist activity at human recombinant 5HT2C receptor expressed in CHOK1 cells assessed as induction of calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50001915BDBM50001915(mCPP | 1-(3-chlorophenyl)piperazine | CHEMBL478 | ...)
Affinity DataEC50:  167nMAssay Description:Agonist activity at human recombinant 5HT2A receptor expressed in Swiss mouse 3T3 cells assessed as induction of calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50001915BDBM50001915(mCPP | 1-(3-chlorophenyl)piperazine | CHEMBL478 | ...)
Affinity DataEC50:  170nMAssay Description:Agonist activity at human recombinant 5HT2C receptor expressed in CHOK1 cells assessed as induction of calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50302140BDBM50302140(2-(2-chlorophenethoxy)-6-(piperazin-1-yl)pyrazine ...)
Affinity DataEC50:  187nMAssay Description:Agonist activity at human recombinant 5HT2B receptor expressed in Swiss mouse 3T3 cells assessed as induction of calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50302141BDBM50302141(2-(2-(2-chlorophenoxy)ethyl)-6-(piperazin-1-yl)pyr...)
Affinity DataEC50:  254nMAssay Description:Agonist activity at human recombinant 5HT2A receptor expressed in Swiss mouse 3T3 cells assessed as induction of calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50302140BDBM50302140(2-(2-chlorophenethoxy)-6-(piperazin-1-yl)pyrazine ...)
Affinity DataEC50:  308nMAssay Description:Agonist activity at human recombinant 5HT2A receptor expressed in Swiss mouse 3T3 cells assessed as induction of calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50302145BDBM50302145((R)-2-(2-(2-chlorophenoxy)ethyl)-6-(2-methylpipera...)
Affinity DataKi:  325nMAssay Description:Displacement of [3H]meselurgine from human recombinant 5HT2C receptor expressed in Swiss mouse 3T3 cells by SPAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50302153BDBM50302153((S)-2-(2-(2-chlorophenoxy)propyl)-6-(piperazin-1-y...)
Affinity DataEC50:  360nMAssay Description:Agonist activity at human recombinant 5HT2C receptor expressed in CHOK1 cells assessed as induction of calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50302147BDBM50302147((R)-2-(2-(2-chlorophenoxy)ethyl)-6-(2-ethylpiperaz...)
Affinity DataEC50:  407nMAssay Description:Agonist activity at human recombinant 5HT2C receptor expressed in CHOK1 cells assessed as induction of calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50302160BDBM50302160(6-(piperazin-1-yl)-2-(2-(2-(trifluoromethyl)phenox...)
Affinity DataKi:  424nMAssay Description:Displacement of [3H]meselurgine from human recombinant 5HT2C receptor expressed in Swiss mouse 3T3 cells by SPAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50302151BDBM50302151((S)-2-(1-(2-chlorophenoxy)propan-2-yl)-6-(piperazi...)
Affinity DataEC50:  506nMAssay Description:Agonist activity at human recombinant 5HT2B receptor expressed in Swiss mouse 3T3 cells assessed as induction of calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50302144BDBM50302144(2-(2-(2-chlorophenoxy)ethyl)-5-methyl-6-(piperazin...)
Affinity DataEC50:  510nMAssay Description:Agonist activity at human recombinant 5HT2C receptor expressed in CHOK1 cells assessed as induction of calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50302151BDBM50302151((S)-2-(1-(2-chlorophenoxy)propan-2-yl)-6-(piperazi...)
Affinity DataKi:  728nMAssay Description:Displacement of [3H]meselurgine from human recombinant 5HT2C receptor expressed in Swiss mouse 3T3 cells by SPAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50302152BDBM50302152((R)-2-(2-(2-chlorophenoxy)propyl)-6-(piperazin-1-y...)
Affinity DataEC50:  858nMAssay Description:Agonist activity at human recombinant 5HT2C receptor expressed in CHOK1 cells assessed as induction of calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50302160BDBM50302160(6-(piperazin-1-yl)-2-(2-(2-(trifluoromethyl)phenox...)
Affinity DataEC50:  1.09E+3nMAssay Description:Agonist activity at human recombinant 5HT2A receptor expressed in Swiss mouse 3T3 cells assessed as induction of calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50302141BDBM50302141(2-(2-(2-chlorophenoxy)ethyl)-6-(piperazin-1-yl)pyr...)
Affinity DataKi:  1.60E+3nMAssay Description:Displacement of [3H]meselurgine from human recombinant 5HT2C receptor expressed in Swiss mouse 3T3 cells by SPAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50302150BDBM50302150((R)-2-(1-(2-chlorophenoxy)propan-2-yl)-6-(piperazi...)
Affinity DataEC50: >1.92E+3nMAssay Description:Agonist activity at human recombinant 5HT2C receptor expressed in CHOK1 cells assessed as induction of calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50302157BDBM50302157(2-(2-(2,3-dichlorophenoxy)ethyl)-6-(piperazin-1-yl...)
Affinity DataEC50: >2.13E+3nMAssay Description:Agonist activity at human recombinant 5HT2C receptor expressed in CHOK1 cells assessed as induction of calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50301772BDBM50301772((R)-6-(2-methylpiperazin-1-yl)-2-(2-(2-(trifluorom...)
Affinity DataEC50: >2.61E+3nMAssay Description:Agonist activity at human recombinant 5HT2B receptor expressed in Swiss mouse 3T3 cells assessed as induction of calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50301772BDBM50301772((R)-6-(2-methylpiperazin-1-yl)-2-(2-(2-(trifluorom...)
Affinity DataIC50: 3.70E+3nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50302159BDBM50302159(6-(piperazin-1-yl)-2-(2-(o-tolyloxy)ethyl)pyridazi...)
Affinity DataEC50: >4.55E+3nMAssay Description:Agonist activity at human recombinant 5HT2C receptor expressed in CHOK1 cells assessed as induction of calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50302148BDBM50302148(1-(1-(2-(2-chlorophenoxy)ethyl)-6-oxo-1,6-dihydrop...)
Affinity DataEC50: >9.98E+3nMAssay Description:Agonist activity at human recombinant 5HT2C receptor expressed in CHOK1 cells assessed as induction of calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50302146BDBM50302146((S)-2-(2-(2-chlorophenoxy)ethyl)-6-(2-methylpipera...)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human recombinant 5HT2C receptor expressed in CHOK1 cells assessed as induction of calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50302161BDBM50302161(2-(2-(2-methoxyphenoxy)ethyl)-6-(piperazin-1-yl)py...)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human recombinant 5HT2C receptor expressed in CHOK1 cells assessed as induction of calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50302143BDBM50302143(2-(2-(2-chlorophenoxy)ethyl)-4-(piperazin-1-yl)-2,...)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human recombinant 5HT2C receptor expressed in CHOK1 cells assessed as induction of calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50302149BDBM50302149((S)-2-(2-(2-chlorophenoxy)ethyl)-6-(3-methylpipera...)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human recombinant 5HT2C receptor expressed in CHOK1 cells assessed as induction of calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50302145BDBM50302145((R)-2-(2-(2-chlorophenoxy)ethyl)-6-(2-methylpipera...)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human recombinant 5HT2B receptor expressed in Swiss mouse 3T3 cells assessed as induction of calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50302154BDBM50302154(2-(2-(4-chlorophenoxy)ethyl)-6-(piperazin-1-yl)pyr...)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human recombinant 5HT2C receptor expressed in CHOK1 cells assessed as induction of calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50302141BDBM50302141(2-(2-(2-chlorophenoxy)ethyl)-6-(piperazin-1-yl)pyr...)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human recombinant 5HT2B receptor expressed in Swiss mouse 3T3 cells assessed as induction of calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50302142BDBM50302142(2-(2-(2-chlorophenoxy)ethyl)-4-methyl-6-(piperazin...)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human recombinant 5HT2C receptor expressed in CHOK1 cells assessed as induction of calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50302160BDBM50302160(6-(piperazin-1-yl)-2-(2-(2-(trifluoromethyl)phenox...)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human recombinant 5HT2B receptor expressed in Swiss mouse 3T3 cells assessed as induction of calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50302156BDBM50302156(2-(2-phenoxyethyl)-6-(piperazin-1-yl)pyridazin-3(2...)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human recombinant 5HT2C receptor expressed in CHOK1 cells assessed as induction of calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50302155BDBM50302155(2-(2-(3-chlorophenoxy)ethyl)-6-(piperazin-1-yl)pyr...)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human recombinant 5HT2C receptor expressed in CHOK1 cells assessed as induction of calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed