Compile Data Set for Download or QSAR
Report error Found 76 Enz. Inhib. hit(s) with all data for entry = 50031310
TargetTelomerase reverse transcriptase(Human)
Central University of Las Villas

Curated by ChEMBL
LigandPNGBDBM50134027(N-[9-(2-Dimethylamino-ethylamino)-6-(3-pyrrolidin-...)
Affinity DataIC50: 18nMAssay Description:Inhibition of telomerase in human A2780 cells by TRAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetTelomerase reverse transcriptase(Human)
Central University of Las Villas

Curated by ChEMBL
LigandPNGBDBM50310892(N,N'-(9-(2-(1-methylpyrrolidin-2-yl)ethylamino)acr...)
Affinity DataIC50: 18nMAssay Description:Inhibition of telomerase in human A2780 cells by TRAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetTelomerase reverse transcriptase(Human)
Central University of Las Villas

Curated by ChEMBL
LigandPNGBDBM50134010(N-[9-(2-Amino-phenylamino)-6-(3-pyrrolidin-1-yl-pr...)
Affinity DataIC50: 20nMAssay Description:Inhibition of telomerase in human A2780 cells by TRAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetTelomerase reverse transcriptase(Human)
Central University of Las Villas

Curated by ChEMBL
LigandPNGBDBM50134022(N,N'-(9-(4-acetylphenylamino)acridine-3,6-diyl)bis...)
Affinity DataIC50: 40nMAssay Description:Inhibition of telomerase in human A2780 cells by TRAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetTelomerase reverse transcriptase(Human)
Central University of Las Villas

Curated by ChEMBL
LigandPNGBDBM50134002(N-[9-(2-Piperidin-1-yl-ethylamino)-6-(3-pyrrolidin...)
Affinity DataIC50: 50nMAssay Description:Inhibition of telomerase in human A2780 cells by TRAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetTelomerase reverse transcriptase(Human)
Central University of Las Villas

Curated by ChEMBL
LigandPNGBDBM50134032(N,N'-(9-(cyclopropylamino)acridine-3,6-diyl)bis(3-...)
Affinity DataIC50: 50nMAssay Description:Inhibition of telomerase in human A2780 cells by TRAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetTelomerase reverse transcriptase(Human)
Central University of Las Villas

Curated by ChEMBL
LigandPNGBDBM50134019(N,N'-(9-(3-aminophenylamino)acridine-3,6-diyl)bis(...)
Affinity DataIC50: 60nMAssay Description:Inhibition of telomerase in human A2780 cells by TRAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetTelomerase reverse transcriptase(Human)
Central University of Las Villas

Curated by ChEMBL
LigandPNGBDBM50134009(N,N'-(9-(3-(dimethylamino)propylamino)acridine-3,6...)
Affinity DataIC50: 60nMAssay Description:Inhibition of telomerase in human A2780 cells by TRAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetTelomerase reverse transcriptase(Human)
Central University of Las Villas

Curated by ChEMBL
LigandPNGBDBM50134025(N-[9-(4-Fluoro-phenylamino)-6-(3-pyrrolidin-1-yl-p...)
Affinity DataIC50: 70nMAssay Description:Inhibition of telomerase in human A2780 cells by TRAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetTelomerase reverse transcriptase(Human)
Central University of Las Villas

Curated by ChEMBL
LigandPNGBDBM50134018(N-[9-(4-Amino-phenylamino)-6-(3-pyrrolidin-1-yl-pr...)
Affinity DataIC50: 74nMAssay Description:Inhibition of telomerase in human A2780 cells by TRAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetTelomerase reverse transcriptase(Human)
Central University of Las Villas

Curated by ChEMBL
LigandPNGBDBM50134023(N,N'-(9-(4-aminophenylamino)acridine-2,6-diyl)bis(...)
Affinity DataIC50: 80nMAssay Description:Inhibition of telomerase in human A2780 cells by TRAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetTelomerase reverse transcriptase(Human)
Central University of Las Villas

Curated by ChEMBL
LigandPNGBDBM50134008(N-[9-(3-Dimethylamino-propylamino)-6-(3-pyrrolidin...)
Affinity DataIC50: 80nMAssay Description:Inhibition of telomerase in human A2780 cells by TRAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetTelomerase reverse transcriptase(Human)
Central University of Las Villas

Curated by ChEMBL
LigandPNGBDBM50150618(N1-(4-(3,6-bis(3-(pyrrolidin-1-yl)propanamido)acri...)
Affinity DataIC50: 80nMAssay Description:Inhibition of telomerase in human A2780 cells by TRAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetTelomerase reverse transcriptase(Human)
Central University of Las Villas

Curated by ChEMBL
LigandPNGBDBM50134000(N,N'-(9-(cyclohexylamino)acridine-3,6-diyl)bis(3-(...)
Affinity DataIC50: 90nMAssay Description:Inhibition of telomerase in human A2780 cells by TRAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetTelomerase reverse transcriptase(Human)
Central University of Las Villas

Curated by ChEMBL
LigandPNGBDBM50150622(N1-(4-(3,6-bis(3-(pyrrolidin-1-yl)propanamido)acri...)
Affinity DataIC50: 98nMAssay Description:Inhibition of telomerase in human A2780 cells by TRAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetTelomerase reverse transcriptase(Human)
Central University of Las Villas

Curated by ChEMBL
LigandPNGBDBM50134021(N-[9-(3-Methylsulfanyl-phenylamino)-6-(3-pyrrolidi...)
Affinity DataIC50: 100nMAssay Description:Inhibition of telomerase in human A2780 cells by TRAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetTelomerase reverse transcriptase(Human)
Central University of Las Villas

Curated by ChEMBL
LigandPNGBDBM50134030(N,N'-(9-{[4-(dimethylamino)phenyl]amino}acridine-3...)
Affinity DataIC50: 100nMAssay Description:Inhibition of telomerase in human A2780 cells by TRAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetTelomerase reverse transcriptase(Human)
Central University of Las Villas

Curated by ChEMBL
LigandPNGBDBM50134026(N,N'-(9-(3-(dimethylamino)phenylamino)acridine-3,6...)
Affinity DataIC50: 100nMAssay Description:Inhibition of telomerase in human A2780 cells by TRAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetTelomerase reverse transcriptase(Human)
Central University of Las Villas

Curated by ChEMBL
LigandPNGBDBM50134020(N,N'-(9-(3-acetamidophenylamino)acridine-3,6-diyl)...)
Affinity DataIC50: 100nMAssay Description:Inhibition of telomerase in human A2780 cells by TRAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetTelomerase reverse transcriptase(Human)
Central University of Las Villas

Curated by ChEMBL
LigandPNGBDBM50134011(N-[9-(2-Amino-phenylamino)-6-(3-pyrrolidin-1-yl-pr...)
Affinity DataIC50: 110nMAssay Description:Inhibition of telomerase in human A2780 cells by TRAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetTelomerase reverse transcriptase(Human)
Central University of Las Villas

Curated by ChEMBL
LigandPNGBDBM50134006(N-[9-(2-Methoxy-ethylamino)-6-(3-pyrrolidin-1-yl-p...)
Affinity DataIC50: 140nMAssay Description:Inhibition of telomerase in human A2780 cells by TRAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetTelomerase reverse transcriptase(Human)
Central University of Las Villas

Curated by ChEMBL
LigandPNGBDBM50133998(N-[9-(2-Methylsulfanyl-phenylamino)-6-(3-pyrrolidi...)
Affinity DataIC50: 150nMAssay Description:Inhibition of telomerase in human A2780 cells by TRAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetTelomerase reverse transcriptase(Human)
Central University of Las Villas

Curated by ChEMBL
LigandPNGBDBM50134017(N,N'-(9-(4-(dimethylamino)phenylamino)acridine-2,6...)
Affinity DataIC50: 170nMAssay Description:Inhibition of telomerase in human A2780 cells by TRAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetTelomerase reverse transcriptase(Human)
Central University of Las Villas

Curated by ChEMBL
LigandPNGBDBM50133999(N-[9-(2-Amino-phenylamino)-7-(3-pyrrolidin-1-yl-pr...)
Affinity DataIC50: 170nMAssay Description:Inhibition of telomerase in human A2780 cells by TRAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetTelomerase reverse transcriptase(Human)
Central University of Las Villas

Curated by ChEMBL
LigandPNGBDBM50310879(N,N'-(9-oxo-9,9a-dihydroacridine-2,6-diyl)bis(3-(2...)
Affinity DataIC50: 200nMAssay Description:Inhibition of telomerase in human A2780 cells by TRAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetTelomerase reverse transcriptase(Human)
Central University of Las Villas

Curated by ChEMBL
LigandPNGBDBM50155646(CHEMBL186346 | CHEMBL1079146 | 3-(4-Hydroxy-piperi...)
Affinity DataIC50: 200nMAssay Description:Inhibition of telomerase in human A2780 cells by TRAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetTelomerase reverse transcriptase(Human)
Central University of Las Villas

Curated by ChEMBL
LigandPNGBDBM50155661(CHEMBL1078040 | CHEMBL361868 | 3-(4-Methyl-piperid...)
Affinity DataIC50: 200nMAssay Description:Inhibition of telomerase in human A2780 cells by TRAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetTelomerase reverse transcriptase(Human)
Central University of Las Villas

Curated by ChEMBL
LigandPNGBDBM50134028(N-[9-(4-Amino-phenylamino)-7-(3-pyrrolidin-1-yl-pr...)
Affinity DataIC50: 200nMAssay Description:Inhibition of telomerase in human A2780 cells by TRAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetTelomerase reverse transcriptase(Human)
Central University of Las Villas

Curated by ChEMBL
LigandPNGBDBM50134012(N-[9-(3-Amino-phenylamino)-6-(3-pyrrolidin-1-yl-pr...)
Affinity DataIC50: 210nMAssay Description:Inhibition of telomerase in human A2780 cells by TRAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetTelomerase reverse transcriptase(Human)
Central University of Las Villas

Curated by ChEMBL
LigandPNGBDBM50134031(N-[9-Cyclohexylamino-6-(3-pyrrolidin-1-yl-propiony...)
Affinity DataIC50: 210nMAssay Description:Inhibition of telomerase in human A2780 cells by TRAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetTelomerase reverse transcriptase(Human)
Central University of Las Villas

Curated by ChEMBL
LigandPNGBDBM50310884(N,N'-(9-(cycloheptylamino)acridine-3,6-diyl)bis(3-...)
Affinity DataIC50: 210nMAssay Description:Inhibition of telomerase in human A2780 cells by TRAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetTelomerase reverse transcriptase(Human)
Central University of Las Villas

Curated by ChEMBL
LigandPNGBDBM50310886(1-(6-(4-(3,6-bis(3-(pyrrolidin-1-yl)propanamido)ac...)
Affinity DataIC50: 267nMAssay Description:Inhibition of telomerase in human A2780 cells by TRAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetTelomerase reverse transcriptase(Human)
Central University of Las Villas

Curated by ChEMBL
LigandPNGBDBM50134001(N-[9-(2-Dimethylamino-ethylamino)-6-(3-pyrrolidin-...)
Affinity DataIC50: 270nMAssay Description:Inhibition of telomerase in human A2780 cells by TRAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetTelomerase reverse transcriptase(Human)
Central University of Las Villas

Curated by ChEMBL
LigandPNGBDBM50150621(6-Oxo-6-pyrrolidin-1-yl-hexanoic acid {4-[3,6-bis-...)
Affinity DataIC50: 318nMAssay Description:Inhibition of telomerase in human A2780 cells by TRAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetTelomerase reverse transcriptase(Human)
Central University of Las Villas

Curated by ChEMBL
LigandPNGBDBM50155667(CHEMBL186019 | CHEMBL1077951 | N-[9-Oxo-6-(3-piper...)
Affinity DataIC50: 400nMAssay Description:Inhibition of telomerase in human A2780 cells by TRAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetTelomerase reverse transcriptase(Human)
Central University of Las Villas

Curated by ChEMBL
LigandPNGBDBM50134003(N,N'-(9-(4-methoxyphenylamino)acridine-2,7-diyl)bi...)
Affinity DataIC50: 460nMAssay Description:Inhibition of telomerase in human A2780 cells by TRAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetTelomerase reverse transcriptase(Human)
Central University of Las Villas

Curated by ChEMBL
LigandPNGBDBM50134013(N-[9-(4-Dimethylamino-phenylamino)-7-(3-pyrrolidin...)
Affinity DataIC50: 500nMAssay Description:Inhibition of telomerase in human A2780 cells by TRAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetTelomerase reverse transcriptase(Human)
Central University of Las Villas

Curated by ChEMBL
LigandPNGBDBM50134005(N-[9-(2-Dimethylamino-ethylamino)-7-(3-pyrrolidin-...)
Affinity DataIC50: 570nMAssay Description:Inhibition of telomerase in human A2780 cells by TRAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetTelomerase reverse transcriptase(Human)
Central University of Las Villas

Curated by ChEMBL
LigandPNGBDBM50155645(CHEMBL186971 | CHEMBL1078925 | 3-Dimethylamino-N-[...)
Affinity DataIC50: 600nMAssay Description:Inhibition of telomerase in human A2780 cells by TRAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetTelomerase reverse transcriptase(Human)
Central University of Las Villas

Curated by ChEMBL
LigandPNGBDBM50134033(N,N'-(9-(3-(dimethylamino)phenylamino)acridine-2,7...)
Affinity DataIC50: 600nMAssay Description:Inhibition of telomerase in human A2780 cells by TRAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetTelomerase reverse transcriptase(Human)
Central University of Las Villas

Curated by ChEMBL
LigandPNGBDBM50155655(CHEMBL1077950 | CHEMBL186933 | 3-Diethylamino-N-[6...)
Affinity DataIC50: 700nMAssay Description:Inhibition of telomerase in human A2780 cells by TRAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetTelomerase reverse transcriptase(Human)
Central University of Las Villas

Curated by ChEMBL
LigandPNGBDBM50134014(N,N'-(9-(2-hydroxyphenylamino)acridine-2,7-diyl)bi...)
Affinity DataIC50: 1.03E+3nMAssay Description:Inhibition of telomerase in human A2780 cells by TRAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetTelomerase reverse transcriptase(Human)
Central University of Las Villas

Curated by ChEMBL
LigandPNGBDBM50134024(N,N'-(9-(3-aminophenylamino)acridine-2,7-diyl)bis(...)
Affinity DataIC50: 1.09E+3nMAssay Description:Inhibition of telomerase in human A2780 cells by TRAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetTelomerase reverse transcriptase(Human)
Central University of Las Villas

Curated by ChEMBL
LigandPNGBDBM50134029(N,N'-(9-(phenylamino)acridine-2,7-diyl)bis(3-(pyrr...)
Affinity DataIC50: 1.29E+3nMAssay Description:Inhibition of telomerase in human A2780 cells by TRAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetTelomerase reverse transcriptase(Human)
Central University of Las Villas

Curated by ChEMBL
LigandPNGBDBM50134004(N,N'-(9-(phenylamino)acridine-2,6-diyl)bis(3-(pyrr...)
Affinity DataIC50: 1.33E+3nMAssay Description:Inhibition of telomerase in human A2780 cells by TRAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetTelomerase reverse transcriptase(Human)
Central University of Las Villas

Curated by ChEMBL
LigandPNGBDBM50080842(N,N'-(acridine-3,6-diyl)bis(3-(4-methylpiperidin-1...)
Affinity DataIC50: 1.35E+3nMAssay Description:Inhibition of telomerase in human A2780 cells by TRAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetTelomerase reverse transcriptase(Human)
Central University of Las Villas

Curated by ChEMBL
LigandPNGBDBM50155658(CHEMBL1076521 | CHEMBL186848 | 3-(2-Methyl-piperid...)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of telomerase in human A2780 cells by TRAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetTelomerase reverse transcriptase(Human)
Central University of Las Villas

Curated by ChEMBL
LigandPNGBDBM50155647(CHEMBL184711 | CHEMBL1080613 | 3-(4-Methyl-piperid...)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of telomerase in human A2780 cells by TRAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetTelomerase reverse transcriptase(Human)
Central University of Las Villas

Curated by ChEMBL
LigandPNGBDBM50155663(CHEMBL365070 | CHEMBL1079899 | 3-(4-Hydroxy-piperi...)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of telomerase in human A2780 cells by TRAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetTelomerase reverse transcriptase(Human)
Central University of Las Villas

Curated by ChEMBL
LigandPNGBDBM50310876(1,1'-(3,3'-(9-oxo-8a,9-dihydroacridine-2,7-diyl)bi...)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of telomerase in human A2780 cells by TRAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
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