Compile Data Set for Download or QSAR
Report error Found 31 Enz. Inhib. hit(s) with all data for entry = 50031345
TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50311624BDBM50311624(3,4-difluoro-N-(5-(5-fluoro-3-methyl-1-(naphthalen...)
Affinity DataIC50: 1nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50311615BDBM50311615(4,5-dichloro-N-(5-(5-fluoro-3-methyl-1-(naphthalen...)
Affinity DataIC50: 1nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50311623BDBM50311623(N-(5-(1-(2,4-dichlorobenzyl)-5-fluoro-3-methyl-1H-...)
Affinity DataIC50: 1nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50311621BDBM50311621(3,4-dichloro-N-(5-(1-(2,4-dichlorobenzyl)-5-fluoro...)
Affinity DataIC50: 1nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50311610BDBM50311610(4,5-dichloro-N-(5-(1-(2,4-dichlorobenzyl)-5-fluoro...)
Affinity DataIC50: 2nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50311619BDBM50311619(N-(5-(1-(2,4-dichlorobenzyl)-5-fluoro-3-methyl-1H-...)
Affinity DataIC50: 2nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50311618BDBM50311618(N-(5-(1-(2,4-dichlorobenzyl)-5-fluoro-3-methyl-1H-...)
Affinity DataIC50: 3nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50311622BDBM50311622(3,4-dichloro-N-(5-(1-(2,4-dichlorobenzyl)-5-fluoro...)
Affinity DataIC50: 4nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50303662BDBM50303662(3-(1-(2,4-dichlorobenzyl)-5-fluoro-3-methyl-1H-ind...)
Affinity DataIC50: 4.60nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50311614BDBM50311614(4,5-dichloro-N-(5-(1-(2,4-dichlorobenzyl)-5-fluoro...)
Affinity DataIC50: 5nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50311617BDBM50311617(2,4,5-trifluoro-N-(5-(5-fluoro-3-methyl-1-(naphtha...)
Affinity DataIC50: 8nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50311611BDBM50311611(4,5-dichloro-N-(5-(1-(2,4-dichlorobenzyl)-5-fluoro...)
Affinity DataIC50: 10nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50311620BDBM50311620(3,4-dichloro-N-(5-(5-fluoro-3-methyl-1-(naphthalen...)
Affinity DataIC50: 11nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50311626BDBM50311626(N-(5-(1-(3,4-difluorobenzyl)-5-fluoro-3-methyl-1H-...)
Affinity DataIC50: 12nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50311625BDBM50311625(N-(5-(1-(2,4-dichlorobenzyl)-5-fluoro-3-methyl-1H-...)
Affinity DataIC50: 20nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50311612BDBM50311612(4,5-dichloro-N-(5-(1-(2,4-dichlorobenzyl)-5-fluoro...)
Affinity DataIC50: 24nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50311627BDBM50311627(N-(5-(1-(3,4-difluorobenzyl)-5-fluoro-3-methyl-1H-...)
Affinity DataIC50: 44nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50311613BDBM50311613(4,5-dichloro-N-(5-(1-(3,4-difluorobenzyl)-5-fluoro...)
Affinity DataIC50: 59nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50311632BDBM50311632(N-(5-(1-(2,4-dichlorobenzyl)-5-fluoro-3-methyl-1H-...)
Affinity DataIC50: 244nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50311631BDBM50311631(N-(5-(1-(2,4-dichlorobenzyl)-5-fluoro-3-methyl-1H-...)
Affinity DataIC50: 363nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetProstaglandin F2-alpha receptor(Human)
Decode Chemistry

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50311623BDBM50311623(N-(5-(1-(2,4-dichlorobenzyl)-5-fluoro-3-methyl-1H-...)
Affinity DataIC50: 600nMAssay Description:Binding affinity to human FP receptor by radioligand displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50311628BDBM50311628(N-(5-(1-(2,4-dichlorobenzyl)-5-fluoro-3-methyl-1H-...)
Affinity DataIC50: 664nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50311630BDBM50311630(N-(5-(1-(2,4-dichlorobenzyl)-5-fluoro-3-methyl-1H-...)
Affinity DataIC50: 1.02E+3nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50311629BDBM50311629(2,4-dichloro-N-(5-(1-(2,4-dichlorobenzyl)-5-fluoro...)
Affinity DataIC50: 1.32E+3nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50311616BDBM50311616(4,5-dichloro-N-(5-(1-(3,4-difluorobenzyl)-5-fluoro...)
Affinity DataIC50: 1.98E+3nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50311633BDBM50311633(N-(5-(1-(2,4-dichlorobenzyl)-5-fluoro-3-methyl-1H-...)
Affinity DataIC50: 2.57E+3nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50311634BDBM50311634(N-(3-(1-(2,4-difluorobenzyl)-5-fluoro-3-methyl-1H-...)
Affinity DataIC50: 1.79E+4nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP4 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50311623BDBM50311623(N-(5-(1-(2,4-dichlorobenzyl)-5-fluoro-3-methyl-1H-...)
Affinity DataIC50: 1.86E+4nMAssay Description:Binding affinity to human EP4 receptor by radioligand displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP2 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50311623BDBM50311623(N-(5-(1-(2,4-dichlorobenzyl)-5-fluoro-3-methyl-1H-...)
Affinity DataIC50: 1.98E+4nMAssay Description:Binding affinity to human EP2 receptor by radioligand displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetProstacyclin receptor(Human)
Decode Chemistry

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50311623BDBM50311623(N-(5-(1-(2,4-dichlorobenzyl)-5-fluoro-3-methyl-1H-...)
Affinity DataIC50: 2.00E+4nMAssay Description:Binding affinity to human IP receptor by radioligand displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP1 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50311623BDBM50311623(N-(5-(1-(2,4-dichlorobenzyl)-5-fluoro-3-methyl-1H-...)
Affinity DataIC50: 2.00E+4nMAssay Description:Binding affinity to human EP1 receptor by radioligand displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed