Compile Data Set for Download or QSAR
maximum 50k data
Found 52 Enz. Inhib. hit(s) with all data for entry = 50030678
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hanmi Research Center

Curated by ChEMBL
LigandPNGBDBM50300027((S)-1-Acryloyl-N-[4-(3-chloro-2,4-difluorophenylam...)
Affinity DataIC50:  9nMAssay Description:Inhibition of Her1 by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hanmi Research Center

Curated by ChEMBL
LigandPNGBDBM50300026((S)-1-Acryloyl-N-[4-(3-chloro-2-fluorophenylamino)...)
Affinity DataIC50:  13nMAssay Description:Inhibition of Her1 by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Hanmi Research Center

Curated by ChEMBL
LigandPNGBDBM50300027((S)-1-Acryloyl-N-[4-(3-chloro-2,4-difluorophenylam...)
Affinity DataIC50:  18nMAssay Description:Inhibition of Her2 by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Hanmi Research Center

Curated by ChEMBL
LigandPNGBDBM5445(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Affinity DataIC50:  36nMAssay Description:Inhibition of Her2 by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Hanmi Research Center

Curated by ChEMBL
LigandPNGBDBM50300026((S)-1-Acryloyl-N-[4-(3-chloro-2-fluorophenylamino)...)
Affinity DataIC50:  42nMAssay Description:Inhibition of Her2 by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hanmi Research Center

Curated by ChEMBL
LigandPNGBDBM5445(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Affinity DataIC50:  52nMAssay Description:Inhibition of Her1 by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetReceptor tyrosine-protein kinase erbB-4(Homo sapiens (Human))
Hanmi Research Center

Curated by ChEMBL
LigandPNGBDBM50300027((S)-1-Acryloyl-N-[4-(3-chloro-2,4-difluorophenylam...)
Affinity DataIC50: <100nMAssay Description:Inhibition of Her4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Hanmi Research Center

Curated by ChEMBL
LigandPNGBDBM50300027((S)-1-Acryloyl-N-[4-(3-chloro-2,4-difluorophenylam...)
Affinity DataIC50: <100nMAssay Description:Inhibition of LckMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Hanmi Research Center

Curated by ChEMBL
LigandPNGBDBM50300027((S)-1-Acryloyl-N-[4-(3-chloro-2,4-difluorophenylam...)
Affinity DataIC50: <100nMAssay Description:Inhibition of Abl1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Hanmi Research Center

Curated by ChEMBL
LigandPNGBDBM50300027((S)-1-Acryloyl-N-[4-(3-chloro-2,4-difluorophenylam...)
Affinity DataIC50: <100nMAssay Description:Inhibition of SrcMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
Hanmi Research Center

Curated by ChEMBL
LigandPNGBDBM50300027((S)-1-Acryloyl-N-[4-(3-chloro-2,4-difluorophenylam...)
Affinity DataIC50: <100nMAssay Description:Inhibition of RetMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-4(Homo sapiens (Human))
Hanmi Research Center

Curated by ChEMBL
LigandPNGBDBM50300026((S)-1-Acryloyl-N-[4-(3-chloro-2-fluorophenylamino)...)
Affinity DataIC50: <100nMAssay Description:Inhibition of Her4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Hanmi Research Center

Curated by ChEMBL
LigandPNGBDBM50300026((S)-1-Acryloyl-N-[4-(3-chloro-2-fluorophenylamino)...)
Affinity DataIC50:  300nMAssay Description:Inhibition of LckMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Hanmi Research Center

Curated by ChEMBL
LigandPNGBDBM50300026((S)-1-Acryloyl-N-[4-(3-chloro-2-fluorophenylamino)...)
Affinity DataIC50:  500nMAssay Description:Inhibition of Abl1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Hanmi Research Center

Curated by ChEMBL
LigandPNGBDBM50300027((S)-1-Acryloyl-N-[4-(3-chloro-2,4-difluorophenylam...)
Affinity DataIC50:  600nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
Hanmi Research Center

Curated by ChEMBL
LigandPNGBDBM50300026((S)-1-Acryloyl-N-[4-(3-chloro-2-fluorophenylamino)...)
Affinity DataIC50:  700nMAssay Description:Inhibition of RetMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Hanmi Research Center

Curated by ChEMBL
LigandPNGBDBM50300026((S)-1-Acryloyl-N-[4-(3-chloro-2-fluorophenylamino)...)
Affinity DataIC50:  800nMAssay Description:Inhibition of SrcMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Hanmi Research Center

Curated by ChEMBL
LigandPNGBDBM5446(CHEMBL553 | ERLOTINIB HYDROCHLORIDE | Erlotinib | ...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of Her2 by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hanmi Research Center

Curated by ChEMBL
LigandPNGBDBM5446(CHEMBL553 | ERLOTINIB HYDROCHLORIDE | Erlotinib | ...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of Her1 by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Hanmi Research Center

Curated by ChEMBL
LigandPNGBDBM50300026((S)-1-Acryloyl-N-[4-(3-chloro-2-fluorophenylamino)...)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Hanmi Research Center

Curated by ChEMBL
LigandPNGBDBM50300027((S)-1-Acryloyl-N-[4-(3-chloro-2,4-difluorophenylam...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of FGFR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 3(Homo sapiens (Human))
Hanmi Research Center

Curated by ChEMBL
LigandPNGBDBM50300026((S)-1-Acryloyl-N-[4-(3-chloro-2-fluorophenylamino)...)
Affinity DataIC50:  2.70E+3nMAssay Description:Inhibition of Flt4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Hanmi Research Center

Curated by ChEMBL
LigandPNGBDBM50300026((S)-1-Acryloyl-N-[4-(3-chloro-2-fluorophenylamino)...)
Affinity DataIC50:  4.10E+3nMAssay Description:Inhibition of FGFR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 3(Homo sapiens (Human))
Hanmi Research Center

Curated by ChEMBL
LigandPNGBDBM50300027((S)-1-Acryloyl-N-[4-(3-chloro-2,4-difluorophenylam...)
Affinity DataIC50:  4.50E+3nMAssay Description:Inhibition of Flt4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C alpha type(Homo sapiens (Human))
Hanmi Research Center

Curated by ChEMBL
LigandPNGBDBM50300026((S)-1-Acryloyl-N-[4-(3-chloro-2-fluorophenylamino)...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of PKCalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase B(Homo sapiens (Human))
Hanmi Research Center

Curated by ChEMBL
LigandPNGBDBM50300026((S)-1-Acryloyl-N-[4-(3-chloro-2-fluorophenylamino)...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of Aurora BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C alpha type(Homo sapiens (Human))
Hanmi Research Center

Curated by ChEMBL
LigandPNGBDBM50300027((S)-1-Acryloyl-N-[4-(3-chloro-2,4-difluorophenylam...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of PKCalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 1(Homo sapiens (Human))
Hanmi Research Center

Curated by ChEMBL
LigandPNGBDBM50300027((S)-1-Acryloyl-N-[4-(3-chloro-2,4-difluorophenylam...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of MAPK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Hanmi Research Center

Curated by ChEMBL
LigandPNGBDBM50300026((S)-1-Acryloyl-N-[4-(3-chloro-2-fluorophenylamino)...)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of Raf1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Hanmi Research Center

Curated by ChEMBL
LigandPNGBDBM50300027((S)-1-Acryloyl-N-[4-(3-chloro-2,4-difluorophenylam...)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of Flt1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Hanmi Research Center

Curated by ChEMBL
LigandPNGBDBM50300027((S)-1-Acryloyl-N-[4-(3-chloro-2,4-difluorophenylam...)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of Raf1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Hanmi Research Center

Curated by ChEMBL
LigandPNGBDBM50300026((S)-1-Acryloyl-N-[4-(3-chloro-2-fluorophenylamino)...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of Flt1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Hanmi Research Center

Curated by ChEMBL
LigandPNGBDBM50300026((S)-1-Acryloyl-N-[4-(3-chloro-2-fluorophenylamino)...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of Flt3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
Hanmi Research Center

Curated by ChEMBL
LigandPNGBDBM50300026((S)-1-Acryloyl-N-[4-(3-chloro-2-fluorophenylamino)...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of PDGFRalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Hanmi Research Center

Curated by ChEMBL
LigandPNGBDBM50300026((S)-1-Acryloyl-N-[4-(3-chloro-2-fluorophenylamino)...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of PDGFRbetaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Hanmi Research Center

Curated by ChEMBL
LigandPNGBDBM50300026((S)-1-Acryloyl-N-[4-(3-chloro-2-fluorophenylamino)...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of IGF1RMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Hanmi Research Center

Curated by ChEMBL
LigandPNGBDBM50300026((S)-1-Acryloyl-N-[4-(3-chloro-2-fluorophenylamino)...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of KitMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Hanmi Research Center

Curated by ChEMBL
LigandPNGBDBM50300026((S)-1-Acryloyl-N-[4-(3-chloro-2-fluorophenylamino)...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of FGFR1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Hanmi Research Center

Curated by ChEMBL
LigandPNGBDBM50300026((S)-1-Acryloyl-N-[4-(3-chloro-2-fluorophenylamino)...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of MetMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Hanmi Research Center

Curated by ChEMBL
LigandPNGBDBM50300026((S)-1-Acryloyl-N-[4-(3-chloro-2-fluorophenylamino)...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of Akt1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
Hanmi Research Center

Curated by ChEMBL
LigandPNGBDBM50300026((S)-1-Acryloyl-N-[4-(3-chloro-2-fluorophenylamino)...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CDK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 1(Homo sapiens (Human))
Hanmi Research Center

Curated by ChEMBL
LigandPNGBDBM50300026((S)-1-Acryloyl-N-[4-(3-chloro-2-fluorophenylamino)...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of MAPK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Hanmi Research Center

Curated by ChEMBL
LigandPNGBDBM50300027((S)-1-Acryloyl-N-[4-(3-chloro-2,4-difluorophenylam...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of Flt3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
Hanmi Research Center

Curated by ChEMBL
LigandPNGBDBM50300027((S)-1-Acryloyl-N-[4-(3-chloro-2,4-difluorophenylam...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of PDGFRalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Hanmi Research Center

Curated by ChEMBL
LigandPNGBDBM50300027((S)-1-Acryloyl-N-[4-(3-chloro-2,4-difluorophenylam...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of PDGFRbetaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Hanmi Research Center

Curated by ChEMBL
LigandPNGBDBM50300027((S)-1-Acryloyl-N-[4-(3-chloro-2,4-difluorophenylam...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of IGF1RMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Hanmi Research Center

Curated by ChEMBL
LigandPNGBDBM50300027((S)-1-Acryloyl-N-[4-(3-chloro-2,4-difluorophenylam...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of KitMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Hanmi Research Center

Curated by ChEMBL
LigandPNGBDBM50300027((S)-1-Acryloyl-N-[4-(3-chloro-2,4-difluorophenylam...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of FGFR1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Hanmi Research Center

Curated by ChEMBL
LigandPNGBDBM50300027((S)-1-Acryloyl-N-[4-(3-chloro-2,4-difluorophenylam...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of MetMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Hanmi Research Center

Curated by ChEMBL
LigandPNGBDBM50300027((S)-1-Acryloyl-N-[4-(3-chloro-2,4-difluorophenylam...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of Akt1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Displayed 1 to 50 (of 52 total ) | Next | Last >>
Jump to: