Compile Data Set for Download or QSAR
Report error Found 5 Enz. Inhib. hit(s) with all data for entry = 50035903
TargetDihydrofolate reductase(Human)
Institute

Curated by ChEMBL
LigandPNGBDBM18050(MTX | cid_126941 | Methotrexate | 2-[(4-{[(2,4-dia...)
Affinity DataIC50: 25nMAssay Description:Ability to inhibit purified Dihydrofolate reductase from human leukemic lymphoblasts was determined spectrophotometrically at 340 nM.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetDihydrofolate reductase(Human)
Institute

Curated by ChEMBL
LigandPNGBDBM50367055(4-Aminofolic acid | 4-Aminopteroic acid | Aminopte...)
Affinity DataIC50: 25nMAssay Description:Ability to inhibit purified Dihydrofolate reductase from human leukemic lymphoblasts was determined spectrophotometrically at 340 nM.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetDihydrofolate reductase(Human)
Institute

Curated by ChEMBL
LigandPNGBDBM50010924(CHEMBL65616 | 2-{4-[(2,4-Diamino-pteridin-6-ylmeth...)
Affinity DataIC50: 44nMAssay Description:Ability to inhibit purified Dihydrofolate reductase from human leukemic lymphoblasts was determined spectrophotometrically at 340 nM.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetDihydrofolate reductase(Human)
Institute

Curated by ChEMBL
LigandPNGBDBM50010927(CHEMBL65620 | 2-Cyano-4-{4-[(2,4-diamino-pteridin-...)
Affinity DataIC50: 57nMAssay Description:Ability to inhibit purified Dihydrofolate reductase from human leukemic lymphoblasts was determined spectrophotometrically at 340 nM.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetDihydrofolate reductase(Human)
Institute

Curated by ChEMBL
LigandPNGBDBM50010925(CHEMBL65711 | 2-{4-[(2,4-Diamino-pteridin-6-ylmeth...)
Affinity DataIC50: 88nMAssay Description:Ability to inhibit purified Dihydrofolate reductase from human leukemic lymphoblasts was determined spectrophotometrically at 340 nM.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed