Compile Data Set for Download or QSAR
Report error Found 13 Enz. Inhib. hit(s) with all data for entry = 50000888
TargetDihydrofolate reductase(Human)
University of South Alabama

Curated by ChEMBL
LigandPNGBDBM18050(MTX | cid_126941 | Methotrexate | 2-[(4-{[(2,4-dia...)
Affinity DataIC50: 3.90nMAssay Description:Compound was tested for its inhibitory activity on Recombinant Human Dihydrofolate Reductase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Human)
University of South Alabama

Curated by ChEMBL
LigandPNGBDBM50010932(2-{4-[2-(2,4-Diamino-pteridin-6-yl)-ethyl]-benzoyl...)
Affinity DataIC50: 4.10nMAssay Description:Compound was tested for its inhibitory activity on Recombinant Human Dihydrofolate Reductase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Human)
University of South Alabama

Curated by ChEMBL
LigandPNGBDBM50016460(Edatrexate | GNF-Pf-63 | (S)-2-{4-[1-(2,4-Diamino-...)
Affinity DataIC50: 4.40nMAssay Description:Compound was tested for its inhibitory activity on Recombinant Human Dihydrofolate Reductase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Human)
University of South Alabama

Curated by ChEMBL
LigandPNGBDBM50010930(CHEMBL307820 | 2-{4-[(2,4-Diamino-pteridin-6-ylmet...)
Affinity DataIC50: 5.30nMAssay Description:Compound was tested for its inhibitory activity on Recombinant Human Dihydrofolate Reductase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Human)
University of South Alabama

Curated by ChEMBL
LigandPNGBDBM50010928(CHEMBL308279 | 2-{4-[1-(2,4-Diamino-pteridin-6-ylm...)
Affinity DataIC50: 5.80nMAssay Description:Compound was tested for its inhibitory activity on Recombinant Human Dihydrofolate Reductase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Human)
University of South Alabama

Curated by ChEMBL
LigandPNGBDBM50010931(CHEMBL73267 | 2-{4-[2-(2,4-Diamino-pteridin-6-yl)-...)
Affinity DataIC50: 5.90nMAssay Description:Compound was tested for its inhibitory activity on Recombinant Human Dihydrofolate Reductase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Human)
University of South Alabama

Curated by ChEMBL
LigandPNGBDBM50010924(CHEMBL65616 | 2-{4-[(2,4-Diamino-pteridin-6-ylmeth...)
Affinity DataIC50: 6.40nMAssay Description:Compound was tested for its inhibitory activity on Recombinant Human Dihydrofolate Reductase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Human)
University of South Alabama

Curated by ChEMBL
LigandPNGBDBM50010929(CHEMBL307486 | 2-{4-[2-(2,4-Diamino-pteridin-6-yl)...)
Affinity DataIC50: 8.80nMAssay Description:Compound was tested for its inhibitory activity on Recombinant Human Dihydrofolate Reductase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetFolylpolyglutamate synthase, mitochondrial(Human)
University of South Alabama

Curated by ChEMBL
LigandPNGBDBM50010931(CHEMBL73267 | 2-{4-[2-(2,4-Diamino-pteridin-6-yl)-...)
Affinity DataIC50: 5.00E+4nMAssay Description:Compound was evaluated for the inhibition of Folyl-polyglutamate synthase in CCRF-CEM Human leukemia cell.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetFolylpolyglutamate synthase, mitochondrial(Human)
University of South Alabama

Curated by ChEMBL
LigandPNGBDBM50010928(CHEMBL308279 | 2-{4-[1-(2,4-Diamino-pteridin-6-ylm...)
Affinity DataIC50: 1.18E+5nMAssay Description:Compound was evaluated for the inhibition of Folyl-polyglutamate synthase in CCRF-CEM Human leukemia cell.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetFolylpolyglutamate synthase, mitochondrial(Human)
University of South Alabama

Curated by ChEMBL
LigandPNGBDBM50010929(CHEMBL307486 | 2-{4-[2-(2,4-Diamino-pteridin-6-yl)...)
Affinity DataIC50: 2.00E+5nMAssay Description:Compound was evaluated for the inhibition of Folyl-polyglutamate synthase in CCRF-CEM Human leukemia cell.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetFolylpolyglutamate synthase, mitochondrial(Human)
University of South Alabama

Curated by ChEMBL
LigandPNGBDBM50010930(CHEMBL307820 | 2-{4-[(2,4-Diamino-pteridin-6-ylmet...)
Affinity DataIC50: 2.00E+5nMAssay Description:Compound was evaluated for the inhibition of Folyl-polyglutamate synthase in CCRF-CEM Human leukemia cell.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetFolylpolyglutamate synthase, mitochondrial(Human)
University of South Alabama

Curated by ChEMBL
LigandPNGBDBM50010924(CHEMBL65616 | 2-{4-[(2,4-Diamino-pteridin-6-ylmeth...)
Affinity DataIC50: 2.00E+5nMAssay Description:Compound was evaluated for the inhibition of Folyl-polyglutamate synthase in CCRF-CEM Human leukemia cell.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed