Compile Data Set for Download or QSAR
Report error Found 57 Enz. Inhib. hit(s) with all data for entry = 50031020
TargetRenin(Human)
Vitae Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50305450(methyl (S)-4-(3-chlorophenyl)-4-((R)-1-((S)-1-cycl...)
Affinity DataIC50: 0.180nMAssay Description:Inhibition of trypsin-activated human recombinant reninMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetRenin(Human)
Vitae Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50305465(methyl 2-((R)-((R)-1-((S)-1-cyclohexyl-3-(methylam...)
Affinity DataIC50: 0.230nMAssay Description:Inhibition of trypsin-activated human recombinant reninMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetRenin(Human)
Vitae Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM29949(piperidine-1-carboxamide, 21l)
Affinity DataIC50: 0.470nMAssay Description:Inhibition of trypsin-activated human recombinant reninMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetRenin(Human)
Vitae Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50305454(methyl 2-((R)-((R)-1-((S)-1-cyclohexyl-3-(methylam...)
Affinity DataIC50: 0.470nMAssay Description:Inhibition of trypsin-activated human recombinant reninMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetRenin(Human)
Vitae Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50305452(methyl 2-((R)-(3-chlorophenyl)((R)-1-((S)-1-cycloh...)
Affinity DataIC50: 0.480nMAssay Description:Inhibition of trypsin-activated human recombinant reninMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetRenin(Human)
Vitae Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50305456(methyl 2-((R)-((R)-1-((S)-1-amino-3-cyclohexylprop...)
Affinity DataIC50: 0.480nMAssay Description:Inhibition of trypsin-activated human recombinant reninMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetRenin(Human)
Vitae Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50305466(methyl 2-((R)-(3-chloro-5-fluorophenyl)((R)-1-((S)...)
Affinity DataIC50: 0.520nMAssay Description:Inhibition of trypsin-activated human recombinant reninMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetRenin(Human)
Vitae Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM17950(CHEMBL1639 | Rasilez | (2S,4S,5S,7S)-5-amino-N-(2-...)
Affinity DataIC50: 0.530nMAssay Description:Inhibition of trypsin-activated human recombinant reninMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetRenin(Human)
Vitae Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50305457(methyl 2-((R)-((R)-1-((S)-1-amino-3-cyclohexylprop...)
Affinity DataIC50: 0.580nMAssay Description:Inhibition of trypsin-activated human recombinant reninMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetRenin(Human)
Vitae Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50305453(methyl 2-((R)-((R)-1-((S)-1-cyclohexyl-3-(methylam...)
Affinity DataIC50: 0.590nMAssay Description:Inhibition of trypsin-activated human recombinant reninMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetRenin(Human)
Vitae Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50305462(methyl 2-((R)-(3-chloro-2-fluorophenyl)((R)-1-((S)...)
Affinity DataIC50: 0.610nMAssay Description:Inhibition of trypsin-activated human recombinant reninMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetRenin(Human)
Vitae Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50305461(methyl 2-((R)-((R)-1-((S)-1-cyclohexyl-3-(methylam...)
Affinity DataIC50: 0.620nMAssay Description:Inhibition of trypsin-activated human recombinant reninMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetRenin(Human)
Vitae Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50305463(methyl 2-((R)-(5-chloro-2-fluorophenyl)((R)-1-((S)...)
Affinity DataIC50: 0.620nMAssay Description:Inhibition of trypsin-activated human recombinant reninMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetRenin(Human)
Vitae Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM17950(CHEMBL1639 | Rasilez | (2S,4S,5S,7S)-5-amino-N-(2-...)
Affinity DataIC50: 0.650nMAssay Description:Inhibition of human recombinant renin assessed as decrease in plasma renin activity by competitive radioimmunoassay in presence of human plasmaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetRenin(Human)
Vitae Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50305452(methyl 2-((R)-(3-chlorophenyl)((R)-1-((S)-1-cycloh...)
Affinity DataIC50: 0.820nMAssay Description:Inhibition of human recombinant renin assessed as decrease in plasma renin activity by competitive radioimmunoassay in presence of human plasmaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetRenin(Human)
Vitae Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50305458(methyl 2-((R)-(3-chlorophenyl)((R)-1-((S)-1-cycloh...)
Affinity DataIC50: 0.870nMAssay Description:Inhibition of trypsin-activated human recombinant reninMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetRenin(Human)
Vitae Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50305455(methyl 2-((R)-((R)-1-((S)-1-cyclohexyl-3-(methylam...)
Affinity DataIC50: 1.17nMAssay Description:Inhibition of trypsin-activated human recombinant reninMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetRenin(Human)
Vitae Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50305465(methyl 2-((R)-((R)-1-((S)-1-cyclohexyl-3-(methylam...)
Affinity DataIC50: 1.20nMAssay Description:Inhibition of human recombinant renin assessed as decrease in plasma renin activity by competitive radioimmunoassay in presence of human plasmaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetRenin(Human)
Vitae Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50305441((3R)-3-[(1S)-4-(acetylamino)-1-(3-chlorophenyl)-1-...)
Affinity DataIC50: 1.30nMAssay Description:Inhibition of trypsin-activated human recombinant reninMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetRenin(Human)
Vitae Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50305442((R)-3-((S)-1-(3-chlorophenyl)-1-hydroxy-4-propiona...)
Affinity DataIC50: 1.5nMAssay Description:Inhibition of trypsin-activated human recombinant reninMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetRenin(Human)
Vitae Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50305466(methyl 2-((R)-(3-chloro-5-fluorophenyl)((R)-1-((S)...)
Affinity DataIC50: 1.5nMAssay Description:Inhibition of human recombinant renin assessed as decrease in plasma renin activity by competitive radioimmunoassay in presence of human plasmaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetRenin(Human)
Vitae Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50305460(methyl 2-((R)-((R)-1-((S)-1-cyclohexyl-3-(methylam...)
Affinity DataIC50: 1.70nMAssay Description:Inhibition of trypsin-activated human recombinant reninMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetRenin(Human)
Vitae Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50305453(methyl 2-((R)-((R)-1-((S)-1-cyclohexyl-3-(methylam...)
Affinity DataIC50: 1.80nMAssay Description:Inhibition of human recombinant renin assessed as decrease in plasma renin activity by competitive radioimmunoassay in presence of human plasmaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetRenin(Human)
Vitae Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50305459(methyl 2-((R)-((R)-1-((S)-1-cyclohexyl-3-(ethylami...)
Affinity DataIC50: 2.10nMAssay Description:Inhibition of trypsin-activated human recombinant reninMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetRenin(Human)
Vitae Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50305463(methyl 2-((R)-(5-chloro-2-fluorophenyl)((R)-1-((S)...)
Affinity DataIC50: 2.10nMAssay Description:Inhibition of human recombinant renin assessed as decrease in plasma renin activity by competitive radioimmunoassay in presence of human plasmaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetRenin(Human)
Vitae Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50305464(methyl 2-((R)-((R)-1-((S)-1-cyclohexyl-3-(methylam...)
Affinity DataIC50: 2.5nMAssay Description:Inhibition of trypsin-activated human recombinant reninMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetRenin(Human)
Vitae Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50305456(methyl 2-((R)-((R)-1-((S)-1-amino-3-cyclohexylprop...)
Affinity DataIC50: 2.60nMAssay Description:Inhibition of human recombinant renin assessed as decrease in plasma renin activity by competitive radioimmunoassay in presence of human plasmaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetRenin(Human)
Vitae Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50305461(methyl 2-((R)-((R)-1-((S)-1-cyclohexyl-3-(methylam...)
Affinity DataIC50: 2.70nMAssay Description:Inhibition of human recombinant renin assessed as decrease in plasma renin activity by competitive radioimmunoassay in presence of human plasmaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetRenin(Human)
Vitae Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50305455(methyl 2-((R)-((R)-1-((S)-1-cyclohexyl-3-(methylam...)
Affinity DataIC50: 2.90nMAssay Description:Inhibition of human recombinant renin assessed as decrease in plasma renin activity by competitive radioimmunoassay in presence of human plasmaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetRenin(Human)
Vitae Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50305457(methyl 2-((R)-((R)-1-((S)-1-amino-3-cyclohexylprop...)
Affinity DataIC50: 3.30nMAssay Description:Inhibition of human recombinant renin assessed as decrease in plasma renin activity by competitive radioimmunoassay in presence of human plasmaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetRenin(Human)
Vitae Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50305462(methyl 2-((R)-(3-chloro-2-fluorophenyl)((R)-1-((S)...)
Affinity DataIC50: 3.40nMAssay Description:Inhibition of human recombinant renin assessed as decrease in plasma renin activity by competitive radioimmunoassay in presence of human plasmaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetRenin(Human)
Vitae Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50305450(methyl (S)-4-(3-chlorophenyl)-4-((R)-1-((S)-1-cycl...)
Affinity DataIC50: 3.70nMAssay Description:Inhibition of human recombinant renin assessed as decrease in plasma renin activity by competitive radioimmunoassay in presence of human plasmaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetRenin(Human)
Vitae Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50305454(methyl 2-((R)-((R)-1-((S)-1-cyclohexyl-3-(methylam...)
Affinity DataIC50: 4nMAssay Description:Inhibition of human recombinant renin assessed as decrease in plasma renin activity by competitive radioimmunoassay in presence of human plasmaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetRenin(Human)
Vitae Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50305460(methyl 2-((R)-((R)-1-((S)-1-cyclohexyl-3-(methylam...)
Affinity DataIC50: 6.20nMAssay Description:Inhibition of human recombinant renin assessed as decrease in plasma renin activity by competitive radioimmunoassay in presence of human plasmaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetRenin(Human)
Vitae Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50305458(methyl 2-((R)-(3-chlorophenyl)((R)-1-((S)-1-cycloh...)
Affinity DataIC50: 7.70nMAssay Description:Inhibition of human recombinant renin assessed as decrease in plasma renin activity by competitive radioimmunoassay in presence of human plasmaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetRenin(Human)
Vitae Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM29949(piperidine-1-carboxamide, 21l)
Affinity DataIC50: 13nMAssay Description:Inhibition of human recombinant renin assessed as decrease in plasma renin activity by competitive radioimmunoassay in presence of human plasmaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetRenin(Human)
Vitae Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50305451(ethyl (S)-4-(3-chlorophenyl)-4-((R)-1-((S)-1-cyclo...)
Affinity DataIC50: 14nMAssay Description:Inhibition of trypsin-activated human recombinant reninMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetRenin(Human)
Vitae Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50305441((3R)-3-[(1S)-4-(acetylamino)-1-(3-chlorophenyl)-1-...)
Affinity DataIC50: 16nMAssay Description:Inhibition of human recombinant renin assessed as decrease in plasma renin activity by competitive radioimmunoassay in presence of human plasmaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetRenin(Human)
Vitae Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50305464(methyl 2-((R)-((R)-1-((S)-1-cyclohexyl-3-(methylam...)
Affinity DataIC50: 16.6nMAssay Description:Inhibition of human recombinant renin assessed as decrease in plasma renin activity by competitive radioimmunoassay in presence of human plasmaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetRenin(Human)
Vitae Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50305444((R)-3-((S)-1-(3-chlorophenyl)-4-(cyclopropanecarbo...)
Affinity DataIC50: 17nMAssay Description:Inhibition of trypsin-activated human recombinant reninMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetRenin(Human)
Vitae Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50305459(methyl 2-((R)-((R)-1-((S)-1-cyclohexyl-3-(ethylami...)
Affinity DataIC50: 18nMAssay Description:Inhibition of human recombinant renin assessed as decrease in plasma renin activity by competitive radioimmunoassay in presence of human plasmaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetRenin(Human)
Vitae Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM29940(piperidine-1-carboxamide, 21c)
Affinity DataIC50: 21nMAssay Description:Inhibition of trypsin-activated human recombinant reninMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetRenin(Human)
Vitae Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50305442((R)-3-((S)-1-(3-chlorophenyl)-1-hydroxy-4-propiona...)
Affinity DataIC50: 21nMAssay Description:Inhibition of human recombinant renin assessed as decrease in plasma renin activity by competitive radioimmunoassay in presence of human plasmaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetRenin(Human)
Vitae Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50305446((R)-3-((S)-1-(3-chlorophenyl)-1-hydroxy-4-ureidobu...)
Affinity DataIC50: 31nMAssay Description:Inhibition of trypsin-activated human recombinant reninMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetRenin(Human)
Vitae Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM29934(piperidine-1-carboxamide, 7h)
Affinity DataIC50: 40nMAssay Description:Inhibition of trypsin-activated human recombinant reninMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetRenin(Human)
Vitae Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50305449((R)-3-((S)-1-(3-chlorophenyl)-1-hydroxy-4-(sulfamo...)
Affinity DataIC50: 46nMAssay Description:Inhibition of trypsin-activated human recombinant reninMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetRenin(Human)
Vitae Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50305447((R)-3-((S)-1-(3-chlorophenyl)-1-hydroxy-4-(3-methy...)
Affinity DataIC50: 46nMAssay Description:Inhibition of trypsin-activated human recombinant reninMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetRenin(Human)
Vitae Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50305443((R)-3-((S)-4-butyramido-1-(3-chlorophenyl)-1-hydro...)
Affinity DataIC50: 57nMAssay Description:Inhibition of trypsin-activated human recombinant reninMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetRenin(Human)
Vitae Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50305444((R)-3-((S)-1-(3-chlorophenyl)-4-(cyclopropanecarbo...)
Affinity DataIC50: 79nMAssay Description:Inhibition of human recombinant renin assessed as decrease in plasma renin activity by competitive radioimmunoassay in presence of human plasmaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetRenin(Human)
Vitae Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50305447((R)-3-((S)-1-(3-chlorophenyl)-1-hydroxy-4-(3-methy...)
Affinity DataIC50: 141nMAssay Description:Inhibition of human recombinant renin assessed as decrease in plasma renin activity by competitive radioimmunoassay in presence of human plasmaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
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