Compile Data Set for Download or QSAR
Report error Found 14 Enz. Inhib. hit(s) with all data for entry = 50031382
TargetAldo-keto reductase family 1 member B1(Rat)
Institute of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM16314(N-{[6-methoxy-5-(trifluoromethyl)naphthalen-1-yl]c...)
Affinity DataIC50: 50nMAssay Description:Inhibition of Albino rat eye lens ALR2 assessed as NADPH oxidation by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAldo-keto reductase family 1 member B1(Rat)
Institute of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50312519([3,4-Dioxo-10-(4-phenoxycarbonylmethyl-benzyl)-3,4...)
Affinity DataIC50: 320nMAssay Description:Inhibition of Albino rat eye lens ALR2 assessed as NADPH oxidation by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Rat)
Institute of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50107141((10-Benzyl-3,4-dioxo-3,4-dihydro-10H-benzo[4,5]imi...)
Affinity DataIC50: 360nMAssay Description:Inhibition of Albino rat eye lens ALR2 assessed as NADPH oxidation by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Rat)
Institute of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM16312(CHEMBL266497 | (4S)-6-fluoro-2,3-dihydrospiro[1-be...)
Affinity DataIC50: 620nMAssay Description:Inhibition of Albino rat eye lens ALR2 assessed as NADPH oxidation by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Rat)
Institute of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50312515([3,4-Dioxo-10-(4-trichloromethyl-benzyl)-3,4-dihyd...)
Affinity DataIC50: 4.24E+3nMAssay Description:Inhibition of Albino rat eye lens ALR2 assessed as NADPH oxidation by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Rat)
Institute of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50312510([10-(4-Hydroxy-benzyl)-3,4-dioxo-3,4-dihydro-10H-b...)
Affinity DataIC50: 4.56E+3nMAssay Description:Inhibition of Albino rat eye lens ALR2 assessed as NADPH oxidation by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Rat)
Institute of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50312514([10-(4-Bromo-benzyl)-3,4-dioxo-3,4-dihydro-10H-ben...)
Affinity DataIC50: 4.76E+3nMAssay Description:Inhibition of Albino rat eye lens ALR2 assessed as NADPH oxidation by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Rat)
Institute of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50312518([10-(2,4-Difluoro-benzyl)-3,4-dioxo-3,4-dihydro-10...)
Affinity DataIC50: 8.22E+3nMAssay Description:Inhibition of Albino rat eye lens ALR2 assessed as NADPH oxidation by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Rat)
Institute of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50312511([10-(4-Bromo-2-chloro-benzyl)-3,4-dioxo-3,4-dihydr...)
Affinity DataIC50: 1.43E+4nMAssay Description:Inhibition of Albino rat eye lens ALR2 assessed as NADPH oxidation by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Rat)
Institute of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50312517([10-(3,5-Dinitro-benzyl)-3,4-dioxo-3,4-dihydro-10H...)
Affinity DataIC50: 2.28E+4nMAssay Description:Inhibition of Albino rat eye lens ALR2 assessed as NADPH oxidation by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Rat)
Institute of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50312512([10-(4-Amino-benzyl)-3,4-dioxo-3,4-dihydro-10H-ben...)
Affinity DataIC50: 3.24E+4nMAssay Description:Inhibition of Albino rat eye lens ALR2 assessed as NADPH oxidation by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Rat)
Institute of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50312516([10-(4-Chloro-2-fluoro-benzyl)-3,4-dioxo-3,4-dihyd...)
Affinity DataIC50: 3.65E+4nMAssay Description:Inhibition of Albino rat eye lens ALR2 assessed as NADPH oxidation by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Rat)
Institute of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50312513([10-(4-Dimethylamino-benzyl)-3,4-dioxo-3,4-dihydro...)
Affinity DataIC50: 3.84E+4nMAssay Description:Inhibition of Albino rat eye lens ALR2 assessed as NADPH oxidation by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Rat)
Institute of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50312509((10-Ethyl-3,4-dioxo-3,4-dihydro-10H-benzo[4,5]imid...)
Affinity DataIC50: 4.24E+4nMAssay Description:Inhibition of Albino rat eye lens ALR2 assessed as NADPH oxidation by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed