Compile Data Set for Download or QSAR
Report error Found 49 Enz. Inhib. hit(s) with all data for entry = 50031053
TargetRAC-alpha serine/threonine-protein kinase(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50306095BDBM50306095((S)-1-(6-fluoro-1H-indol-3-yl)-3-(6-(furan-3-yl)-5...)
Affinity DataIC50: 0.800nMAssay Description:Inhibition of full length AKT1More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50306097BDBM50306097((2S)-1-(1H-indol-3-yl)-3-(5-(3-methyl-1H-indazol-5...)
Affinity DataIC50: 0.800nMAssay Description:Inhibition of full length AKT1More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50306094BDBM50306094((S)-1-(7-fluoro-1H-indol-3-yl)-3-(6-(furan-3-yl)-5...)
Affinity DataIC50: 1nMAssay Description:Inhibition of full length AKT1More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50305878BDBM50305878((S)-1-(6-(furan-3-yl)-5-(3-methyl-1H-indazol-5-yl)...)
Affinity DataIC50: 1nMAssay Description:Inhibition of full length AKT1More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50306096BDBM50306096((S)-1-(5-fluoro-1H-indol-3-yl)-3-(6-(furan-3-yl)-5...)
Affinity DataIC50: 1nMAssay Description:Inhibition of full length AKT1More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50306084BDBM50306084(2-(5-((S)-2-amino-3-phenylpropoxy)-3-(3-methyl-1H-...)
Affinity DataIC50: 3nMAssay Description:Inhibition of full length AKT1More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50306093BDBM50306093((S)-1-(6-(furan-3-yl)-5-(3-methyl-1H-indazol-5-yl)...)
Affinity DataIC50: 8nMAssay Description:Inhibition of full length AKT1More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50306092BDBM50306092((S)-1-(6-(furan-3-yl)-5-(3-methyl-1H-indazol-5-yl)...)
Affinity DataIC50: 10nMAssay Description:Inhibition of full length AKT1More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50306105BDBM50306105(2-(5-((S)-2-amino-3-phenylpropoxy)-3-(3-methyl-1H-...)
Affinity DataIC50: 10nMAssay Description:Inhibition of truncated AKT1More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50306103BDBM50306103((S)-1-(6-(furan-3-yl)-5-(3-methyl-1H-indazol-5-yl)...)
Affinity DataIC50: 10nMAssay Description:Inhibition of full length AKT1More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50306091BDBM50306091((S)-1-(6-(furan-3-yl)-5-(3-methyl-1H-indazol-5-yl)...)
Affinity DataIC50: 13nMAssay Description:Inhibition of full length AKT1More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50306089BDBM50306089(2-(5-((S)-2-amino-3-phenylpropoxy)-3-(3-methyl-1H-...)
Affinity DataIC50: 15nMAssay Description:Inhibition of full length AKT1More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50306100BDBM50306100((S)-1-(5-(3-methyl-1H-indazol-5-yl)-6-(1H-pyrrol-2...)
Affinity DataIC50: 15nMAssay Description:Inhibition of full length AKT1More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50306090BDBM50306090((S)-1-(5-(3-methyl-1H-indazol-5-yl)-6-phenylpyridi...)
Affinity DataIC50: 50nMAssay Description:Inhibition of full length AKT1More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50306101BDBM50306101((S)-1-(5-(3-methyl-1H-indazol-5-yl)-6-(thiophen-3-...)
Affinity DataIC50: 50nMAssay Description:Inhibition of full length AKT1More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50306085BDBM50306085(2-(5-((S)-2-amino-3-phenylpropoxy)-3-(3-methyl-1H-...)
Affinity DataIC50: 63nMAssay Description:Inhibition of full length AKT1More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50306088BDBM50306088((S)-3-(5-(2-amino-3-phenylpropoxy)-3-(3-methyl-1H-...)
Affinity DataIC50: 79nMAssay Description:Inhibition of full length AKT1More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetRho-associated protein kinase 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 15138BDBM15138(Biochemistry 469551 Compound 11 | 5-indazolyl pyri...)
Affinity DataIC50: 79nMAssay Description:Inhibition of ROCK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50306102BDBM50306102((S)-1-(5-(3-methyl-1H-indazol-5-yl)-6-(thiophen-2-...)
Affinity DataIC50: 79nMAssay Description:Inhibition of full length AKT1More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50306097BDBM50306097((2S)-1-(1H-indol-3-yl)-3-(5-(3-methyl-1H-indazol-5...)
Affinity DataIC50: 84nMAssay Description:Inhibition of AKT1 in human BT474 cells assessed as phosphorylation of GSK3More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50306086BDBM50306086((2S)-1-(6-(2-methoxyphenyl)-5-(3-methyl-1H-indazol...)
Affinity DataIC50: 100nMAssay Description:Inhibition of full length AKT1More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 15138BDBM15138(Biochemistry 469551 Compound 11 | 5-indazolyl pyri...)
Affinity DataIC50: 125nMAssay Description:Inhibition of full length AKT1More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50306095BDBM50306095((S)-1-(6-fluoro-1H-indol-3-yl)-3-(6-(furan-3-yl)-5...)
Affinity DataIC50: 220nMAssay Description:Inhibition of AKT1 in human BT474 cells assessed as phosphorylation of GSK3More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50306094BDBM50306094((S)-1-(7-fluoro-1H-indol-3-yl)-3-(6-(furan-3-yl)-5...)
Affinity DataIC50: 260nMAssay Description:Inhibition of AKT1 in human BT474 cells assessed as phosphorylation of GSK3More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50306096BDBM50306096((S)-1-(5-fluoro-1H-indol-3-yl)-3-(6-(furan-3-yl)-5...)
Affinity DataIC50: 360nMAssay Description:Inhibition of AKT1 in human BT474 cells assessed as phosphorylation of GSK3More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50306087BDBM50306087((S)-4-(5-(2-amino-3-phenylpropoxy)-3-(3-methyl-1H-...)
Affinity DataIC50: 500nMAssay Description:Inhibition of full length AKT1More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50305878BDBM50305878((S)-1-(6-(furan-3-yl)-5-(3-methyl-1H-indazol-5-yl)...)
Affinity DataIC50: 500nMAssay Description:Inhibition of AKT1 in human BT474 cells assessed as phosphorylation of GSK3More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50306098BDBM50306098((S)-4-(5-(2-amino-3-phenylpropoxy)-3-(3-methyl-1H-...)
Affinity DataIC50: 720nMAssay Description:Inhibition of full length AKT1More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50306104BDBM50306104((S)-1-(6-(furan-2-yl)-5-(3-methyl-1H-indazol-5-yl)...)
Affinity DataIC50: 790nMAssay Description:Inhibition of truncated AKT1More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50306093BDBM50306093((S)-1-(6-(furan-3-yl)-5-(3-methyl-1H-indazol-5-yl)...)
Affinity DataIC50: 930nMAssay Description:Inhibition of AKT1 in human BT474 cells assessed as phosphorylation of GSK3More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetRho-associated protein kinase 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50306104BDBM50306104((S)-1-(6-(furan-2-yl)-5-(3-methyl-1H-indazol-5-yl)...)
Affinity DataIC50: 1.29E+3nMAssay Description:Inhibition of ROCK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetRho-associated protein kinase 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50306087BDBM50306087((S)-4-(5-(2-amino-3-phenylpropoxy)-3-(3-methyl-1H-...)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of ROCK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetRho-associated protein kinase 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50305878BDBM50305878((S)-1-(6-(furan-3-yl)-5-(3-methyl-1H-indazol-5-yl)...)
Affinity DataIC50: 1.58E+3nMAssay Description:Inhibition of ROCK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetRho-associated protein kinase 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50306102BDBM50306102((S)-1-(5-(3-methyl-1H-indazol-5-yl)-6-(thiophen-2-...)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of ROCK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50306092BDBM50306092((S)-1-(6-(furan-3-yl)-5-(3-methyl-1H-indazol-5-yl)...)
Affinity DataIC50: 4.30E+3nMAssay Description:Inhibition of AKT1 in human BT474 cells assessed as phosphorylation of GSK3More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetRho-associated protein kinase 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50306103BDBM50306103((S)-1-(6-(furan-3-yl)-5-(3-methyl-1H-indazol-5-yl)...)
Affinity DataIC50: 5.20E+3nMAssay Description:Inhibition of ROCK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetRho-associated protein kinase 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50306101BDBM50306101((S)-1-(5-(3-methyl-1H-indazol-5-yl)-6-(thiophen-3-...)
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of ROCK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50306091BDBM50306091((S)-1-(6-(furan-3-yl)-5-(3-methyl-1H-indazol-5-yl)...)
Affinity DataIC50: 6.80E+3nMAssay Description:Inhibition of AKT1 in human BT474 cells assessed as phosphorylation of GSK3More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetRho-associated protein kinase 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50306084BDBM50306084(2-(5-((S)-2-amino-3-phenylpropoxy)-3-(3-methyl-1H-...)
Affinity DataIC50: 7.60E+3nMAssay Description:Inhibition of ROCK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetRho-associated protein kinase 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50306089BDBM50306089(2-(5-((S)-2-amino-3-phenylpropoxy)-3-(3-methyl-1H-...)
Affinity DataIC50: 9.50E+3nMAssay Description:Inhibition of ROCK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetRho-associated protein kinase 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50306105BDBM50306105(2-(5-((S)-2-amino-3-phenylpropoxy)-3-(3-methyl-1H-...)
Affinity DataIC50: 9.80E+3nMAssay Description:Inhibition of ROCK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetRho-associated protein kinase 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50306100BDBM50306100((S)-1-(5-(3-methyl-1H-indazol-5-yl)-6-(1H-pyrrol-2...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of ROCK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetRho-associated protein kinase 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50306099BDBM50306099((S)-4-(5-(2-amino-3-phenylpropoxy)-3-(3-methyl-1H-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of ROCK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetRho-associated protein kinase 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50306098BDBM50306098((S)-4-(5-(2-amino-3-phenylpropoxy)-3-(3-methyl-1H-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of ROCK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetRho-associated protein kinase 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50306086BDBM50306086((2S)-1-(6-(2-methoxyphenyl)-5-(3-methyl-1H-indazol...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of ROCK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetRho-associated protein kinase 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50306085BDBM50306085(2-(5-((S)-2-amino-3-phenylpropoxy)-3-(3-methyl-1H-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of ROCK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetRho-associated protein kinase 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50306090BDBM50306090((S)-1-(5-(3-methyl-1H-indazol-5-yl)-6-phenylpyridi...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of ROCK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetRho-associated protein kinase 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50306088BDBM50306088((S)-3-(5-(2-amino-3-phenylpropoxy)-3-(3-methyl-1H-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of ROCK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50306099BDBM50306099((S)-4-(5-(2-amino-3-phenylpropoxy)-3-(3-methyl-1H-...)
Affinity DataIC50: 1.05E+4nMAssay Description:Inhibition of truncated AKT1More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed