Compile Data Set for Download or QSAR
Report error Found 45 Enz. Inhib. hit(s) with all data for entry = 50031057
TargetPoly [ADP-ribose] polymerase 1(Human)
Irbm-Merck Research Laboratories Rome

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50306179BDBM50306179(5-fluoro-2-(4-((methylamino)methyl)phenyl)-2H-inda...)
Affinity DataIC50: 1.40nMAssay Description:Inhibition of human PARP1 after 3 hrs using [3H]NAD+ by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Irbm-Merck Research Laboratories Rome

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50306173BDBM50306173(5-fluoro-2-(3-fluoro-4-((methylamino)methyl)phenyl...)
Affinity DataIC50: 2nMAssay Description:Inhibition of human PARP1 after 3 hrs using [3H]NAD+ by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Irbm-Merck Research Laboratories Rome

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50306186BDBM50306186(2-(3-methoxy-4-((methylamino)methyl)phenyl)-2H-ind...)
Affinity DataIC50: 4nMAssay Description:Inhibition of human PARP1 after 3 hrs using [3H]NAD+ by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Irbm-Merck Research Laboratories Rome

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50306168BDBM50306168(2-(4-(azetidine-3-carboxamido)-3-fluorophenyl)-5-f...)
Affinity DataIC50: 4nMAssay Description:Inhibition of human PARP1 after 3 hrs using [3H]NAD+ by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Irbm-Merck Research Laboratories Rome

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50306184BDBM50306184(2-(3-fluoro-4-((methylamino)methyl)phenyl)-2H-inda...)
Affinity DataIC50: 4nMAssay Description:Inhibition of human PARP1 after 3 hrs using [3H]NAD+ by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Irbm-Merck Research Laboratories Rome

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50306210BDBM50306210(2-(4-((methylamino)methyl)phenyl)-2H-indazole-7-ca...)
Affinity DataIC50: 5nMAssay Description:Inhibition of human PARP1 after 3 hrs using [3H]NAD+ by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Irbm-Merck Research Laboratories Rome

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50306181BDBM50306181(5-chloro-2-(4-((methylamino)methyl)phenyl)-2H-inda...)
Affinity DataIC50: 5nMAssay Description:Inhibition of human PARP1 after 3 hrs using [3H]NAD+ by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Irbm-Merck Research Laboratories Rome

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50306171BDBM50306171(2-(4-(azetidine-3-carboxamido)phenyl)-5-fluoro-2H-...)
Affinity DataIC50: 5nMAssay Description:Inhibition of human PARP1 after 3 hrs using [3H]NAD+ by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Irbm-Merck Research Laboratories Rome

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50306187BDBM50306187(2-(4-((methylamino)methyl)-3-(trifluoromethyl)phen...)
Affinity DataIC50: 5nMAssay Description:Inhibition of human PARP1 after 3 hrs using [3H]NAD+ by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Irbm-Merck Research Laboratories Rome

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50306170BDBM50306170(5-fluoro-2-(4-(1-methylazetidine-3-carboxamido)phe...)
Affinity DataIC50: 6nMAssay Description:Inhibition of human PARP1 after 3 hrs using [3H]NAD+ by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Irbm-Merck Research Laboratories Rome

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50306167BDBM50306167(5-fluoro-2-(3-fluoro-4-(1-methylazetidine-3-carbox...)
Affinity DataIC50: 6nMAssay Description:Inhibition of human PARP1 after 3 hrs using [3H]NAD+ by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Irbm-Merck Research Laboratories Rome

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50306174BDBM50306174(5-fluoro-2-(2-fluoro-4-((methylamino)methyl)phenyl...)
Affinity DataIC50: 6nMAssay Description:Inhibition of human PARP1 after 3 hrs using [3H]NAD+ by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Irbm-Merck Research Laboratories Rome

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50306180BDBM50306180(4-fluoro-2-(4-((methylamino)methyl)phenyl)-2H-inda...)
Affinity DataIC50: 8nMAssay Description:Inhibition of human PARP1 after 3 hrs using [3H]NAD+ by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Irbm-Merck Research Laboratories Rome

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50306209BDBM50306209(2-(4-(2-(dimethylamino)ethylcarbamoyl)phenyl)-2H-i...)
Affinity DataIC50: 10nMAssay Description:Inhibition of human PARP1 after 3 hrs using [3H]NAD+ by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Irbm-Merck Research Laboratories Rome

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50306192BDBM50306192(2-(4-(azetidine-3-carboxamido)phenyl)-2H-indazole-...)
Affinity DataIC50: 10nMAssay Description:Inhibition of human PARP1 after 3 hrs using [3H]NAD+ by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Irbm-Merck Research Laboratories Rome

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50306196BDBM50306196(2-(4-(1-methylpiperidine-4-carboxamido)phenyl)-2H-...)
Affinity DataIC50: 10nMAssay Description:Inhibition of human PARP1 after 3 hrs using [3H]NAD+ by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Irbm-Merck Research Laboratories Rome

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50306200BDBM50306200(2-(4-(2-(pyrrolidin-1-yl)acetamido)phenyl)-2H-inda...)
Affinity DataIC50: 10nMAssay Description:Inhibition of human PARP1 after 3 hrs using [3H]NAD+ by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Irbm-Merck Research Laboratories Rome

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50306205BDBM50306205(2-(4-(pyridin-4-ylmethylcarbamoyl)phenyl)-2H-indaz...)
Affinity DataIC50: 10nMAssay Description:Inhibition of human PARP1 after 3 hrs using [3H]NAD+ by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Irbm-Merck Research Laboratories Rome

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50306169BDBM50306169((R)-5-fluoro-2-(3-fluoro-4-(1-methylpiperidine-3-c...)
Affinity DataIC50: 12nMAssay Description:Inhibition of human PARP1 after 3 hrs using [3H]NAD+ by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Irbm-Merck Research Laboratories Rome

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50306185BDBM50306185(2-(3-hydroxy-4-((methylamino)methyl)phenyl)-2H-ind...)
Affinity DataIC50: 12nMAssay Description:Inhibition of human PARP1 after 3 hrs using [3H]NAD+ by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Irbm-Merck Research Laboratories Rome

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50306201BDBM50306201(2-(4-(2-(dimethylamino)acetamido)phenyl)-2H-indazo...)
Affinity DataIC50: 15nMAssay Description:Inhibition of human PARP1 after 3 hrs using [3H]NAD+ by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Irbm-Merck Research Laboratories Rome

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50306172BDBM50306172(5-fluoro-2-(4-(1-methylpiperidine-4-carboxamido)ph...)
Affinity DataIC50: 16nMAssay Description:Inhibition of human PARP1 after 3 hrs using [3H]NAD+ by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Irbm-Merck Research Laboratories Rome

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50306193BDBM50306193((S)-2-(4-(1-methylpyrrolidine-2-carboxamido)phenyl...)
Affinity DataIC50: 17nMAssay Description:Inhibition of human PARP1 after 3 hrs using [3H]NAD+ by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Irbm-Merck Research Laboratories Rome

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50306190BDBM50306190(2-(4-((N-methylazetidine-3-carboxamido)methyl)phen...)
Affinity DataIC50: 18nMAssay Description:Inhibition of human PARP1 after 3 hrs using [3H]NAD+ by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Irbm-Merck Research Laboratories Rome

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50306178BDBM50306178(6-fluoro-2-(4-((methylamino)methyl)phenyl)-2H-inda...)
Affinity DataIC50: 20nMAssay Description:Inhibition of human PARP1 after 3 hrs using [3H]NAD+ by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Irbm-Merck Research Laboratories Rome

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50306194BDBM50306194((S)-2-(4-(1-methylpiperidine-3-carboxamido)phenyl)...)
Affinity DataIC50: 20nMAssay Description:Inhibition of human PARP1 after 3 hrs using [3H]NAD+ by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Irbm-Merck Research Laboratories Rome

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50306208BDBM50306208(2-(4-(2-(pyrrolidin-1-yl)ethylcarbamoyl)phenyl)-2H...)
Affinity DataIC50: 20nMAssay Description:Inhibition of human PARP1 after 3 hrs using [3H]NAD+ by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Irbm-Merck Research Laboratories Rome

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50306183BDBM50306183(3-chloro-2-(4-((methylamino)methyl)phenyl)-2H-inda...)
Affinity DataIC50: 20nMAssay Description:Inhibition of human PARP1 after 3 hrs using [3H]NAD+ by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Irbm-Merck Research Laboratories Rome

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50306199BDBM50306199(2-(4-(2-(piperidin-1-yl)acetamido)phenyl)-2H-indaz...)
Affinity DataIC50: 20nMAssay Description:Inhibition of human PARP1 after 3 hrs using [3H]NAD+ by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Irbm-Merck Research Laboratories Rome

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50306189BDBM50306189(2-(4-((1-methylpiperidine-3-carboxamido)methyl)phe...)
Affinity DataIC50: 22nMAssay Description:Inhibition of human PARP1 after 3 hrs using [3H]NAD+ by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Irbm-Merck Research Laboratories Rome

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50306203BDBM50306203(2-(4-(1,4-diazepane-1-carbonyl)phenyl)-2H-indazole...)
Affinity DataIC50: 22nMAssay Description:Inhibition of human PARP1 after 3 hrs using [3H]NAD+ by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Irbm-Merck Research Laboratories Rome

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50306177BDBM50306177(4,5-difluoro-2-(4-((methylamino)methyl)phenyl)-2H-...)
Affinity DataIC50: 25nMAssay Description:Inhibition of human PARP1 after 3 hrs using [3H]NAD+ by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Irbm-Merck Research Laboratories Rome

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50306191BDBM50306191(2-(4-((N,1-dimethylpiperidine-3-carboxamido)methyl...)
Affinity DataIC50: 25nMAssay Description:Inhibition of human PARP1 after 3 hrs using [3H]NAD+ by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Irbm-Merck Research Laboratories Rome

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50306166BDBM50306166(2-phenyl-2H-indazole-7-carboxamide | CHEMBL594298)
Affinity DataIC50: 25nMAssay Description:Inhibition of human PARP1 after 3 hrs using [3H]NAD+ by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Irbm-Merck Research Laboratories Rome

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50306198BDBM50306198(2-(4-(2-morpholinoacetamido)phenyl)-2H-indazole-7-...)
Affinity DataIC50: 30nMAssay Description:Inhibition of human PARP1 after 3 hrs using [3H]NAD+ by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Irbm-Merck Research Laboratories Rome

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50306195BDBM50306195((R)-2-(4-(1-methylpiperidine-3-carboxamido)phenyl)...)
Affinity DataIC50: 30nMAssay Description:Inhibition of human PARP1 after 3 hrs using [3H]NAD+ by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Irbm-Merck Research Laboratories Rome

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50306204BDBM50306204(2-(4-(pyridin-4-ylcarbamoyl)phenyl)-2H-indazole-7-...)
Affinity DataIC50: 30nMAssay Description:Inhibition of human PARP1 after 3 hrs using [3H]NAD+ by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Irbm-Merck Research Laboratories Rome

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50306207BDBM50306207(2-(4-(2-(piperidin-1-yl)ethylcarbamoyl)phenyl)-2H-...)
Affinity DataIC50: 38nMAssay Description:Inhibition of human PARP1 after 3 hrs using [3H]NAD+ by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Irbm-Merck Research Laboratories Rome

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50306202BDBM50306202(2-(3-(1,4-diazepane-1-carbonyl)phenyl)-2H-indazole...)
Affinity DataIC50: 40nMAssay Description:Inhibition of human PARP1 after 3 hrs using [3H]NAD+ by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Irbm-Merck Research Laboratories Rome

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50306197BDBM50306197((+/-)-2-(4-(1-methylpiperidine-2-carboxamido)pheny...)
Affinity DataIC50: 46nMAssay Description:Inhibition of human PARP1 after 3 hrs using [3H]NAD+ by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Irbm-Merck Research Laboratories Rome

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50306206BDBM50306206(2-(4-(2-morpholinoethylcarbamoyl)phenyl)-2H-indazo...)
Affinity DataIC50: 54nMAssay Description:Inhibition of human PARP1 after 3 hrs using [3H]NAD+ by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Irbm-Merck Research Laboratories Rome

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50306188BDBM50306188(2-(4-((azetidine-3-carboxamido)methyl)phenyl)-2H-i...)
Affinity DataIC50: 65nMAssay Description:Inhibition of human PARP1 after 3 hrs using [3H]NAD+ by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Irbm-Merck Research Laboratories Rome

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50306182BDBM50306182(4-chloro-2-(4-((methylamino)methyl)phenyl)-2H-inda...)
Affinity DataIC50: 180nMAssay Description:Inhibition of human PARP1 after 3 hrs using [3H]NAD+ by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Irbm-Merck Research Laboratories Rome

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50306175BDBM50306175(4-hydroxy-2-(4-((methylamino)methyl)phenyl)-2H-ind...)
Affinity DataIC50: 540nMAssay Description:Inhibition of human PARP1 after 3 hrs using [3H]NAD+ by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Irbm-Merck Research Laboratories Rome

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50306176BDBM50306176(4-methoxy-2-(4-((methylamino)methyl)phenyl)-2H-ind...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human PARP1 after 3 hrs using [3H]NAD+ by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed