Compile Data Set for Download or QSAR
maximum 50k data
Found 21 Enz. Inhib. hit(s) with all data for entry = 50031280
TargetMAP kinase-activated protein kinase 2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50310343(6-(1-(3-(1H-indol-6-yl)phenyl)-3-amino-1H-pyrazol-...)
Affinity DataIC50:  61nMAssay Description:Inhibition of human MK2 by FRET assayMore data for this Ligand-Target Pair
TargetMAP kinase-activated protein kinase 2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50310342(6-(1-(3-(1H-benzo[d]imidazol-6-yl)phenyl)-3-amino-...)
Affinity DataIC50:  82nMAssay Description:Inhibition of human MK2 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMAP kinase-activated protein kinase 2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50310352(7-(3-amino-1-(4-methoxyphenyl)-1H-pyrazol-4-yl)-3,...)
Affinity DataIC50:  84nMAssay Description:Inhibition of human MK2 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMAP kinase-activated protein kinase 2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50310341(CHEMBL605125 | N-(3'-(3-amino-4-(1-oxo-1,2,3,4-tet...)
Affinity DataIC50:  180nMAssay Description:Inhibition of human MK2 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMAP kinase-activated protein kinase 2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50310355(6-(3-amino-1-(3'-hydroxybiphenyl-3-yl)-1H-pyrazol-...)
Affinity DataIC50:  180nMAssay Description:Inhibition of human MK2 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMAP kinase-activated protein kinase 2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50310356(6-(3-amino-1-(3'-methoxybiphenyl-3-yl)-1H-pyrazol-...)
Affinity DataIC50:  180nMAssay Description:Inhibition of human MK2 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMAP kinase-activated protein kinase 2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50310345(6-(3-amino-1-(3-(2-oxoindolin-6-yl)phenyl)-1H-pyra...)
Affinity DataIC50:  220nMAssay Description:Inhibition of human MK2 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMAP kinase-activated protein kinase 2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50310344(6-(3-amino-1-(3-(1-methyl-1H-indol-6-yl)phenyl)-1H...)
Affinity DataIC50:  290nMAssay Description:Inhibition of human MK2 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMAP kinase-activated protein kinase 2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50310354(7-(3-amino-1-(4-methoxyphenyl)-1H-pyrazol-4-yl)-3,...)
Affinity DataIC50:  350nMAssay Description:Inhibition of human MK2 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMAP kinase-activated protein kinase 2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM30311(Pyrrolo-pyrimidone, 4)
Affinity DataIC50:  540nMAssay Description:Inhibition of human MK2 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMAP kinase-activated protein kinase 2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50310353(8-(3-amino-1-(4-methoxyphenyl)-1H-pyrazol-4-yl)-2,...)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of human MK2 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMAP kinase-activated protein kinase 2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50310347(4-(3-amino-1-(4-methoxyphenyl)-1H-pyrazol-4-yl)ben...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of human MK2 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMAP kinase-activated protein kinase 2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50310351(5-(3-amino-1-(4-methoxyphenyl)-1H-pyrazol-4-yl)iso...)
Affinity DataIC50:  6.00E+3nMAssay Description:Inhibition of human MK2 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50310343(6-(1-(3-(1H-indol-6-yl)phenyl)-3-amino-1H-pyrazol-...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of p38alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50310343(6-(1-(3-(1H-indol-6-yl)phenyl)-3-amino-1H-pyrazol-...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of JNK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 9(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50310343(6-(1-(3-(1H-indol-6-yl)phenyl)-3-amino-1H-pyrazol-...)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of JNK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50310343(6-(1-(3-(1H-indol-6-yl)phenyl)-3-amino-1H-pyrazol-...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CDK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMAP kinase-activated protein kinase 2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50310350(4-(3-amino-1-(4-methoxyphenyl)-1H-pyrazol-4-yl)ben...)
Affinity DataIC50:  1.54E+4nMAssay Description:Inhibition of human MK2 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMAP kinase-activated protein kinase 2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50310348(4-(5-amino-1-(4-methoxyphenyl)-1H-pyrazol-4-yl)ben...)
Affinity DataIC50:  2.25E+4nMAssay Description:Inhibition of human MK2 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMAP kinase-activated protein kinase 2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50310346(4-(1-(4-methoxyphenyl)-1H-pyrazol-4-yl)benzamide |...)
Affinity DataIC50:  2.26E+4nMAssay Description:Inhibition of human MK2 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMAP kinase-activated protein kinase 2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50310349(4-(3-amino-1-(4-methoxyphenyl)-1H-pyrazol-4-yl)ben...)
Affinity DataIC50:  3.12E+4nMAssay Description:Inhibition of human MK2 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed