Compile Data Set for Download or QSAR
maximum 50k data
Found 6 Enz. Inhib. hit(s) with all data for entry = 50032052
TargetTransthyretin(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50323722(4-fluorophenyl 3-(4-hydroxy-3,5-dimethylstyryl)ben...)
Affinity DataIC50:  1.96E+3nMpH: 4.4Assay Description:Inhibition of wild type TTR amyloidogenesis assessed as inhibition of fibril formation after 72 hrs at pH 4.4 by spectrophotometry relative to untrea...More data for this Ligand-Target Pair
TargetTransthyretin(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50323724(CHEMBL1213660 | S-phenyl 3-(4-hydroxy-3,5-dimethyl...)
Affinity DataIC50:  2.00E+3nMpH: 4.4Assay Description:Inhibition of wild type TTR amyloidogenesis assessed as inhibition of fibril formation after 72 hrs at pH 4.4 by spectrophotometry relative to untrea...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransthyretin(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50323725(CHEMBL1213659 | S-phenyl 3-(3,5-dibromo-4-hydroxys...)
Affinity DataIC50:  2.00E+3nMpH: 4.4Assay Description:Inhibition of wild type TTR amyloidogenesis assessed as inhibition of fibril formation after 72 hrs at pH 4.4 by spectrophotometry relative to untrea...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransthyretin(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50323723(2-nitrophenyl 3-(4-hydroxy-3,5-dimethylstyryl)benz...)
Affinity DataIC50:  2.26E+3nMpH: 4.4Assay Description:Inhibition of wild type TTR amyloidogenesis assessed as inhibition of fibril formation after 72 hrs at pH 4.4 by spectrophotometry relative to untrea...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransthyretin(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50012781(3-(4-hydroxy-3,5-dimethylstyryl)benzoic acid | 3-[...)
Affinity DataIC50:  3.07E+3nMpH: 4.4Assay Description:Inhibition of wild type TTR amyloidogenesis assessed as inhibition of fibril formation after 72 hrs at pH 4.4 by spectrophotometry relative to untrea...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransthyretin(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50012798((E)-2,6-dimethyl-4-styrylphenol | 2,6-Dimethyl-4-s...)
Affinity DataIC50:  3.08E+3nMpH: 4.4Assay Description:Inhibition of wild type TTR amyloidogenesis assessed as inhibition of fibril formation after 72 hrs at pH 4.4 by spectrophotometry relative to untrea...More data for this Ligand-Target Pair