Compile Data Set for Download or QSAR
maximum 50k data
Found 46 Enz. Inhib. hit(s) with all data for entry = 50031082
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50306640(1-(4-(4-(8-oxa-3-azabicyclo[3.2.1]octan-3-yl)-1-(1...)
Affinity DataIC50:  0.120nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50306639(1-(4-(4-(8-oxa-3-azabicyclo[3.2.1]octan-3-yl)-1-(1...)
Affinity DataIC50:  0.120nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50306624(1-(4-(4-(8-oxa-3-azabicyclo[3.2.1]octan-3-yl)-1-is...)
Affinity DataIC50:  0.120nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50306638(1-(4-(4-(8-oxa-3-azabicyclo[3.2.1]octan-3-yl)-1-(1...)
Affinity DataIC50:  0.160nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50306620(CHEMBL606423 | isopropyl 4-(4-(8-oxa-3-azabicyclo[...)
Affinity DataIC50:  0.190nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50306633(1-(4-(4-(8-oxa-3-azabicyclo[3.2.1]octan-3-yl)-1-(1...)
Affinity DataIC50:  0.210nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50300066(CHEMBL568259 | methyl 4-(4-(8-oxa-3-azabicyclo[3.2...)
Affinity DataIC50:  0.220nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50306637(1-(4-(4-(8-oxa-3-azabicyclo[3.2.1]octan-3-yl)-1-(1...)
Affinity DataIC50:  0.220nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50306636(1-(4-(4-(8-oxa-3-azabicyclo[3.2.1]octan-3-yl)-1-(1...)
Affinity DataIC50:  0.220nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50306627(1-(4-(4-(8-oxa-3-azabicyclo[3.2.1]octan-3-yl)-1-(4...)
Affinity DataIC50:  0.220nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50306628(CHEMBL610630 | trans-1-(4-(4-(8-oxa-3-azabicyclo[3...)
Affinity DataIC50:  0.240nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50306635(1-(4-(4-(8-oxa-3-azabicyclo[3.2.1]octan-3-yl)-1-(1...)
Affinity DataIC50:  0.260nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50306621(CHEMBL600084 | tert-butyl 4-(4-(8-oxa-3-azabicyclo...)
Affinity DataIC50:  0.260nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50306629(CHEMBL606621 | cis-1-(4-(4-(8-oxa-3-azabicyclo[3.2...)
Affinity DataIC50:  0.300nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50306631(CHEMBL601445 | cis-1-(4-(4-(8-oxa-3-azabicyclo[3.2...)
Affinity DataIC50:  0.330nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50306630(CHEMBL602276 | trans-1-(4-(4-(8-oxa-3-azabicyclo[3...)
Affinity DataIC50:  0.380nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50300097(1-(4-(4-(8-oxa-3-azabicyclo[3.2.1]octan-3-yl)-1-(2...)
Affinity DataIC50:  0.5nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50306632(1-(4-(4-(8-oxa-3-azabicyclo[3.2.1]octan-3-yl)-1-(4...)
Affinity DataIC50:  0.740nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50306623(1-(4-(4-(8-oxa-3-azabicyclo[3.2.1]octan-3-yl)-1-et...)
Affinity DataIC50:  0.740nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50306634(1-(4-(4-(8-oxa-3-azabicyclo[3.2.1]octan-3-yl)-1-(1...)
Affinity DataIC50:  1.19nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50306622(1-(4-(4-(8-oxa-3-azabicyclo[3.2.1]octan-3-yl)-1-me...)
Affinity DataIC50:  1.34nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50306625(1-(4-(4-(8-oxa-3-azabicyclo[3.2.1]octan-3-yl)-1-(2...)
Affinity DataIC50:  2.85nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50306626(1-(4-(4-(8-oxa-3-azabicyclo[3.2.1]octan-3-yl)-1-(2...)
Affinity DataIC50:  14.5nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50306639(1-(4-(4-(8-oxa-3-azabicyclo[3.2.1]octan-3-yl)-1-(1...)
Affinity DataIC50:  220nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50306629(CHEMBL606621 | cis-1-(4-(4-(8-oxa-3-azabicyclo[3.2...)
Affinity DataIC50:  227nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50306624(1-(4-(4-(8-oxa-3-azabicyclo[3.2.1]octan-3-yl)-1-is...)
Affinity DataIC50:  234nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50306622(1-(4-(4-(8-oxa-3-azabicyclo[3.2.1]octan-3-yl)-1-me...)
Affinity DataIC50:  247nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50306623(1-(4-(4-(8-oxa-3-azabicyclo[3.2.1]octan-3-yl)-1-et...)
Affinity DataIC50:  270nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50306640(1-(4-(4-(8-oxa-3-azabicyclo[3.2.1]octan-3-yl)-1-(1...)
Affinity DataIC50:  270nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50306634(1-(4-(4-(8-oxa-3-azabicyclo[3.2.1]octan-3-yl)-1-(1...)
Affinity DataIC50:  305nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50306638(1-(4-(4-(8-oxa-3-azabicyclo[3.2.1]octan-3-yl)-1-(1...)
Affinity DataIC50:  353nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50306625(1-(4-(4-(8-oxa-3-azabicyclo[3.2.1]octan-3-yl)-1-(2...)
Affinity DataIC50:  375nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50306632(1-(4-(4-(8-oxa-3-azabicyclo[3.2.1]octan-3-yl)-1-(4...)
Affinity DataIC50:  648nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50306631(CHEMBL601445 | cis-1-(4-(4-(8-oxa-3-azabicyclo[3.2...)
Affinity DataIC50:  705nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50306628(CHEMBL610630 | trans-1-(4-(4-(8-oxa-3-azabicyclo[3...)
Affinity DataIC50:  882nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50306626(1-(4-(4-(8-oxa-3-azabicyclo[3.2.1]octan-3-yl)-1-(2...)
Affinity DataIC50:  966nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50306630(CHEMBL602276 | trans-1-(4-(4-(8-oxa-3-azabicyclo[3...)
Affinity DataIC50:  1.17E+3nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50306633(1-(4-(4-(8-oxa-3-azabicyclo[3.2.1]octan-3-yl)-1-(1...)
Affinity DataIC50:  1.18E+3nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50306627(1-(4-(4-(8-oxa-3-azabicyclo[3.2.1]octan-3-yl)-1-(4...)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50306621(CHEMBL600084 | tert-butyl 4-(4-(8-oxa-3-azabicyclo...)
Affinity DataIC50:  1.48E+3nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50300097(1-(4-(4-(8-oxa-3-azabicyclo[3.2.1]octan-3-yl)-1-(2...)
Affinity DataIC50:  1.62E+3nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50300066(CHEMBL568259 | methyl 4-(4-(8-oxa-3-azabicyclo[3.2...)
Affinity DataIC50:  1.80E+3nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50306620(CHEMBL606423 | isopropyl 4-(4-(8-oxa-3-azabicyclo[...)
Affinity DataIC50:  2.02E+3nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50306635(1-(4-(4-(8-oxa-3-azabicyclo[3.2.1]octan-3-yl)-1-(1...)
Affinity DataIC50:  4.58E+3nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50306636(1-(4-(4-(8-oxa-3-azabicyclo[3.2.1]octan-3-yl)-1-(1...)
Affinity DataIC50:  5.13E+3nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50306637(1-(4-(4-(8-oxa-3-azabicyclo[3.2.1]octan-3-yl)-1-(1...)
Affinity DataIC50:  1.20E+4nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed