Compile Data Set for Download or QSAR
Report error Found 8 Enz. Inhib. hit(s) with all data for entry = 50039112
TargetDihydrofolate reductase(Human)
Duquesne University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 18050BDBM18050(MTX | cid_126941 | Methotrexate | 2-[(4-{[(2,4-dia...)
Affinity DataIC50: 22nMAssay Description:Inhibition of human DHFRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2012
Entry Details Article
PubMed
TargetThymidylate synthase(Human)
Duquesne University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 18795BDBM18795((2S)-2-[(5-{methyl[(2-methyl-4-oxo-1,4-dihydroquin...)
Affinity DataIC50: 290nMAssay Description:Inhibition of human thymidylate synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2012
Entry Details Article
PubMed
TargetThymidylate synthase(Human)
Duquesne University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50314077BDBM50314077(5-(p-tolylthio)-9H-pyrimido[4,5-b]indole-2,4-diami...)
Affinity DataIC50: 390nMAssay Description:Inhibition of human thymidylate synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2012
Entry Details Article
PubMed
TargetThymidylate synthase(Human)
Duquesne University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50314076BDBM50314076(5-(phenylthio)-9H-pyrimido[4,5-b]indole-2,4-diamin...)
Affinity DataIC50: 540nMAssay Description:Inhibition of human thymidylate synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2012
Entry Details Article
PubMed
TargetThymidylate synthase(Human)
Duquesne University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 18796BDBM18796((2S)-2-{[4-(2-{2-amino-4-oxo-1H,4H,7H-pyrrolo[2,3-...)
Affinity DataIC50: 2.90E+4nMAssay Description:Inhibition of human thymidylate synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2012
Entry Details Article
PubMed
TargetDihydrofolate reductase(Human)
Duquesne University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50314077BDBM50314077(5-(p-tolylthio)-9H-pyrimido[4,5-b]indole-2,4-diami...)
Affinity DataIC50: 3.10E+4nMAssay Description:Inhibition of human DHFRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2012
Entry Details Article
PubMed
TargetDihydrofolate reductase(Human)
Duquesne University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50314076BDBM50314076(5-(phenylthio)-9H-pyrimido[4,5-b]indole-2,4-diamin...)
Affinity DataIC50: 3.30E+4nMAssay Description:Inhibition of human DHFRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2012
Entry Details Article
PubMed
TargetDihydrofolate reductase(Human)
Duquesne University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 18069BDBM18069(CHEMBL22 | TMP | Trimethoprim (TMP) | 5-[(3,4,5-tr...)
Affinity DataIC50: 6.80E+5nMAssay Description:Inhibition of human DHFRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)