Compile Data Set for Download or QSAR
Report error Found 218 Enz. Inhib. hit(s) with all data for entry = 50031409
LigandChemical structure of BindingDB Monomer ID 50312778BDBM50312778((S)-(4-(1H-indole-6-carbonyl)-3-methylpiperazin-1-...)
Affinity DataIC50: 2nMAssay Description:Inhibition of rat GHSR expressed in CHOK1 cells assessed as inhibition of ghrelin-induced intracellular calcium flux by aequorin flash luminescence a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50312779BDBM50312779((S)-(4-(1H-indole-6-carbonyl)-3-methylpiperazin-1-...)
Affinity DataIC50: 2.10nMAssay Description:Antagonist activity at human GHSR expressed in CHOK1 cells assessed as inhibition of ghrelin-induced intracellular calcium flux by aequorin flash lum...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50312766BDBM50312766((S)-(4-(1H-indole-6-carbonyl)-3-methylpiperazin-1-...)
Affinity DataIC50: 2.90nMAssay Description:Antagonist activity at human GHSR expressed in CHOK1 cells assessed as inhibition of ghrelin-induced intracellular calcium flux by aequorin flash lum...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50312780BDBM50312780((S)-(4-(1H-indole-6-carbonyl)-3-methylpiperazin-1-...)
Affinity DataIC50: 4.10nMAssay Description:Antagonist activity at human GHSR expressed in CHOK1 cells assessed as inhibition of ghrelin-induced intracellular calcium flux by aequorin flash lum...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50312776BDBM50312776((S)-(4-(1H-indole-6-carbonyl)-3-methylpiperazin-1-...)
Affinity DataIC50: 6nMAssay Description:Antagonist activity at human GHSR expressed in CHOK1 cells assessed as inhibition of ghrelin-induced intracellular calcium flux by aequorin flash lum...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50312767BDBM50312767((S)-(4-(1H-indole-6-carbonyl)-3-methylpiperazin-1-...)
Affinity DataIC50: 7nMAssay Description:Antagonist activity at human GHSR expressed in CHOK1 cells assessed as inhibition of ghrelin-induced intracellular calcium flux by aequorin flash lum...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50312787BDBM50312787(((S)-4-(1H-indole-6-carbonyl)-3-methylpiperazin-1-...)
Affinity DataIC50: 9nMAssay Description:Antagonist activity at human GHSR expressed in CHOK1 cells assessed as inhibition of ghrelin-induced intracellular calcium flux by aequorin flash lum...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50312778BDBM50312778((S)-(4-(1H-indole-6-carbonyl)-3-methylpiperazin-1-...)
Affinity DataIC50: 9.10nMAssay Description:Antagonist activity at human GHSR expressed in CHOK1 cells assessed as inhibition of ghrelin-induced intracellular calcium flux by aequorin flash lum...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50312771BDBM50312771((S)-(4-(1H-indole-6-carbonyl)-3-methylpiperazin-1-...)
Affinity DataIC50: 12nMAssay Description:Antagonist activity at human GHSR expressed in CHOK1 cells assessed as inhibition of ghrelin-induced intracellular calcium flux by aequorin flash lum...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50312799BDBM50312799((S)-(4-(1H-indole-6-carbonyl)-3-methylpiperazin-1-...)
Affinity DataIC50: 12.2nMAssay Description:Antagonist activity at human GHSR expressed in CHOK1 cells assessed as inhibition of ghrelin-induced intracellular calcium flux by aequorin flash lum...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50312792BDBM50312792((S)-(4-(1H-indole-6-carbonyl)-3-methylpiperazin-1-...)
Affinity DataIC50: 12.7nMAssay Description:Antagonist activity at human GHSR expressed in CHOK1 cells assessed as inhibition of ghrelin-induced intracellular calcium flux by aequorin flash lum...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50312789BDBM50312789((S)-(4-(1H-indole-6-carbonyl)-3-methylpiperazin-1-...)
Affinity DataIC50: 13nMAssay Description:Antagonist activity at human GHSR expressed in CHOK1 cells assessed as inhibition of ghrelin-induced intracellular calcium flux by aequorin flash lum...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50312786BDBM50312786((S)-(4-(1H-indole-6-carbonyl)-3-methylpiperazin-1-...)
Affinity DataIC50: 14.3nMAssay Description:Antagonist activity at human GHSR expressed in CHOK1 cells assessed as inhibition of ghrelin-induced intracellular calcium flux by aequorin flash lum...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50312785BDBM50312785((S)-(4-(1H-indole-6-carbonyl)-3-methylpiperazin-1-...)
Affinity DataIC50: 17.7nMAssay Description:Antagonist activity at human GHSR expressed in CHOK1 cells assessed as inhibition of ghrelin-induced intracellular calcium flux by aequorin flash lum...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50312788BDBM50312788((S)-(4-(1H-indole-6-carbonyl)-3-methylpiperazin-1-...)
Affinity DataIC50: 20nMAssay Description:Antagonist activity at human GHSR expressed in CHOK1 cells assessed as inhibition of ghrelin-induced intracellular calcium flux by aequorin flash lum...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50312781BDBM50312781((4-(1H-indole-6-carbonyl)piperazin-1-yl)(3'-methox...)
Affinity DataIC50: 25nMAssay Description:Antagonist activity at human GHSR expressed in CHOK1 cells assessed as inhibition of ghrelin-induced intracellular calcium flux by aequorin flash lum...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50312777BDBM50312777((S)-(4-(1H-indole-6-carbonyl)-3-methylpiperazin-1-...)
Affinity DataIC50: 26nMAssay Description:Antagonist activity at human GHSR expressed in CHOK1 cells assessed as inhibition of ghrelin-induced intracellular calcium flux by aequorin flash lum...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50312801BDBM50312801((S)-(4-(1H-indole-6-carbonyl)-3-methylpiperazin-1-...)
Affinity DataIC50: 31nMAssay Description:Antagonist activity at human GHSR expressed in CHOK1 cells assessed as inhibition of ghrelin-induced intracellular calcium flux by aequorin flash lum...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50312791BDBM50312791((S)-(4-(1H-indole-6-carbonyl)-3-methylpiperazin-1-...)
Affinity DataIC50: 33.7nMAssay Description:Antagonist activity at human GHSR expressed in CHOK1 cells assessed as inhibition of ghrelin-induced intracellular calcium flux by aequorin flash lum...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50312790BDBM50312790((S)-(4-(1H-indole-6-carbonyl)-3-methylpiperazin-1-...)
Affinity DataIC50: 37.2nMAssay Description:Antagonist activity at human GHSR expressed in CHOK1 cells assessed as inhibition of ghrelin-induced intracellular calcium flux by aequorin flash lum...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50312800BDBM50312800(((S)-4-(1H-indole-6-carbonyl)-3-methylpiperazin-1-...)
Affinity DataIC50: 42nMAssay Description:Antagonist activity at human GHSR expressed in CHOK1 cells assessed as inhibition of ghrelin-induced intracellular calcium flux by aequorin flash lum...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50312793BDBM50312793((S)-(4-(1H-indole-6-carbonyl)-3-methylpiperazin-1-...)
Affinity DataIC50: 42.2nMAssay Description:Antagonist activity at human GHSR expressed in CHOK1 cells assessed as inhibition of ghrelin-induced intracellular calcium flux by aequorin flash lum...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50312773BDBM50312773((S)-(4-(1H-indole-6-carbonyl)-3-methylpiperazin-1-...)
Affinity DataIC50: 46.5nMAssay Description:Antagonist activity at human GHSR expressed in CHOK1 cells assessed as inhibition of ghrelin-induced intracellular calcium flux by aequorin flash lum...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50312769BDBM50312769((S)-(4-(1H-indole-6-carbonyl)-3-methylpiperazin-1-...)
Affinity DataIC50: 64nMAssay Description:Antagonist activity at human GHSR expressed in CHOK1 cells assessed as inhibition of ghrelin-induced intracellular calcium flux by aequorin flash lum...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50312795BDBM50312795((S)-(4-(1H-indole-6-carbonyl)-3-methylpiperazin-1-...)
Affinity DataIC50: 65nMAssay Description:Antagonist activity at human GHSR expressed in CHOK1 cells assessed as inhibition of ghrelin-induced intracellular calcium flux by aequorin flash lum...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50312783BDBM50312783((R)-(4-(1H-indole-6-carbonyl)-2-methylpiperazin-1-...)
Affinity DataIC50: 68nMAssay Description:Antagonist activity at human GHSR expressed in CHOK1 cells assessed as inhibition of ghrelin-induced intracellular calcium flux by aequorin flash lum...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50312774BDBM50312774((S)-(4-(1H-indole-6-carbonyl)-3-methylpiperazin-1-...)
Affinity DataIC50: 77nMAssay Description:Antagonist activity at human GHSR expressed in CHOK1 cells assessed as inhibition of ghrelin-induced intracellular calcium flux by aequorin flash lum...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50312770BDBM50312770((4-(1H-indole-6-carbonyl)piperazin-1-yl)(biphenyl-...)
Affinity DataIC50: 100nMAssay Description:Antagonist activity at human GHSR expressed in CHOK1 cells assessed as inhibition of ghrelin-induced intracellular calcium flux by aequorin flash lum...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50312797BDBM50312797((S)-(4-(1H-indole-6-carbonyl)-3-methylpiperazin-1-...)
Affinity DataIC50: 123nMAssay Description:Antagonist activity at human GHSR expressed in CHOK1 cells assessed as inhibition of ghrelin-induced intracellular calcium flux by aequorin flash lum...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50312768BDBM50312768((S)-(4-(1H-indole-6-carbonyl)-3-methylpiperazin-1-...)
Affinity DataIC50: 136nMAssay Description:Antagonist activity at human GHSR expressed in CHOK1 cells assessed as inhibition of ghrelin-induced intracellular calcium flux by aequorin flash lum...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50312794BDBM50312794((S)-(4-(1H-indole-6-carbonyl)-3-methylpiperazin-1-...)
Affinity DataIC50: 143nMAssay Description:Antagonist activity at human GHSR expressed in CHOK1 cells assessed as inhibition of ghrelin-induced intracellular calcium flux by aequorin flash lum...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50312775BDBM50312775((S)-(4-(1H-indole-6-carbonyl)-3-methylpiperazin-1-...)
Affinity DataIC50: 147nMAssay Description:Antagonist activity at human GHSR expressed in CHOK1 cells assessed as inhibition of ghrelin-induced intracellular calcium flux by aequorin flash lum...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50312796BDBM50312796((S)-(4-(1H-indole-6-carbonyl)-3-methylpiperazin-1-...)
Affinity DataIC50: 245nMAssay Description:Antagonist activity at human GHSR expressed in CHOK1 cells assessed as inhibition of ghrelin-induced intracellular calcium flux by aequorin flash lum...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50312782BDBM50312782((S)-(4-(1H-indole-6-carbonyl)-2-methylpiperazin-1-...)
Affinity DataIC50: 280nMAssay Description:Antagonist activity at human GHSR expressed in CHOK1 cells assessed as inhibition of ghrelin-induced intracellular calcium flux by aequorin flash lum...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50312798BDBM50312798((S)-(4-(1H-indole-6-carbonyl)-3-methylpiperazin-1-...)
Affinity DataIC50: 339nMAssay Description:Antagonist activity at human GHSR expressed in CHOK1 cells assessed as inhibition of ghrelin-induced intracellular calcium flux by aequorin flash lum...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50312772BDBM50312772((R)-(4-(1H-indole-6-carbonyl)-3-methylpiperazin-1-...)
Affinity DataIC50: 640nMAssay Description:Antagonist activity at human GHSR expressed in CHOK1 cells assessed as inhibition of ghrelin-induced intracellular calcium flux by aequorin flash lum...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50312784BDBM50312784((4-(1H-indole-6-carbonyl)-1,4-diazepan-1-yl)(biphe...)
Affinity DataIC50: 6.50E+3nMAssay Description:Antagonist activity at human GHSR expressed in CHOK1 cells assessed as inhibition of ghrelin-induced intracellular calcium flux by aequorin flash lum...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50312775BDBM50312775((S)-(4-(1H-indole-6-carbonyl)-3-methylpiperazin-1-...)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of NETMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50312774BDBM50312774((S)-(4-(1H-indole-6-carbonyl)-3-methylpiperazin-1-...)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of NETMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50312773BDBM50312773((S)-(4-(1H-indole-6-carbonyl)-3-methylpiperazin-1-...)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of NETMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50312772BDBM50312772((R)-(4-(1H-indole-6-carbonyl)-3-methylpiperazin-1-...)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of NETMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50312779BDBM50312779((S)-(4-(1H-indole-6-carbonyl)-3-methylpiperazin-1-...)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of NETMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50312778BDBM50312778((S)-(4-(1H-indole-6-carbonyl)-3-methylpiperazin-1-...)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of NETMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50312777BDBM50312777((S)-(4-(1H-indole-6-carbonyl)-3-methylpiperazin-1-...)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of NETMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50312776BDBM50312776((S)-(4-(1H-indole-6-carbonyl)-3-methylpiperazin-1-...)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of NETMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50312768BDBM50312768((S)-(4-(1H-indole-6-carbonyl)-3-methylpiperazin-1-...)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of NETMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50312767BDBM50312767((S)-(4-(1H-indole-6-carbonyl)-3-methylpiperazin-1-...)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of NETMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50312766BDBM50312766((S)-(4-(1H-indole-6-carbonyl)-3-methylpiperazin-1-...)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of NETMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50312780BDBM50312780((S)-(4-(1H-indole-6-carbonyl)-3-methylpiperazin-1-...)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of NETMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetHistamine H2 receptor(Human)
Amgen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50312772BDBM50312772((R)-(4-(1H-indole-6-carbonyl)-3-methylpiperazin-1-...)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of histamine H2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
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