Compile Data Set for Download or QSAR
Report error Found 32 Enz. Inhib. hit(s) with all data for entry = 50031447
TargetCathepsin K(Human)
Schering-Plough

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50313524BDBM50313524(3,5-dioxo-4-(3-piperidin-1-ylpropyl)-2-[3-(trifluo...)
Affinity DataIC50: 17nMAssay Description:Inhibition of human recombinant cathepsin K by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCathepsin K(Human)
Schering-Plough

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50313531BDBM50313531(2-(3-isopropylphenyl)-3,5-dioxo-4-(3-(piperidin-1-...)
Affinity DataIC50: 38nMAssay Description:Inhibition of human recombinant cathepsin K by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetCathepsin K(Human)
Schering-Plough

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50313514BDBM50313514(2-cycloheptyl-3,5-dioxo-4-propyl-2,3,4,5-tetrahydr...)
Affinity DataIC50: 38nMAssay Description:Inhibition of human recombinant cathepsin K by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetCathepsin K(Human)
Schering-Plough

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50313507BDBM50313507(2-(3-isopropylphenyl)-3,5-dioxo-4-propyl-2,3,4,5-t...)
Affinity DataIC50: 72nMAssay Description:Inhibition of human recombinant cathepsin K by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetCathepsin K(Human)
Schering-Plough

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50313523BDBM50313523(4-(3-(dimethylamino)propyl)-3,5-dioxo-2-(3-(triflu...)
Affinity DataIC50: 100nMAssay Description:Inhibition of human recombinant cathepsin K by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetCathepsin K(Human)
Schering-Plough

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50313529BDBM50313529(2-cycloheptyl-3,5-dioxo-4-(3-(piperidin-1-yl)propy...)
Affinity DataIC50: 100nMAssay Description:Inhibition of human recombinant cathepsin K by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetCathepsin K(Human)
Schering-Plough

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50313528BDBM50313528(2-cycloheptyl-4-(3-(dimethylamino)propyl)-3,5-diox...)
Affinity DataIC50: 110nMAssay Description:Inhibition of human recombinant cathepsin K by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetCathepsin K(Human)
Schering-Plough

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50313527BDBM50313527(4-(3-morpholinopropyl)-3,5-dioxo-2-(3-(trifluorome...)
Affinity DataIC50: 112nMAssay Description:Inhibition of human recombinant cathepsin K by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetCathepsin K(Human)
Schering-Plough

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50313525BDBM50313525(3,5-dioxo-4-(2-(piperidin-1-yl)ethyl)-2-(3-(triflu...)
Affinity DataIC50: 182nMAssay Description:Inhibition of human recombinant cathepsin K by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetCathepsin K(Human)
Schering-Plough

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50313513BDBM50313513(2-cyclohexyl-3,5-dioxo-4-propyl-2,3,4,5-tetrahydro...)
Affinity DataIC50: 197nMAssay Description:Inhibition of human recombinant cathepsin K by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetCathepsin K(Human)
Schering-Plough

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50313508BDBM50313508(2-(3-tert-butylphenyl)-3,5-dioxo-4-propyl-2,3,4,5-...)
Affinity DataIC50: 288nMAssay Description:Inhibition of human recombinant cathepsin K by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetCathepsin K(Human)
Schering-Plough

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50313530BDBM50313530(2-cycloheptyl-4-(3-morpholinopropyl)-3,5-dioxo-2,3...)
Affinity DataIC50: 500nMAssay Description:Inhibition of human recombinant cathepsin K by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetCathepsin K(Human)
Schering-Plough

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50313526BDBM50313526(4-(2-(dimethylamino)ethyl)-3,5-dioxo-2-(3-(trifluo...)
Affinity DataIC50: 810nMAssay Description:Inhibition of human recombinant cathepsin K by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetCathepsin K(Human)
Schering-Plough

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50313512BDBM50313512(2-cyclopentyl-3,5-dioxo-4-propyl-2,3,4,5-tetrahydr...)
Affinity DataIC50: 870nMAssay Description:Inhibition of human recombinant cathepsin K by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetCathepsin K(Human)
Schering-Plough

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50313521BDBM50313521(4-benzyl-3,5-dioxo-2-(3-(trifluoromethyl)phenyl)-2...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human recombinant cathepsin K by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetCathepsin K(Human)
Schering-Plough

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50313515BDBM50313515(2-(cyclohexylmethyl)-3,5-dioxo-4-propyl-2,3,4,5-te...)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of human recombinant cathepsin K by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetCathepsin K(Human)
Schering-Plough

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50313503BDBM50313503(3,5-dioxo-4-propyl-2-(3-(trifluoromethyl)phenyl)-2...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of human recombinant cathepsin K by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetCathepsin K(Human)
Schering-Plough

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50313519BDBM50313519(4-cyclopentyl-3,5-dioxo-2-(3-(trifluoromethyl)phen...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of human recombinant cathepsin K by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetCathepsin K(Human)
Schering-Plough

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50313517BDBM50313517(4-ethyl-3,5-dioxo-2-(3-(trifluoromethyl)phenyl)-2,...)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of human recombinant cathepsin K by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetCathepsin K(Human)
Schering-Plough

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50313506BDBM50313506(3,5-dioxo-4-propyl-2-m-tolyl-2,3,4,5-tetrahydro-1,...)
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of human recombinant cathepsin K by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetCathepsin K(Human)
Schering-Plough

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50313522BDBM50313522(3,5-dioxo-4-phenethyl-2-(3-(trifluoromethyl)phenyl...)
Affinity DataIC50: 4.46E+3nMAssay Description:Inhibition of human recombinant cathepsin K by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetCathepsin K(Human)
Schering-Plough

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50313518BDBM50313518(4-methyl-3,5-dioxo-2-(3-(trifluoromethyl)phenyl)-2...)
Affinity DataIC50: 4.78E+3nMAssay Description:Inhibition of human recombinant cathepsin K by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetCathepsin K(Human)
Schering-Plough

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50313516BDBM50313516(4-butyl-3,5-dioxo-2-(3-(trifluoromethyl)phenyl)-2,...)
Affinity DataIC50: 7.40E+3nMAssay Description:Inhibition of human recombinant cathepsin K by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetProcathepsin L(Human)
Schering-Plough

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50313524BDBM50313524(3,5-dioxo-4-(3-piperidin-1-ylpropyl)-2-[3-(trifluo...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of cathepsin LMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetCathepsin B(Human)
Schering-Plough

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50313524BDBM50313524(3,5-dioxo-4-(3-piperidin-1-ylpropyl)-2-[3-(trifluo...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of cathepsin BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetCathepsin K(Human)
Schering-Plough

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50313505BDBM50313505(3,5-dioxo-2-phenyl-4-propyl-2,3,4,5-tetrahydro-1,2...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant cathepsin K by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetCathepsin K(Human)
Schering-Plough

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50313504BDBM50313504(3,5-dioxo-4-propyl-2-(4-(trifluoromethyl)phenyl)-2...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant cathepsin K by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetCathepsin S(Human)
Schering-Plough

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50313524BDBM50313524(3,5-dioxo-4-(3-piperidin-1-ylpropyl)-2-[3-(trifluo...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of cathepsin SMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetCathepsin K(Human)
Schering-Plough

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50313509BDBM50313509(2-(biphenyl-3-yl)-3,5-dioxo-4-propyl-2,3,4,5-tetra...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant cathepsin K by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetCathepsin K(Human)
Schering-Plough

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50313511BDBM50313511(2-(3-(hydroxymethyl)phenyl)-3,5-dioxo-4-propyl-2,3...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant cathepsin K by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetCathepsin K(Human)
Schering-Plough

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50313510BDBM50313510(2-(3-methoxyphenyl)-3,5-dioxo-4-propyl-2,3,4,5-tet...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant cathepsin K by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetCathepsin K(Human)
Schering-Plough

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50313520BDBM50313520(3,5-dioxo-4-phenyl-2-(3-(trifluoromethyl)phenyl)-2...)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of human recombinant cathepsin K by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed