Compile Data Set for Download or QSAR
Report error Found 34 Enz. Inhib. hit(s) with all data for entry = 50031479
TargetCorticotropin-releasing factor receptor 1(Human)
Bristol-Myers Squibb Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50314008BDBM50314008(N-(cyclopropylmethyl)-2,2,2-trifluoro-N-((8-mesity...)
Affinity DataKi:  8nMAssay Description:Displacement of [125I]Tyr-o-CRF from human CRFR1 expressed in human IMR32 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Bristol-Myers Squibb Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50314009BDBM50314009(N-(cyclopropylmethyl)-2,2,3,3,3-pentafluoro-N-((8-...)
Affinity DataKi:  14nMAssay Description:Displacement of [125I]Tyr-o-CRF from human CRFR1 expressed in human IMR32 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Bristol-Myers Squibb Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50314010BDBM50314010(N,N-diallyl-8-mesityl-2-(trifluoromethyl)-5,6,7,8-...)
Affinity DataKi:  19nMAssay Description:Displacement of [125I]Tyr-o-CRF from human CRFR1 expressed in human IMR32 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Bristol-Myers Squibb Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50314011BDBM50314011(N-(cyclobutylmethyl)-N-((8-mesityl-2-(trifluoromet...)
Affinity DataKi:  21nMAssay Description:Displacement of [125I]Tyr-o-CRF from human CRFR1 expressed in human IMR32 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Bristol-Myers Squibb Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50314012BDBM50314012(N-(cyclobutylmethyl)-2,2,2-trifluoro-N-((8-mesityl...)
Affinity DataKi:  27nMAssay Description:Displacement of [125I]Tyr-o-CRF from human CRFR1 expressed in human IMR32 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Bristol-Myers Squibb Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50314013BDBM50314013(N-(cyclopropylmethyl)-N-((8-mesityl-2-(trifluorome...)
Affinity DataKi:  31nMAssay Description:Displacement of [125I]Tyr-o-CRF from human CRFR1 expressed in human IMR32 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Bristol-Myers Squibb Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50314007BDBM50314007(N-(cyclopropylmethyl)-N-((8-mesityl-2-(trifluorome...)
Affinity DataKi:  32nMAssay Description:Displacement of [125I]Tyr-o-CRF from human CRFR1 expressed in human IMR32 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Bristol-Myers Squibb Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50314015BDBM50314015(2,2,2-trifluoro-N-((8-mesityl-2-(trifluoromethyl)-...)
Affinity DataKi:  38nMAssay Description:Displacement of [125I]Tyr-o-CRF from human CRFR1 expressed in human IMR32 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Bristol-Myers Squibb Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50314016BDBM50314016(N-((8-mesityl-2-(trifluoromethyl)-5,6,7,8-tetrahyd...)
Affinity DataKi:  48nMAssay Description:Displacement of [125I]Tyr-o-CRF from human CRFR1 expressed in human IMR32 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Bristol-Myers Squibb Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50314017BDBM50314017(3,3,3-trifluoro-N-((8-mesityl-2-(trifluoromethyl)-...)
Affinity DataKi:  63nMAssay Description:Displacement of [125I]Tyr-o-CRF from human CRFR1 expressed in human IMR32 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Bristol-Myers Squibb Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50314014BDBM50314014(N-((8-mesityl-2-(trifluoromethyl)-5,6,7,8-tetrahyd...)
Affinity DataKi:  67nMAssay Description:Displacement of [125I]Tyr-o-CRF from human CRFR1 expressed in human IMR32 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Bristol-Myers Squibb Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50314018BDBM50314018(8-mesityl-3-(piperidin-1-ylmethyl)-2-(trifluoromet...)
Affinity DataKi:  245nMAssay Description:Displacement of [125I]Tyr-o-CRF from human CRFR1 expressed in human IMR32 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Bristol-Myers Squibb Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50314019BDBM50314019(3-((5,6-dihydropyridin-1(2H)-yl)methyl)-8-mesityl-...)
Affinity DataKi:  364nMAssay Description:Displacement of [125I]Tyr-o-CRF from human CRFR1 expressed in human IMR32 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Bristol-Myers Squibb Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50314021BDBM50314021(4-((8-mesityl-2-(trifluoromethyl)-5,6,7,8-tetrahyd...)
Affinity DataKi:  441nMAssay Description:Displacement of [125I]Tyr-o-CRF from human CRFR1 expressed in human IMR32 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Bristol-Myers Squibb Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50313996BDBM50313996(N-(cyclopropylmethyl)-8-mesityl-N-propyl-2-(triflu...)
Affinity DataKi:  1.20E+3nMAssay Description:Displacement of [125I]Tyr-o-CRF from human CRFR1 expressed in human IMR32 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Bristol-Myers Squibb Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50314020BDBM50314020(4-((8-mesityl-2-(trifluoromethyl)-5,6,7,8-tetrahyd...)
Affinity DataKi:  1.51E+3nMAssay Description:Displacement of [125I]Tyr-o-CRF from human CRFR1 expressed in human IMR32 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Bristol-Myers Squibb Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50313991BDBM50313991(8-mesityl-2-methyl-N-phenethyl-N-propyl-5,6,7,8-te...)
Affinity DataKi:  1.70E+3nMAssay Description:Displacement of [125I]Tyr-o-CRF from human CRFR1 expressed in human IMR32 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Bristol-Myers Squibb Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50313995BDBM50313995(N-(cyclopropylmethyl)-2-ethyl-8-mesityl-N-propyl-5...)
Affinity DataKi:  2.30E+3nMAssay Description:Displacement of [125I]Tyr-o-CRF from human CRFR1 expressed in human IMR32 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Bristol-Myers Squibb Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50313990BDBM50313990(N-(cyclobutylmethyl)-8-mesityl-2-methyl-N-propyl-5...)
Affinity DataKi:  3.30E+3nMAssay Description:Displacement of [125I]Tyr-o-CRF from human CRFR1 expressed in human IMR32 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Bristol-Myers Squibb Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50313989BDBM50313989(N,N-bis(cyclopropylmethyl)-8-mesityl-2-methyl-5,6,...)
Affinity DataKi:  3.40E+3nMAssay Description:Displacement of [125I]Tyr-o-CRF from human CRFR1 expressed in human IMR32 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Bristol-Myers Squibb Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50314002BDBM50314002(N-(cyclopropylmethyl)-2-ethyl-8-mesityl-7-oxo-N-pr...)
Affinity DataKi: >5.00E+3nMAssay Description:Displacement of [125I]Tyr-o-CRF from human CRFR1 expressed in human IMR32 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Bristol-Myers Squibb Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50314001BDBM50314001(8-mesityl-2-methyl-3-(morpholine-4-carbonyl)-5,6-d...)
Affinity DataKi: >5.00E+3nMAssay Description:Displacement of [125I]Tyr-o-CRF from human CRFR1 expressed in human IMR32 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Bristol-Myers Squibb Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50314000BDBM50314000(3-(4-(2-fluorophenyl)piperazine-1-carbonyl)-8-mesi...)
Affinity DataKi: >5.00E+3nMAssay Description:Displacement of [125I]Tyr-o-CRF from human CRFR1 expressed in human IMR32 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Bristol-Myers Squibb Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50313999BDBM50313999(N-(cyclopropylmethyl)-8-mesityl-2-methyl-7-oxo-N-p...)
Affinity DataKi: >5.00E+3nMAssay Description:Displacement of [125I]Tyr-o-CRF from human CRFR1 expressed in human IMR32 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Bristol-Myers Squibb Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50314006BDBM50314006(N-butyl-N,2-diethyl-8-mesityl-7-oxo-5,6,7,8-tetrah...)
Affinity DataKi: >5.00E+3nMAssay Description:Displacement of [125I]Tyr-o-CRF from human CRFR1 expressed in human IMR32 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Bristol-Myers Squibb Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50314005BDBM50314005(N,N-diallyl-2-ethyl-8-mesityl-7-oxo-5,6,7,8-tetrah...)
Affinity DataKi: >5.00E+3nMAssay Description:Displacement of [125I]Tyr-o-CRF from human CRFR1 expressed in human IMR32 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Bristol-Myers Squibb Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50314004BDBM50314004(2-ethyl-8-mesityl-7-oxo-N,N-dipropyl-5,6,7,8-tetra...)
Affinity DataKi: >5.00E+3nMAssay Description:Displacement of [125I]Tyr-o-CRF from human CRFR1 expressed in human IMR32 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Bristol-Myers Squibb Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50314003BDBM50314003(N-benzyl-N,2-diethyl-8-mesityl-7-oxo-5,6,7,8-tetra...)
Affinity DataKi: >5.00E+3nMAssay Description:Displacement of [125I]Tyr-o-CRF from human CRFR1 expressed in human IMR32 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Bristol-Myers Squibb Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50314022BDBM50314022(8-mesityl-3-((4-methyl-1,4-diazepan-1-yl)methyl)-2...)
Affinity DataKi: >5.00E+3nMAssay Description:Displacement of [125I]Tyr-o-CRF from human CRFR1 expressed in human IMR32 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Bristol-Myers Squibb Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50313994BDBM50313994(N-(cyclopropylmethyl)-8-mesityl-2-methyl-N-propyl-...)
Affinity DataKi: >5.00E+3nMAssay Description:Displacement of [125I]Tyr-o-CRF from human CRFR1 expressed in human IMR32 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Bristol-Myers Squibb Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50313993BDBM50313993(N-allyl-8-mesityl-2-methyl-N-propyl-5,6,7,8-tetrah...)
Affinity DataKi: >5.00E+3nMAssay Description:Displacement of [125I]Tyr-o-CRF from human CRFR1 expressed in human IMR32 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Bristol-Myers Squibb Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50313992BDBM50313992(N-benzyl-8-mesityl-2-methyl-N-propyl-5,6,7,8-tetra...)
Affinity DataKi: >5.00E+3nMAssay Description:Displacement of [125I]Tyr-o-CRF from human CRFR1 expressed in human IMR32 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Bristol-Myers Squibb Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50313998BDBM50313998(N,N-diallyl-8-mesityl-2-methyl-7-oxo-5,6,7,8-tetra...)
Affinity DataKi: >5.00E+3nMAssay Description:Displacement of [125I]Tyr-o-CRF from human CRFR1 expressed in human IMR32 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Bristol-Myers Squibb Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50313997BDBM50313997(8-mesityl-2-methyl-7-oxo-N,N-dipropyl-5,6,7,8-tetr...)
Affinity DataKi: >5.00E+3nMAssay Description:Displacement of [125I]Tyr-o-CRF from human CRFR1 expressed in human IMR32 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed