Compile Data Set for Download or QSAR
Report error Found 65 Enz. Inhib. hit(s) with all data for entry = 50031498
TargetCathepsin S(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50314238BDBM50314238(rac-2-(5-(1-(2-hydroxy-3-(4-(pyridin-2-yl)piperidi...)
Affinity DataIC50: 1nMAssay Description:Inhibition of human recombinant cathepsin S expressed in baculovirus expression sytem after 15 mins by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetCathepsin S(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50314240BDBM50314240(2-(5-(1-(2-hydroxy-3-(4-(pyridin-2-yl)piperidin-1-...)
Affinity DataIC50: 7nMAssay Description:Inhibition of human recombinant cathepsin S expressed in baculovirus expression sytem after 15 mins by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetCathepsin S(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50314239BDBM50314239(rac-2-(5-(1-(2-hydroxy-3-(4-(pyridin-2-yl)piperidi...)
Affinity DataIC50: 7nMAssay Description:Inhibition of human recombinant cathepsin S expressed in baculovirus expression sytem after 15 mins by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetCathepsin S(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50314242BDBM50314242(rac-2-hydroxy-1-(1-(2-hydroxy-3-(4-(pyridin-2-yl)p...)
Affinity DataIC50: 10nMAssay Description:Inhibition of human recombinant cathepsin S expressed in baculovirus expression sytem after 15 mins by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetCathepsin S(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50314241BDBM50314241(2-(5-(1-(2-hydroxy-3-(4-(pyridin-2-yl)piperidin-1-...)
Affinity DataIC50: 10nMAssay Description:Inhibition of human recombinant cathepsin S expressed in baculovirus expression sytem after 15 mins by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetCathepsin S(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50314231BDBM50314231(rac-2-(5-(1-(2-hydroxy-3-(4-(2-methoxyphenyl)piper...)
Affinity DataIC50: 10nMAssay Description:Inhibition of human recombinant cathepsin S expressed in baculovirus expression sytem after 15 mins by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetCathepsin S(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50314246BDBM50314246(rac-2-hydroxy-1-(1-(2-hydroxy-3-(4-(2-methoxypheny...)
Affinity DataIC50: 10nMAssay Description:Inhibition of human recombinant cathepsin S expressed in baculovirus expression sytem after 15 mins by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetCathepsin S(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50314234BDBM50314234(rac-2-(5-(1-(3-(4-(2-fluorophenyl)piperidin-1-yl)-...)
Affinity DataIC50: 10nMAssay Description:Inhibition of human recombinant cathepsin S expressed in baculovirus expression sytem after 15 mins by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetCathepsin S(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50314233BDBM50314233(rac-4-(1-(2-hydroxy-3-(5-(methylsulfonyl)-3-(3-(2-...)
Affinity DataIC50: 10nMAssay Description:Inhibition of human recombinant cathepsin S expressed in baculovirus expression sytem after 15 mins by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetCathepsin S(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50314232BDBM50314232(rac-2-(5-(1-(2-hydroxy-3-(4-(pyridin-2-yl)piperidi...)
Affinity DataIC50: 10nMAssay Description:Inhibition of human recombinant cathepsin S expressed in baculovirus expression sytem after 15 mins by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetCathepsin S(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50314254BDBM50314254(1-(1-(3-(5-(methylsulfonyl)-3-(3-(2-morpholino-2-o...)
Affinity DataIC50: 20nMAssay Description:Inhibition of human recombinant cathepsin S expressed in baculovirus expression sytem after 15 mins by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetCathepsin S(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50314247BDBM50314247(rac-2-(5-(5-acetyl-1-(2-hydroxy-3-(4-(2-methoxyphe...)
Affinity DataIC50: 20nMAssay Description:Inhibition of human recombinant cathepsin S expressed in baculovirus expression sytem after 15 mins by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetCathepsin S(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50314235BDBM50314235(rac-2-(5-(1-(3-(4-(3-methyl-1,2,4-oxadiazol-5-yl)p...)
Affinity DataIC50: 20nMAssay Description:Inhibition of human recombinant cathepsin S expressed in baculovirus expression sytem after 15 mins by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetCathepsin S(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50314240BDBM50314240(2-(5-(1-(2-hydroxy-3-(4-(pyridin-2-yl)piperidin-1-...)
Affinity DataIC50: 30nMAssay Description:Inhibition of cathepsin S in human JY cells assessed as accumulation of invariant chain p10li after 24 hrs by Western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetCathepsin S(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50314239BDBM50314239(rac-2-(5-(1-(2-hydroxy-3-(4-(pyridin-2-yl)piperidi...)
Affinity DataIC50: 30nMAssay Description:Inhibition of cathepsin S in human JY cells assessed as accumulation of invariant chain p10li after 24 hrs by Western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetCathepsin S(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50314236BDBM50314236(rac-2-(5-(5-(methylsulfonyl)-1-(3-(4-(pyrrolidine-...)
Affinity DataIC50: 40nMAssay Description:Inhibition of human recombinant cathepsin S expressed in baculovirus expression sytem after 15 mins by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetCathepsin S(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50314168BDBM50314168(1-(1-(3-(5-(methylsulfonyl)-3-(3-(2-(piperidin-1-y...)
Affinity DataIC50: 40nMAssay Description:Inhibition of cathepsin S in human JY cells assessed as accumulation of invariant chain p10li after 24 hrs by Western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetCathepsin S(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50314244BDBM50314244(rac-2-(5-(1-(2-hydroxy-3-(4-(pyridin-2-yl)piperidi...)
Affinity DataIC50: 60nMAssay Description:Inhibition of human recombinant cathepsin S expressed in baculovirus expression sytem after 15 mins by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetCathepsin S(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50314244BDBM50314244(rac-2-(5-(1-(2-hydroxy-3-(4-(pyridin-2-yl)piperidi...)
Affinity DataIC50: 60nMAssay Description:Inhibition of cathepsin S in human JY cells assessed as accumulation of invariant chain p10li after 24 hrs by Western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetCathepsin S(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50314249BDBM50314249(rac-2-(5-(1-(2-hydroxy-3-(4-(2-methoxyphenyl)piper...)
Affinity DataIC50: 60nMAssay Description:Inhibition of human recombinant cathepsin S expressed in baculovirus expression sytem after 15 mins by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetCathepsin S(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50314252BDBM50314252(1-(1-(3-(5-(methylsulfonyl)-3-(3-(2-oxo-2-(pyrroli...)
Affinity DataIC50: 60nMAssay Description:Inhibition of human recombinant cathepsin S expressed in baculovirus expression sytem after 15 mins by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetCathepsin S(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50314253BDBM50314253(1-(1-(3-(5-(methylsulfonyl)-3-(3-(2-oxo-2-(piperid...)
Affinity DataIC50: 70nMAssay Description:Inhibition of human recombinant cathepsin S expressed in baculovirus expression sytem after 15 mins by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetCathepsin S(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50314250BDBM50314250(rac-2-(5-(5-acetyl-1-(2-hydroxy-3-(4-methylpiperid...)
Affinity DataIC50: 80nMAssay Description:Inhibition of cathepsin S in human JY cells assessed as accumulation of invariant chain p10li after 24 hrs by Western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetCathepsin S(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50314256BDBM50314256(rac-1-(1-(3-(3-(3-(2-(3-hydroxypyrrolidin-1-yl)-2-...)
Affinity DataIC50: 90nMAssay Description:Inhibition of human recombinant cathepsin S expressed in baculovirus expression sytem after 15 mins by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetCathepsin S(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50314255BDBM50314255(1-(1-(3-(3-(3-(2-(2-methylpyrrolidin-1-yl)-2-oxoet...)
Affinity DataIC50: 100nMAssay Description:Inhibition of human recombinant cathepsin S expressed in baculovirus expression sytem after 15 mins by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetCathepsin S(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50314243BDBM50314243(rac-2-(5-(1-(2-hydroxy-3-(4-(pyridin-2-yl)piperidi...)
Affinity DataIC50: 110nMAssay Description:Inhibition of human recombinant cathepsin S expressed in baculovirus expression sytem after 15 mins by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetCathepsin S(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50314229BDBM50314229(1-(1-(3-(3-(3-(2-(4-methylpiperazin-1-yl)-2-oxoeth...)
Affinity DataIC50: 110nMAssay Description:Inhibition of cathepsin S in human JY cells assessed as accumulation of invariant chain p10li after 24 hrs by Western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetCathepsin S(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50314251BDBM50314251(rac-2-(5-(5-acetyl-1-(2-hydroxy-3-(4-(2-hydroxypro...)
Affinity DataIC50: 110nMAssay Description:Inhibition of cathepsin S in human JY cells assessed as accumulation of invariant chain p10li after 24 hrs by Western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetCathepsin S(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50314258BDBM50314258(1-(1-(3-(3-(3-(2-(4-(hydroxymethyl)piperidin-1-yl)...)
Affinity DataIC50: 120nMAssay Description:Inhibition of human recombinant cathepsin S expressed in baculovirus expression sytem after 15 mins by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetCathepsin S(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50314249BDBM50314249(rac-2-(5-(1-(2-hydroxy-3-(4-(2-methoxyphenyl)piper...)
Affinity DataIC50: 120nMAssay Description:Inhibition of cathepsin S in human JY cells assessed as accumulation of invariant chain p10li after 24 hrs by Western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetCathepsin S(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50314181BDBM50314181(rac-N-(2-(5-(1-(2-hydroxy-3-(4-(2-oxopyrrolidin-1-...)
Affinity DataIC50: 130nMAssay Description:Inhibition of human recombinant cathepsin S expressed in baculovirus expression sytem after 15 mins by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetCathepsin S(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50314251BDBM50314251(rac-2-(5-(5-acetyl-1-(2-hydroxy-3-(4-(2-hydroxypro...)
Affinity DataIC50: 150nMAssay Description:Inhibition of human recombinant cathepsin S expressed in baculovirus expression sytem after 15 mins by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetCathepsin S(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50314242BDBM50314242(rac-2-hydroxy-1-(1-(2-hydroxy-3-(4-(pyridin-2-yl)p...)
Affinity DataIC50: 160nMAssay Description:Inhibition of cathepsin S in human JY cells assessed as accumulation of invariant chain p10li after 24 hrs by Western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetCathepsin S(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50314168BDBM50314168(1-(1-(3-(5-(methylsulfonyl)-3-(3-(2-(piperidin-1-y...)
Affinity DataIC50: 170nMAssay Description:Inhibition of human recombinant cathepsin S expressed in baculovirus expression sytem after 15 mins by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetCathepsin S(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50314250BDBM50314250(rac-2-(5-(5-acetyl-1-(2-hydroxy-3-(4-methylpiperid...)
Affinity DataIC50: 180nMAssay Description:Inhibition of human recombinant cathepsin S expressed in baculovirus expression sytem after 15 mins by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetCathepsin S(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50314231BDBM50314231(rac-2-(5-(1-(2-hydroxy-3-(4-(2-methoxyphenyl)piper...)
Affinity DataIC50: 190nMAssay Description:Inhibition of cathepsin S in human JY cells assessed as accumulation of invariant chain p10li after 24 hrs by Western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetCathepsin S(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50314248BDBM50314248(rac-2-(5-(1-(2-hydroxy-3-(4-(2-methoxyphenyl)piper...)
Affinity DataIC50: 190nMAssay Description:Inhibition of human recombinant cathepsin S expressed in baculovirus expression sytem after 15 mins by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetCathepsin S(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50314257BDBM50314257(1-(1-(3-(3-(3-(2-(4-methylpiperidin-1-yl)-2-oxoeth...)
Affinity DataIC50: 210nMAssay Description:Inhibition of human recombinant cathepsin S expressed in baculovirus expression sytem after 15 mins by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetCathepsin S(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50314245BDBM50314245(rac-2-(5-(5-ethyl-1-(2-hydroxy-3-(4-(pyridin-2-yl)...)
Affinity DataIC50: 250nMAssay Description:Inhibition of human recombinant cathepsin S expressed in baculovirus expression sytem after 15 mins by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetCathepsin S(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50314236BDBM50314236(rac-2-(5-(5-(methylsulfonyl)-1-(3-(4-(pyrrolidine-...)
Affinity DataIC50: 280nMAssay Description:Inhibition of cathepsin S in human JY cells assessed as accumulation of invariant chain p10li after 24 hrs by Western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetCathepsin S(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50314237BDBM50314237(rac-2-(5-(1-(2-hydroxy-3-((S)-2-methylpiperidin-1-...)
Affinity DataIC50: 300nMAssay Description:Inhibition of human recombinant cathepsin S expressed in baculovirus expression sytem after 15 mins by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetCathepsin S(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50314258BDBM50314258(1-(1-(3-(3-(3-(2-(4-(hydroxymethyl)piperidin-1-yl)...)
Affinity DataIC50: 340nMAssay Description:Inhibition of cathepsin S in human JY cells assessed as accumulation of invariant chain p10li after 24 hrs by Western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetCathepsin S(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50314230BDBM50314230(N-benzyl-2-(5-(5-(methylsulfonyl)-1-(3-(4-(2-oxopy...)
Affinity DataIC50: 370nMAssay Description:Inhibition of human recombinant cathepsin S expressed in baculovirus expression sytem after 15 mins by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetCathepsin S(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50314232BDBM50314232(rac-2-(5-(1-(2-hydroxy-3-(4-(pyridin-2-yl)piperidi...)
Affinity DataIC50: 380nMAssay Description:Inhibition of cathepsin S in human JY cells assessed as accumulation of invariant chain p10li after 24 hrs by Western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetCathepsin S(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50314254BDBM50314254(1-(1-(3-(5-(methylsulfonyl)-3-(3-(2-morpholino-2-o...)
Affinity DataIC50: 450nMAssay Description:Inhibition of cathepsin S in human JY cells assessed as accumulation of invariant chain p10li after 24 hrs by Western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetCathepsin S(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50314238BDBM50314238(rac-2-(5-(1-(2-hydroxy-3-(4-(pyridin-2-yl)piperidi...)
Affinity DataIC50: 470nMAssay Description:Inhibition of cathepsin S in human JY cells assessed as accumulation of invariant chain p10li after 24 hrs by Western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetCathepsin S(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50314246BDBM50314246(rac-2-hydroxy-1-(1-(2-hydroxy-3-(4-(2-methoxypheny...)
Affinity DataIC50: 480nMAssay Description:Inhibition of cathepsin S in human JY cells assessed as accumulation of invariant chain p10li after 24 hrs by Western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetCathepsin S(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50314256BDBM50314256(rac-1-(1-(3-(3-(3-(2-(3-hydroxypyrrolidin-1-yl)-2-...)
Affinity DataIC50: 520nMAssay Description:Inhibition of cathepsin S in human JY cells assessed as accumulation of invariant chain p10li after 24 hrs by Western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetCathepsin S(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50314260BDBM50314260(N,N-dimethyl-2-(5-(5-(methylsulfonyl)-1-(3-(4-(2-o...)
Affinity DataIC50: 520nMAssay Description:Inhibition of human recombinant cathepsin S expressed in baculovirus expression sytem after 15 mins by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetCathepsin S(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50314229BDBM50314229(1-(1-(3-(3-(3-(2-(4-methylpiperazin-1-yl)-2-oxoeth...)
Affinity DataIC50: 740nMAssay Description:Inhibition of human recombinant cathepsin S expressed in baculovirus expression sytem after 15 mins by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
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