Compile Data Set for Download or QSAR
maximum 50k data
Found 41 Enz. Inhib. hit(s) with all data for entry = 50031500
TargetHistamine H3 receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50314290(3-benzyl-1-(4-bromophenyl)-1-(1-(pyridin-4-ylmethy...)
Affinity DataKi:  2nMAssay Description:Antagonist activity at human recombinant histamine 3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50314288(1-(1-((2-aminopyridin-4-yl)methyl)piperidin-4-yl)-...)
Affinity DataKi:  3nMAssay Description:Antagonist activity at human recombinant histamine 3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50314294(1-(4-bromophenyl)-1-(1-cyclopentylpiperidin-4-yl)-...)
Affinity DataKi:  7nMAssay Description:Antagonist activity at human recombinant histamine 3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50314296(1-(4-chlorophenyl)-1-(1-ethylpiperidin-4-yl)-3-(4-...)
Affinity DataKi:  7nMAssay Description:Antagonist activity at human recombinant histamine 3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50314292(3-benzyl-1-(4-bromophenyl)-1-(1-cyclopentylpiperid...)
Affinity DataKi:  10nMAssay Description:Antagonist activity at human recombinant histamine 3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50314291(3-benzyl-1-(4-bromophenyl)-1-(1-(pyridazin-4-ylmet...)
Affinity DataKi:  10nMAssay Description:Antagonist activity at human recombinant histamine 3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50314293(1-(4-bromophenyl)-1-(1-cyclopentylpiperidin-4-yl)-...)
Affinity DataKi:  14nMAssay Description:Antagonist activity at human recombinant histamine 3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50314311(1-(4-chlorophenyl)-3-(4-fluorobenzyl)-1-(1-(pyridi...)
Affinity DataKi:  16nMAssay Description:Antagonist activity at human recombinant histamine 3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50314295(1-(4-bromophenyl)-3-(3,4-dichlorobenzyl)-1-(1-ethy...)
Affinity DataKi:  23nMAssay Description:Antagonist activity at human recombinant histamine 3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50314313(1-(4-bromophenyl)-1-(1-cyclopentylpiperidin-4-yl)-...)
Affinity DataKi:  36nMAssay Description:Antagonist activity at human recombinant histamine 3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50314297(1-(5-chloropyridin-2-yl)-1-(1-ethylpiperidin-4-yl)...)
Affinity DataKi:  41nMAssay Description:Antagonist activity at human recombinant histamine 3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50314315(1-(4-bromophenyl)-1-(1-cyclopentylpiperidin-4-yl)-...)
Affinity DataKi:  47nMAssay Description:Antagonist activity at human recombinant histamine 3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50314289(1-(4-chlorophenyl)-3-(4-fluorobenzyl)-1-(1-(pyrida...)
Affinity DataKi:  49nMAssay Description:Antagonist activity at human recombinant histamine 3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50314307(1-(4-bromophenyl)-3-(4-fluorobenzyl)-1-(1-(2-hydro...)
Affinity DataKi:  67nMAssay Description:Antagonist activity at human recombinant histamine 3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50314306(1-(4-chlorophenyl)-3-(4-fluorobenzyl)-1-(1-(2-hydr...)
Affinity DataKi:  86nMAssay Description:Antagonist activity at human recombinant histamine 3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50314314(1-(4-bromophenyl)-1-(1-cyclopentylpiperidin-4-yl)-...)
Affinity DataKi:  191nMAssay Description:Antagonist activity at human recombinant histamine 3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50314298(1-(1-ethylpiperidin-4-yl)-3-(4-fluorobenzyl)-1-(4-...)
Affinity DataKi:  447nMAssay Description:Antagonist activity at human recombinant histamine 3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50314300(1-(1-ethylpiperidin-4-yl)-3-(4-fluorobenzyl)-1-(4-...)
Affinity DataKi:  560nMAssay Description:Antagonist activity at human recombinant histamine 3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50314312(1-(4-chlorophenyl)-3-(4-fluorobenzyl)-1-(1-((2-hyd...)
Affinity DataKi:  624nMAssay Description:Antagonist activity at human recombinant histamine 3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50314305(1-(4-chlorophenyl)-3-(4-fluorobenzyl)-1-(1-(methyl...)
Affinity DataKi:  858nMAssay Description:Antagonist activity at human recombinant histamine 3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50314304(1-(4-chlorophenyl)-3-(4-fluorobenzyl)-1-(piperidin...)
Affinity DataKi: >1.00E+3nMAssay Description:Antagonist activity at human recombinant histamine 3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50314303(1-(1-ethylpiperidin-4-yl)-3-(4-fluorobenzyl)-1-(1-...)
Affinity DataKi: >1.00E+3nMAssay Description:Antagonist activity at human recombinant histamine 3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50314309(4-(1-(4-chlorophenyl)-3-(4-fluorobenzyl)ureido)-N-...)
Affinity DataKi: >1.00E+3nMAssay Description:Antagonist activity at human recombinant histamine 3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50314301(1-(4-bromobenzyl)-1-(1-ethylpiperidin-4-yl)-3-(4-f...)
Affinity DataKi: >1.00E+3nMAssay Description:Antagonist activity at human recombinant histamine 3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50314299(1-(1-cyclopentylpiperidin-4-yl)-3-(4-fluorobenzyl)...)
Affinity DataKi: >1.00E+3nMAssay Description:Antagonist activity at human recombinant histamine 3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50314310(1-(4-chlorophenyl)-3-(4-fluorobenzyl)-1-(1-(pyridi...)
Affinity DataKi: >1.00E+3nMAssay Description:Antagonist activity at human recombinant histamine 3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50314302(1-(1-ethylpiperidin-4-yl)-3-(4-fluorobenzyl)-1-(pi...)
Affinity DataKi: >1.00E+3nMAssay Description:Antagonist activity at human recombinant histamine 3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50314308(1-(4-chlorophenyl)-1-(1-(2,3-dihydroxypropyl)piper...)
Affinity DataKi: >1.00E+3nMAssay Description:Antagonist activity at human recombinant histamine 3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50314313(1-(4-bromophenyl)-1-(1-cyclopentylpiperidin-4-yl)-...)
Affinity DataIC50:  61nMAssay Description:Inhibition of human ERG by ion works assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50314292(3-benzyl-1-(4-bromophenyl)-1-(1-cyclopentylpiperid...)
Affinity DataIC50:  178nMAssay Description:Inhibition of human ERG by ion works assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50314293(1-(4-bromophenyl)-1-(1-cyclopentylpiperidin-4-yl)-...)
Affinity DataIC50:  188nMAssay Description:Inhibition of human ERG by ion works assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50314294(1-(4-bromophenyl)-1-(1-cyclopentylpiperidin-4-yl)-...)
Affinity DataIC50:  202nMAssay Description:Inhibition of human ERG by ion works assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50314288(1-(1-((2-aminopyridin-4-yl)methyl)piperidin-4-yl)-...)
Affinity DataIC50:  384nMAssay Description:Inhibition of human ERG by ion works assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50314290(3-benzyl-1-(4-bromophenyl)-1-(1-(pyridin-4-ylmethy...)
Affinity DataIC50:  2.31E+3nMAssay Description:Inhibition of human ERG by ion works assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50314311(1-(4-chlorophenyl)-3-(4-fluorobenzyl)-1-(1-(pyridi...)
Affinity DataIC50:  3.81E+3nMAssay Description:Inhibition of human ERG by ion works assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50314296(1-(4-chlorophenyl)-1-(1-ethylpiperidin-4-yl)-3-(4-...)
Affinity DataIC50:  6.65E+3nMAssay Description:Inhibition of human ERG by ion works assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50314307(1-(4-bromophenyl)-3-(4-fluorobenzyl)-1-(1-(2-hydro...)
Affinity DataIC50:  7.88E+3nMAssay Description:Inhibition of human ERG by ion works assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50314297(1-(5-chloropyridin-2-yl)-1-(1-ethylpiperidin-4-yl)...)
Affinity DataIC50:  9.19E+3nMAssay Description:Inhibition of human ERG by ion works assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50314289(1-(4-chlorophenyl)-3-(4-fluorobenzyl)-1-(1-(pyrida...)
Affinity DataIC50:  1.20E+4nMAssay Description:Inhibition of human ERG by ion works assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50314306(1-(4-chlorophenyl)-3-(4-fluorobenzyl)-1-(1-(2-hydr...)
Affinity DataIC50:  1.27E+4nMAssay Description:Inhibition of human ERG by ion works assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50314291(3-benzyl-1-(4-bromophenyl)-1-(1-(pyridazin-4-ylmet...)
Affinity DataIC50:  1.38E+4nMAssay Description:Inhibition of human ERG by ion works assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed