Compile Data Set for Download or QSAR
Report error Found 12 Enz. Inhib. hit(s) with all data for entry = 50031550
TargetSerine/threonine-protein kinase mTOR(Rat)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50315219(1-(4-(4,6-di(8-oxa-3-azabicyclo[3.2.1]octan-3-yl)-...)
Affinity DataIC50: 0.5nMAssay Description:Inhibition of rat brain mTOR assessed as p70S6K-GST protein phosphorylation after 30 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Rat)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50315047(1-(4-(4,6-di(3-oxa-8-azabicyclo[3.2.1]octan-8-yl)-...)
Affinity DataIC50: 1nMAssay Description:Inhibition of rat brain mTOR assessed as p70S6K-GST protein phosphorylation after 30 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Rat)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50315209(1-(4-(4,6-di(8-oxa-3-azabicyclo[3.2.1]octan-3-yl)-...)
Affinity DataIC50: 1.70nMAssay Description:Inhibition of rat brain mTOR assessed as p70S6K-GST protein phosphorylation after 30 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Rat)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50315212(1-(4-(4-(8-oxa-3-azabicyclo[3.2.1]octan-3-yl)-6-(3...)
Affinity DataIC50: 2nMAssay Description:Inhibition of rat brain mTOR assessed as p70S6K-GST protein phosphorylation after 30 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Rat)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50315216(1-(4-(4,6-di(8-oxa-3-azabicyclo[3.2.1]octan-3-yl)-...)
Affinity DataIC50: 2.5nMAssay Description:Inhibition of rat brain mTOR assessed as p70S6K-GST protein phosphorylation after 30 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Rat)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50315218(1-cyclopropyl-3-(4-(4,6-di(8-oxa-3-azabicyclo[3.2....)
Affinity DataIC50: 2.60nMAssay Description:Inhibition of rat brain mTOR assessed as p70S6K-GST protein phosphorylation after 30 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Rat)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50315217(1-(4-(4,6-di(8-oxa-3-azabicyclo[3.2.1]octan-3-yl)-...)
Affinity DataIC50: 2.80nMAssay Description:Inhibition of rat brain mTOR assessed as p70S6K-GST protein phosphorylation after 30 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Rat)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50315211(1-(4-(4,6-di((1S,4S)-2-oxa-5-azabicyclo[2.2.1]hept...)
Affinity DataIC50: 35nMAssay Description:Inhibition of rat brain mTOR assessed as p70S6K-GST protein phosphorylation after 30 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Rat)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50315214(3,3'-(6-(2-(difluoromethyl)-1H-benzo[d]imidazol-1-...)
Affinity DataIC50: 44nMAssay Description:Inhibition of rat brain mTOR assessed as p70S6K-GST protein phosphorylation after 30 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Rat)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50315213(TCMDC-137004 | 2-(difluoromethyl)-1-(4,6-dimorphol...)
Affinity DataIC50: 45nMAssay Description:Inhibition of rat brain mTOR assessed as p70S6K-GST protein phosphorylation after 30 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Rat)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50315215(3-(4-(2-(difluoromethyl)-1H-benzo[d]imidazol-1-yl)...)
Affinity DataIC50: 60nMAssay Description:Inhibition of rat brain mTOR assessed as p70S6K-GST protein phosphorylation after 30 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Rat)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50315210(1-(4-(4,6-di((1R,4R)-2-oxa-5-azabicyclo[2.2.1]hept...)
Affinity DataIC50: 130nMAssay Description:Inhibition of rat brain mTOR assessed as p70S6K-GST protein phosphorylation after 30 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed