Compile Data Set for Download or QSAR
maximum 50k data
Found 87 Enz. Inhib. hit(s) with all data for entry = 50031568
LigandPNGBDBM50315438(4,6-dihydroxy-2-((5-methoxy-2-(pyridin-3-yl)-1H-in...)
Affinity DataIC50:  1nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50315438(4,6-dihydroxy-2-((5-methoxy-2-(pyridin-3-yl)-1H-in...)
Affinity DataIC50:  1nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50315439(4,6-dihydroxy-2-((5-methoxy-2-phenyl-1H-indol-3-yl...)
Affinity DataIC50:  2nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50315445(4,6-dihydroxy-2-((5-methoxy-2-methyl-1H-indol-3-yl...)
Affinity DataIC50:  3nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50315445(4,6-dihydroxy-2-((5-methoxy-2-methyl-1H-indol-3-yl...)
Affinity DataIC50:  3nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50315460(4,6-dihydroxy-2-((1-(2-(4-(3-hydroxypropyl)piperaz...)
Affinity DataIC50:  4nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50315466(4,6-dihydroxy-2-((5-methoxy-1,2-dimethyl-1H-indol-...)
Affinity DataIC50:  4nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50315461(4,6-dihydroxy-2-((5-methoxy-2-methyl-1-(2-(4-methy...)
Affinity DataIC50:  5nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50315456(2-((1-(3-(dimethylamino)propyl)-5-methoxy-2-methyl...)
Affinity DataIC50:  5nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50315453(4,6-dihydroxy-2-((1-(3-(4-(2-hydroxyethyl)piperazi...)
Affinity DataIC50:  6nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50315460(4,6-dihydroxy-2-((1-(2-(4-(3-hydroxypropyl)piperaz...)
Affinity DataIC50:  7nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50315466(4,6-dihydroxy-2-((5-methoxy-1,2-dimethyl-1H-indol-...)
Affinity DataIC50:  7nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50315455(4,6-dihydroxy-2-((5-methoxy-2-methyl-1-(3-morpholi...)
Affinity DataIC50:  8nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50315463(2-((1-(2-(dimethylamino)ethyl)-5-methoxy-2-methyl-...)
Affinity DataIC50:  9nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50315462(4,6-dihydroxy-2-((5-methoxy-2-methyl-1-(2-morpholi...)
Affinity DataIC50:  9nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50315439(4,6-dihydroxy-2-((5-methoxy-2-phenyl-1H-indol-3-yl...)
Affinity DataIC50:  10nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50315438(4,6-dihydroxy-2-((5-methoxy-2-(pyridin-3-yl)-1H-in...)
Affinity DataIC50:  10nMAssay Description:Inhibition of PI3KgammaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50315461(4,6-dihydroxy-2-((5-methoxy-2-methyl-1-(2-(4-methy...)
Affinity DataIC50:  11nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50315462(4,6-dihydroxy-2-((5-methoxy-2-methyl-1-(2-morpholi...)
Affinity DataIC50:  11nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50315439(4,6-dihydroxy-2-((5-methoxy-2-phenyl-1H-indol-3-yl...)
Affinity DataIC50:  11nMAssay Description:Inhibition of PI3KgammaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50315454(4,6-dihydroxy-2-((5-methoxy-2-methyl-1-(3-(4-methy...)
Affinity DataIC50:  15nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50315455(4,6-dihydroxy-2-((5-methoxy-2-methyl-1-(3-morpholi...)
Affinity DataIC50:  18nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50315463(2-((1-(2-(dimethylamino)ethyl)-5-methoxy-2-methyl-...)
Affinity DataIC50:  18nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50315443(4,6-dihydroxy-2-((2-(pyridin-2-yl)-1H-indol-3-yl)m...)
Affinity DataIC50:  22nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50315445(4,6-dihydroxy-2-((5-methoxy-2-methyl-1H-indol-3-yl...)
Affinity DataIC50:  25nMAssay Description:Inhibition of PI3KgammaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50315449(4,6-dihydroxy-2-((5-methoxy-1H-indol-3-yl)methylen...)
Affinity DataIC50:  30nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50315464(4,6-dihydroxy-2-((1-(2-(4-(3-hydroxypropyl)piperaz...)
Affinity DataIC50:  36nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50315457(4,6-dihydroxy-2-((1-(3-(4-(2-hydroxyethyl)piperazi...)
Affinity DataIC50:  37nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50315459(2-((1-(3-(dimethylamino)propyl)-5-methoxy-1H-indol...)
Affinity DataIC50:  40nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50315458(4,6-dihydroxy-2-((5-methoxy-1-(3-morpholinopropyl)...)
Affinity DataIC50:  42nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50315466(4,6-dihydroxy-2-((5-methoxy-1,2-dimethyl-1H-indol-...)
Affinity DataIC50:  54nMAssay Description:Inhibition of PI3KgammaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50315437(4,6-dihydroxy-2-((5-methoxy-1-methyl-1H-indol-3-yl...)
Affinity DataIC50:  62nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50315455(4,6-dihydroxy-2-((5-methoxy-2-methyl-1-(3-morpholi...)
Affinity DataIC50:  76nMAssay Description:Inhibition of PI3KgammaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50315465(4,6-dihydroxy-2-((1-methyl-2-phenyl-1H-indol-3-yl)...)
Affinity DataIC50:  96nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50315437(4,6-dihydroxy-2-((5-methoxy-1-methyl-1H-indol-3-yl...)
Affinity DataIC50:  106nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50315453(4,6-dihydroxy-2-((1-(3-(4-(2-hydroxyethyl)piperazi...)
Affinity DataIC50:  108nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50315453(4,6-dihydroxy-2-((1-(3-(4-(2-hydroxyethyl)piperazi...)
Affinity DataIC50:  109nMAssay Description:Inhibition of PI3KgammaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50315456(2-((1-(3-(dimethylamino)propyl)-5-methoxy-2-methyl...)
Affinity DataIC50:  118nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50315442(2-((2-(4-fluorophenyl)-1H-indol-3-yl)methylene)-4,...)
Affinity DataIC50:  123nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50315444(4,6-dihydroxy-2-((2-phenyl-1H-indol-3-yl)methylene...)
Affinity DataIC50:  130nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50315454(4,6-dihydroxy-2-((5-methoxy-2-methyl-1-(3-(4-methy...)
Affinity DataIC50:  153nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50315462(4,6-dihydroxy-2-((5-methoxy-2-methyl-1-(2-morpholi...)
Affinity DataIC50:  155nMAssay Description:Inhibition of PI3KgammaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50315446(2-((5-bromo-2-methyl-1H-indol-3-yl)methylene)-4,6-...)
Affinity DataIC50:  179nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50315441(2-((2-(4-chlorophenyl)-1H-indol-3-yl)methylene)-4,...)
Affinity DataIC50:  190nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50315446(2-((5-bromo-2-methyl-1H-indol-3-yl)methylene)-4,6-...)
Affinity DataIC50:  190nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50315464(4,6-dihydroxy-2-((1-(2-(4-(3-hydroxypropyl)piperaz...)
Affinity DataIC50:  215nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50315449(4,6-dihydroxy-2-((5-methoxy-1H-indol-3-yl)methylen...)
Affinity DataIC50:  265nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50315449(4,6-dihydroxy-2-((5-methoxy-1H-indol-3-yl)methylen...)
Affinity DataIC50:  269nMAssay Description:Inhibition of PI3KgammaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50315440(4,6-dihydroxy-2-((2-(naphthalen-2-yl)-1H-indol-3-y...)
Affinity DataIC50:  280nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50315463(2-((1-(2-(dimethylamino)ethyl)-5-methoxy-2-methyl-...)
Affinity DataIC50:  283nMAssay Description:Inhibition of PI3KgammaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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