Compile Data Set for Download or QSAR
maximum 50k data
Found 22 Enz. Inhib. hit(s) with all data for entry = 50031579
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50314051(CHEMBL1089082 | N-(3-(2-(pyridin-4-yl)pyrazolo[1,5...)
Affinity DataIC50:  32nMAssay Description:Inhibition of B-RafMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50315652(CHEMBL1090143 | N-(3-(6-(pyridin-4-yl)thieno[2,3-d...)
Affinity DataIC50:  80nMAssay Description:Inhibition of B-RafMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50315650(CHEMBL1090804 | N-(3-(6-(pyridin-4-yl)thieno[3,2-d...)
Affinity DataIC50:  540nMAssay Description:Inhibition of B-RafMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50315651(CHEMBL1093588 | N-(3-(6-(pyridin-3-yl)thieno[2,3-d...)
Affinity DataIC50:  1.11E+3nMAssay Description:Inhibition of B-RafMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50315654(CHEMBL1091543 | N-(3-(6-cyano-2-(pyridin-4-yl)thie...)
Affinity DataIC50:  5.94E+3nMAssay Description:Inhibition of B-RafMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 4(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50315652(CHEMBL1090143 | N-(3-(6-(pyridin-4-yl)thieno[2,3-d...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CDK4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50315652(CHEMBL1090143 | N-(3-(6-(pyridin-4-yl)thieno[2,3-d...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of AKTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50315652(CHEMBL1090143 | N-(3-(6-(pyridin-4-yl)thieno[2,3-d...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50315652(CHEMBL1090143 | N-(3-(6-(pyridin-4-yl)thieno[2,3-d...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of ITKMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C theta type(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50315652(CHEMBL1090143 | N-(3-(6-(pyridin-4-yl)thieno[2,3-d...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of PKCthetaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50315652(CHEMBL1090143 | N-(3-(6-(pyridin-4-yl)thieno[2,3-d...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of BTKMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50315652(CHEMBL1090143 | N-(3-(6-(pyridin-4-yl)thieno[2,3-d...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of SRCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lyn(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50315652(CHEMBL1090143 | N-(3-(6-(pyridin-4-yl)thieno[2,3-d...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of LYNMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50315652(CHEMBL1090143 | N-(3-(6-(pyridin-4-yl)thieno[2,3-d...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of PDK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50315652(CHEMBL1090143 | N-(3-(6-(pyridin-4-yl)thieno[2,3-d...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of LCKMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50315652(CHEMBL1090143 | N-(3-(6-(pyridin-4-yl)thieno[2,3-d...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50315656(CHEMBL1091522 | N-(3-(5-cyano-2-(pyridin-4-yl)thie...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of B-RafMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50315655(CHEMBL1091544 | N-(3-(5-cyano-2-(pyridin-3-yl)thie...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of B-RafMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50315653(CHEMBL1090144 | N-(3-(6-cyano-2-(pyridin-3-yl)thie...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of B-RafMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50315649(CHEMBL1090803 | N-(3-(6-(pyridin-3-yl)thieno[3,2-d...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of B-RafMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50314052(CHEMBL1091500 | N-(3-(2-(pyridin-3-yl)pyrazolo[1,5...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of B-RafMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50315652(CHEMBL1090143 | N-(3-(6-(pyridin-4-yl)thieno[2,3-d...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of IKK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed