Compile Data Set for Download or QSAR
maximum 50k data
Found 39 Enz. Inhib. hit(s) with all data for entry = 50031590
TargetAurora kinase A(Homo sapiens (Human))
S*Bio

Curated by ChEMBL
LigandPNGBDBM50315839(4-methyl-N-(3-(2-(6-methyl-5-(2-(thiophen-2-yl)ace...)
Affinity DataIC50:  13nMAssay Description:Inhibition of hexahistidine tagged recombinant Aurora A expressed in Hi-5 cells assessed as ATP remaining after 2 hrs by bioluminnescenceMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
S*Bio

Curated by ChEMBL
LigandPNGBDBM50315848(CHEMBL1090568 | N-(6-methyl-3-styryl-1H-indazol-5-...)
Affinity DataIC50:  17nMAssay Description:Inhibition of hexahistidine tagged recombinant Aurora A expressed in Hi-5 cells assessed as ATP remaining after 2 hrs by bioluminnescenceMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
S*Bio

Curated by ChEMBL
LigandPNGBDBM50315850(CHEMBL1091643 | N-(6-methyl-3-styryl-1H-indazol-5-...)
Affinity DataIC50:  19nMAssay Description:Inhibition of hexahistidine tagged recombinant Aurora A expressed in Hi-5 cells assessed as ATP remaining after 2 hrs by bioluminnescenceMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
S*Bio

Curated by ChEMBL
LigandPNGBDBM50315851(2-phenyl-N-(3-styryl-1H-indazol-5-yl)acetamide | C...)
Affinity DataIC50:  22nMAssay Description:Inhibition of hexahistidine tagged recombinant Aurora A expressed in Hi-5 cells assessed as ATP remaining after 2 hrs by bioluminnescenceMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase B(Homo sapiens (Human))
S*Bio

Curated by ChEMBL
LigandPNGBDBM50315837(CHEMBL1091232 | N-(3-(3-((4-methylpiperazin-1-yl)m...)
Affinity DataIC50:  26nMAssay Description:Inhibition of GST tagged recombinant Aurora B expressed in Hi-5 cells after 1 hr by TRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase B(Homo sapiens (Human))
S*Bio

Curated by ChEMBL
LigandPNGBDBM50315832(3-methyl-5-(4-methyl-3-(3-((4-methylpiperazin-1-yl...)
Affinity DataIC50:  31nMAssay Description:Inhibition of GST tagged recombinant Aurora B expressed in Hi-5 cells after 1 hr by TRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase B(Homo sapiens (Human))
S*Bio

Curated by ChEMBL
LigandPNGBDBM50315834(1-phenyl-N-(3-styryl-1H-indazol-5-yl)methanesulfon...)
Affinity DataIC50:  31nMAssay Description:Inhibition of GST tagged recombinant Aurora B expressed in Hi-5 cells after 1 hr by TRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
S*Bio

Curated by ChEMBL
LigandPNGBDBM50315834(1-phenyl-N-(3-styryl-1H-indazol-5-yl)methanesulfon...)
Affinity DataIC50:  35nMAssay Description:Inhibition of hexahistidine tagged recombinant Aurora A expressed in Hi-5 cells assessed as ATP remaining after 2 hrs by bioluminnescenceMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
S*Bio

Curated by ChEMBL
LigandPNGBDBM50315837(CHEMBL1091232 | N-(3-(3-((4-methylpiperazin-1-yl)m...)
Affinity DataIC50:  35nMAssay Description:Inhibition of hexahistidine tagged recombinant Aurora A expressed in Hi-5 cells assessed as ATP remaining after 2 hrs by bioluminnescenceMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
S*Bio

Curated by ChEMBL
LigandPNGBDBM50315835(2-(2,5-dimethoxyphenyl)-N-(6-methyl-3-styryl-1H-in...)
Affinity DataIC50:  42nMAssay Description:Inhibition of hexahistidine tagged recombinant Aurora A expressed in Hi-5 cells assessed as ATP remaining after 2 hrs by bioluminnescenceMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase B(Homo sapiens (Human))
S*Bio

Curated by ChEMBL
LigandPNGBDBM50315846(5-(pyridin-4-yl)-6-(pyrrolidin-1-yl)-3-styryl-1H-i...)
Affinity DataIC50:  46nMAssay Description:Inhibition of GST tagged recombinant Aurora B expressed in Hi-5 cells after 1 hr by TRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase B(Homo sapiens (Human))
S*Bio

Curated by ChEMBL
LigandPNGBDBM50315839(4-methyl-N-(3-(2-(6-methyl-5-(2-(thiophen-2-yl)ace...)
Affinity DataIC50:  46nMAssay Description:Inhibition of GST tagged recombinant Aurora B expressed in Hi-5 cells after 1 hr by TRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase B(Homo sapiens (Human))
S*Bio

Curated by ChEMBL
LigandPNGBDBM50315848(CHEMBL1090568 | N-(6-methyl-3-styryl-1H-indazol-5-...)
Affinity DataIC50:  47nMAssay Description:Inhibition of GST tagged recombinant Aurora B expressed in Hi-5 cells after 1 hr by TRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase B(Homo sapiens (Human))
S*Bio

Curated by ChEMBL
LigandPNGBDBM50315833(4-methyl-3-(3-((4-methylpiperazin-1-yl)methyl)styr...)
Affinity DataIC50:  59nMAssay Description:Inhibition of GST tagged recombinant Aurora B expressed in Hi-5 cells after 1 hr by TRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase B(Homo sapiens (Human))
S*Bio

Curated by ChEMBL
LigandPNGBDBM50315841(4-methyl-N-(3-(2-(5-(methylsulfonamido)-6-(pyrroli...)
Affinity DataIC50:  62nMAssay Description:Inhibition of GST tagged recombinant Aurora B expressed in Hi-5 cells after 1 hr by TRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
S*Bio

Curated by ChEMBL
LigandPNGBDBM50315838(CHEMBL1091231 | N-(6-methyl-3-(3-((4-methylpiperaz...)
Affinity DataIC50:  79nMAssay Description:Inhibition of hexahistidine tagged recombinant Aurora A expressed in Hi-5 cells assessed as ATP remaining after 2 hrs by bioluminnescenceMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase B(Homo sapiens (Human))
S*Bio

Curated by ChEMBL
LigandPNGBDBM50315842(6-(pyrrolidin-1-yl)-3-styryl-1H-indazol-5-amine | ...)
Affinity DataIC50:  81nMAssay Description:Inhibition of GST tagged recombinant Aurora B expressed in Hi-5 cells after 1 hr by TRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
S*Bio

Curated by ChEMBL
LigandPNGBDBM50315840(CHEMBL1090237 | N-(6-(pyrrolidin-1-yl)-3-styryl-1H...)
Affinity DataIC50:  91nMAssay Description:Inhibition of hexahistidine tagged recombinant Aurora A expressed in Hi-5 cells assessed as ATP remaining after 2 hrs by bioluminnescenceMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase B(Homo sapiens (Human))
S*Bio

Curated by ChEMBL
LigandPNGBDBM50315836(CHEMBL1091233 | N-(4-methyl-3-(3-((4-methylpiperaz...)
Affinity DataIC50:  99nMAssay Description:Inhibition of GST tagged recombinant Aurora B expressed in Hi-5 cells after 1 hr by TRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase B(Homo sapiens (Human))
S*Bio

Curated by ChEMBL
LigandPNGBDBM50315847(CHEMBL1093877 | N-(6-methyl-3-(phenylethynyl)-1H-i...)
Affinity DataIC50:  110nMAssay Description:Inhibition of GST tagged recombinant Aurora B expressed in Hi-5 cells after 1 hr by TRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase B(Homo sapiens (Human))
S*Bio

Curated by ChEMBL
LigandPNGBDBM50315843(5-nitro-6-(pyrrolidin-1-yl)-3-styryl-1H-indazole |...)
Affinity DataIC50:  110nMAssay Description:Inhibition of GST tagged recombinant Aurora B expressed in Hi-5 cells after 1 hr by TRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase B(Homo sapiens (Human))
S*Bio

Curated by ChEMBL
LigandPNGBDBM50315840(CHEMBL1090237 | N-(6-(pyrrolidin-1-yl)-3-styryl-1H...)
Affinity DataIC50:  110nMAssay Description:Inhibition of GST tagged recombinant Aurora B expressed in Hi-5 cells after 1 hr by TRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase B(Homo sapiens (Human))
S*Bio

Curated by ChEMBL
LigandPNGBDBM50315838(CHEMBL1091231 | N-(6-methyl-3-(3-((4-methylpiperaz...)
Affinity DataIC50:  130nMAssay Description:Inhibition of GST tagged recombinant Aurora B expressed in Hi-5 cells after 1 hr by TRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase B(Homo sapiens (Human))
S*Bio

Curated by ChEMBL
LigandPNGBDBM50315844(CHEMBL1093879 | N-(pyridin-2-ylmethyl)-6-(pyrrolid...)
Affinity DataIC50:  130nMAssay Description:Inhibition of GST tagged recombinant Aurora B expressed in Hi-5 cells after 1 hr by TRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
S*Bio

Curated by ChEMBL
LigandPNGBDBM50315841(4-methyl-N-(3-(2-(5-(methylsulfonamido)-6-(pyrroli...)
Affinity DataIC50:  140nMAssay Description:Inhibition of hexahistidine tagged recombinant Aurora A expressed in Hi-5 cells assessed as ATP remaining after 2 hrs by bioluminnescenceMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
S*Bio

Curated by ChEMBL
LigandPNGBDBM50315846(5-(pyridin-4-yl)-6-(pyrrolidin-1-yl)-3-styryl-1H-i...)
Affinity DataIC50:  160nMAssay Description:Inhibition of hexahistidine tagged recombinant Aurora A expressed in Hi-5 cells assessed as ATP remaining after 2 hrs by bioluminnescenceMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase B(Homo sapiens (Human))
S*Bio

Curated by ChEMBL
LigandPNGBDBM50315835(2-(2,5-dimethoxyphenyl)-N-(6-methyl-3-styryl-1H-in...)
Affinity DataIC50:  180nMAssay Description:Inhibition of GST tagged recombinant Aurora B expressed in Hi-5 cells after 1 hr by TRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
S*Bio

Curated by ChEMBL
LigandPNGBDBM50315842(6-(pyrrolidin-1-yl)-3-styryl-1H-indazol-5-amine | ...)
Affinity DataIC50:  200nMAssay Description:Inhibition of hexahistidine tagged recombinant Aurora A expressed in Hi-5 cells assessed as ATP remaining after 2 hrs by bioluminnescenceMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
S*Bio

Curated by ChEMBL
LigandPNGBDBM50315843(5-nitro-6-(pyrrolidin-1-yl)-3-styryl-1H-indazole |...)
Affinity DataIC50:  240nMAssay Description:Inhibition of hexahistidine tagged recombinant Aurora A expressed in Hi-5 cells assessed as ATP remaining after 2 hrs by bioluminnescenceMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
S*Bio

Curated by ChEMBL
LigandPNGBDBM50315847(CHEMBL1093877 | N-(6-methyl-3-(phenylethynyl)-1H-i...)
Affinity DataIC50:  240nMAssay Description:Inhibition of hexahistidine tagged recombinant Aurora A expressed in Hi-5 cells assessed as ATP remaining after 2 hrs by bioluminnescenceMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
S*Bio

Curated by ChEMBL
LigandPNGBDBM50315833(4-methyl-3-(3-((4-methylpiperazin-1-yl)methyl)styr...)
Affinity DataIC50:  280nMAssay Description:Inhibition of hexahistidine tagged recombinant Aurora A expressed in Hi-5 cells assessed as ATP remaining after 2 hrs by bioluminnescenceMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
S*Bio

Curated by ChEMBL
LigandPNGBDBM50315832(3-methyl-5-(4-methyl-3-(3-((4-methylpiperazin-1-yl...)
Affinity DataIC50:  350nMAssay Description:Inhibition of hexahistidine tagged recombinant Aurora A expressed in Hi-5 cells assessed as ATP remaining after 2 hrs by bioluminnescenceMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
S*Bio

Curated by ChEMBL
LigandPNGBDBM50315844(CHEMBL1093879 | N-(pyridin-2-ylmethyl)-6-(pyrrolid...)
Affinity DataIC50:  620nMAssay Description:Inhibition of hexahistidine tagged recombinant Aurora A expressed in Hi-5 cells assessed as ATP remaining after 2 hrs by bioluminnescenceMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
S*Bio

Curated by ChEMBL
LigandPNGBDBM50315849(2-phenyl-N-(3-(2-phenylcyclopropyl)-1H-indazol-5-y...)
Affinity DataIC50:  640nMAssay Description:Inhibition of hexahistidine tagged recombinant Aurora A expressed in Hi-5 cells assessed as ATP remaining after 2 hrs by bioluminnescenceMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase B(Homo sapiens (Human))
S*Bio

Curated by ChEMBL
LigandPNGBDBM50315845(6-(4-methylpiperazin-1-yl)-N-(pyridin-2-ylmethyl)-...)
Affinity DataIC50:  810nMAssay Description:Inhibition of GST tagged recombinant Aurora B expressed in Hi-5 cells after 1 hr by TRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase B(Homo sapiens (Human))
S*Bio

Curated by ChEMBL
LigandPNGBDBM50315849(2-phenyl-N-(3-(2-phenylcyclopropyl)-1H-indazol-5-y...)
Affinity DataIC50:  1.64E+3nMAssay Description:Inhibition of GST tagged recombinant Aurora B expressed in Hi-5 cells after 1 hr by TRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
S*Bio

Curated by ChEMBL
LigandPNGBDBM50315852(CHEMBL1090910 | N-(3-phenethyl-1H-indazol-5-yl)-2-...)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibition of hexahistidine tagged recombinant Aurora A expressed in Hi-5 cells assessed as ATP remaining after 2 hrs by bioluminnescenceMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
S*Bio

Curated by ChEMBL
LigandPNGBDBM50315836(CHEMBL1091233 | N-(4-methyl-3-(3-((4-methylpiperaz...)
Affinity DataIC50:  1.90E+3nMAssay Description:Inhibition of hexahistidine tagged recombinant Aurora A expressed in Hi-5 cells assessed as ATP remaining after 2 hrs by bioluminnescenceMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
S*Bio

Curated by ChEMBL
LigandPNGBDBM50315845(6-(4-methylpiperazin-1-yl)-N-(pyridin-2-ylmethyl)-...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of hexahistidine tagged recombinant Aurora A expressed in Hi-5 cells assessed as ATP remaining after 2 hrs by bioluminnescenceMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed