Compile Data Set for Download or QSAR
Report error Found 34 Enz. Inhib. hit(s) with all data for entry = 50041799
TargetOxysterols receptor LXR-alpha(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50415825(CHEMBL1091034)
Affinity DataEC50:  10nMAssay Description:Agonist activity at LXRalpha ligand binding domain-mediated transcriptional activity in african green monkey CV1 cells co-transfected with Gal4-SRC1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetOxysterols receptor LXR-beta(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50415825(CHEMBL1091034)
Affinity DataEC50:  3.20nMAssay Description:Agonist activity at LXRbeta ligand binding domain-mediated transcriptional activity in african green monkey CV1 cells co-transfected with Gal4-SRC1 b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetOxysterols receptor LXR-beta(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM19992(2-{3-[3-({[2-chloro-3-(trifluoromethyl)phenyl]meth...)
Affinity DataEC50:  501nMAssay Description:Agonist activity at LXRbeta ligand binding domain-mediated transcriptional activity in african green monkey CV1 cells co-transfected with Gal4-SRC1 b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetOxysterols receptor LXR-beta(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50415819(CHEMBL1091976)
Affinity DataEC50:  3.20nMAssay Description:Agonist activity at LXRbeta ligand binding domain-mediated transcriptional activity in african green monkey CV1 cells co-transfected with Gal4-SRC1 b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetOxysterols receptor LXR-beta(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50415821(CHEMBL1093554)
Affinity DataEC50:  1nMAssay Description:Agonist activity at LXRbeta ligand binding domain-mediated transcriptional activity in african green monkey CV1 cells co-transfected with Gal4-SRC1 b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetOxysterols receptor LXR-beta(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50415817(CHEMBL1093828)
Affinity DataEC50:  100nMAssay Description:Agonist activity at LXRbeta ligand binding domain-mediated transcriptional activity in african green monkey CV1 cells co-transfected with Gal4-SRC1 b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetOxysterols receptor LXR-beta(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50415820(CHEMBL1093840)
Affinity DataEC50:  20nMAssay Description:Agonist activity at LXRbeta ligand binding domain-mediated transcriptional activity in african green monkey CV1 cells co-transfected with Gal4-SRC1 b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetOxysterols receptor LXR-beta(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50415818(CHEMBL1093523)
Affinity DataEC50:  16nMAssay Description:Agonist activity at LXRbeta ligand binding domain-mediated transcriptional activity in african green monkey CV1 cells co-transfected with Gal4-SRC1 b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetOxysterols receptor LXR-alpha(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM19992(2-{3-[3-({[2-chloro-3-(trifluoromethyl)phenyl]meth...)
Affinity DataEC50:  794nMAssay Description:Agonist activity at LXRalpha ligand binding domain-mediated transcriptional activity in african green monkey CV1 cells co-transfected with Gal4-SRC1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetOxysterols receptor LXR-alpha(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM19993(CHEMBL62136 | [3H]T0901317 | T 0901317 | N-[4-(1,1...)
Affinity DataEC50:  63nMAssay Description:Agonist activity at LXRalpha ligand binding domain-mediated transcriptional activity in african green monkey CV1 cells co-transfected with Gal4-SRC1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetOxysterols receptor LXR-alpha(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50415821(CHEMBL1093554)
Affinity DataEC50:  6.30nMAssay Description:Agonist activity at LXRalpha ligand binding domain-mediated transcriptional activity in african green monkey CV1 cells co-transfected with Gal4-SRC1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetOxysterols receptor LXR-alpha(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50415820(CHEMBL1093840)
Affinity DataEC50:  100nMAssay Description:Agonist activity at LXRalpha ligand binding domain-mediated transcriptional activity in african green monkey CV1 cells co-transfected with Gal4-SRC1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetOxysterols receptor LXR-alpha(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50415819(CHEMBL1091976)
Affinity DataEC50:  13nMAssay Description:Agonist activity at LXRalpha ligand binding domain-mediated transcriptional activity in african green monkey CV1 cells co-transfected with Gal4-SRC1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetOxysterols receptor LXR-alpha(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50415818(CHEMBL1093523)
Affinity DataEC50:  79nMAssay Description:Agonist activity at LXRalpha ligand binding domain-mediated transcriptional activity in african green monkey CV1 cells co-transfected with Gal4-SRC1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetOxysterols receptor LXR-beta(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM19993(CHEMBL62136 | [3H]T0901317 | T 0901317 | N-[4-(1,1...)
Affinity DataEC50:  100nMAssay Description:Agonist activity at LXRbeta ligand binding domain-mediated transcriptional activity in african green monkey CV1 cells co-transfected with Gal4-SRC1 b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetOxysterols receptor LXR-alpha(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50415817(CHEMBL1093828)
Affinity DataEC50:  126nMAssay Description:Agonist activity at LXRalpha ligand binding domain-mediated transcriptional activity in african green monkey CV1 cells co-transfected with Gal4-SRC1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetOxysterols receptor LXR-beta(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50415815(CHEMBL1092952)
Affinity DataEC50:  79nMAssay Description:Agonist activity at LXRbeta ligand binding domain-mediated transcriptional activity in african green monkey CV1 cells co-transfected with Gal4-SRC1 b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetOxysterols receptor LXR-alpha(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50415815(CHEMBL1092952)
Affinity DataEC50:  79nMAssay Description:Agonist activity at LXRalpha ligand binding domain-mediated transcriptional activity in african green monkey CV1 cells co-transfected with Gal4-SRC1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetOxysterols receptor LXR-beta(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50415825(CHEMBL1091034)
Affinity DataIC50: 4nMAssay Description:Displacement of [N-methyl-3H]T1317 from human biotinylated LXRbeta LBD after 3 hrs by LEAD seeker binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetOxysterols receptor LXR-beta(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50415821(CHEMBL1093554)
Affinity DataIC50: 5nMAssay Description:Displacement of [N-methyl-3H]T1317 from human biotinylated LXRbeta LBD after 3 hrs by LEAD seeker binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetOxysterols receptor LXR-beta(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50415820(CHEMBL1093840)
Affinity DataIC50: 6.30nMAssay Description:Displacement of [N-methyl-3H]T1317 from human biotinylated LXRbeta LBD after 3 hrs by LEAD seeker binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetOxysterols receptor LXR-beta(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM19992(2-{3-[3-({[2-chloro-3-(trifluoromethyl)phenyl]meth...)
Affinity DataIC50: 7.90nMAssay Description:Displacement of [N-methyl-3H]T1317 from human biotinylated LXRbeta LBD after 3 hrs by LEAD seeker binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetOxysterols receptor LXR-beta(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50415815(CHEMBL1092952)
Affinity DataIC50: 10nMAssay Description:Displacement of [N-methyl-3H]T1317 from human biotinylated LXRbeta LBD after 3 hrs by LEAD seeker binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetOxysterols receptor LXR-beta(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50415819(CHEMBL1091976)
Affinity DataIC50: 13nMAssay Description:Displacement of [N-methyl-3H]T1317 from human biotinylated LXRbeta LBD after 3 hrs by LEAD seeker binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetOxysterols receptor LXR-beta(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50415818(CHEMBL1093523)
Affinity DataIC50: 16nMAssay Description:Displacement of [N-methyl-3H]T1317 from human biotinylated LXRbeta LBD after 3 hrs by LEAD seeker binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetOxysterols receptor LXR-beta(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM19993(CHEMBL62136 | [3H]T0901317 | T 0901317 | N-[4-(1,1...)
Affinity DataIC50: 20nMAssay Description:Displacement of [N-methyl-3H]T1317 from human biotinylated LXRbeta LBD after 3 hrs by LEAD seeker binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetOxysterols receptor LXR-beta(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50415816(GSK-2033 | CHEMBL1093266)
Affinity DataIC50: 32nMAssay Description:Displacement of [N-methyl-3H]T1317 from human biotinylated LXRbeta LBD after 3 hrs by LEAD seeker binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetOxysterols receptor LXR-beta(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM19992(2-{3-[3-({[2-chloro-3-(trifluoromethyl)phenyl]meth...)
Affinity DataIC50: 40nMAssay Description:Antagonist activity at LXRbeta ligand binding domain assessed as inhibition of T1317-induced transcriptional activity in african green monkey CV1 cel...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetOxysterols receptor LXR-beta(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50415817(CHEMBL1093828)
Affinity DataIC50: 79nMAssay Description:Displacement of [N-methyl-3H]T1317 from human biotinylated LXRbeta LBD after 3 hrs by LEAD seeker binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetOxysterols receptor LXR-alpha(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM19992(2-{3-[3-({[2-chloro-3-(trifluoromethyl)phenyl]meth...)
Affinity DataIC50: 100nMAssay Description:Antagonist activity at LXRalpha ligand binding domain assessed as inhibition of T1317-induced transcriptional activity in african green monkey CV1 ce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetOxysterols receptor LXR-beta(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50415826(CHEMBL1090238)
Affinity DataIC50: 398nMAssay Description:Displacement of [N-methyl-3H]T1317 from human biotinylated LXRbeta LBD after 3 hrs by LEAD seeker binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetOxysterols receptor LXR-beta(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50415824(CHEMBL1090569)
Affinity DataIC50: 3.16E+3nMAssay Description:Displacement of [N-methyl-3H]T1317 from human biotinylated LXRbeta LBD after 3 hrs by LEAD seeker binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetOxysterols receptor LXR-beta(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50415822(CHEMBL1091958)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [N-methyl-3H]T1317 from human biotinylated LXRbeta LBD after 3 hrs by LEAD seeker binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetOxysterols receptor LXR-beta(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50415823(CHEMBL1090570)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [N-methyl-3H]T1317 from human biotinylated LXRbeta LBD after 3 hrs by LEAD seeker binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed