Compile Data Set for Download or QSAR
maximum 50k data
Found 67 Enz. Inhib. hit(s) with all data for entry = 50039144
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50317405(5-(Aminosulfonyl)-2-[(3,4-difluorophenyl)thio]-N-(...)
Affinity DataIC50:  2.19nMAssay Description:Inhibition of carbonic anhydrase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50317417(5-(Aminosulfonyl)-N-ethyl-3-fluoro-2-(isobutylthio...)
Affinity DataIC50:  2.79nMAssay Description:Inhibition of carbonic anhydrase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50317416(5-(Aminosulfonyl)-N-ethyl-3-fluoro-2-(isopropylthi...)
Affinity DataIC50:  3.77nMAssay Description:Inhibition of carbonic anhydrase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50317418(6-[(2,3,5,6-Tetrafluorophenyl)thio]pyridine-3-sulf...)
Affinity DataIC50:  8.29nMAssay Description:Inhibition of carbonic anhydrase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50317389(5-(Aminosulfonyl)-N-benzyl-2-(benzylthio)benzamide...)
Affinity DataIC50:  10.1nMAssay Description:Inhibition of carbonic anhydrase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50317407(5-(Aminosulfonyl)-N-(3-methoxypropyl)-2-[(2,3,5,6-...)
Affinity DataIC50:  10.6nMAssay Description:Inhibition of carbonic anhydrase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50317411(5-(Aminosulfonyl)-N-[2-(4-methoxyphenyl)ethyl]-2-[...)
Affinity DataIC50:  11.5nMAssay Description:Inhibition of carbonic anhydrase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50317386(5-(Aminosulfonyl)-N-benzyl-2-(phenylthio)benzamide...)
Affinity DataIC50:  12.3nMAssay Description:Inhibition of carbonic anhydrase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50317395(5-(Aminosulfonyl)-2-(cyclopentylthio)-N-ethylbenza...)
Affinity DataIC50:  16.5nMAssay Description:Inhibition of carbonic anhydrase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50317409(5-(Aminosulfonyl)-N-(2-pyridin-2-ylethyl)-2-[(2,3,...)
Affinity DataIC50:  18.4nMAssay Description:Inhibition of carbonic anhydrase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50317404(5-(Aminosulfonyl)-N-ethyl-2-[(3-fluorophenyl)thio]...)
Affinity DataIC50:  19.9nMAssay Description:Inhibition of carbonic anhydrase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50317397(5-(Aminosulfonyl)-N-ethyl-2-(phenylthio)nicotinami...)
Affinity DataIC50:  20nMAssay Description:Inhibition of carbonic anhydrase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50317393(5-(Aminosulfonyl)-N-(2-methoxyethyl)-2-[(2-phenyle...)
Affinity DataIC50:  20.2nMAssay Description:Inhibition of carbonic anhydrase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 4(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50317409(5-(Aminosulfonyl)-N-(2-pyridin-2-ylethyl)-2-[(2,3,...)
Affinity DataIC50:  20.9nMAssay Description:Inhibition of carbonic anhydrase 4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50317387(5-(Aminosulfonyl)-N-ethyl-2-(phenylthio)benzamide ...)
Affinity DataIC50:  21.3nMAssay Description:Inhibition of carbonic anhydrase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50317394(5-(Aminosulfonyl)-N-isobutyl-2-(isopropylthio)benz...)
Affinity DataIC50:  21.5nMAssay Description:Inhibition of carbonic anhydrase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 4(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50317411(5-(Aminosulfonyl)-N-[2-(4-methoxyphenyl)ethyl]-2-[...)
Affinity DataIC50:  23nMAssay Description:Inhibition of carbonic anhydrase 4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 4(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50317407(5-(Aminosulfonyl)-N-(3-methoxypropyl)-2-[(2,3,5,6-...)
Affinity DataIC50:  23nMAssay Description:Inhibition of carbonic anhydrase 4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 4(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50317403(5-(Aminosulfonyl)-N-(pyridin-2-ylmethyl)-2-[(2,3,5...)
Affinity DataIC50:  23nMAssay Description:Inhibition of carbonic anhydrase 4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50317403(5-(Aminosulfonyl)-N-(pyridin-2-ylmethyl)-2-[(2,3,5...)
Affinity DataIC50:  23.2nMAssay Description:Inhibition of carbonic anhydrase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50317406(5-(Aminosulfonyl)-N-(3-methoxypropyl)-2-[(3-fluoro...)
Affinity DataIC50:  25.8nMAssay Description:Inhibition of carbonic anhydrase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50317402(5-(Aminosulfonyl)-N-(2-phenylethyl)-2-(phenylthio)...)
Affinity DataIC50:  26.6nMAssay Description:Inhibition of carbonic anhydrase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50317401(5-(Aminosulfonyl)-2-(phenylthio)-N-propylnicotinam...)
Affinity DataIC50:  26.7nMAssay Description:Inhibition of carbonic anhydrase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 4(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50317410(CHEMBL1099151 | N-(3-Aminopropyl)-5-(aminosulfonyl...)
Affinity DataIC50:  33.1nMAssay Description:Inhibition of carbonic anhydrase 4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50317408(5-(Aminosulfonyl)-2-[(3,4-difluorophenyl)thio]-N-(...)
Affinity DataIC50:  34.6nMAssay Description:Inhibition of carbonic anhydrase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50317388(5-(Aminosulfonyl)-N-benzyl-2-phenoxybenzamide | CH...)
Affinity DataIC50:  35.9nMAssay Description:Inhibition of carbonic anhydrase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 4(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM10884((2S,4S)-4-(ethylamino)-2-methyl-1,1-dioxo-2H,3H,4H...)
Affinity DataIC50:  43nMAssay Description:Inhibition of carbonic anhydrase 4More data for this Ligand-Target Pair
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50317410(CHEMBL1099151 | N-(3-Aminopropyl)-5-(aminosulfonyl...)
Affinity DataIC50:  45.9nMAssay Description:Inhibition of carbonic anhydrase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 4(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50317405(5-(Aminosulfonyl)-2-[(3,4-difluorophenyl)thio]-N-(...)
Affinity DataIC50:  46.8nMAssay Description:Inhibition of carbonic anhydrase 4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50317400(5-(Aminosulfonyl)-N-(3-methoxypropyl)-2-(phenylthi...)
Affinity DataIC50:  48nMAssay Description:Inhibition of carbonic anhydrase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50317413(6-[(3,4-Difluorophenyl)thio]-5-{[(4-methoxybenzyl)...)
Affinity DataIC50:  52.8nMAssay Description:Inhibition of carbonic anhydrase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50317399(5-(Aminosulfonyl)-N-(2-methoxyethyl)-2-(phenylthio...)
Affinity DataIC50:  57.1nMAssay Description:Inhibition of carbonic anhydrase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 4(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50317402(5-(Aminosulfonyl)-N-(2-phenylethyl)-2-(phenylthio)...)
Affinity DataIC50:  64nMAssay Description:Inhibition of carbonic anhydrase 4More data for this Ligand-Target Pair
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50317392(5-(Aminosulfonyl)-2-(phenylthio)-N-(pyridin-2-ylme...)
Affinity DataIC50:  67.6nMAssay Description:Inhibition of carbonic anhydrase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50317412(6-[(3,4-Difluorophenyl)thio]-5-(hydroxymethyl)-pyr...)
Affinity DataIC50:  79.3nMAssay Description:Inhibition of carbonic anhydrase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50317391(5-(Aminosulfonyl)-N-(pyridin-2-ylmethyl)-2-(pyridi...)
Affinity DataIC50:  84.1nMAssay Description:Inhibition of carbonic anhydrase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50317390(5-(Aminosulfonyl)-2-{[2-(hydroxymethyl)phenyl]thio...)
Affinity DataIC50:  106nMAssay Description:Inhibition of carbonic anhydrase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 4(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50317406(5-(Aminosulfonyl)-N-(3-methoxypropyl)-2-[(3-fluoro...)
Affinity DataIC50:  118nMAssay Description:Inhibition of carbonic anhydrase 4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 4(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50317404(5-(Aminosulfonyl)-N-ethyl-2-[(3-fluorophenyl)thio]...)
Affinity DataIC50:  126nMAssay Description:Inhibition of carbonic anhydrase 4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 4(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50317408(5-(Aminosulfonyl)-2-[(3,4-difluorophenyl)thio]-N-(...)
Affinity DataIC50:  139nMAssay Description:Inhibition of carbonic anhydrase 4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 4(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50317418(6-[(2,3,5,6-Tetrafluorophenyl)thio]pyridine-3-sulf...)
Affinity DataIC50:  188nMAssay Description:Inhibition of carbonic anhydrase 4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 4(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50317401(5-(Aminosulfonyl)-2-(phenylthio)-N-propylnicotinam...)
Affinity DataIC50:  229nMAssay Description:Inhibition of carbonic anhydrase 4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 4(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50317386(5-(Aminosulfonyl)-N-benzyl-2-(phenylthio)benzamide...)
Affinity DataIC50:  241nMAssay Description:Inhibition of carbonic anhydrase 4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 4(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50317400(5-(Aminosulfonyl)-N-(3-methoxypropyl)-2-(phenylthi...)
Affinity DataIC50:  246nMAssay Description:Inhibition of carbonic anhydrase 4More data for this Ligand-Target Pair
TargetCarbonic anhydrase 4(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50317397(5-(Aminosulfonyl)-N-ethyl-2-(phenylthio)nicotinami...)
Affinity DataIC50:  283nMAssay Description:Inhibition of carbonic anhydrase 4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50317414(6-[(3,4-Difluorophenyl)thio]-5-[(ethylamino)methyl...)
Affinity DataIC50:  321nMAssay Description:Inhibition of carbonic anhydrase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 4(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50317399(5-(Aminosulfonyl)-N-(2-methoxyethyl)-2-(phenylthio...)
Affinity DataIC50:  361nMAssay Description:Inhibition of carbonic anhydrase 4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50317415(6-[(3,4-Difluorophenyl)thio]-5-{[(3-methoxypropyl)...)
Affinity DataIC50:  386nMAssay Description:Inhibition of carbonic anhydrase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 4(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50317413(6-[(3,4-Difluorophenyl)thio]-5-{[(4-methoxybenzyl)...)
Affinity DataIC50:  402nMAssay Description:Inhibition of carbonic anhydrase 4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 4(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50317387(5-(Aminosulfonyl)-N-ethyl-2-(phenylthio)benzamide ...)
Affinity DataIC50:  575nMAssay Description:Inhibition of carbonic anhydrase 4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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