Affinity DataIC50: 660nMAssay Description:Inhibition of rat liver DNA topoisomerase 1 preincubated before addition of DNAMore data for this Ligand-Target Pair
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of rat liver DNA topoisomerase 1 treated simultaneously with DNAMore data for this Ligand-Target Pair
Affinity DataIC50: 2.38E+4nMAssay Description:Inhibition of human DNA topoisomerase 1 at free enzyme stateMore data for this Ligand-Target Pair
Affinity DataIC50: 2.38E+4nMAssay Description:Inhibition of human DNA topoisomerase 1 at free enzyme stateMore data for this Ligand-Target Pair
Affinity DataIC50: 2.38E+4nMAssay Description:Inhibition of human DNA topoisomerase 1-mediated relaxation of supercoiled DNA by gel electrophoresisMore data for this Ligand-Target Pair
Affinity DataIC50: 2.38E+4nMAssay Description:Inhibition of human DNA topoisomerase 1 at free enzyme stateMore data for this Ligand-Target Pair
Affinity DataIC50: 2.38E+4nMAssay Description:Inhibition of human DNA topoisomerase 1 at free enzyme stateMore data for this Ligand-Target Pair
Affinity DataIC50: 2.38E+4nMAssay Description:Inhibition of human DNA topoisomerase 1 at free enzyme stateMore data for this Ligand-Target Pair
Affinity DataIC50: 2.38E+4nMAssay Description:Inhibition of human DNA topoisomerase 1 at free enzyme stateMore data for this Ligand-Target Pair
Affinity DataIC50: 2.38E+4nMAssay Description:Inhibition of human DNA topoisomerase 1 at free enzyme stateMore data for this Ligand-Target Pair
Affinity DataIC50: 2.38E+4nMAssay Description:Inhibition of human DNA topoisomerase 1 at free enzyme stateMore data for this Ligand-Target Pair
Affinity DataIC50: 2.38E+4nMAssay Description:Inhibition of human DNA topoisomerase 1 at free enzyme stateMore data for this Ligand-Target Pair
Affinity DataIC50: 2.38E+4nMAssay Description:Inhibition of human DNA topoisomerase 1 at free enzyme stateMore data for this Ligand-Target Pair
Affinity DataIC50: 2.71E+4nMAssay Description:Inhibition of human DNA topoisomerase 1-mediated relaxation of supercoiled DNA by gel electrophoresisMore data for this Ligand-Target Pair
Affinity DataIC50: 3.27E+4nMAssay Description:Inhibition of human DNA topoisomerase 1-mediated relaxation of supercoiled DNA by gel electrophoresisMore data for this Ligand-Target Pair
Affinity DataIC50: 3.60E+4nMAssay Description:Inhibition of human DNA topoisomerase 1-mediated relaxation of supercoiled DNA by gel electrophoresisMore data for this Ligand-Target Pair
Affinity DataIC50: 4.51E+4nMAssay Description:Inhibition of human DNA topoisomerase 1-mediated relaxation of supercoiled DNA by gel electrophoresisMore data for this Ligand-Target Pair
Affinity DataIC50: 4.86E+4nMAssay Description:Inhibition of human DNA topoisomerase 1-mediated relaxation of supercoiled DNA by gel electrophoresisMore data for this Ligand-Target Pair
Affinity DataIC50: 4.97E+4nMAssay Description:Inhibition of human DNA topoisomerase 1-mediated relaxation of supercoiled DNA by gel electrophoresisMore data for this Ligand-Target Pair
Affinity DataIC50: 5.18E+4nMAssay Description:Inhibition of human DNA topoisomerase 1-mediated relaxation of supercoiled DNA by gel electrophoresisMore data for this Ligand-Target Pair
Affinity DataIC50: 5.30E+4nMAssay Description:Inhibition of human DNA topoisomerase 1-mediated relaxation of supercoiled DNA by gel electrophoresisMore data for this Ligand-Target Pair
Affinity DataIC50: 5.37E+4nMAssay Description:Inhibition of human DNA topoisomerase 1-mediated relaxation of supercoiled DNA by gel electrophoresisMore data for this Ligand-Target Pair
Affinity DataIC50: 1.09E+5nMAssay Description:Inhibition of human DNA topoisomerase 1-mediated relaxation of supercoiled DNA by gel electrophoresisMore data for this Ligand-Target Pair
Affinity DataIC50: 1.11E+5nMAssay Description:Inhibition of human DNA topoisomerase 1-mediated relaxation of supercoiled DNA by gel electrophoresisMore data for this Ligand-Target Pair
Affinity DataIC50: 1.19E+5nMAssay Description:Inhibition of human DNA topoisomerase 1-mediated relaxation of supercoiled DNA by gel electrophoresisMore data for this Ligand-Target Pair
Affinity DataIC50: 1.32E+5nMAssay Description:Inhibition of human DNA topoisomerase 1-mediated relaxation of supercoiled DNA by gel electrophoresisMore data for this Ligand-Target Pair
Affinity DataIC50: 1.60E+5nMAssay Description:Inhibition of human DNA topoisomerase 1-mediated relaxation of supercoiled DNA by gel electrophoresisMore data for this Ligand-Target Pair
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
Stephen F. Austin State University
Curated by ChEMBL
Stephen F. Austin State University
Curated by ChEMBL
Affinity DataIC50: >2.50E+5nMAssay Description:Inhibition of human DNA topoisomerase 2-mediated relaxation of supercoiled DNA by gel electrophoresisMore data for this Ligand-Target Pair
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
Stephen F. Austin State University
Curated by ChEMBL
Stephen F. Austin State University
Curated by ChEMBL
Affinity DataIC50: >2.50E+5nMAssay Description:Inhibition of human DNA topoisomerase 2-mediated relaxation of supercoiled DNA by gel electrophoresisMore data for this Ligand-Target Pair
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
Stephen F. Austin State University
Curated by ChEMBL
Stephen F. Austin State University
Curated by ChEMBL
Affinity DataIC50: >2.50E+5nMAssay Description:Inhibition of human DNA topoisomerase 2-mediated relaxation of supercoiled DNA by gel electrophoresisMore data for this Ligand-Target Pair
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
Stephen F. Austin State University
Curated by ChEMBL
Stephen F. Austin State University
Curated by ChEMBL
Affinity DataIC50: >2.50E+5nMAssay Description:Inhibition of human DNA topoisomerase 2-mediated relaxation of supercoiled DNA by gel electrophoresisMore data for this Ligand-Target Pair
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
Stephen F. Austin State University
Curated by ChEMBL
Stephen F. Austin State University
Curated by ChEMBL
Affinity DataIC50: >2.50E+5nMAssay Description:Inhibition of human DNA topoisomerase 2-mediated relaxation of supercoiled DNA by gel electrophoresisMore data for this Ligand-Target Pair
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
Stephen F. Austin State University
Curated by ChEMBL
Stephen F. Austin State University
Curated by ChEMBL
Affinity DataIC50: >2.50E+5nMAssay Description:Inhibition of human DNA topoisomerase 2-mediated relaxation of supercoiled DNA by gel electrophoresisMore data for this Ligand-Target Pair
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
Stephen F. Austin State University
Curated by ChEMBL
Stephen F. Austin State University
Curated by ChEMBL
Affinity DataIC50: >2.50E+5nMAssay Description:Inhibition of human DNA topoisomerase 2-mediated relaxation of supercoiled DNA by gel electrophoresisMore data for this Ligand-Target Pair
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
Stephen F. Austin State University
Curated by ChEMBL
Stephen F. Austin State University
Curated by ChEMBL
Affinity DataIC50: >2.50E+5nMAssay Description:Inhibition of human DNA topoisomerase 2-mediated relaxation of supercoiled DNA by gel electrophoresisMore data for this Ligand-Target Pair
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
Stephen F. Austin State University
Curated by ChEMBL
Stephen F. Austin State University
Curated by ChEMBL
Affinity DataIC50: >2.50E+5nMAssay Description:Inhibition of human DNA topoisomerase 2-mediated relaxation of supercoiled DNA by gel electrophoresisMore data for this Ligand-Target Pair
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
Stephen F. Austin State University
Curated by ChEMBL
Stephen F. Austin State University
Curated by ChEMBL
Affinity DataIC50: >2.50E+5nMAssay Description:Inhibition of human DNA topoisomerase 2-mediated relaxation of supercoiled DNA by gel electrophoresisMore data for this Ligand-Target Pair
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
Stephen F. Austin State University
Curated by ChEMBL
Stephen F. Austin State University
Curated by ChEMBL
Affinity DataIC50: >2.50E+5nMAssay Description:Inhibition of human DNA topoisomerase 2-mediated relaxation of supercoiled DNA by gel electrophoresisMore data for this Ligand-Target Pair
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
Stephen F. Austin State University
Curated by ChEMBL
Stephen F. Austin State University
Curated by ChEMBL
Affinity DataIC50: >2.50E+5nMAssay Description:Inhibition of human DNA topoisomerase 2-mediated relaxation of supercoiled DNA by gel electrophoresisMore data for this Ligand-Target Pair
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
Stephen F. Austin State University
Curated by ChEMBL
Stephen F. Austin State University
Curated by ChEMBL
Affinity DataIC50: >2.50E+5nMAssay Description:Inhibition of human DNA topoisomerase 2-mediated relaxation of supercoiled DNA by gel electrophoresisMore data for this Ligand-Target Pair
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
Stephen F. Austin State University
Curated by ChEMBL
Stephen F. Austin State University
Curated by ChEMBL
Affinity DataIC50: >2.50E+5nMAssay Description:Inhibition of human DNA topoisomerase 2-mediated relaxation of supercoiled DNA by gel electrophoresisMore data for this Ligand-Target Pair
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
Stephen F. Austin State University
Curated by ChEMBL
Stephen F. Austin State University
Curated by ChEMBL
Affinity DataIC50: >2.50E+5nMAssay Description:Inhibition of human DNA topoisomerase 2-mediated relaxation of supercoiled DNA by gel electrophoresisMore data for this Ligand-Target Pair
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
Stephen F. Austin State University
Curated by ChEMBL
Stephen F. Austin State University
Curated by ChEMBL
Affinity DataIC50: >2.50E+5nMAssay Description:Inhibition of human DNA topoisomerase 2-mediated relaxation of supercoiled DNA by gel electrophoresisMore data for this Ligand-Target Pair
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
Stephen F. Austin State University
Curated by ChEMBL
Stephen F. Austin State University
Curated by ChEMBL
Affinity DataIC50: >2.50E+5nMAssay Description:Inhibition of human DNA topoisomerase 2-mediated relaxation of supercoiled DNA by gel electrophoresisMore data for this Ligand-Target Pair
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
Stephen F. Austin State University
Curated by ChEMBL
Stephen F. Austin State University
Curated by ChEMBL
Affinity DataIC50: >2.50E+5nMAssay Description:Inhibition of human DNA topoisomerase 2-mediated relaxation of supercoiled DNA by gel electrophoresisMore data for this Ligand-Target Pair
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
Stephen F. Austin State University
Curated by ChEMBL
Stephen F. Austin State University
Curated by ChEMBL
Affinity DataIC50: >2.50E+5nMAssay Description:Inhibition of human DNA topoisomerase 2-mediated relaxation of supercoiled DNA by gel electrophoresisMore data for this Ligand-Target Pair
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
Stephen F. Austin State University
Curated by ChEMBL
Stephen F. Austin State University
Curated by ChEMBL
Affinity DataIC50: >2.50E+5nMAssay Description:Inhibition of human DNA topoisomerase 2-mediated relaxation of supercoiled DNA by gel electrophoresisMore data for this Ligand-Target Pair
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
Stephen F. Austin State University
Curated by ChEMBL
Stephen F. Austin State University
Curated by ChEMBL
Affinity DataIC50: >2.50E+5nMAssay Description:Inhibition of human DNA topoisomerase 2-mediated relaxation of supercoiled DNA by gel electrophoresisMore data for this Ligand-Target Pair
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
Stephen F. Austin State University
Curated by ChEMBL
Stephen F. Austin State University
Curated by ChEMBL
Affinity DataIC50: >2.50E+5nMAssay Description:Inhibition of human DNA topoisomerase 2-mediated relaxation of supercoiled DNA by gel electrophoresisMore data for this Ligand-Target Pair
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
Stephen F. Austin State University
Curated by ChEMBL
Stephen F. Austin State University
Curated by ChEMBL
Affinity DataIC50: >2.50E+5nMAssay Description:Inhibition of human DNA topoisomerase 2-mediated relaxation of supercoiled DNA by gel electrophoresisMore data for this Ligand-Target Pair