Compile Data Set for Download or QSAR
Report error Found 13 Enz. Inhib. hit(s) with all data for entry = 50041803
TargetTransient receptor potential cation channel subfamily V member 1(Human)
Universidad De Antioquia

Curated by ChEMBL
LigandPNGBDBM50148573(1-[(2E,4E)-5-(1,3-benzodioxol-5-yl)penta-2,4-dieno...)
Affinity DataEC50:  3.16E+3nMAssay Description:Agonist activity at human TRPV1 expressed in tetracycline-stimulated HEK293 cells assessed as increase in intracellular calcium levels by fluorimetri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily V member 1(Human)
Universidad De Antioquia

Curated by ChEMBL
LigandPNGBDBM50415869(CHEMBL120919)
Affinity DataEC50:  2.51E+3nMAssay Description:Agonist activity at human TRPV1 expressed in tetracycline-stimulated HEK293 cells assessed as increase in intracellular calcium levels by fluorimetri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily V member 1(Human)
Universidad De Antioquia

Curated by ChEMBL
LigandPNGBDBM50415870(PIPERANINE)
Affinity DataEC50:  3.98E+3nMAssay Description:Agonist activity at human TRPV1 expressed in tetracycline-stimulated HEK293 cells assessed as increase in intracellular calcium levels by fluorimetri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily V member 1(Human)
Universidad De Antioquia

Curated by ChEMBL
LigandPNGBDBM50381233(CHEMBL332479)
Affinity DataEC50:  6.31E+3nMAssay Description:Agonist activity at human TRPV1 expressed in tetracycline-stimulated HEK293 cells assessed as increase in intracellular calcium levels by fluorimetri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily V member 1(Human)
Universidad De Antioquia

Curated by ChEMBL
LigandPNGBDBM50415871(ANTIEPILEPSIRINE | ILEPCIMIDE)
Affinity DataEC50:  2.00E+4nMAssay Description:Agonist activity at human TRPV1 expressed in tetracycline-stimulated HEK293 cells assessed as increase in intracellular calcium levels by fluorimetri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily V member 1(Human)
Universidad De Antioquia

Curated by ChEMBL
LigandPNGBDBM20461(Zostrix | (E)-N-[(4-hydroxy-3-methoxyphenyl)methyl...)
Affinity DataEC50:  2.51nMAssay Description:Agonist activity at human TRPV1 expressed in tetracycline-stimulated HEK293 cells assessed as increase in intracellular calcium levels by fluorimetri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetTransient receptor potential cation channel subfamily V member 1(Human)
Universidad De Antioquia

Curated by ChEMBL
LigandPNGBDBM50415872(CHEMBL1094074)
Affinity DataEC50:  10nMAssay Description:Antagonist activity at human TRPV1 expressed in tetracycline-stimulated HEK293 cells assessed as inhibition of capsaicin-induced intracellular calciu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily V member 1(Human)
Universidad De Antioquia

Curated by ChEMBL
LigandPNGBDBM50415873(PIPERLONGUMININE)
Affinity DataEC50:  6.31nMAssay Description:Antagonist activity at human TRPV1 expressed in tetracycline-stimulated HEK293 cells assessed as inhibition of capsaicin-induced intracellular calciu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily V member 1(Human)
Universidad De Antioquia

Curated by ChEMBL
LigandPNGBDBM50415874(CHEMBL1095331)
Affinity DataEC50:  2nMAssay Description:Antagonist activity at human TRPV1 expressed in tetracycline-stimulated HEK293 cells assessed as inhibition of capsaicin-induced intracellular calciu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily V member 1(Human)
Universidad De Antioquia

Curated by ChEMBL
LigandPNGBDBM50415875(CHEMBL1097704)
Affinity DataEC50:  2.51nMAssay Description:Antagonist activity at human TRPV1 expressed in tetracycline-stimulated HEK293 cells assessed as inhibition of capsaicin-induced intracellular calciu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily V member 1(Human)
Universidad De Antioquia

Curated by ChEMBL
LigandPNGBDBM50415876(CHEMBL1096703)
Affinity DataEC50:  2.51nMAssay Description:Antagonist activity at human TRPV1 expressed in tetracycline-stimulated HEK293 cells assessed as inhibition of capsaicin-induced intracellular calciu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily V member 1(Human)
Universidad De Antioquia

Curated by ChEMBL
LigandPNGBDBM50415877(CHEMBL1096704)
Affinity DataEC50:  6.31nMAssay Description:Antagonist activity at human TRPV1 expressed in tetracycline-stimulated HEK293 cells assessed as inhibition of capsaicin-induced intracellular calciu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily V member 1(Human)
Universidad De Antioquia

Curated by ChEMBL
LigandPNGBDBM20284(N-[2-(4-chlorophenyl)ethyl]-7,8-dihydroxy-2,3,4,5-...)
Affinity DataEC50:  2.51E+3nMAssay Description:Antagonist activity at human TRPV1 expressed in tetracycline-stimulated HEK293 cells assessed as inhibition of capsaicin-induced intracellular calciu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)