Compile Data Set for Download or QSAR
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Found 5 Enz. Inhib. hit(s) with all data for entry = 50039180
TargetOrotidine 5'-phosphate decarboxylase(Saccharomyces cerevisiae)
University Health Network

Curated by ChEMBL
LigandPNGBDBM50199178(1-beta-D-ribofuranosyl(3H)pyrimidine-2,4,6-trione ...)
Affinity DataKi:  0.00880nMAssay Description:Inhibition of Saccharomyces cerevisia uridine 5'-monophosphate synthaseMore data for this Ligand-Target Pair
TargetOrotidine 5'-phosphate decarboxylase(Saccharomyces cerevisiae)
University Health Network

Curated by ChEMBL
LigandPNGBDBM50199178(1-beta-D-ribofuranosyl(3H)pyrimidine-2,4,6-trione ...)
Affinity DataKi:  0.00900nM ΔG°:  -63.0kJ/moleT: 2°CAssay Description:Inhibition of Saccharomyces cerevisia uridine 5'-monophosphate synthase after overnight incubation at room temperature by VP-ITC microcalorimetryMore data for this Ligand-Target Pair
TargetOrotidine 5'-phosphate decarboxylase(Saccharomyces cerevisiae)
University Health Network

Curated by ChEMBL
LigandPNGBDBM50378784(CHEMBL1164953)
Affinity DataKi:  5nM ΔG°:  -47.4kJ/moleT: 2°CAssay Description:Inhibition of Saccharomyces cerevisia uridine 5'-monophosphate synthase after overnight incubation at room temperature by VP-ITC microcalorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUridine 5'-monophosphate synthase(Homo sapiens (Human))
University Health Network

Curated by ChEMBL
LigandPNGBDBM50378784(CHEMBL1164953)
Affinity DataKi:  17nM ΔG°:  -44.3kJ/moleT: 2°CAssay Description:Inhibition of human uridine 5'-monophosphate synthase after overnight incubation at room temperature by UV spectroscopyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrotidine-5'-phosphate decarboxylase(Plasmodium falciparum (malaria parasite P. falcipa...)
University Health Network

Curated by ChEMBL
LigandPNGBDBM50378785(CHEMBL1164065)
Affinity DataKi:  9.10E+8nM ΔG°:  -0.234kJ/moleT: 2°CAssay Description:Inhibition of Plasmodium falciparum uridine 5'-monophosphate synthase after overnight incubation at room temperature by VP-ITC microcalorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed