Compile Data Set for Download or QSAR
maximum 50k data
Found 16 Enz. Inhib. hit(s) with all data for entry = 50031987
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Institut Curie

Curated by ChEMBL
LigandPNGBDBM50059889((staurosporine)3-methoxy-2-methyl-4-methylamino-(2...)
Affinity DataIC50:  5nMAssay Description:Inhibition of human GSK3betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Institut Curie

Curated by ChEMBL
LigandPNGBDBM50322830(CHEMBL1210175 | N,8-diphenyl-9H-purin-6-amine)
Affinity DataIC50:  16nMAssay Description:Inhibition of human GSK3betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Institut Curie

Curated by ChEMBL
LigandPNGBDBM50322829(3-(6-(phenylamino)-9H-purin-8-yl)benzonitrile | CH...)
Affinity DataIC50:  26nMAssay Description:Inhibition of human GSK3betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Institut Curie

Curated by ChEMBL
LigandPNGBDBM50059889((staurosporine)3-methoxy-2-methyl-4-methylamino-(2...)
Affinity DataIC50:  35.0nMAssay Description:Inhibition of IGF1RMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMAP kinase-activated protein kinase 2(Homo sapiens (Human))
Institut Curie

Curated by ChEMBL
LigandPNGBDBM50059889((staurosporine)3-methoxy-2-methyl-4-methylamino-(2...)
Affinity DataIC50:  36.3nMAssay Description:Inhibition of MAPKAPK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase receptor TYRO3(Homo sapiens (Human))
Institut Curie

Curated by ChEMBL
LigandPNGBDBM50059889((staurosporine)3-methoxy-2-methyl-4-methylamino-(2...)
Affinity DataIC50:  49.0nMAssay Description:Inhibition of TYRO3/SKYMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Institut Curie

Curated by ChEMBL
LigandPNGBDBM50059889((staurosporine)3-methoxy-2-methyl-4-methylamino-(2...)
Affinity DataIC50:  102nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Institut Curie

Curated by ChEMBL
LigandPNGBDBM50322826(CHEMBL1210406 | N-(8-(naphthalen-2-yl)-9H-purin-6-...)
Affinity DataIC50:  169nMAssay Description:Inhibition of human GSK3betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Institut Curie

Curated by ChEMBL
LigandPNGBDBM50322828(CHEMBL1210310 | N-(8-(3-chlorophenyl)-9H-purin-6-y...)
Affinity DataIC50:  365nMAssay Description:Inhibition of human GSK3betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Institut Curie

Curated by ChEMBL
LigandPNGBDBM50322827(CHEMBL1210405 | N-(8-(3-cyanophenyl)-9H-purin-6-yl...)
Affinity DataIC50:  781nMAssay Description:Inhibition of human GSK3betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Institut Curie

Curated by ChEMBL
LigandPNGBDBM50322825(CHEMBL1210476 | N-(8-(3-cyanophenyl)-9H-purin-6-yl...)
Affinity DataIC50:  1.22E+3nMAssay Description:Inhibition of human GSK3betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Institut Curie

Curated by ChEMBL
LigandPNGBDBM50059889((staurosporine)3-methoxy-2-methyl-4-methylamino-(2...)
Affinity DataIC50:  3.18E+3nMAssay Description:Inhibition of JNK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCasein kinase II subunit alpha(Homo sapiens (Human))
Institut Curie

Curated by ChEMBL
LigandPNGBDBM50059889((staurosporine)3-methoxy-2-methyl-4-methylamino-(2...)
Affinity DataIC50:  3.62E+3nMAssay Description:Inhibition of CK2alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCasein kinase I isoform alpha(Homo sapiens (Human))
Institut Curie

Curated by ChEMBL
LigandPNGBDBM50059889((staurosporine)3-methoxy-2-methyl-4-methylamino-(2...)
Affinity DataIC50:  4.19E+3nMAssay Description:Inhibition of CK1alpha1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 3(Homo sapiens (Human))
Institut Curie

Curated by ChEMBL
LigandPNGBDBM50059889((staurosporine)3-methoxy-2-methyl-4-methylamino-(2...)
Affinity DataIC50:  5.09E+3nMAssay Description:Inhibition of ERK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Institut Curie

Curated by ChEMBL
LigandPNGBDBM50322824(CHEMBL1210477 | N-(8-(naphthalen-2-yl)-9H-purin-6-...)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of human GSK3betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed