Compile Data Set for Download or QSAR
Report error Found 44 Enz. Inhib. hit(s) with all data for entry = 50031896
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50321153BDBM50321153((1-(3-bromobenzoyl)piperidin-4-yl)(4-fluorophenyl)...)
Affinity DataIC50: 2.79E+3nMAssay Description:Inhibition of human 11beta-HSD1 by competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50321171BDBM50321171((1-(3-(dimethylamino)benzoyl)piperidin-4-yl)(4-flu...)
Affinity DataIC50: 3.15E+3nMAssay Description:Inhibition of human 11beta-HSD1 by competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50321164BDBM50321164((1-(4-bromobenzoyl)piperidin-4-yl)(4-fluorophenyl)...)
Affinity DataIC50: 3.30E+3nMAssay Description:Inhibition of human 11beta-HSD1 by competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50321161BDBM50321161((4-(4-fluorobenzoyl)piperidin-1-yl)(p-tolyl)methan...)
Affinity DataIC50: 3.41E+3nMAssay Description:Inhibition of human 11beta-HSD1 by competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50321169BDBM50321169((1-(3,4-dichlorobenzoyl)piperidin-4-yl)(4-fluoroph...)
Affinity DataIC50: 3.52E+3nMAssay Description:Inhibition of human 11beta-HSD1 by competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50321151BDBM50321151((1-benzoylpiperidin-4-yl)(4-fluorophenyl)methanone...)
Affinity DataIC50: 3.61E+3nMAssay Description:Inhibition of human 11beta-HSD1 by competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50321137BDBM50321137((4-(4-fluorobenzoyl)piperidin-1-yl)(3-(trifluorome...)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of human 11beta-HSD1 by competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50321175BDBM50321175((1-(2-chlorobenzoyl)piperidin-4-yl)(4-fluorophenyl...)
Affinity DataIC50: 4.06E+3nMAssay Description:Inhibition of human 11beta-HSD1 by competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50321158BDBM50321158((4-(4-fluorobenzoyl)piperidin-1-yl)(3-methoxypheny...)
Affinity DataIC50: 4.20E+3nMAssay Description:Inhibition of human 11beta-HSD1 by competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50321173BDBM50321173((1-(4-chloro-3-(trifluoromethyl)benzoyl)piperidin-...)
Affinity DataIC50: 4.65E+3nMAssay Description:Inhibition of human 11beta-HSD1 by competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50321167BDBM50321167((4-(4-fluorobenzoyl)piperidin-1-yl)(4-(trifluorome...)
Affinity DataIC50: 5.45E+3nMAssay Description:Inhibition of human 11beta-HSD1 by competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50321142BDBM50321142((4-(4-fluorobenzoyl)piperidin-1-yl)(m-tolyl)methan...)
Affinity DataIC50: 5.93E+3nMAssay Description:Inhibition of human 11beta-HSD1 by competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50321163BDBM50321163((1-(4-chlorobenzoyl)piperidin-4-yl)(4-fluorophenyl...)
Affinity DataIC50: 6.02E+3nMAssay Description:Inhibition of human 11beta-HSD1 by competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50321138BDBM50321138(biphenyl-4-yl(4-(4-fluorobenzoyl)piperidin-1-yl)me...)
Affinity DataIC50: 6.12E+3nMAssay Description:Inhibition of human 11beta-HSD1 by competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50321139BDBM50321139(1-(4-(4-(4-fluorobenzoyl)piperidine-1-carbonyl)phe...)
Affinity DataIC50: 6.88E+3nMAssay Description:Inhibition of human 11beta-HSD1 by competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50321166BDBM50321166((4-(4-fluorobenzoyl)piperidin-1-yl)(o-tolyl)methan...)
Affinity DataIC50: 6.89E+3nMAssay Description:Inhibition of human 11beta-HSD1 by competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50321140BDBM50321140((4-(4-fluorobenzoyl)piperidin-1-yl)(4-(trifluorome...)
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of human 11beta-HSD1 by competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50321154BDBM50321154((1-(3-chlorobenzoyl)piperidin-4-yl)(4-fluorophenyl...)
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of human 11beta-HSD1 by competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50321134BDBM50321134((4-(4-fluorobenzoyl)piperidin-1-yl)(2-fluorophenyl...)
Affinity DataIC50: 7.44E+3nMAssay Description:Inhibition of human 11beta-HSD1 by competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50321141BDBM50321141((1-(3,4-difluorobenzoyl)piperidin-4-yl)(4-fluoroph...)
Affinity DataIC50: 7.50E+3nMAssay Description:Inhibition of human 11beta-HSD1 by competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50321155BDBM50321155((4-(4-fluorobenzoyl)piperidin-1-yl)(3-(trifluorome...)
Affinity DataIC50: 9.06E+3nMAssay Description:Inhibition of human 11beta-HSD1 by competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50321150BDBM50321150((4-(4-fluorobenzoyl)piperidin-1-yl)(4-nitrophenyl)...)
Affinity DataIC50: 9.12E+3nMAssay Description:Inhibition of human 11beta-HSD1 by competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50321168BDBM50321168((1-(2-chloro-4-fluorobenzoyl)piperidin-4-yl)(4-flu...)
Affinity DataIC50: 9.67E+3nMAssay Description:Inhibition of human 11beta-HSD1 by competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50321160BDBM50321160(2-(4-(4-fluorobenzoyl)piperidine-1-carbonyl)benzon...)
Affinity DataIC50: 1.06E+4nMAssay Description:Inhibition of human 11beta-HSD1 by competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50321174BDBM50321174((1-(2-aminobenzoyl)piperidin-4-yl)(4-fluorophenyl)...)
Affinity DataIC50: 1.28E+4nMAssay Description:Inhibition of human 11beta-HSD1 by competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50321133BDBM50321133((4-(4-fluorobenzoyl)piperidin-1-yl)(4-morpholinoph...)
Affinity DataIC50: 1.35E+4nMAssay Description:Inhibition of human 11beta-HSD1 by competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50321149BDBM50321149((4-(4-fluorobenzoyl)piperidin-1-yl)(4-methoxypheny...)
Affinity DataIC50: 1.58E+4nMAssay Description:Inhibition of human 11beta-HSD1 by competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50321152BDBM50321152((4-(4-fluorobenzoyl)piperidin-1-yl)(2-(trifluorome...)
Affinity DataIC50: 1.83E+4nMAssay Description:Inhibition of human 11beta-HSD1 by competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50321132BDBM50321132(piperidine-1,4-diylbis((4-fluorophenyl)methanone) ...)
Affinity DataIC50: 2.18E+4nMAssay Description:Inhibition of human 11beta-HSD1 by competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50321157BDBM50321157((4-(4-fluorobenzoyl)piperidin-1-yl)(3-fluorophenyl...)
Affinity DataIC50: 2.19E+4nMAssay Description:Inhibition of human 11beta-HSD1 by competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50321143BDBM50321143((1-(2,3-dimethoxybenzoyl)piperidin-4-yl)(4-fluorop...)
Affinity DataIC50: 2.32E+4nMAssay Description:Inhibition of human 11beta-HSD1 by competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50321146BDBM50321146((4-(4-fluorobenzoyl)piperidin-1-yl)(2-methoxypheny...)
Affinity DataIC50: 2.36E+4nMAssay Description:Inhibition of human 11beta-HSD1 by competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50321147BDBM50321147((1-(2,4-dimethoxybenzoyl)piperidin-4-yl)(4-fluorop...)
Affinity DataIC50: 2.37E+4nMAssay Description:Inhibition of human 11beta-HSD1 by competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50321170BDBM50321170((4-(4-fluorobenzoyl)piperidin-1-yl)(3-nitrophenyl)...)
Affinity DataIC50: 2.56E+4nMAssay Description:Inhibition of human 11beta-HSD1 by competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50321145BDBM50321145((1-(3,5-difluorobenzoyl)piperidin-4-yl)(4-fluoroph...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human 11beta-HSD1 by competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50321144BDBM50321144((1-(2,3-difluorobenzoyl)piperidin-4-yl)(4-fluoroph...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human 11beta-HSD1 by competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50321159BDBM50321159(N-(3-(4-(4-fluorobenzoyl)piperidine-1-carbonyl)phe...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human 11beta-HSD1 by competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50321165BDBM50321165((4-(4-fluorobenzoyl)piperidin-1-yl)(4-(methylsulfo...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human 11beta-HSD1 by competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50321148BDBM50321148(3-(4-(4-fluorobenzoyl)piperidine-1-carbonyl)benzon...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human 11beta-HSD1 by competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50321162BDBM50321162(4-(4-(4-fluorobenzoyl)piperidine-1-carbonyl)benzon...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human 11beta-HSD1 by competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50321136BDBM50321136(3-(4-(4-fluorobenzoyl)piperidine-1-carbonyl)benzen...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human 11beta-HSD1 by competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50321135BDBM50321135(4-(4-(4-fluorobenzoyl)piperidine-1-carbonyl)benzen...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human 11beta-HSD1 by competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50321156BDBM50321156((4-(4-fluorobenzoyl)piperidin-1-yl)(3-(methylsulfo...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human 11beta-HSD1 by competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50321172BDBM50321172((1-(2,4-dichlorobenzoyl)piperidin-4-yl)(4-fluoroph...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human 11beta-HSD1 by competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed