Compile Data Set for Download or QSAR
Report error Found 28 Enz. Inhib. hit(s) with all data for entry = 50031974
TargetKinesin-like protein KIF11(Human)
Kyoto University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50322591BDBM50322591(3-tert-butyl-9H-carbazole | CHEMBL1170621)
Affinity DataIC50: 240nMAssay Description:Inhibition of human C-terminally His6-tagged microtubule-activated KSP motor domain ATPase activity after 30 mins by luciferase-derived luminescence ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2010
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Kyoto University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50322579BDBM50322579(2-(trifluoromethyl)-9H-carbazole | CHEMBL1173704)
Affinity DataIC50: 260nMAssay Description:Inhibition of human C-terminally His6-tagged microtubule-activated KSP motor domain ATPase activity after 30 mins by luciferase-derived luminescence ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2010
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Kyoto University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50322580BDBM50322580(2-tert-butyl-9H-carbazole | CHEMBL1173703)
Affinity DataIC50: 300nMAssay Description:Inhibition of human C-terminally His6-tagged microtubule-activated KSP motor domain ATPase activity after 30 mins by luciferase-derived luminescence ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2010
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Kyoto University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50322578BDBM50322578(methyl 7-tert-butyl-9H-carbazole-3-carboxylate | C...)
Affinity DataIC50: 390nMAssay Description:Inhibition of human C-terminally His6-tagged microtubule-activated KSP motor domain ATPase activity after 30 mins by luciferase-derived luminescence ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2010
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Kyoto University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50322585BDBM50322585(2-(trifluoromethoxy)-9H-carbazole | CHEMBL1171980)
Affinity DataIC50: 510nMAssay Description:Inhibition of human C-terminally His6-tagged microtubule-activated KSP motor domain ATPase activity after 30 mins by luciferase-derived luminescence ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2010
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Kyoto University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50322584BDBM50322584(2-(difluoromethyl)-9H-carbazole | CHEMBL1170284)
Affinity DataIC50: 870nMAssay Description:Inhibition of human C-terminally His6-tagged microtubule-activated KSP motor domain ATPase activity after 30 mins by luciferase-derived luminescence ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2010
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Kyoto University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50322575BDBM50322575(3-(trifluoromethyl)-9H-carbazole | CHEMBL1170444)
Affinity DataIC50: 950nMAssay Description:Inhibition of human C-terminally His6-tagged microtubule-activated KSP motor domain ATPase activity after 30 mins by luciferase-derived luminescence ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2010
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Kyoto University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50322590BDBM50322590(2-tert-butyl-7-(trifluoromethyl)-9H-carbazole | CH...)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of human C-terminally His6-tagged microtubule-activated KSP motor domain ATPase activity after 30 mins by luciferase-derived luminescence ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2010
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Kyoto University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50322583BDBM50322583(2-isopropyl-9H-carbazole | CHEMBL1170460)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of human C-terminally His6-tagged microtubule-activated KSP motor domain ATPase activity after 30 mins by luciferase-derived luminescence ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2010
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Kyoto University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50322576BDBM50322576(1-(7-methyl-9H-carbazol-3-yl)ethanone | CHEMBL1173...)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of human C-terminally His6-tagged microtubule-activated KSP motor domain ATPase activity after 30 mins by luciferase-derived luminescence ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2010
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Kyoto University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50322598BDBM50322598(2,3,4,11-tetrahydro-1H-benzo[a]carbazole | CHEMBL1...)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of human C-terminally His6-tagged microtubule-activated KSP motor domain ATPase activity after 30 mins by luciferase-derived luminescence ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2010
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Kyoto University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50322582BDBM50322582(2-ethyl-9H-carbazole | CHEMBL1171435)
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of human C-terminally His6-tagged microtubule-activated KSP motor domain ATPase activity after 30 mins by luciferase-derived luminescence ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2010
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Kyoto University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50322586BDBM50322586(2-tert-butoxy-9H-carbazole | CHEMBL1170845)
Affinity DataIC50: 3.20E+3nMAssay Description:Inhibition of human C-terminally His6-tagged microtubule-activated KSP motor domain ATPase activity after 30 mins by luciferase-derived luminescence ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2010
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Kyoto University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50322595BDBM50322595(1-(trifluoromethyl)-9H-carbazole | CHEMBL1169609)
Affinity DataIC50: 3.30E+3nMAssay Description:Inhibition of human C-terminally His6-tagged microtubule-activated KSP motor domain ATPase activity after 30 mins by luciferase-derived luminescence ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2010
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Kyoto University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50322599BDBM50322599(11H-benzo[a]carbazole | CHEMBL1173622)
Affinity DataIC50: 4.60E+3nMAssay Description:Inhibition of human C-terminally His6-tagged microtubule-activated KSP motor domain ATPase activity after 30 mins by luciferase-derived luminescence ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2010
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Kyoto University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50322596BDBM50322596(9-methyl-2-(trifluoromethyl)-9H-carbazole | CHEMBL...)
Affinity DataIC50: 5.60E+3nMAssay Description:Inhibition of human C-terminally His6-tagged microtubule-activated KSP motor domain ATPase activity after 30 mins by luciferase-derived luminescence ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2010
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Kyoto University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50198301BDBM50198301((3aS,10R)-2-butyl-10-(3-hydroxy-phenyl)-3a,4,9,10-...)
Affinity DataIC50: 7.10E+3nMAssay Description:Inhibition of human C-terminally His6-tagged microtubule-activated KSP motor domain ATPase activity after 30 mins by luciferase-derived luminescence ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2010
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Kyoto University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50322577BDBM50322577(6-fluoro-2-methyl-9H-carbazole | CHEMBL1172721)
Affinity DataIC50: 7.50E+3nMAssay Description:Inhibition of human C-terminally His6-tagged microtubule-activated KSP motor domain ATPase activity after 30 mins by luciferase-derived luminescence ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2010
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Kyoto University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50322573BDBM50322573(3-methyl-6-(trifluoromethyl)-9H-carbazole | CHEMBL...)
Affinity DataIC50: 8.80E+3nMAssay Description:Inhibition of human C-terminally His6-tagged microtubule-activated KSP motor domain ATPase activity after 30 mins by luciferase-derived luminescence ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2010
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Kyoto University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50322574BDBM50322574(2-methyl-6-(trifluoromethyl)-9H-carbazole | CHEMBL...)
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of human C-terminally His6-tagged microtubule-activated KSP motor domain ATPase activity after 30 mins by luciferase-derived luminescence ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2010
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Kyoto University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50322589BDBM50322589(7-tert-butyl-9H-carbazole-3-carboxylic acid | CHEM...)
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of human C-terminally His6-tagged microtubule-activated KSP motor domain ATPase activity after 30 mins by luciferase-derived luminescence ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2010
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Kyoto University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50322587BDBM50322587(methyl 9H-carbazole-2-carboxylate | CHEMBL1172394)
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of human C-terminally His6-tagged microtubule-activated KSP motor domain ATPase activity after 30 mins by luciferase-derived luminescence ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2010
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Kyoto University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50322588BDBM50322588(9H-carbazole-2-carbaldehyde | CHEMBL1172395)
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of human C-terminally His6-tagged microtubule-activated KSP motor domain ATPase activity after 30 mins by luciferase-derived luminescence ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2010
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Kyoto University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50322594BDBM50322594(1-tert-butyl-9H-carbazole | CHEMBL1172393)
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of human C-terminally His6-tagged microtubule-activated KSP motor domain ATPase activity after 30 mins by luciferase-derived luminescence ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2010
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Kyoto University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50322592BDBM50322592(9H-carbazole-3-carbaldehyde | CHEMBL1172392)
Affinity DataIC50: 1.70E+4nMAssay Description:Inhibition of human C-terminally His6-tagged microtubule-activated KSP motor domain ATPase activity after 30 mins by luciferase-derived luminescence ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2010
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Kyoto University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50322581BDBM50322581(2-methyl-9H-carbazole | CHEMBL1173640)
Affinity DataIC50: 2.20E+4nMAssay Description:Inhibition of human C-terminally His6-tagged microtubule-activated KSP motor domain ATPase activity after 30 mins by luciferase-derived luminescence ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2010
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Kyoto University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50322593BDBM50322593(1-methyl carbazole | 1-methyl-9H-carbazole | CHEMB...)
Affinity DataIC50: 2.30E+4nMAssay Description:Inhibition of human C-terminally His6-tagged microtubule-activated KSP motor domain ATPase activity after 30 mins by luciferase-derived luminescence ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2010
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Kyoto University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50322597BDBM50322597(7,8,9,10-tetrahydro-5H-benzo[b]carbazole | CHEMBL1...)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of human C-terminally His6-tagged microtubule-activated KSP motor domain ATPase activity after 30 mins by luciferase-derived luminescence ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2010
Entry Details Article
PubMed