Compile Data Set for Download or QSAR
Report error Found 36 Enz. Inhib. hit(s) with all data for entry = 50031981
TargetAutotaxin(Human)
Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50322727BDBM50322727(4-[(4-{[3-(4-Fluorobenzyl)-2,4-dioxo-1,3-thiazolan...)
Affinity DataIC50: 5.70nMAssay Description:Inhibition of 6x-histidine-tagged human recombinant ATX expressed in HEK293 cells assessed as lysophosphatidulcholine releaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2010
Entry Details Article
PubMed
TargetAutotaxin(Human)
Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50322725BDBM50322725(3-[(3-{[3-(4-Fluorobenzyl)-2,4-dioxo-1,3-thiazolan...)
Affinity DataIC50: 12nMAssay Description:Inhibition of 6x-histidine-tagged human recombinant ATX expressed in HEK293 cells assessed as lysophosphatidulcholine releaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2010
Entry Details Article
PubMed
TargetAutotaxin(Human)
Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50322724BDBM50322724(3-[(4-{[3-(4-Fluorobenzyl)-2,4-dioxo-1,3-thiazolan...)
Affinity DataIC50: 28nMAssay Description:Inhibition of 6x-histidine-tagged human recombinant ATX expressed in HEK293 cells assessed as lysophosphatidulcholine releaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2010
Entry Details Article
PubMed
TargetAutotaxin(Human)
Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50322728BDBM50322728(4-[(3-{[3-(4-Fluorobenzyl)-2,4-dioxo-1,3-thiazolan...)
Affinity DataIC50: 30nMAssay Description:Inhibition of 6x-histidine-tagged human recombinant ATX expressed in HEK293 cells assessed as lysophosphatidulcholine releaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2010
Entry Details Article
PubMed
TargetAutotaxin(Human)
Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50322707BDBM50322707(6-amino-4-(4-(dimethylamino)phenyl)-3-(4-isobutylp...)
Affinity DataIC50: 46nMAssay Description:Inhibition of 6x-histidine-tagged human recombinant ATX expressed in HEK293 cells using bisP-nitrophenyl phosphate as a substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2010
Entry Details Article
PubMed
TargetAutotaxin(Human)
Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50322708BDBM50322708(4-[(4-{[3-(4-Fluorobenzyl)-2,4-dioxo-1,3-thiazolan...)
Affinity DataIC50: 56nMAssay Description:Inhibition of 6x-histidine-tagged human recombinant ATX expressed in HEK293 cells using bisP-nitrophenyl phosphate as a substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2010
Entry Details Article
PubMed
TargetAutotaxin(Human)
Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50322706BDBM50322706(3-(4-chlorobenzyl)-5-(3-methoxy-4-(pyridin-4-ylmet...)
Affinity DataIC50: 68nMAssay Description:Inhibition of 6x-histidine-tagged human recombinant ATX expressed in HEK293 cells using bisP-nitrophenyl phosphate as a substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2010
Entry Details Article
PubMed
TargetAutotaxin(Human)
Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50322705BDBM50322705(3-benzyl-5-((1,3-dimethyl-2-oxo-2,3-dihydro-1H-ben...)
Affinity DataIC50: 111nMAssay Description:Inhibition of 6x-histidine-tagged human recombinant ATX expressed in HEK293 cells using bisP-nitrophenyl phosphate as a substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2010
Entry Details Article
PubMed
TargetAutotaxin(Human)
Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50322709BDBM50322709(4-((4-((3-benzyl-2,4-dioxothiazolidin-5-ylidene)me...)
Affinity DataIC50: 161nMAssay Description:Inhibition of 6x-histidine-tagged human recombinant ATX expressed in HEK293 cells using bisP-nitrophenyl phosphate as a substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2010
Entry Details Article
PubMed
TargetAutotaxin(Human)
Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50322710BDBM50322710(4-((4-((3-benzyl-2,4-dioxothiazolidin-5-ylidene)me...)
Affinity DataIC50: 248nMAssay Description:Inhibition of 6x-histidine-tagged human recombinant ATX expressed in HEK293 cells using bisP-nitrophenyl phosphate as a substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2010
Entry Details Article
PubMed
TargetAutotaxin(Human)
Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50322704BDBM50322704(N-(3-chlorophenyl)-2-(6-(1,3-dioxoisoindolin-2-yl)...)
Affinity DataIC50: 261nMAssay Description:Inhibition of 6x-histidine-tagged human recombinant ATX expressed in HEK293 cells using bisP-nitrophenyl phosphate as a substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2010
Entry Details Article
PubMed
TargetAutotaxin(Human)
Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50322703BDBM50322703(4-((2-methoxy-4-((3-(4-nitrobenzyl)-2,4-dioxothiaz...)
Affinity DataIC50: 442nMAssay Description:Inhibition of 6x-histidine-tagged human recombinant ATX expressed in HEK293 cells using bisP-nitrophenyl phosphate as a substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2010
Entry Details Article
PubMed
TargetAutotaxin(Human)
Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50148348BDBM50148348(lysophosphatidic acid | 1-oleoyl lysophosphatidic ...)
Affinity DataIC50: 442nMAssay Description:Inhibition of 6x-histidine-tagged human recombinant ATX expressed in HEK293 cells using bisP-nitrophenyl phosphate as a substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2010
Entry Details Article
PubMed
TargetAutotaxin(Human)
Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50322715BDBM50322715(5-(4-(benzyloxy)benzylidene)-3-(4-fluorobenzyl)thi...)
Affinity DataIC50: 700nMAssay Description:Inhibition of 6x-histidine-tagged human recombinant ATX expressed in HEK293 cells using bisP-nitrophenyl phosphate as a substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2010
Entry Details Article
PubMed
TargetAutotaxin(Human)
Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50322699BDBM50322699(3-((4-((3-(4-fluorobenzyl)-2,4-dioxothiazolidin-5-...)
Affinity DataIC50: 1.07E+3nMAssay Description:Inhibition of 6x-histidine-tagged human recombinant ATX expressed in HEK293 cells assessed as lysophosphatidulcholine releaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2010
Entry Details Article
PubMed
TargetAutotaxin(Human)
Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50322701BDBM50322701(4-((4-((3-(4-fluorobenzyl)-2,4-dioxothiazolidin-5-...)
Affinity DataIC50: 1.63E+3nMAssay Description:Inhibition of 6x-histidine-tagged human recombinant ATX expressed in HEK293 cells assessed as lysophosphatidulcholine releaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2010
Entry Details Article
PubMed
TargetAutotaxin(Human)
Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50322700BDBM50322700(3-((4-((3-(4-fluorobenzyl)-2,4-dioxothiazolidin-5-...)
Affinity DataIC50: 2.05E+3nMAssay Description:Inhibition of 6x-histidine-tagged human recombinant ATX expressed in HEK293 cells assessed as lysophosphatidulcholine releaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2010
Entry Details Article
PubMed
TargetAutotaxin(Human)
Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50322708BDBM50322708(4-[(4-{[3-(4-Fluorobenzyl)-2,4-dioxo-1,3-thiazolan...)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of 6x-histidine-tagged human recombinant ATX expressed in HEK293 cells assessed as lysophosphatidulcholine releaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2010
Entry Details Article
PubMed
TargetAutotaxin(Human)
Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50322723BDBM50322723(methyl4-((4-((3-benzyl-2,4-dioxothiazolidin-5-ylid...)
Affinity DataIC50: 2.69E+3nMAssay Description:Inhibition of 6x-histidine-tagged human recombinant ATX expressed in HEK293 cells using bisP-nitrophenyl phosphate as a substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2010
Entry Details Article
PubMed
TargetAutotaxin(Human)
Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50322716BDBM50322716(3-benzyl-5-(4-(benzyloxy)benzylidene)thiazolidine-...)
Affinity DataIC50: 2.69E+3nMAssay Description:Inhibition of 6x-histidine-tagged human recombinant ATX expressed in HEK293 cells using bisP-nitrophenyl phosphate as a substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2010
Entry Details Article
PubMed
TargetAutotaxin(Human)
Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50322710BDBM50322710(4-((4-((3-benzyl-2,4-dioxothiazolidin-5-ylidene)me...)
Affinity DataIC50: 2.90E+3nMAssay Description:Inhibition of 6x-histidine-tagged human recombinant ATX expressed in HEK293 cells assessed as lysophosphatidulcholine releaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2010
Entry Details Article
PubMed
TargetAutotaxin(Human)
Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50322703BDBM50322703(4-((2-methoxy-4-((3-(4-nitrobenzyl)-2,4-dioxothiaz...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of 6x-histidine-tagged human recombinant ATX expressed in HEK293 cells assessed as lysophosphatidulcholine releaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2010
Entry Details Article
PubMed
TargetAutotaxin(Human)
Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50322729BDBM50322729(2-[(3-{[3-(4-Fluorobenzyl)-2,4-dioxo-1,3-thiazolan...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of 6x-histidine-tagged human recombinant ATX expressed in HEK293 cells assessed as lysophosphatidulcholine releaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2010
Entry Details Article
PubMed
TargetAutotaxin(Human)
Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50322726BDBM50322726(2-[(4-{[3-(4-Fluorobenzyl)-2,4-dioxo-1,3-thiazolan...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of 6x-histidine-tagged human recombinant ATX expressed in HEK293 cells assessed as lysophosphatidulcholine releaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2010
Entry Details Article
PubMed
TargetAutotaxin(Human)
Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50322718BDBM50322718(5-(4-(benzyloxy)-3-methoxybenzylidene)-3-(4-fluoro...)
Affinity DataIC50: 5.87E+3nMAssay Description:Inhibition of 6x-histidine-tagged human recombinant ATX expressed in HEK293 cells using bisP-nitrophenyl phosphate as a substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2010
Entry Details Article
PubMed
TargetAutotaxin(Human)
Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50322702BDBM50322702(4-((4-((3-(4-tert-butylbenzyl)-2,4-dioxothiazolidi...)
Affinity DataIC50: 1.36E+4nMAssay Description:Inhibition of 6x-histidine-tagged human recombinant ATX expressed in HEK293 cells assessed as lysophosphatidulcholine releaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2010
Entry Details Article
PubMed
TargetAutotaxin(Human)
Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50322702BDBM50322702(4-((4-((3-(4-tert-butylbenzyl)-2,4-dioxothiazolidi...)
Affinity DataIC50: 1.82E+4nMAssay Description:Inhibition of 6x-histidine-tagged human recombinant ATX expressed in HEK293 cells using bisP-nitrophenyl phosphate as a substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2010
Entry Details Article
PubMed
TargetAutotaxin(Human)
Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50322721BDBM50322721(methyl4-((2-methoxy-4-((3-(4-nitrobenzyl)-2,4-diox...)
Affinity DataIC50: 6.09E+4nMAssay Description:Inhibition of 6x-histidine-tagged human recombinant ATX expressed in HEK293 cells using bisP-nitrophenyl phosphate as a substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2010
Entry Details Article
PubMed
TargetAutotaxin(Human)
Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50322712BDBM50322712(3-benzyl-5-benzylidenethiazolidine-2,4-dione | CHE...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of 6x-histidine-tagged human recombinant ATX expressed in HEK293 cells using bisP-nitrophenyl phosphate as a substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2010
Entry Details Article
PubMed
TargetAutotaxin(Human)
Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50322722BDBM50322722(methy4-((4-((3-(4-fluorobenzyl)-2,4-dioxothiazolid...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of 6x-histidine-tagged human recombinant ATX expressed in HEK293 cells using bisP-nitrophenyl phosphate as a substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2010
Entry Details Article
PubMed
TargetAutotaxin(Human)
Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50322711BDBM50322711(5-benzylidene-3-(4-fluorobenzyl)thiazolidine-2,4-d...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of 6x-histidine-tagged human recombinant ATX expressed in HEK293 cells using bisP-nitrophenyl phosphate as a substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2010
Entry Details Article
PubMed
TargetAutotaxin(Human)
Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50322719BDBM50322719(3-benzyl-5-(4-(benzyloxy)-3-methoxybenzylidene)thi...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of 6x-histidine-tagged human recombinant ATX expressed in HEK293 cells using bisP-nitrophenyl phosphate as a substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2010
Entry Details Article
PubMed
TargetAutotaxin(Human)
Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50322713BDBM50322713(5-(4-(benzyloxy)benzylidene)-3-(4-tert-butylbenzyl...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of 6x-histidine-tagged human recombinant ATX expressed in HEK293 cells using bisP-nitrophenyl phosphate as a substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2010
Entry Details Article
PubMed
TargetAutotaxin(Human)
Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50322717BDBM50322717(5-(4-(benzyloxy)-3-methoxybenzylidene)-3-(4-nitrob...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of 6x-histidine-tagged human recombinant ATX expressed in HEK293 cells using bisP-nitrophenyl phosphate as a substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2010
Entry Details Article
PubMed
TargetAutotaxin(Human)
Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50322720BDBM50322720(methyl4-((4-((3-(4-tert-butylbenzyl)-2,4-dioxothia...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of 6x-histidine-tagged human recombinant ATX expressed in HEK293 cells using bisP-nitrophenyl phosphate as a substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2010
Entry Details Article
PubMed
TargetAutotaxin(Human)
Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50322714BDBM50322714(5-(4-(benzyloxy)benzylidene)-3-(4-nitrobenzyl)thia...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of 6x-histidine-tagged human recombinant ATX expressed in HEK293 cells using bisP-nitrophenyl phosphate as a substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2010
Entry Details Article
PubMed